Sushrut Waikar, MD
Norman G. Levinsky Professor of Medicine
Boston University Chobanian & Avedisian School of Medicine

MD, Yale University
MPH, Harvard School of Public Health
BA, Amherst College

Sushrut S. Waikar, MD, MPH received a BA in English and Neuroscience at Amherst College, his MD at Yale, and an MPH at Harvard. He is the Norman G. Levinsky Professor of Medicine at Chobanian and Avedisian School of Medicine and Chief of Nephrology at Boston Medical Center. Dr. Waikar's research interests and active projects include epidemiologic, translational, and interventional studies to address novel and clinically important questions in nephrology. Current areas of investigation include optimal diagnostic testing in acute kidney injury and chronic kidney disease; biomarkers of kidney pathology and kidney fibrosis; the identification of relevant targets for interventional trials in kidney disease; and randomized controlled trials. He is a Principal Investigator of several NIH grants including the Kidney Precision Medicine Project (U01 DK133092), Multi-omics and Chronic Kidney Disease: Correlation with Histology (R01 DK108803), Discovery Science Collaborative for CKDu (U01 DK130060), NAD Augmentation to Treat Diabetic Kidney Disease: A Randomized Controlled Trial (U01AG076789) andThe Boston University Kidney and Medical Engineering Program (BU-KIDMEP, R25 DK128858).

Diversity, Equity, Inclusion and Accessibility

Diversity is a defining and fundamental feature of our biology and society. Diversity allowed for evolution and is a prerequisite for our continued growth as a people. My first memories and experiences with diversity came as a four-year-old immigrant to Chicago, IL by way of a relatively homogenous city in central India. Diversity for me began with an intense feeling of otherness: I had black, white, and brown classmates, but I "belonged" to none of them because of my accented and under-developed English. Growing up in a predominantly white and middle-class neighborhood in suburban Chicago, I struggled to feel comfortable in my own skin, which stood out starkly in class pictures. While my experiences as an immigrant are not unique and were in fact privileged compared to so many, they shaped my appreciation and empathy for others who, like me, don't feel like they quite "belong."

As a resident in internal medicine, I had the great fortune of being assigned to a primary care clinic at San Francisco General Hospital, where virtually none of my patients hailed from the "majority," whether in terms of skin color, income, or freedom from addiction. Later, as a trainee in nephrology, I was exposed to the stark disparities in kidney diseases across so many of these same strata. Now as a member and leader at Boston Medical Center, the institution that proudly serves as the region's safety net hospital, I hope to be able to use my position to advance diversity, equity, inclusion, and accessibility across our institution. My activities in pursuit of social justice and DEIA include the following:

- Commitment to highlighting historical instances of subtle racism in nephrology: for over 20 years, kidney function was estimated differently for black vs. non-black individuals through an equation that initially began as a biostatistical/epidemiological adjustment for "best fit." Over the years, it slowly and belatedly dawned on many in our field that singling out black vs. non-black people while estimating organ function perpetuated a racialized view of humanity. My contributions to this discussion in nephrology include 1) co-authorship on a manuscript on race, genetic ancestry, and kidney function estimation (Hsu et al., New Engl J Med 2021); 2) a perspectives piece entitled "Separate and Unequal: Race-Based Algorithms and Implications for Nephrology" (Schmidt and Waikar, J Am Soc Nephrol. 2021) which highlights other examples of subtle racism in our field; and 3) advocating for and helping to implement the race-neutral kidney function estimating equation at Boston Medical Center.

- Scientific activities on minoritized and marginalized populations: I am a Principal Investigator of the Kidney Precision Medicine Project, a study of the molecular underpinnings of common forms of kidney disease that disproportionately afflict minority populations in the United States. Boston Medical Center has been a major contributor to this effort and in particular on emphasiing the need for recruitment of diverse populations and expanding the scientific focus to social determinants of health. I am also a Principal Investigator of the Chronic Kidney Disease of Uncertain Etiology Consortium, a study of a mysterious kidney disease epidemic afflicting poor agricultural communities in Central America and India. Boston University has been a leader in this scientific investigation for many years, and as of 2021 Boston Medical Center along with co-PI's at Stanford and Beth Israel Deaconess Medical Center are leading the efforts as the Renal Science Core to understand the cause(s) of this condition.

Much work remains to be done in our institution. Areas of focus include:
- Increasing the diversitry of our nephrology faculty to better mirror the diversity of the patients we serve
- Recruiting and training a diverse group of fellows in nephrology at Boston Medical Center and nationally
- Community outreach to neighborhoods to enlist non-academic partners in the pursuit of kidney health

Section Chief
Boston University Chobanian & Avedisian School of Medicine

Role of Amphiregulin in kidney fibrosis- DK121200
09/15/2019 - 08/31/2024 (PI)
Washington University National Institutes

Histopathology, outcomes, and biomarkers of advanced chronic
01/01/2022 - 12/31/2023 (PI)
Johnson and Johnson

A Study of the Prevalence of Apolipoprotein L1 (APOL1) Alleles Among Individuals With Proteinuric Kidney Disease Who Are of Recent African Ancestry or Geographic Origin
08/20/2020 - 08/20/2023 (PI)
Vertex Pharmaceuticals

Electronic Tools to Increase Recognition and Improve Primary
09/16/2019 - 07/31/2023 (PI)
Brigham and Womens Hospital National Institute o

A Phase 2a, Open-label, Single-arm, 2-Part Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VX-147 in Adults With APOL1-dependent Focal Segmental Glomerulosclerosis
07/29/2020 - 07/29/2023 (PI)
Vertex Pharmaceuticals

The Boston University Kidney and Medical Engineering Program (BU-KIDMEP)
04/01/2021 - 02/28/2023 (PI)
National Institutes of Health/DHHS/NIH

Boston Kidney Biopsy Cohort - Master Agreement
01/03/2022 - 01/02/2023 (PI)
Natera, Inc.

07/01/2020 - 06/30/2022 (PI)
University of Washington, Seattle NIH-NIDDK

Kidney Physiology Phenotyping in the Kidney Precision Medicine Project
07/01/2020 - 06/30/2022 (PI)
University of Washington, Seattle NIH-NIDDK

Harvard Chronic Kidney Disease Research Biopsy Center_Copy
09/01/2019 - 06/30/2022 (PI)
Brigham and Womens Hospital National Institute o

Showing 10 of 19 results. Show All Results


Yr Title Project-Sub Proj Pubs
2023 The Boston University Kidney and Medical Engineering Program (BU-KIDMEP) 5R25DK128858-03
2022 Boston Chronic Kidney Disease Research Biopsy Center 1U01DK133092-01
2022 NAD Augmentation to Treat Diabetic Kidney Disease: A Randomized Controlled Trial 1U01AG076789-01
2022 Discovery Science Collaborative for CKDu 5U01DK130060-02
2022 The Boston University Kidney and Medical Engineering Program (BU-KIDMEP) 5R25DK128858-02
2022 Multi-Omics and Chronic Kidney Disease: Correlation with Histology 2R01DK108803-06A1
2021 Discovery Science Collaborative for CKDu 1U01DK130060-01
2021 The Boston University Kidney and Medical Engineering Program (BU-KIDMEP) 1R25DK128858-01
2021 Harvard Chronic Kidney Disease Research Biopsy Center 5UH3DK114915-05
2020 Metabolomics and Renal Functional Reserve 5R21DK119751-02
Showing 10 of 48 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Dubin RF, Deo R, Ren Y, Lee H, Shou H, Feldman H, Kimmel P, Waikar SS, Rhee EP, Tin A, Chen J, Coresh J, Go AS, Kelly T, Rao PS, Chen TK, Segal MR, Ganz P. Analytical and Biological Variability of a Commercial Modified Aptamer Assay in Plasma Samples of Patients with Chronic Kidney Disease. J Appl Lab Med. 2023 May 04; 8(3):491-503. PMID: 36705086
  2. Buckley LF, Schmidt IM, Verma A, Palsson R, Adam D, Shah AM, Srivastava A, Waikar SS. Associations Between Kidney Histopathologic Lesions and Incident Cardiovascular Disease in Adults With Chronic Kidney Disease. JAMA Cardiol. 2023 Apr 01; 8(4):357-365.View Related Profiles. PMID: 36884237; PMCID: PMC9996453; DOI: 10.1001/jamacardio.2023.0056;
  3. Hong X, Rosenberg AZ, Heymann J, Yoshida T, Waikar SS, Ilori TO, Wang G, Rebuck H, Pearson C, Wang MC, Winkler CA, Kopp JB, Wang X. Joint associations of pregnancy complications and postpartum maternal renal biomarkers with severe cardiovascular morbidities: A US racially diverse prospective birth cohort study. medRxiv. 2023 Mar 15.View Related Profiles. PMID: 36993418; PMCID: PMC10055449; DOI: 10.1101/2023.03.14.23287276;
  4. Ilori TO, Zhen A, Velani RN, Zhao R, Echouffo-Tcheugui J, Anderson CAM, Waikar SS, Kengne AP. The impact of dietary and lifestyle interventions on blood pressure management in sub-Saharan Africa: a systematic review and metanalysis. J Hypertens. 2023 Jun 01; 41(6):918-925.View Related Profiles. PMID: 36928004; PMCID: PMC10158605; DOI: 10.1097/HJH.0000000000003411;
  5. Schmidt IM, Shohet M, Serrano M, Yadati P, Menn-Josephy H, Ilori T, Eneanya ND, Cleveland Manchanda EC, Waikar SS. Patients' Perspectives on Race and the Use of Race-Based Algorithms in Clinical Decision-Making: a Qualitative Study. J Gen Intern Med. 2023 Feb 22; 1-7.View Related Profiles. PMID: 36811702; PMCID: PMC9945816; DOI: 10.1007/s11606-023-08035-4;
  6. Mc Causland FR, Hsu JY, Himmelfarb J, Ikizler TA, Raj DS, Mehrotra R, Waikar SS, Kimmel PL, Kliger AS, Dember LM, Charytan DM. Effects of Spironolactone on Arrhythmias in Hemodialysis Patients: Secondary Results of the SPin-D Randomized Controlled Trial. Kidney360. 2023 Apr 01; 4(4):e486-e495. PMID: 36763641
  7. Ilori TO, Solarin A, Manmak M, Raji YR, Braimoh R, Kwakyi E, Umeizudike T, Ajepe T, Bolanle O, Ripiye N, Eduful E, Adebile T, Ijeoma C, Mumuni AA, Chern J, Akinpelu M, Ulasi I, Arogundade F, Salako BL, Gbadegesin R, Parekh RS, Dupuis J, Amira CO, Adu D, Anderson CAM, Ojo A, Waikar SS. Rationale and Design of the Diet, CKD, and Apolipoprotein L1 Study in Low-Income and Middle-Income Countries. Kidney Int Rep. 2023 Apr; 8(4):764-774.View Related Profiles. PMID: 37069986; PMCID: PMC10105057; DOI: 10.1016/j.ekir.2023.01.019;
  8. Alostaz M, Correa S, Lundy GS, Waikar SS, Mc Causland FR. Time of hemodialysis and risk of intradialytic hypotension and intradialytic hypertension in maintenance hemodialysis. J Hum Hypertens. 2023 Jan 04. PMID: 36599899
  9. Ferkowicz MJ, Winfree S, Sabo AR, Kamocka MM, Khochare S, Barwinska D, Eadon MT, Cheng YH, Phillips CL, Sutton TA, Kelly KJ, Dagher PC, El-Achkar TM, Dunn KW, Knight R, Lecker S, Stillman I, Mcmahon G, Waikar S, Weins A, Hacohen N, Hoover P, Aulisio M, Cooperman L, Herlitz L, O'toole J, Poggio E, Sedor J, Appelbaum P, Barasch J, Bomback A, D'agati V, Kiryluk K, Mehl K, Shang NS, Weng C, Barisoni L, Alexandrov T, Ashkar T, Barwinska D, Dagher P, Dunn K, Eadon M, Ferkowicz M, Kelly K, Sutton T, Winfree S, Menez S, Parikh C, Rosenberg A, Villalobos P, Slack A, Rosas S, Williams M, Azeloglu E, He CJ, Iyengar R, Parikh S, Anderton C, Pasa-Tolic L, Velickovic D, Oliver GH, Ardayfio J, Bebiak J, Brown K, Campbell T, Campbell C, Hayashi L, Jefferson N, Koewler R, Roberts G, Saul J, Shpigel A, Stutzke EC, Wright L, Miegs L, Pinkeney R, Sealfon R, Troyanskaya O, Tuttle K, Goltsev Y, Lake B, Zhang K, Dobi D, Joanes M, Laszik Z, Nolan G, Schroeder A, Balis U, He O, Hodgin J, Kretzler M, Mariani L, Menon R, Otto E, Schaub J, Steck B, Elder M, Hall D, Kellum J, Kruth M, Murugan R, Palevsky P, Randhawa P, Rosengart M, Sims-Lucas S, Stefanick M, Stull S, Tublin M, Alpers C, Boer I, Fullerton M, Himmelfarb J, Mcclelland R, Mooney S, Shankland S, Williams K, Blank K, Dighe A, Carson J, Dowd F, Drager Z, Sharma K, Zhang G, Kermani A, Lee S, Lu C, Miller T, Moe O, Park H, Sambandam K, Sanchez F, Torrealba J, Robert T, Vazquez M, Wang N, Gaut J, Jain S, Vijayan A, Luciano R, Moledina D, Ugochukwu U, Wilson FP. Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline. Lab Invest. 2021 May; 101(5):661-676. PMID: 36775387
  10. Singh AT, Yen TE, Mothi SS, Waikar SS, Mc Causland FR. Associations of Iron Sucrose and Intradialytic Blood Pressure. Am J Kidney Dis. 2023 Jun; 81(6):647-654. PMID: 36587889
Showing 10 of 267 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 267 publications over 19 distinct years, with a maximum of 41 publications in 2021

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