Sushrut Waikar | Profiles RNS

Sushrut Waikar, MD

Norman G. Levinsky Professor of Medicine

Boston University School of Medicine

Dept of Medicine

Nephrology

MD, Yale University
MPH, Harvard School of Public Health

Websites

	Brigham and Women's Hospital
	Harvard Catalyst Profile
	Boston Medical Center
	Partners Healthcare
	LinkedIn

Dr. Waikar is a clinician-investigator with interest in acute kidney injury (AKI), chronic kidney disease (CKD), renal replacement therapy, and electrolyte abnormalities. Dr. Waikar's research projects include epidemiologic investigations utilizing large databases as well as translational/patient-oriented research projects. Ongoing studies in my research group include: the epidemiology of AKI and hyponatremia; novel blood and urinary biomarkers of AKI and CKD; and small solute flux during hemodialysis and continuous renal replacement therapy. Dr. Waikar's lab has a number of ongoing observational cohorts with biological sample collection in patients with and at risk for AKI and CKD, including in patients undergoing cardiac surgery, cardiac catheterization, intensive care unit hospitalization, cisplatin chemotherapy, and kidney biopsy.

Section Chief
Boston University School of Medicine
Medicine
Nephrology

BMC Research

(Prenotification) Role of Amphiregulin in kidney fibrosis- DK121200
12/01/2019 - 11/30/2024 (PI)
Washington University NIH-NIDDK
1R01DK121200-01A1

(Prenotification) Harvard Chronic Kidney Disease Research Biopsy Center
09/16/2019 - 08/31/2022 (PI)
NIH-NIDDK

Chan Zuckerberg Science Initiative- CZI
07/01/2019 - 06/30/2022 (PI)
Washington University

(Prenotification) Chronic Kidney Disease Biomarker Discovery and Validation Consortium
09/16/2019 - 07/31/2021 (PI)
Brigham & Women's NIH-NIDDK
5U01DK085660-10

(Prenotification) Electronic Tools to Increase Recognition and Improve Primary Care Management…
09/16/2019 - 07/31/2021 (PI)
Brigham & Women's NIH-NIDDK
5R01DK116898-02

Metabolomics and Renal Functional Reserve
09/15/2019 - 01/31/2021 (PI)
NIH-NIDDK

(Prenotification) Oxalate and the Progression and Complications of CKD
09/16/2019 - 08/30/2020 (PI)
Brigham & Women's NIH-NIDDK
5R01DK103784-04

(Prenotification) Novel human biomarkers of kidney fibrosis
09/16/2019 - 06/30/2020 (PI)
Brigham & Women's NIH-NIDDK
5U01DK104308-05

Role of Mitochondrial Health in Acute and Chronic Kidney Disease in Older…
09/16/2019 - 04/30/2020 (PI)
Northern California Institute for Research and Education NIH-NIA

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Bargagli M, Tio MC, Waikar SS, Ferraro PM. Dietary Oxalate Intake and Kidney Outcomes. Nutrients. 2020 Sep 02; 12(9). PMID: 32887293

Burns RB, Waikar SS, Wachterman MW, Kanjee Z. Management Options for an Older Adult With Advanced Chronic Kidney Disease and Dementia: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2020 Aug 04; 173(3):217-225.View Related Profiles.

Wachterman, Melissa
Waikar, Sushrut

PMID: 32745449

Palsson R, Colona MR, Hoenig MP, Lundquist AL, Novak JE, Perazella MA, Waikar SS. Assessment of Interobserver Reliability of Nephrologist Examination of Urine Sediment. JAMA Netw Open. 2020 Aug 03; 3(8):e2013959. PMID: 32821922

Verma A, Patel AB, Waikar SS. SGLT2 Inhibitor: Not a Traditional Diuretic for Heart Failure. Cell Metab. 2020 Jul 07; 32(1):13-14. PMID: 32640243

Schmidt IM, Verma A, Waikar SS. Circulating plasma angiotensin-converting enzyme 2 concentrations in patients with kidney disease. Eur Heart J. 2020 Jul 01; 41(32):3097-3098. PMID: 32691065

Ayus JC, Fuentes N, Go AS, Achinger SG, Moritz ML, Nigwekar SU, Waikar SS, Negri AL. Chronicity of Uncorrected Hyponatremia and Clinical Outcomes in Older Patients Undergoing Hip Fracture Repair. Front Med (Lausanne). 2020; 7:263. PMID: 32695787

Nuzzo PV, Berchuck JE, Korthauer K, Spisak S, Nassar AH, Abou Alaiwi S, Chakravarthy A, Shen SY, Bakouny Z, Boccardo F, Steinharter J, Bouchard G, Curran CR, Pan W, Baca SC, Seo JH, Lee GM, Michaelson MD, Chang SL, Waikar SS, Sonpavde G, Irizarry RA, Pomerantz M, De Carvalho DD, Choueiri TK, Freedman ML. Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nat Med. 2020 Jul; 26(7):1041-1043. PMID: 32572266

Sise ME, Strohbehn I, Chute D, Corey KE, Fusco DN, Sabbisetti VS, Waikar SS, Chung RT. Low Complement C4 Predicts Improvement of Kidney Function After Direct-Acting Antiviral Therapy for Hepatitis C Virus. Hepatol Commun. 2020 Aug; 4(8):1206-1217. PMID: 32766479

Stern LD, Waikar S. Time to Expand Access and Utilization of Home Dialysis: Lessons From the COVID-19 Pandemic. Mayo Clin Proc. 2020 07; 95(7):1323-1324.View Related Profiles.

Stern, Lauren
Waikar, Sushrut

PMID: 32622441; DOI: 10.1016/j.mayocp.2020.04.038;

Hod T, Freedberg KJ, Motwani SS, Chen M, Frendl G, Leaf DE, Gupta S, Mothi SS, Richards WG, Bueno R, Waikar SS. Acute kidney injury after cytoreductive surgery and hyperthermic intraoperative cisplatin chemotherapy for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2020 May 29. PMID: 32631662

Showing 10 of 177 results. Show More

Sharma S, Kelly YP, Palevsky PM, Waikar SS. Intensity of Renal Replacement Therapy and Duration of Mechanical Ventilation: Secondary Analysis of the Acute Renal Failure Trial Network Study. Chest. 2020 May 26. PMID: 32470389

Koopman JJE, Rennke HG, Leatherwood C, Speyer CB, D'Silva K, McMahon GM, Waikar SS, Costenbader KH. Renal deposits of complement factors as predictors of end-stage renal disease and death in patients with lupus nephritis. Rheumatology (Oxford). 2020 May 15. PMID: 32413140

Li P, Schmidt IM, Sabbisetti V, Tio MC, Opotowsky AR, Waikar SS. Plasma Endothelin-1 and Risk of Death and Hospitalization in Patients Undergoing Maintenance Hemodialysis. Clin J Am Soc Nephrol. 2020 Jun 08; 15(6):784-793. PMID: 32381583

Kwan B, Fuhrer T, Zhang J, Darshi M, Van Espen B, Montemayor D, de Boer IH, Dobre M, Hsu CY, Kelly TN, Raj DS, Rao PS, Saraf SL, Scialla J, Waikar SS, Sharma K, Natarajan L. Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 May 05. PMID: 32387023

Palsson R, Chandraker AK, Curhan GC, Rennke HG, McMahon GM, Waikar SS. The association of calcium oxalate deposition in kidney allografts with graft and patient survival. Nephrol Dial Transplant. 2020 05 01; 35(5):888-894. PMID: 30165691

Hudson JI, Kanayama G, Pope HG, Muse S, Kaufman MJ, Baggish A, Waikar SS. Glomerular Filtration Rate and Supraphysiologic-Dose Anabolic-Androgenic Steroid Use: A Cross-sectional Cohort Study. Am J Kidney Dis. 2020 Jul; 76(1):152-155. PMID: 32362416

Verma A, Patel AB, Upadhyay A, Waikar SS. CREDENCE: Significant Victory for Diabetic Kidney Disease. Trends Endocrinol Metab. 2020 Jun; 31(6):391-393.View Related Profiles.

Upadhyay, Ashish
Waikar, Sushrut

PMID: 32327275

Neves JS, Correa S, Baeta Baptista R, Bigotte Vieira M, Waikar SS, Mc Causland FR. Association of Prediabetes With CKD Progression and Adverse Cardiovascular Outcomes: An Analysis of the CRIC Study. J Clin Endocrinol Metab. 2020 Apr 01; 105(4). PMID: 31943096

Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Gonzalez MC, Coca S, Schrauben SJ, Waikar SS, Ramachandran VS, Shlipak MG, Warady B, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S. Plasma Biomarkers of Tubular Injury and Inflammation Are Associated with CKD Progression in Children. J Am Soc Nephrol. 2020 May; 31(5):1067-1077.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 32234829

Chen Y, Zelnick LR, Wang K, Hoofnagle AN, Becker JO, Hsu CY, Feldman HI, Mehta RC, Lash JP, Waikar SS, Shafi T, Seliger SL, Shlipak MG, Rahman M, Kestenbaum BR. Kidney Clearance of Secretory Solutes Is Associated with Progression of CKD: The CRIC Study. J Am Soc Nephrol. 2020 Apr; 31(4):817-827. PMID: 32205410

Palsson R, Short SAP, Kibbelaar ZA, Amodu A, Stillman IE, Rennke HG, McMahon GM, Waikar SS. Bleeding Complications After Percutaneous Native Kidney Biopsy: Results From the Boston Kidney Biopsy Cohort. Kidney Int Rep. 2020 Apr; 5(4):511-518. PMID: 32274455

Simic P, Kim W, Zhou W, Pierce KA, Chang W, Sykes DB, Aziz NB, Elmariah S, Ngo D, Pajevic PD, Govea N, Kestenbaum BR, de Boer IH, Cheng Z, Christov M, Chun J, Leaf DE, Waikar SS, Tager AM, Gerszten RE, Thadhani RI, Clish CB, Jüppner H, Wein MN, Rhee EP. Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney. J Clin Invest. 2020 Mar 02; 130(3):1513-1526.View Related Profiles.

Elmariah, Sammy
Waikar, Sushrut

PMID: 32065590

Hayek SS, Leaf DE, Samman Tahhan A, Raad M, Sharma S, Waikar SS, Sever S, Camacho A, Wang X, Dande RR, Ibrahim NE, Baron RM, Altintas MM, Wei C, Sheikh-Hamad D, Pan JS, Holliday MW, Januzzi JL, Weisbord SD, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Acute Kidney Injury. N Engl J Med. 2020 01 30; 382(5):416-426. PMID: 31995687

Gupta S, McMahon GM, Motwani SS, Mount DB, Waikar SS. "Pleurex Desalination" in Malignancy-related Ascites: A Novel Mechanism of Hyponatremia. Am J Clin Oncol. 2020 01; 43(1):14-19.View Related Profiles.

Mount, David Bruce
Waikar, Sushrut

PMID: 31592807

Correa S, Pena-Esparragoza JK, Scovner KM, Waikar SS, Mc Causland FR. Myeloperoxidase and the Risk of CKD Progression, Cardiovascular Disease, and Death in the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 Jul; 76(1):32-41. PMID: 31864821

McMahon GM, Amodu A, Sise ME, Mothi SS, Palsson R, Waikar SS. Physician Attitudes on Kidney Biopsies for Research: A Survey Study. Kidney Med. 2020 Jan-Feb; 2(1):82-84. PMID: 32734230

Ku E, Yang W, McCulloch CE, Feldman HI, Go AS, Lash J, Bansal N, He J, Horwitz E, Ricardo AC, Shafi T, Sondheimer J, Townsend RR, Waikar SS, Hsu CY. Race and Mortality in CKD and Dialysis: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 03; 75(3):394-403. PMID: 31732235

Kefaloyianni E, Keerthi Raja MR, Schumacher J, Muthu ML, Krishnadoss V, Waikar SS, Herrlich A. Proximal Tubule-Derived Amphiregulin Amplifies and Integrates Profibrotic EGF Receptor Signals in Kidney Fibrosis. J Am Soc Nephrol. 2019 12; 30(12):2370-2383. PMID: 31676723

Wachterman MW, Leveille T, Keating NL, Simon SR, Waikar SS, Bokhour B. Nephrologists' emotional burden regarding decision-making about dialysis initiation in older adults: a qualitative study. BMC Nephrol. 2019 10 24; 20(1):385.View Related Profiles.

Bokhour, Barbara
Wachterman, Melissa
Simon, Steven R.
Waikar, Sushrut

PMID: 31651262

Feldman CH, Speyer C, Ashby R, Bermas B, Bhattacharyya S, Chakravarty E, Everett B, Ferucci E, Hersh AO, Marty FM, Merola JF, Ramsey-Goldman R, Rovin BH, Son MB, Tarter L, Waikar S, Yazdany J, Weissman JS, Costenbader KH. Development of a Set of Lupus-Specific Ambulatory Care Sensitive, Potentially Preventable Adverse Conditions: A Delphi Consensus Study. Arthritis Care Res (Hoboken). 2019 Oct 18. PMID: 31628721

Wilson PC, Wu H, Kirita Y, Uchimura K, Ledru N, Rennke HG, Welling PA, Waikar SS, Humphreys BD. The single-cell transcriptomic landscape of early human diabetic nephropathy. Proc Natl Acad Sci U S A. 2019 09 24; 116(39):19619-19625. PMID: 31506348

Leaf DE, Waikar SS. IDEAL-ICU in Context. Clin J Am Soc Nephrol. 2019 08 07; 14(8):1264-1267. PMID: 31315886

Efe O, Verma A, Waikar SS. Urinary oxalate as a potential mediator of kidney disease in diabetes mellitus and obesity. Curr Opin Nephrol Hypertens. 2019 07; 28(4):316-320. PMID: 31045662

Leatherwood C, Speyer CB, Feldman CH, D'Silva K, Gómez-Puerta JA, Hoover PJ, Waikar SS, McMahon GM, Rennke HG, Costenbader KH. Clinical characteristics and renal prognosis associated with interstitial fibrosis and tubular atrophy (IFTA) and vascular injury in lupus nephritis biopsies. Semin Arthritis Rheum. 2019 12; 49(3):396-404. PMID: 31277928

Opotowsky AR, Carazo M, Singh MN, Dimopoulos K, Cardona-Estrada DA, Elantably A, Waikar SS, Mc Causland FR, Veldtman G, Grewal J, Gray C, Loukas BN, Rajpal S. Creatinine versus cystatin C to estimate glomerular filtration rate in adults with congenital heart disease: Results of the Boston Adult Congenital Heart Disease Biobank. Am Heart J. 2019 08; 214:142-155. PMID: 31203159

Sekulic M, Waikar S, Motwani SS, Weins A, Rennke HG. Chromogranin A Tubulopathy: Differing Histopathologic Patterns of Acute Tubular Injury in the Setting of Neuroendocrine Neoplasms. Kidney Int Rep. 2019 Aug; 4(8):1085-1093. PMID: 31440699

Sharma S, Christov M, Ix JH, Waikar SS. Clearance of FGF-23 during continuous renal replacement therapy. Hemodial Int. 2019 07; 23(3):366-368. PMID: 31037817

Mc Causland FR, Claggett B, Sabbisetti VS, Jarolim P, Waikar SS. Hypertonic Mannitol for the Prevention of Intradialytic Hypotension: A Randomized Controlled Trial. Am J Kidney Dis. 2019 10; 74(4):483-490. PMID: 31040088

Waikar SS, Srivastava A, Palsson R, Shafi T, Hsu CY, Sharma K, Lash JP, Chen J, He J, Lieske J, Xie D, Zhang X, Feldman HI, Curhan GC. Association of Urinary Oxalate Excretion With the Risk of Chronic Kidney Disease Progression. JAMA Intern Med. 2019 04 01; 179(4):542-551. PMID: 30830167

Waikar SS. Precision nosology versus precision nephrology: defining acute kidney injury, again. Kidney Int. 2019 04; 95(4):741-743. PMID: 30904062

Naik GS, Waikar SS, Johnson AEW, Buchbinder EI, Haq R, Hodi FS, Schoenfeld JD, Ott PA. Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition. J Immunother Cancer. 2019 03 29; 7(1):89. PMID: 30922394

Mendu ML, Ahmed S, Maron JK, Rao SK, Chaguturu SK, May MF, Mutter WP, Burdge KA, Steele DJR, Mount DB, Waikar SS, Weilburg JB, Sequist TD. Development of an electronic health record-based chronic kidney disease registry to promote population health management. BMC Nephrol. 2019 03 01; 20(1):72.View Related Profiles.

Mount, David Bruce
Waikar, Sushrut

PMID: 30823871

Palsson R, Srivastava A, Waikar SS. Performance of the Automated Urinalysis in Diagnosis of Proliferative Glomerulonephritis. Kidney Int Rep. 2019 May; 4(5):723-727. PMID: 31080928

Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Boerger EAS, Mc Causland FR, Eisenga MF, Singh K, Babitt JL, Kellum JA, Palevsky PM, Christov M, Waikar SS. Iron, Hepcidin, and Death in Human AKI. J Am Soc Nephrol. 2019 03; 30(3):493-504. PMID: 30737269

Luo S, Coresh J, Tin A, Rebholz CM, Appel LJ, Chen J, Vasan RS, Anderson AH, Feldman HI, Kimmel PL, Waikar SS, Köttgen A, Evans AM, Levey AS, Inker LA, Sarnak MJ, Grams ME. Serum Metabolomic Alterations Associated with Proteinuria in CKD. Clin J Am Soc Nephrol. 2019 03 07; 14(3):342-353. PMID: 30733224

Kelly YP, Waikar SS, Mendu ML. When to stop renal replacement therapy in anticipation of renal recovery in AKI: The need for consensus guidelines. Semin Dial. 2019 05; 32(3):205-209. PMID: 30690779

Srivastava A, Palsson R, Leaf DE, Higuera A, Chen ME, Palacios P, Baron RM, Sabbisetti V, Hoofnagle AN, Vaingankar SM, Palevsky PM, Waikar SS. Uric Acid and Acute Kidney Injury in the Critically Ill. Kidney Med. 2019 Jan-Feb; 1(1):21-30. PMID: 32734180

Coresh J, Heerspink HJL, Sang Y, Matsushita K, Arnlov J, Astor BC, Black C, Brunskill NJ, Carrero JJ, Feldman HI, Fox CS, Inker LA, Ishani A, Ito S, Jassal S, Konta T, Polkinghorne K, Romundstad S, Solbu MD, Stempniewicz N, Stengel B, Tonelli M, Umesawa M, Waikar SS, Wen CP, Wetzels JFM, Woodward M, Grams ME, Kovesdy CP, Levey AS, Gansevoort RT. Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies. Lancet Diabetes Endocrinol. 2019 02; 7(2):115-127. PMID: 30635225

Palsson R, Chandraker AK, Curhan GC, Rennke HG, McMahon GM, Waikar SS. Erratum. Nephrol Dial Transplant. 2018 Dec 22. PMID: 30590582

Rhee EP, Waikar SS, Rebholz CM, Zheng Z, Perichon R, Clish CB, Evans AM, Avila J, Denburg MR, Anderson AH, Vasan RS, Feldman HI, Kimmel PL, Coresh J. Variability of Two Metabolomic Platforms in CKD. Clin J Am Soc Nephrol. 2019 01 07; 14(1):40-48. PMID: 30573658

Han Z, Xiao Z, Kalantar-Zadeh K, Moradi H, Shafi T, Waikar SS, Quarles LD, Yu Z, Tin A, Coresh J, Kovesdy CP. Validation of a Novel Modified Aptamer-Based Array Proteomic Platform in Patients with End-Stage Renal Disease. Diagnostics (Basel). 2018 Oct 08; 8(4). PMID: 30297602

Poyan Mehr A, Tran MT, Ralto KM, Leaf DE, Washco V, Messmer J, Lerner A, Kher A, Kim SH, Khoury CC, Herzig SJ, Trovato ME, Simon-Tillaux N, Lynch MR, Thadhani RI, Clish CB, Khabbaz KR, Rhee EP, Waikar SS, Berg AH, Parikh SM. De novo NAD+ biosynthetic impairment in acute kidney injury in humans. Nat Med. 2018 09; 24(9):1351-1359. PMID: 30127395

Waikar SS, Rebholz CM, Zheng Z, Hurwitz S, Hsu CY, Feldman HI, Xie D, Liu KD, Mifflin TE, Eckfeldt JH, Kimmel PL, Vasan RS, Bonventre JV, Inker LA, Coresh J. Biological Variability of Estimated GFR and Albuminuria in CKD. Am J Kidney Dis. 2018 10; 72(4):538-546. PMID: 30031564

Srivastava A, Palsson R, Kaze AD, Chen ME, Palacios P, Sabbisetti V, Betensky RA, Steinman TI, Thadhani RI, McMahon GM, Stillman IE, Rennke HG, Waikar SS. The Prognostic Value of Histopathologic Lesions in Native Kidney Biopsy Specimens: Results from the Boston Kidney Biopsy Cohort Study. J Am Soc Nephrol. 2018 08; 29(8):2213-2224. PMID: 29866798

Palsson R, Waikar SS. Renal Functional Reserve Revisited. Adv Chronic Kidney Dis. 2018 05; 25(3):e1-e8. PMID: 29793670

Rajpal S, Alshawabkeh L, Almaddah N, Joyce CM, Shafer K, Gurvitz M, Waikar SS, Mc Causland FR, Landzberg MJ, Opotowsky AR. Association of Albuminuria With Major Adverse Outcomes in Adults With Congenital Heart Disease: Results From the Boston Adult Congenital Heart Biobank. JAMA Cardiol. 2018 04 01; 3(4):308-316. PMID: 29541749

Leaf DE, Siew ED, Eisenga MF, Singh K, Mc Causland FR, Srivastava A, Ikizler TA, Ware LB, Ginde AA, Kellum JA, Palevsky PM, Wolf M, Waikar SS. Fibroblast Growth Factor 23 Associates with Death in Critically Ill Patients. Clin J Am Soc Nephrol. 2018 04 06; 13(4):531-541. PMID: 29519954

Motwani SS, McMahon GM, Humphreys BD, Partridge AH, Waikar SS, Curhan GC. Development and Validation of a Risk Prediction Model for Acute Kidney Injury After the First Course of Cisplatin. J Clin Oncol. 2018 03 01; 36(7):682-688. PMID: 29320311

Waikar SS, McMahon GM. Expanding the Role for Kidney Biopsies in Acute Kidney Injury. Semin Nephrol. 2018 01; 38(1):12-20. PMID: 29291757

Mendu ML, May MF, Kaze AD, Graham DA, Cui S, Chen ME, Shin N, Aizer AA, Waikar SS. Non-tunneled versus tunneled dialysis catheters for acute kidney injury requiring renal replacement therapy: a prospective cohort study. BMC Nephrol. 2017 Dec 04; 18(1):351. PMID: 29202728

Srivastava A, Kaze AD, McMullan CJ, Isakova T, Waikar SS. Uric Acid and the Risks of Kidney Failure and Death in Individuals With CKD. Am J Kidney Dis. 2018 03; 71(3):362-370. PMID: 29132945

Rabadi S, Udo I, Leaf DE, Waikar SS, Christov M. Acute blood loss stimulates fibroblast growth factor 23 production. Am J Physiol Renal Physiol. 2018 01 01; 314(1):F132-F139. PMID: 28877877

Kota SK, Pernicone E, Leaf DE, Stillman IE, Waikar SS, Kota SB. BPI Fold-Containing Family A Member 2/Parotid Secretory Protein Is an Early Biomarker of AKI. J Am Soc Nephrol. 2017 Dec; 28(12):3473-3478. PMID: 28775000

Singh K, Waikar SS, Samal L. Evaluating the feasibility of the KDIGO CKD referral recommendations. BMC Nephrol. 2017 Jul 07; 18(1):223. PMID: 28687072

Sharma S, Waikar SS. Intradialytic hypotension in acute kidney injury requiring renal replacement therapy. Semin Dial. 2017 11; 30(6):553-558. PMID: 28666082

Cardenas-Gonzalez M, Srivastava A, Pavkovic M, Bijol V, Rennke HG, Stillman IE, Zhang X, Parikh S, Rovin BH, Afkarian M, de Boer IH, Himmelfarb J, Waikar SS, Vaidya VS. Identification, Confirmation, and Replication of Novel Urinary MicroRNA Biomarkers in Lupus Nephritis and Diabetic Nephropathy. Clin Chem. 2017 Sep; 63(9):1515-1526. PMID: 28667184

Gerarduzzi C, Kumar RK, Trivedi P, Ajay AK, Iyer A, Boswell S, Hutchinson JN, Waikar SS, Vaidya VS. Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation. JCI Insight. 2017 Apr 20; 2(8). PMID: 28422762

Park M, Hsu CY, Go AS, Feldman HI, Xie D, Zhang X, Mifflin T, Waikar SS, Sabbisetti VS, Bonventre JV, Coresh J, Nelson RG, Kimmel PL, Kusek JW, Rahman M, Schelling JR, Vasan RS, Liu KD. Urine Kidney Injury Biomarkers and Risks of Cardiovascular Disease Events and All-Cause Death: The CRIC Study. Clin J Am Soc Nephrol. 2017 May 08; 12(5):761-771.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 28254771; DOI: 10.2215/CJN.08560816;

Zhao B, Lu Q, Cheng Y, Belcher JM, Siew ED, Leaf DE, Body SC, Fox AA, Waikar SS, Collard CD, Thiessen-Philbrook H, Ikizler TA, Ware LB, Edelstein CL, Garg AX, Choi M, Schaub JA, Zhao H, Lifton RP, Parikh CR. A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):482-490.View Related Profiles.

Body, Simon
Waikar, Sushrut

PMID: 27576016

Emerson SC, Waikar SS, Fuentes C, Bonventre JV, Betensky RA. Biomarker validation with an imperfect reference: Issues and bounds. Stat Methods Med Res. 2018 10; 27(10):2933-2945. PMID: 28166709

Mendu ML, Waikar SS, Rao SK. Kidney Disease Population Health Management in the Era of Accountable Care: A Conceptual Framework for Optimizing Care Across the CKD Spectrum. Am J Kidney Dis. 2017 Jul; 70(1):122-131. PMID: 28132720

Mendu ML, Ciociolo GR, McLaughlin SR, Graham DA, Ghazinouri R, Parmar S, Grossier A, Rosen R, Laskowski KR, Riella LV, Robinson ES, Charytan DM, Bonventre JV, Greenberg JO, Waikar SS. A Decision-Making Algorithm for Initiation and Discontinuation of RRT in Severe AKI. Clin J Am Soc Nephrol. 2017 02 07; 12(2):228-236. PMID: 28119408

Birmingham DJ, Merchant M, Waikar SS, Nagaraja H, Klein JB, Rovin BH. Biomarkers of lupus nephritis histology and flare: deciphering the relevant amidst the noise. Nephrol Dial Transplant. 2017 01 01; 32(suppl_1):i71-i79. PMID: 28391335

Leaf DE, Jacob KA, Srivastava A, Chen ME, Christov M, Jüppner H, Sabbisetti VS, Martin A, Wolf M, Waikar SS. Fibroblast Growth Factor 23 Levels Associate with AKI and Death in Critical Illness. J Am Soc Nephrol. 2017 Jun; 28(6):1877-1885. PMID: 28028134

Hsu CY, Xie D, Waikar SS, Bonventre JV, Zhang X, Sabbisetti V, Mifflin TE, Coresh J, Diamantidis CJ, He J, Lora CM, Miller ER, Nelson RG, Ojo AO, Rahman M, Schelling JR, Wilson FP, Kimmel PL, Feldman HI, Vasan RS, Liu KD. Urine biomarkers of tubular injury do not improve on the clinical model predicting chronic kidney disease progression. Kidney Int. 2017 Jan; 91(1):196-203.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 28029431; DOI: 10.1016/j.kint.2016.09.003;

Singh K, Betensky RA, Wright A, Curhan GC, Bates DW, Waikar SS. A Concept-Wide Association Study of Clinical Notes to Discover New Predictors of Kidney Failure. Clin J Am Soc Nephrol. 2016 12 07; 11(12):2150-2158. PMID: 27927892

Mendu ML, Lundquist A, Aizer AA, Leaf DE, Robinson E, Steele DJ, Waikar SS. Clinical predictors of diagnostic testing utility in the initial evaluation of chronic kidney disease. Nephrology (Carlton). 2016 Oct; 21(10):851-9. PMID: 26610178

Pang P, Abbott M, Chang SL, Abdi M, Chauhan N, Mistri M, Ghofrani J, Fucci QA, Walker C, Leonardi C, Grady S, Halim A, Hoffman R, Lu T, Cao H, Tullius SG, Malek S, Kumar S, Steele G, Kibel A, Freedman BS, Waikar SS, Siedlecki AM. Human vascular progenitor cells derived from renal arteries are endothelial-like and assist in the repair of injured renal capillary networks. Kidney Int. 2017 01; 91(1):129-143. PMID: 27692806

Opotowsky AR, Baraona FR, Mc Causland FR, Loukas B, Landzberg E, Landzberg MJ, Sabbisetti V, Waikar SS. Estimated glomerular filtration rate and urine biomarkers in patients with single-ventricle Fontan circulation. Heart. 2017 03; 103(6):434-442. PMID: 27670967

Leaf DE, Waikar SS. End Points for Clinical Trials in Acute Kidney Injury. Am J Kidney Dis. 2017 Jan; 69(1):108-116. PMID: 27599630

Cui S, Heller HT, Waikar SS, McMahon GM. Needle Size and the Risk of Kidney Biopsy Bleeding Complications. Kidney Int Rep. 2016 Nov; 1(4):324-326. PMID: 29142935

Kefaloyianni E, Muthu ML, Kaeppler J, Sun X, Sabbisetti V, Chalaris A, Rose-John S, Wong E, Sagi I, Waikar SS, Rennke H, Humphreys BD, Bonventre JV, Herrlich A. ADAM17 substrate release in proximal tubule drives kidney fibrosis. JCI Insight. 2016 Aug 18; 1(13). PMID: 27642633

Mendu ML, McMahon GM, Licurse A, Solomon S, Greenberg J, Waikar SS. Electronic Consultations in Nephrology: Pilot Implementation and Evaluation. Am J Kidney Dis. 2016 Nov; 68(5):821-823. PMID: 27503182

Mc Causland FR, Asafu-Adjei J, Betensky RA, Palevsky PM, Waikar SS. Comparison of Urine Output among Patients Treated with More Intensive Versus Less Intensive RRT: Results from the Acute Renal Failure Trial Network Study. Clin J Am Soc Nephrol. 2016 08 08; 11(8):1335-42. PMID: 27449661

Waikar SS, Sabbisetti V, Ärnlöv J, Carlsson AC, Coresh J, Feldman HI, Foster MC, Fufaa GD, Helmersson-Karlqvist J, Hsu CY, Kimmel PL, Larsson A, Liu Y, Lind L, Liu KD, Mifflin TE, Nelson RG, Risérus U, Vasan RS, Xie D, Zhang X, Bonventre JV. Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies. Nephrol Dial Transplant. 2016 Sep; 31(9):1460-70.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 27270293; PMCID: PMC5009290; DOI: 10.1093/ndt/gfw203;

Leaf DE, Body SC, Muehlschlegel JD, McMahon GM, Lichtner P, Collard CD, Shernan SK, Fox AA, Waikar SS. Length Polymorphisms in Heme Oxygenase-1 and AKI after Cardiac Surgery. J Am Soc Nephrol. 2016 Nov; 27(11):3291-3297.View Related Profiles.

Body, Simon
Waikar, Sushrut

PMID: 27257045

Pavkovic M, Robinson-Cohen C, Chua AS, Nicoara O, Cárdenas-González M, Bijol V, Ramachandran K, Hampson L, Pirmohamed M, Antoine DJ, Frendl G, Himmelfarb J, Waikar SS, Vaidya VS. Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423. Toxicol Sci. 2016 07; 152(1):205-13. PMID: 27122240

Leaf DE, Christov M, Jüppner H, Siew E, Ikizler TA, Bian A, Chen G, Sabbisetti VS, Bonventre JV, Cai X, Wolf M, Waikar SS. Fibroblast growth factor 23 levels are elevated and associated with severe acute kidney injury and death following cardiac surgery. Kidney Int. 2016 Apr; 89(4):939-48. PMID: 26924052

Leaf DE, Srivastava A, Zeng X, McMahon GM, Croy HE, Mendu ML, Kachalia A, Waikar SS. Excessive diagnostic testing in acute kidney injury. BMC Nephrol. 2016 Jan 15; 17:9. PMID: 26772980

Waikar SS. Introduction: The Past, Present, and Future of AKI Therapeutics. Semin Nephrol. 2016 Jan; 36(1):7. PMID: 27085730

Mendu ML, Waikar SS. Electronic Health Record Patient Portals in CKD and Hypertension Management: Meaningfully Used? Clin J Am Soc Nephrol. 2015 Nov 06; 10(11):1897-9. PMID: 26493243

Samal L, Wright A, Waikar SS, Linder JA. Nephrology co-management versus primary care solo management for early chronic kidney disease: a retrospective cross-sectional analysis. BMC Nephrol. 2015 Oct 12; 16:162. PMID: 26458541

Craciun FL, Bijol V, Ajay AK, Rao P, Kumar RK, Hutchinson J, Hofmann O, Joshi N, Luyendyk JP, Kusebauch U, Moss CL, Srivastava A, Himmelfarb J, Waikar SS, Moritz RL, Vaidya VS. RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis. J Am Soc Nephrol. 2016 06; 27(6):1702-13.View Related Profiles.

Craciun, Florin
Waikar, Sushrut

PMID: 26449608

Foster MC, Coresh J, Bonventre JV, Sabbisetti VS, Waikar SS, Mifflin TE, Nelson RG, Grams M, Feldman HI, Vasan RS, Kimmel PL, Hsu CY, Liu KD. Urinary Biomarkers and Risk of ESRD in the Atherosclerosis Risk in Communities Study. Clin J Am Soc Nephrol. 2015 Nov 6; 10(11):1956-63.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 26350438; PMCID: PMC4633784; DOI: 10.2215/CJN.02590315;

Kramann R, Fleig SV, Schneider RK, Fabian SL, DiRocco DP, Maarouf O, Wongboonsin J, Ikeda Y, Heckl D, Chang SL, Rennke HG, Waikar SS, Humphreys BD. Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis. J Clin Invest. 2015 Aug 03; 125(8):2935-51. PMID: 26193634

Dasta J, Waikar SS, Xie L, Boklage S, Baser O, Chiodo J, Badawi O. Patterns of treatment and correction of hyponatremia in intensive care unit patients. J Crit Care. 2015 Oct; 30(5):1072-9. PMID: 26209428

Mc Causland FR, Waikar SS. Association of Predialysis Calculated Plasma Osmolarity With Intradialytic Blood Pressure Decline. Am J Kidney Dis. 2015 Sep; 66(3):499-506. PMID: 25975966

Jacob KA, Leaf DE, Dieleman JM, van Dijk D, Nierich AP, Rosseel PM, van der Maaten JM, Hofland J, Diephuis JC, de Lange F, Boer C, Kluin J, Waikar SS. Intraoperative High-Dose Dexamethasone and Severe AKI after Cardiac Surgery. J Am Soc Nephrol. 2015 Dec; 26(12):2947-51. PMID: 25952257

Mendu ML, Lundquist A, Aizer AA, Leaf DE, Robinson E, Steele DJ, Waikar SS. The usefulness of diagnostic testing in the initial evaluation of chronic kidney disease. JAMA Intern Med. 2015 May; 175(5):853-6. PMID: 25730699

Leaf DE, Croy HE, Abrahams SJ, Raed A, Waikar SS. Cathelicidin antimicrobial protein, vitamin D, and risk of death in critically ill patients. Crit Care. 2015 Mar 10; 19:80. PMID: 25887571

Hsu CY, Ballard S, Batlle D, Bonventre JV, Böttinger EP, Feldman HI, Klein JB, Coresh J, Eckfeldt JH, Inker LA, Kimmel PL, Kusek JW, Liu KD, Mauer M, Mifflin TE, Molitch ME, Nelsestuen GL, Rebholz CM, Rovin BH, Sabbisetti VS, Van Eyk JE, Vasan RS, Waikar SS, Whitehead KM, Nelson RG. Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium. Clin J Am Soc Nephrol. 2015 May 7; 10(5):894-902.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 25739849; PMCID: PMC4422251; DOI: 10.2215/CJN.11541114;

Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Rawn JD, Frendl G, Waikar SS. Increased plasma catalytic iron in patients may mediate acute kidney injury and death following cardiac surgery. Kidney Int. 2015 May; 87(5):1046-54. PMID: 25565307

Sharma S, Brugnara C, Betensky RA, Waikar SS. Reductions in red blood cell 2,3-diphosphoglycerate concentration during continuous renal replacment therapy. Clin J Am Soc Nephrol. 2015 Jan 07; 10(1):74-9. PMID: 25538269

Leaf DE, Raed A, Donnino MW, Ginde AA, Waikar SS. Reply: active and native vitamin D in critical illness. Am J Respir Crit Care Med. 2014 Nov 15; 190(10):1194-6. PMID: 25398113

Fufaa GD, Weil EJ, Nelson RG, Hanson RL, Bonventre JV, Sabbisetti V, Waikar SS, Mifflin TE, Zhang X, Xie D, Hsu CY, Feldman HI, Coresh J, Vasan RS, Kimmel PL, Liu KD. Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus. Diabetologia. 2015 Jan; 58(1):188-98.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 25316431; PMCID: PMC4258130; DOI: 10.1007/s00125-014-3389-3;

Leaf DE, Waikar SS. Rosuvastatin for sepsis-associated ARDS. N Engl J Med. 2014 09 04; 371(10):968. PMID: 25184877

Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Waikar SS. Plasma catalytic iron, AKI, and death among critically ill patients. Clin J Am Soc Nephrol. 2014 Nov 07; 9(11):1849-56. PMID: 25189925

Leaf DE, Raed A, Donnino MW, Ginde AA, Waikar SS. Randomized controlled trial of calcitriol in severe sepsis. Am J Respir Crit Care Med. 2014 Sep 01; 190(5):533-41. PMID: 25029202

Mendu ML, Schneider LI, Aizer AA, Singh K, Leaf DE, Lee TH, Waikar SS. Implementation of a CKD checklist for primary care providers. Clin J Am Soc Nephrol. 2014 Sep 05; 9(9):1526-35. PMID: 25135764

Mc Causland F, Wright J, Waikar S. In response to "Association of serum sodium with morbidity and mortality in hospitalized patients undergoing major orthopedic surgery". J Hosp Med. 2014 Sep; 9(9):613. PMID: 24965087

Sabbisetti VS, Waikar SS, Antoine DJ, Smiles A, Wang C, Ravisankar A, Ito K, Sharma S, Ramadesikan S, Lee M, Briskin R, De Jager PL, Ngo TT, Radlinski M, Dear JW, Park KB, Betensky R, Krolewski AS, Bonventre JV. Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes. J Am Soc Nephrol. 2014 Oct; 25(10):2177-86. PMID: 24904085

Mendu ML, Waikar SS. Drug-drug interactions and acute kidney injury: caveat prescriptor. Am J Kidney Dis. 2014 Oct; 64(4):492-4. PMID: 24820318

Mc Causland FR, Wright J, Waikar SS. Association of serum sodium with morbidity and mortality in hospitalized patients undergoing major orthopedic surgery. J Hosp Med. 2014 May; 9(5):297-302. PMID: 24523043

Mc Causland FR, Waikar SS. Optimal dialysate sodium-what is the evidence? Semin Dial. 2014 Mar; 27(2):128-34. PMID: 24450281

Grams ME, Waikar SS, MacMahon B, Whelton S, Ballew SH, Coresh J. Performance and limitations of administrative data in the identification of AKI. Clin J Am Soc Nephrol. 2014 Apr; 9(4):682-9. PMID: 24458075

Nakahira K, Kyung SY, Rogers AJ, Gazourian L, Youn S, Massaro AF, Quintana C, Osorio JC, Wang Z, Zhao Y, Lawler LA, Christie JD, Meyer NJ, Mc Causland FR, Waikar SS, Waxman AB, Chung RT, Bueno R, Rosas IO, Fredenburgh LE, Baron RM, Christiani DC, Hunninghake GM, Choi AM. Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation. PLoS Med. 2013 Dec; 10(12):e1001577; discussion e1001577. PMID: 24391478

Gómez-Puerta JA, Waikar SS, Solomon DH, Liu J, Alarcón GS, Winkelmayer WC, Costenbader KH. Erythropoiesis-stimulating Agent Use among Patients with Lupus Nephritis Approaching End-stage Renal Disease. J Clin Cell Immunol. 2013 Dec 01; 4(6):179. PMID: 24672742

Zeng X, McMahon GM, Brunelli SM, Bates DW, Waikar SS. Incidence, outcomes, and comparisons across definitions of AKI in hospitalized individuals. Clin J Am Soc Nephrol. 2014 Jan; 9(1):12-20. PMID: 24178971

McMahon GM, Zeng X, Waikar SS. A risk prediction score for kidney failure or mortality in rhabdomyolysis. JAMA Intern Med. 2013 Oct 28; 173(19):1821-8. PMID: 24000014

Mc Causland FR, Brunelli SM, Waikar SS. Dialysis dose and intradialytic hypotension: results from the HEMO study. Am J Nephrol. 2013; 38(5):388-96. PMID: 24192428

Ramachandran K, Saikumar J, Bijol V, Koyner JL, Qian J, Betensky RA, Waikar SS, Vaidya VS. Human miRNome profiling identifies microRNAs differentially present in the urine after kidney injury. Clin Chem. 2013 Dec; 59(12):1742-52. PMID: 24153252

Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Imperfect gold standards for biomarker evaluation. Clin Trials. 2013 Oct; 10(5):696-700. PMID: 24006246

Wachterman MW, Marcantonio ER, Davis RB, Cohen RA, Waikar SS, Phillips RS, McCarthy EP. Relationship between the prognostic expectations of seriously ill patients undergoing hemodialysis and their nephrologists. JAMA Intern Med. 2013 Jul 8; 173(13):1206-14.View Related Profiles.

Wachterman, Melissa
Waikar, Sushrut

PMID: 23712681; PMCID: PMC3982381; DOI: 10.1001/jamainternmed.2013.6036;

McCullough PA, Bouchard J, Waikar SS, Siew ED, Endre ZH, Goldstein SL, Koyner JL, Macedo E, Doi K, Di Somma S, Lewington A, Thadhani R, Chakravarthi R, Ice C, Okusa MD, Duranteau J, Doran P, Yang L, Jaber BL, Meehan S, Kellum JA, Haase M, Murray PT, Cruz D, Maisel A, Bagshaw SM, Chawla LS, Mehta RL, Shaw AD, Ronco C. Implementation of novel biomarkers in the diagnosis, prognosis, and management of acute kidney injury: executive summary from the tenth consensus conference of the Acute Dialysis Quality Initiative (ADQI). Contrib Nephrol. 2013; 182:5-12. PMID: 23689652

McCullough PA, Shaw AD, Haase M, Bouchard J, Waikar SS, Siew ED, Murray PT, Mehta RL, Ronco C. Diagnosis of acute kidney injury using functional and injury biomarkers: workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference. Contrib Nephrol. 2013; 182:13-29. PMID: 23689653

Christov M, Waikar SS, Pereira RC, Havasi A, Leaf DE, Goltzman D, Pajevic PD, Wolf M, Jüppner H. Plasma FGF23 levels increase rapidly after acute kidney injury. Kidney Int. 2013 Oct; 84(4):776-85.View Related Profiles.

Havasi, Andrea
Divieti Pajevic, Paola
Waikar, Sushrut

PMID: 23657144; PMCID: PMC3766419; DOI: 10.1038/ki.2013.150;

Leaf DE, Waikar SS, Wolf M, Cremers S, Bhan I, Stern L. Dysregulated mineral metabolism in patients with acute kidney injury and risk of adverse outcomes. Clin Endocrinol (Oxf). 2013 Oct; 79(4):491-8. PMID: 23414198

Palevsky PM, Liu KD, Brophy PD, Chawla LS, Parikh CR, Thakar CV, Tolwani AJ, Waikar SS, Weisbord SD. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury. Am J Kidney Dis. 2013 May; 61(5):649-72. PMID: 23499048

McMahon GM, Waikar SS. Biomarkers in nephrology: Core Curriculum 2013. Am J Kidney Dis. 2013 Jul; 62(1):165-78. PMID: 23455173

Sharma S, Waikar SS. Phosphate balance in continuous venovenous hemofiltration. Am J Kidney Dis. 2013 Jun; 61(6):1043-5. PMID: 23434061

Mc Causland FR, Waikar SS, Brunelli SM. The relevance of dietary sodium in hemodialysis. Nephrol Dial Transplant. 2013 Apr; 28(4):797-802. PMID: 23129821

Waikar SS, Winkelmayer WC. Saving the kidneys by sparing intravenous chloride? JAMA. 2012 Oct 17; 308(15):1583-5. PMID: 23073956

Brunelli SM, Waikar SS, Bateman BT, Chang TI, Lii J, Garg AX, Winkelmayer WC, Choudhry NK. Preoperative statin use and postoperative acute kidney injury. Am J Med. 2012 Dec; 125(12):1195-1204.e3. PMID: 23062398; PMCID: PMC3597342; DOI: 10.1016/j.amjmed.2012.06.021;

Zhou S, Leboff MS, Waikar SS, Glowacki J. Vitamin D metabolism and action in human marrow stromal cells: effects of chronic kidney disease. J Steroid Biochem Mol Biol. 2013 Jul; 136:342-4. PMID: 22989482

Mc Causland FR, Brunelli SM, Waikar SS. Association of smoking with cardiovascular and infection-related morbidity and mortality in chronic hemodialysis. Clin J Am Soc Nephrol. 2012 Nov; 7(11):1827-35. PMID: 22917700

Mc Causland FR, Prior LM, Heher E, Waikar SS. Preservation of blood pressure stability with hypertonic mannitol during hemodialysis initiation. Am J Nephrol. 2012; 36(2):168-74. PMID: 22846598

Hoffmann D, Bijol V, Krishnamoorthy A, Gonzalez VR, Frendl G, Zhang Q, Goering PL, Brown RP, Waikar SS, Vaidya VS. Fibrinogen excretion in the urine and immunoreactivity in the kidney serves as a translational biomarker for acute kidney injury. Am J Pathol. 2012 Sep; 181(3):818-28. PMID: 22819533

Saikumar J, Hoffmann D, Kim TM, Gonzalez VR, Zhang Q, Goering PL, Brown RP, Bijol V, Park PJ, Waikar SS, Vaidya VS. Expression, circulation, and excretion profile of microRNA-21, -155, and -18a following acute kidney injury. Toxicol Sci. 2012 Oct; 129(2):256-67. PMID: 22705808

Leaf DE, Wolf M, Waikar SS, Chase H, Christov M, Cremers S, Stern L. FGF-23 levels in patients with AKI and risk of adverse outcomes. Clin J Am Soc Nephrol. 2012 Aug; 7(8):1217-23. PMID: 22700885

Mizuguchi KA, Mitani A, Waikar SS, Ireland P, Panizales C, Deluke G, Sugarbaker DJ, Bonventre JV, Frendl G. Use of postoperative creatinine to predict sustained kidney injury in patients undergoing mesothelioma surgery. Clin J Am Soc Nephrol. 2012 Jul; 7(7):1071-8. PMID: 22537654

Palevsky PM, Molitoris BA, Okusa MD, Levin A, Waikar SS, Wald R, Chertow GM, Murray PT, Parikh CR, Shaw AD, Go AS, Faubel SG, Kellum JA, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene T, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology. Clin J Am Soc Nephrol. 2012 May; 7(5):844-50.View Related Profiles.

Kaufman, James
Waikar, Sushrut

PMID: 22442182; DOI: 10.2215/CJN.12791211;

Molitoris BA, Okusa MD, Palevsky PM, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene TH, Faubel SG, Kellum JA, Wald R, Chertow GM, Levin A, Waikar SS, Murray PT, Parikh CR, Shaw AD, Go AS, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings. Clin J Am Soc Nephrol. 2012 May; 7(5):856-60.View Related Profiles.

Kaufman, James
Waikar, Sushrut

PMID: 22442184; DOI: 10.2215/CJN.12821211;

Okusa MD, Molitoris BA, Palevsky PM, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Faubel S, Kellum JA, Wald R, Chertow GM, Levin A, Waikar SS, Murray PT, Parikh CR, Shaw AD, Go AS, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene TH, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in acute kidney injury: a report from an NIDDK workshop--prevention trials. Clin J Am Soc Nephrol. 2012 May; 7(5):851-5.View Related Profiles.

Kaufman, James
Waikar, Sushrut

PMID: 22442188; DOI: 10.2215/CJN.12811211;

Mc Causland FR, Waikar SS, Brunelli SM. Increased dietary sodium is independently associated with greater mortality among prevalent hemodialysis patients. Kidney Int. 2012 Jul; 82(2):204-11. PMID: 22418981

Ferguson MA, Waikar SS. Established and emerging markers of kidney function. Clin Chem. 2012 Apr; 58(4):680-9. PMID: 22311920

Mc Causland FR, Tilley BS, Waikar SS. Dialysate sodium and the milieu intérieur. Clin J Am Soc Nephrol. 2012 Jan; 7(1):5-7. PMID: 22173861

Devlin A, Waikar SS, Solomon DH, Lu B, Shaykevich T, Alarcón GS, Winkelmayer WC, Costenbader KH. Variation in initial kidney replacement therapy for end-stage renal disease due to lupus nephritis in the United States. Arthritis Care Res (Hoboken). 2011 Dec; 63(12):1642-53. PMID: 22058067

Mandelbaum T, Scott DJ, Lee J, Mark RG, Malhotra A, Waikar SS, Howell MD, Talmor D. Outcome of critically ill patients with acute kidney injury using the Acute Kidney Injury Network criteria. Crit Care Med. 2011 Dec; 39(12):2659-64. PMID: 21765352

Nigwekar SU, Waikar SS. Diuretics in acute kidney injury. Semin Nephrol. 2011 Nov; 31(6):523-34. PMID: 22099509

Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Imperfect gold standards for kidney injury biomarker evaluation. J Am Soc Nephrol. 2012 Jan; 23(1):13-21. PMID: 22021710

Mc Causland FR, Brunelli SM, Waikar SS. Dialysate sodium, serum sodium and mortality in maintenance hemodialysis. Nephrol Dial Transplant. 2012 Apr; 27(4):1613-8. PMID: 21891777

Krishnamoorthy A, Ajay AK, Hoffmann D, Kim TM, Ramirez V, Campanholle G, Bobadilla NA, Waikar SS, Vaidya VS. Fibrinogen ß-derived Bß(15-42) peptide protects against kidney ischemia/reperfusion injury. Blood. 2011 Aug 18; 118(7):1934-42. PMID: 21685370

Waikar SS, Brunelli SM. Peri-surgical statins lessen acute kidney injury. J Am Soc Nephrol. 2011 May; 22(5):797-9. PMID: 21493777

Waikar SS, Curhan GC, Brunelli SM. Mortality associated with low serum sodium concentration in maintenance hemodialysis. Am J Med. 2011 Jan; 124(1):77-84. PMID: 21187188

Waikar SS, Sabbisetti VS, Bonventre JV. Normalization of urinary biomarkers to creatinine during changes in glomerular filtration rate. Kidney Int. 2010 Sep; 78(5):486-94. PMID: 20555318

Gabardi S, Waikar SS, Martin S, Roberts K, Chen J, Borgi L, Sheashaa H, Dyer C, Malek SK, Tullius SG, Vadivel N, Grafals M, Abdi R, Najafian N, Milford E, Chandraker A. Evaluation of fluoroquinolones for the prevention of BK viremia after renal transplantation. Clin J Am Soc Nephrol. 2010 Jul; 5(7):1298-304. PMID: 20507960

James MT, Wald R, Bell CM, Tonelli M, Hemmelgarn BR, Waikar SS, Chertow GM. Weekend hospital admission, acute kidney injury, and mortality. J Am Soc Nephrol. 2010 May; 21(5):845-51. PMID: 20395373

Ferguson MA, Vaidya VS, Waikar SS, Collings FB, Sunderland KE, Gioules CJ, Bonventre JV. Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. Kidney Int. 2010 Apr; 77(8):708-14. PMID: 19940842

Waikar SS, Winkelmayer WC. Chronic on acute renal failure: long-term implications of severe acute kidney injury. JAMA. 2009 Sep 16; 302(11):1227-9. PMID: 19755705

Waikar SS, Betensky RA, Bonventre JV. Creatinine as the gold standard for kidney injury biomarker studies? Nephrol Dial Transplant. 2009 Nov; 24(11):3263-5. PMID: 19736243

Waikar SS, Mount DB, Curhan GC. Mortality after hospitalization with mild, moderate, and severe hyponatremia. Am J Med. 2009 Sep; 122(9):857-65.View Related Profiles.

Mount, David Bruce
Waikar, Sushrut

PMID: 19699382

Vaidya VS, Ford GM, Waikar SS, Wang Y, Clement MB, Ramirez V, Glaab WE, Troth SP, Sistare FD, Prozialeck WC, Edwards JR, Bobadilla NA, Mefferd SC, Bonventre JV. A rapid urine test for early detection of kidney injury. Kidney Int. 2009 Jul; 76(1):108-14. PMID: 19387469

Waikar SS, Bonventre JV. Creatinine kinetics and the definition of acute kidney injury. J Am Soc Nephrol. 2009 Mar; 20(3):672-9. PMID: 19244578

Winkelmayer WC, Waikar SS, Mogun H, Solomon DH. Nonselective and cyclooxygenase-2-selective NSAIDs and acute kidney injury. Am J Med. 2008 Dec; 121(12):1092-8. PMID: 19028206

Vaidya VS, Waikar SS, Ferguson MA, Collings FB, Sunderland K, Gioules C, Bradwin G, Matsouaka R, Betensky RA, Curhan GC, Bonventre JV. Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci. 2008 Dec; 1(3):200-8. PMID: 19212447

Waikar SS, Bonventre JV. Biomarkers for the diagnosis of acute kidney injury. Nephron Clin Pract. 2008; 109(4):c192-7. PMID: 18802367

Rocuts AK, Waikar SS, Alexander MP, Rennke HG, Singh AK. Acute phosphate nephropathy. Kidney Int. 2009 May; 75(9):987-91. PMID: 18580858

Chertow GM, Waikar SS. Toward the promise of renal replacement therapy. J Am Soc Nephrol. 2008 May; 19(5):839-40. PMID: 18385414

Waikar SS, Liu KD, Chertow GM. Diagnosis, epidemiology and outcomes of acute kidney injury. Clin J Am Soc Nephrol. 2008 May; 3(3):844-61. PMID: 18337550

Waikar SS, Bonventre JV. Biomarkers for the diagnosis of acute kidney injury. Curr Opin Nephrol Hypertens. 2007 Nov; 16(6):557-64. PMID: 18089971

Waikar SS, Curhan GC, Ayanian JZ, Chertow GM. Race and mortality after acute renal failure. J Am Soc Nephrol. 2007 Oct; 18(10):2740-8. PMID: 17855647

Waikar SS, Liu KD, Chertow GM. The incidence and prognostic significance of acute kidney injury. Curr Opin Nephrol Hypertens. 2007 May; 16(3):227-36. PMID: 17420666

Waikar SS, Bonventre JV. Can we rely on blood urea nitrogen as a biomarker to determine when to initiate dialysis? Clin J Am Soc Nephrol. 2006 Sep; 1(5):903-4. PMID: 17699303

Waikar SS, Wald R, Chertow GM, Curhan GC, Winkelmayer WC, Liangos O, Sosa MA, Jaber BL. Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Acute Renal Failure. J Am Soc Nephrol. 2006 Jun; 17(6):1688-94. PMID: 16641149

Wald R, Waikar SS, Liangos O, Pereira BJ, Chertow GM, Jaber BL. Acute renal failure after endovascular vs open repair of abdominal aortic aneurysm. J Vasc Surg. 2006 Mar; 43(3):460-466; discussion 466. PMID: 16520155

Waikar SS, Curhan GC, Wald R, McCarthy EP, Chertow GM. Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol. 2006 Apr; 17(4):1143-50. PMID: 16495376

Kirtane AJ, Leder DM, Waikar SS, Chertow GM, Ray KK, Pinto DS, Karmpaliotis D, Burger AJ, Murphy SA, Cannon CP, Braunwald E, Gibson CM. Serum blood urea nitrogen as an independent marker of subsequent mortality among patients with acute coronary syndromes and normal to mildly reduced glomerular filtration rates. J Am Coll Cardiol. 2005 Jun 07; 45(11):1781-6. PMID: 15936606

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 177 publications over 16 distinct years, with a maximum of 24 publications in 2019 and 2020