Sushrut Waikar | Profiles RNS

Sushrut Waikar, MD

Norman G. Levinsky Professor of Medicine

Boston University Chobanian & Avedisian School of Medicine

Medicine

Nephrology

MD, Yale University
MPH, Harvard School of Public Health
BA, Amherst College

Websites

	Boston Medical Center
	Brigham and Women's Hospital
	Harvard Catalyst Profile
	LinkedIn
	ResearchGate

ORCID : 0000-0003-4004-326X

Sushrut S. Waikar, MD, MPH received a BA in English and Neuroscience at Amherst College, his MD at Yale, and an MPH at Harvard. He is the Norman G. Levinsky Professor of Medicine at Chobanian and Avedisian School of Medicine and Chief of Nephrology at Boston Medical Center. Dr. Waikar's research interests and active projects include epidemiologic, translational, and interventional studies to address novel and clinically important questions in nephrology. Current areas of investigation include optimal diagnostic testing in acute kidney injury and chronic kidney disease; biomarkers of kidney pathology and kidney fibrosis; the identification of relevant targets for interventional trials in kidney disease; and randomized controlled trials. He is a Principal Investigator of several NIH grants including the Kidney Precision Medicine Project (U01 DK133092), Multi-omics and Chronic Kidney Disease: Correlation with Histology (R01 DK108803), Discovery Science Collaborative for CKDu (U01 DK130060), NAD Augmentation to Treat Diabetic Kidney Disease: A Randomized Controlled Trial (U01AG076789) andThe Boston University Kidney and Medical Engineering Program (BU-KIDMEP, R25 DK128858).

Diversity, Equity, Inclusion and Accessibility

Diversity is a defining and fundamental feature of our biology and society. Diversity allowed for evolution and is a prerequisite for our continued growth as a people. My first memories and experiences with diversity came as a four-year-old immigrant to Chicago, IL by way of a relatively homogenous city in central India. Diversity for me began with an intense feeling of otherness: I had black, white, and brown classmates, but I "belonged" to none of them because of my accented and under-developed English. Growing up in a predominantly white and middle-class neighborhood in suburban Chicago, I struggled to feel comfortable in my own skin, which stood out starkly in class pictures. While my experiences as an immigrant are not unique and were in fact privileged compared to so many, they shaped my appreciation and empathy for others who, like me, don't feel like they quite "belong."

As a resident in internal medicine, I had the great fortune of being assigned to a primary care clinic at San Francisco General Hospital, where virtually none of my patients hailed from the "majority," whether in terms of skin color, income, or freedom from addiction. Later, as a trainee in nephrology, I was exposed to the stark disparities in kidney diseases across so many of these same strata. Now as a member and leader at Boston Medical Center, the institution that proudly serves as the region's safety net hospital, I hope to be able to use my position to advance diversity, equity, inclusion, and accessibility across our institution. My activities in pursuit of social justice and DEIA include the following:

- Commitment to highlighting historical instances of subtle racism in nephrology: for over 20 years, kidney function was estimated differently for black vs. non-black individuals through an equation that initially began as a biostatistical/epidemiological adjustment for "best fit." Over the years, it slowly and belatedly dawned on many in our field that singling out black vs. non-black people while estimating organ function perpetuated a racialized view of humanity. My contributions to this discussion in nephrology include 1) co-authorship on a manuscript on race, genetic ancestry, and kidney function estimation (Hsu et al., New Engl J Med 2021); 2) a perspectives piece entitled "Separate and Unequal: Race-Based Algorithms and Implications for Nephrology" (Schmidt and Waikar, J Am Soc Nephrol. 2021) which highlights other examples of subtle racism in our field; and 3) advocating for and helping to implement the race-neutral kidney function estimating equation at Boston Medical Center.

- Scientific activities on minoritized and marginalized populations: I am a Principal Investigator of the Kidney Precision Medicine Project, a study of the molecular underpinnings of common forms of kidney disease that disproportionately afflict minority populations in the United States. Boston Medical Center has been a major contributor to this effort and in particular on emphasiing the need for recruitment of diverse populations and expanding the scientific focus to social determinants of health. I am also a Principal Investigator of the Chronic Kidney Disease of Uncertain Etiology Consortium, a study of a mysterious kidney disease epidemic afflicting poor agricultural communities in Central America and India. Boston University has been a leader in this scientific investigation for many years, and as of 2021 Boston Medical Center along with co-PI's at Stanford and Beth Israel Deaconess Medical Center are leading the efforts as the Renal Science Core to understand the cause(s) of this condition.

Much work remains to be done in our institution. Areas of focus include:
- Increasing the diversitry of our nephrology faculty to better mirror the diversity of the patients we serve
- Recruiting and training a diverse group of fellows in nephrology at Boston Medical Center and nationally
- Community outreach to neighborhoods to enlist non-academic partners in the pursuit of kidney health

Section Chief
Boston University Chobanian & Avedisian School of Medicine
Medicine
Nephrology

BMC Research
NIH RePORTER Research

Pre-Notification transfer from USF for Jie Zhang Significance of Tubuloglomerular Feedback in SGLT1 and SGLT2 Inhibition in Diabetic Kidney Disease
04/01/2023 - 03/31/2028 (PI)
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS

Multi-Omics and Chronic Kidney Disease: Correlation with Histology
07/15/2022 - 06/30/2027 (PI)
New York University Health Resources and

NAD Augmentation to Treat Diabetic Kidney Disease: A Randomized Controlled Trial
08/01/2022 - 07/31/2025 (PI)
Brigham and Womens Hospital National Institutes
1U01AG076789-01

Role of Amphiregulin in kidney fibrosis- DK121200
09/15/2019 - 08/31/2024 (PI)
Washington University National Institutes
5R01DK121200-03

A Study of the Prevalence of Apolipoprotein L1 (APOL1) Alleles Among Individuals With Proteinuric Kidney Disease Who Are of Recent African Ancestry or Geographic Origin
08/20/2020 - 08/20/2024 (PI)
Vertex Pharmaceuticals

Boston Chronic Kidney Disease Research Biopsy Center
09/15/2022 - 06/30/2024 (PI)
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
1U01DK133092-01

Discovery Science Collaborative for CKDu
08/25/2021 - 06/30/2024 (PI)
Stanford University National Institute o
5U01DK130060-03

Biomarker-based Diagnostic Algorithms to Prevent, Detect, and Guide Treatment of Kidney Disease in Persons Living with HIV
09/01/2021 - 05/31/2024 (PI)
Northern California Institute for Research and Education National Institute o
5R01AG034853-13

Role of Mitochondrial Health in Acute and Chronic Kidney Disease in Older…
09/16/2019 - 04/30/2024 (PI)
Northern California Institute for Research and Education National Institutes
5R01AG027002-14

Measuring podocyte urinary biomarkers across renal disorders
04/06/2022 - 04/05/2024 (PI)
Pfizer, Inc

Showing 10 of 25 results. Show All Results

Title

Yr	Title	Project-Sub Proj
2023	Boston Chronic Kidney Disease Research Biopsy Center	5U01DK133092-02
2023	NAD Augmentation to Treat Diabetic Kidney Disease: A Randomized Controlled Trial	5U01AG076789-02
2023	Discovery Science Collaborative for CKDu	5U01DK130060-03
2023	The Boston University Kidney and Medical Engineering Program (BU-KIDMEP)	5R25DK128858-03
2023	Multi-Omics and Chronic Kidney Disease: Correlation with Histology	5R01DK108803-07
2022	Boston Chronic Kidney Disease Research Biopsy Center	1U01DK133092-01
2022	NAD Augmentation to Treat Diabetic Kidney Disease: A Randomized Controlled Trial	1U01AG076789-01
2022	Discovery Science Collaborative for CKDu	5U01DK130060-02
2022	The Boston University Kidney and Medical Engineering Program (BU-KIDMEP)	5R25DK128858-02
2022	Multi-Omics and Chronic Kidney Disease: Correlation with Histology	2R01DK108803-06A1

Showing 10 of 52 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Buckley L, Palsson R, Waikar SS. Linking Kidney Vessel Scarring to Cardiovascular Risk-Reply. JAMA Cardiol. 2023 Oct 01; 8(10):1000. PMID: 37672259

Zhu K, Mukherjee K, Wei C, Hayek SS, Collins A, Gu C, Corapi K, Altintas MM, Wang Y, Waikar SS, Bianco AC, Koch A, Tacke F, Reiser J, Sever S. The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease. Sci Transl Med. 2023 Sep 20; 15(714):eabq6492. PMID: 37729431

Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma VS, Kwan B, Waikar SS, Himmelfarb J, Tuttle KR, Kestenbaum B, Fuhrer T, Feldman H, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto EA, Hodgin JB, Kretzler M, Anderton CR, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R. Endogenous adenine mediates kidney injury in diabetic models and predicts diabetic kidney disease in patients. J Clin Invest. 2023 Aug 24. PMID: 37616058

Ferkowicz MJ, Verma A, Barwinska D, Ferreira RM, Henderson JM, Kirkpatrick M, Silva PS, Steenkamp DW, Phillips CL, Waikar SS, Sutton TA. Molecular Signatures of Glomerular Neovascularization in a Patient with Diabetic Kidney Disease. Clin J Am Soc Nephrol. 2023 Aug 03.View Related Profiles.

Verma, Ashish
Steenkamp, Devin
Henderson, Joel
Waikar, Sushrut

PMID: 37533147; DOI: 10.2215/CJN.0000000000000276;

Vasquez-Rios G, Katz R, Levitan EB, Cushman M, Parikh CR, Kimmel PL, Bonventre JV, Waikar SS, Schrauben SJ, Greenberg JH, Sarnak MJ, Ix JH, Shlipak MG, Gutierrez OM. Urinary Biomarkers of Kidney Tubule Health and Mortality in Persons with CKD and Diabetes Mellitus. Kidney360. 2023 Sep 01; 4(9):e1257-e1264. PMID: 37533144; PMCID: PMC10547219; DOI: 10.34067/KID.0000000000000226;

Rizzolo K, Gonzalez Jauregui R, Barrientos I, Teakell J, Camacho C, Chonchol M, Waikar SS, Cervantes L. Barriers and Facilitators to Home Dialysis Among Latinx Patients with Kidney Disease. JAMA Netw Open. 2023 Aug 01; 6(8):e2328944.View Related Profiles.

Rizzolo, Katherine
Waikar, Sushrut

PMID: 37581885; PMCID: PMC10427944; DOI: 10.1001/jamanetworkopen.2023.28944;

Lake BB, Menon R, Winfree S, Hu Q, Ferreira RM, Kalhor K, Barwinska D, Otto EA, Ferkowicz M, Diep D, Plongthongkum N, Knoten A, Urata S, Mariani LH, Naik AS, Eddy S, Zhang B, Wu Y, Salamon D, Williams JC, Wang X, Balderrama KS, Hoover PJ, Murray E, Marshall JL, Noel T, Vijayan A, Hartman A, Chen F, Waikar SS, Rosas SE, Wilson FP, Palevsky PM, Kiryluk K, Sedor JR, Toto RD, Parikh CR, Kim EH, Satija R, Greka A, Macosko EZ, Kharchenko PV, Gaut JP, Hodgin JB, Eadon MT, Dagher PC, El-Achkar TM, Zhang K, Kretzler M, Jain S. An atlas of healthy and injured cell states and niches in the human kidney. Nature. 2023 Jul; 619(7970):585-594. PMID: 37468583; PMCID: PMC10356613; DOI: 10.1038/s41586-023-05769-3;

Menon R, Otto EA, Barisoni L, Ferreira RM, Limonte CP, Godfrey B, Eichinger F, Nair V, Naik AS, Subramanian L, D'Agati V, Henderson JM, Herlitz L, Kiryluk K, Moledina DG, Moeckel GW, Palevsky PM, Parikh CR, Randhawa P, Rosas SE, Rosenberg AZ, Stillman I, Toto R, Torrealba J, Vazquez MA, Waikar S, Alpers CE, Nelson RG, Eadon MT, Kretzler M, Hodgin JB. Defining the molecular correlate of arteriolar hyalinosis in kidney disease progression by integration of single cell transcriptomic analysis and pathology scoring. medRxiv. 2023 Jun 14.View Related Profiles.

Henderson, Joel
Waikar, Sushrut

PMID: 37398386; PMCID: PMC10312894; DOI: 10.1101/2023.06.14.23291150;

Jiang K, Greenberg JH, Abraham A, Xu Y, Schelling JR, Feldman HI, Schrauben SJ, Waikar SS, Shlipak MG, Wettersten N, Coca SG, Vasan RS, Gutierrez OM, Ix JH, Warady BA, Kimmel PL, Bonventre JV, Parikh CR, Mitsnefes MM, Denburg MR, Furth S. Associations of Biomarkers of Kidney Tubule Health, Injury, and Inflammation with Left Ventricular Hypertrophy in Children with CKD. Kidney360. 2023 Aug 01; 4(8):1039-1047. PMID: 37303083; PMCID: PMC10476681; DOI: 10.34067/KID.0000000000000183;

Sharma K, Zhang G, Hansen J, Bjornstad P, Lee HJ, Menon R, Hejazi L, Liu JJ, Franzone A, Looker HC, Choi BY, Fernandez R, Venkatachalam MA, Kugathasan L, Sridhar VS, Natarajan L, Zhang J, Sharma V, Kwan B, Waikar S, Himmelfarb J, Tuttle K, Kestenbaum B, Fuhrer T, Feldman H, de Boer IH, Tucci FC, Sedor J, Heerspink HL, Schaub J, Otto E, Hodgin JB, Kretzler M, Anderton C, Alexandrov T, Cherney D, Lim SC, Nelson RG, Gelfond J, Iyengar R. Role of endogenous adenine in kidney failure and mortality with diabetes. medRxiv. 2023 Jun 04. PMID: 37398187; PMCID: PMC10312877; DOI: 10.1101/2023.05.31.23290681;

Showing 10 of 279 results. Show More

Claudel SE, Waikar SS, Schmidt IM, Verma A. Kidney Disease-Related Mortality Among Asian Americans. Kidney Med. 2023 Aug; 5(8):100676.View Related Profiles.

Verma, Ashish
Schmidt, Insa
Claudel, Sophie
Waikar, Sushrut

PMID: 37576431; PMCID: PMC10421978; DOI: 10.1016/j.xkme.2023.100676;

Ku E, Del Vecchio L, Eckardt KU, Haase VH, Johansen KL, Nangaku M, Tangri N, Waikar SS, Wiecek A, Cheung M, Jadoul M, Winkelmayer WC, Wheeler DC. Novel anemia therapies in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2023 Oct; 104(4):655-680. PMID: 37236424

Dubin RF, Deo R, Ren Y, Lee H, Shou H, Feldman H, Kimmel P, Waikar SS, Rhee EP, Tin A, Chen J, Coresh J, Go AS, Kelly T, Rao PS, Chen TK, Segal MR, Ganz P. Analytical and Biological Variability of a Commercial Modified Aptamer Assay in Plasma Samples of Patients with Chronic Kidney Disease. J Appl Lab Med. 2023 May 04; 8(3):491-503. PMID: 36705086

Buckley LF, Schmidt IM, Verma A, Palsson R, Adam D, Shah AM, Srivastava A, Waikar SS. Associations Between Kidney Histopathologic Lesions and Incident Cardiovascular Disease in Adults With Chronic Kidney Disease. JAMA Cardiol. 2023 Apr 01; 8(4):357-365.View Related Profiles.

Verma, Ashish
Schmidt, Insa
Waikar, Sushrut

PMID: 36884237; PMCID: PMC9996453; DOI: 10.1001/jamacardio.2023.0056;

Hong X, Rosenberg AZ, Heymann J, Yoshida T, Waikar SS, Ilori TO, Wang G, Rebuck H, Pearson C, Wang MC, Winkler CA, Kopp JB, Wang X. Joint associations of pregnancy complications and postpartum maternal renal biomarkers with severe cardiovascular morbidities: A US racially diverse prospective birth cohort study. medRxiv. 2023 Mar 15.View Related Profiles.

Waikar, Sushrut
Ilori, Titilayo

PMID: 36993418; PMCID: PMC10055449; DOI: 10.1101/2023.03.14.23287276;

Ilori TO, Zhen A, Velani RN, Zhao R, Echouffo-Tcheugui J, Anderson CAM, Waikar SS, Kengne AP. The impact of dietary and lifestyle interventions on blood pressure management in sub-Saharan Africa: a systematic review and metanalysis. J Hypertens. 2023 Jun 01; 41(6):918-925.View Related Profiles.

Zhen, Aileen
Waikar, Sushrut
Ilori, Titilayo

PMID: 36928004; PMCID: PMC10158605; DOI: 10.1097/HJH.0000000000003411;

Schmidt IM, Shohet M, Serrano M, Yadati P, Menn-Josephy H, Ilori T, Eneanya ND, Cleveland Manchanda EC, Waikar SS. Patients' Perspectives on Race and the Use of Race-Based Algorithms in Clinical Decision-Making: a Qualitative Study. J Gen Intern Med. 2023 Jul; 38(9):2045-2051.View Related Profiles.

Cleveland Manchanda, Emily
Menn-Josephy, Hanni
Schmidt, Insa
Waikar, Sushrut
Ilori, Titilayo

PMID: 36811702; PMCID: PMC9945816; DOI: 10.1007/s11606-023-08035-4;

Mc Causland FR, Hsu JY, Himmelfarb J, Ikizler TA, Raj DS, Mehrotra R, Waikar SS, Kimmel PL, Kliger AS, Dember LM, Charytan DM. Effects of Spironolactone on Arrhythmias in Hemodialysis Patients: Secondary Results of the SPin-D Randomized Controlled Trial. Kidney360. 2023 Apr 01; 4(4):e486-e495. PMID: 36763641; PMCID: PMC10278797; DOI: 10.34067/KID.0000000000000067;

Ilori TO, Solarin A, Manmak M, Raji YR, Braimoh R, Kwakyi E, Umeizudike T, Ajepe T, Bolanle O, Ripiye N, Eduful E, Adebile T, Ijeoma C, Mumuni AA, Chern J, Akinpelu M, Ulasi I, Arogundade F, Salako BL, Gbadegesin R, Parekh RS, Dupuis J, Amira CO, Adu D, Anderson CAM, Ojo A, Waikar SS. Rationale and Design of the Diet, CKD, and Apolipoprotein L1 Study in Low-Income and Middle-Income Countries. Kidney Int Rep. 2023 Apr; 8(4):764-774.View Related Profiles.

Chern, Jessica
Dupuis, Josee
Waikar, Sushrut
Ilori, Titilayo

PMID: 37069986; PMCID: PMC10105057; DOI: 10.1016/j.ekir.2023.01.019;

Ferkowicz MJ, Winfree S, Sabo AR, Kamocka MM, Khochare S, Barwinska D, Eadon MT, Cheng YH, Phillips CL, Sutton TA, Kelly KJ, Dagher PC, El-Achkar TM, Dunn KW, Knight R, Lecker S, Stillman I, Mcmahon G, Waikar S, Weins A, Hacohen N, Hoover P, Aulisio M, Cooperman L, Herlitz L, O'toole J, Poggio E, Sedor J, Appelbaum P, Barasch J, Bomback A, D'agati V, Kiryluk K, Mehl K, Shang NS, Weng C, Barisoni L, Alexandrov T, Ashkar T, Barwinska D, Dagher P, Dunn K, Eadon M, Ferkowicz M, Kelly K, Sutton T, Winfree S, Menez S, Parikh C, Rosenberg A, Villalobos P, Slack A, Rosas S, Williams M, Azeloglu E, He CJ, Iyengar R, Parikh S, Anderton C, Pasa-Tolic L, Velickovic D, Oliver GH, Ardayfio J, Bebiak J, Brown K, Campbell T, Campbell C, Hayashi L, Jefferson N, Koewler R, Roberts G, Saul J, Shpigel A, Stutzke EC, Wright L, Miegs L, Pinkeney R, Sealfon R, Troyanskaya O, Tuttle K, Goltsev Y, Lake B, Zhang K, Dobi D, Joanes M, Laszik Z, Nolan G, Schroeder A, Balis U, He O, Hodgin J, Kretzler M, Mariani L, Menon R, Otto E, Schaub J, Steck B, Elder M, Hall D, Kellum J, Kruth M, Murugan R, Palevsky P, Randhawa P, Rosengart M, Sims-Lucas S, Stefanick M, Stull S, Tublin M, Alpers C, Boer I, Fullerton M, Himmelfarb J, Mcclelland R, Mooney S, Shankland S, Williams K, Blank K, Dighe A, Carson J, Dowd F, Drager Z, Sharma K, Zhang G, Kermani A, Lee S, Lu C, Miller T, Moe O, Park H, Sambandam K, Sanchez F, Torrealba J, Robert T, Vazquez M, Wang N, Gaut J, Jain S, Vijayan A, Luciano R, Moledina D, Ugochukwu U, Wilson FP. Large-scale, three-dimensional tissue cytometry of the human kidney: a complete and accessible pipeline. Lab Invest. 2021 May; 101(5):661-676. PMID: 36775387

Alostaz M, Correa S, Lundy GS, Waikar SS, Mc Causland FR. Time of hemodialysis and risk of intradialytic hypotension and intradialytic hypertension in maintenance hemodialysis. J Hum Hypertens. 2023 Oct; 37(10):880-890. PMID: 36599899

Singh AT, Yen TE, Mothi SS, Waikar SS, Mc Causland FR. Associations of Iron Sucrose and Intradialytic Blood Pressure. Am J Kidney Dis. 2023 Jun; 81(6):647-654. PMID: 36587889; PMCID: PMC10205679; DOI: 10.1053/j.ajkd.2022.11.007;

Taguchi K, Elias BC, Sugahara S, Sant S, Freedman BS, Waikar SS, Pozzi A, Zent R, Harris RC, Parikh SM, Brooks CR. Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation. J Clin Invest. 2022 Dec 01; 132(23). PMID: 36453545; PMCID: PMC9711881; DOI: 10.1172/JCI158096;

Liu J, Nair V, Zhao YY, Chang DY, Limonte C, Bansal N, Fermin D, Eichinger F, Tanner EC, Bellovich KA, Steigerwalt S, Bhat Z, Hawkins JJ, Subramanian L, Rosas SE, Sedor JR, Vasquez MA, Waikar SS, Bitzer M, Pennathur S, Brosius FC, De Boer I, Chen M, Kretzler M, Ju W. Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease. Diabetes. 2022 Dec 01; 71(12):2664-2676. PMID: 36331122; PMCID: PMC9750948; DOI: 10.2337/db22-0169;

Liu J, Bankir L, Verma A, Waikar SS, Palsson R. Association of the Urine-to-Plasma Urea Ratio With CKD Progression. Am J Kidney Dis. 2023 Apr; 81(4):394-405.View Related Profiles.

Verma, Ashish
Waikar, Sushrut

PMID: 36356680; DOI: 10.1053/j.ajkd.2022.09.010;

Ermer T, Nazzal L, Tio MC, Waikar S, Aronson PS, Knauf F. Oxalate homeostasis. Nat Rev Nephrol. 2023 Feb; 19(2):123-138. PMID: 36329260; PMCID: PMC10278040; DOI: 10.1038/s41581-022-00643-3;

Wen D, Zhou L, Zheng Z, Surapaneni A, Ballantyne CM, Hoogeveen RC, Shlipak MG, Waikar SS, Vasan RS, Kimmel PL, Dubin RF, Deo R, Feldman HI, Ganz P, Coresh J, Grams ME, Rhee EP. Testican-2 Is Associated with Reduced Risk of Incident ESKD. J Am Soc Nephrol. 2023 Jan 01; 34(1):122-131. PMID: 36288905; PMCID: PMC10101586; DOI: 10.1681/ASN.2022020216;

Wen D, Zheng Z, Surapaneni A, Yu B, Zhou L, Zhou W, Xie D, Shou H, Avila-Pacheco J, Kalim S, He J, Hsu CY, Parsa A, Rao P, Sondheimer J, Townsend R, Waikar SS, Rebholz CM, Denburg MR, Kimmel PL, Vasan RS, Clish CB, Coresh J, Feldman HI, Grams ME, Rhee EP. Metabolite profiling of CKD progression in the chronic renal insufficiency cohort study. JCI Insight. 2022 Oct 24; 7(20). PMID: 36048534; PMCID: PMC9714776; DOI: 10.1172/jci.insight.161696;

Perkovic V, Blackorby A, Cizman B, Carroll K, Cobitz AR, Davies R, DiMino TL, Jha V, Johansen KL, Lopes RD, Kler L, Macdougall IC, McMurray JJV, Meadowcroft AM, Obrador GT, Solomon S, Taft L, Wanner C, Waikar SS, Wheeler DC, Wiecek A, Singh AK. The ASCEND-ND trial: study design and participant characteristics. Nephrol Dial Transplant. 2022 Oct 19; 37(11):2157-2170. PMID: 34865143; PMCID: PMC9585467; DOI: 10.1093/ndt/gfab318;

Verma A, Vaidya A, Subudhi S, Waikar SS. Aldosterone in chronic kidney disease and renal outcomes. Eur Heart J. 2022 Oct 11; 43(38):3781-3791.View Related Profiles.

Verma, Ashish
Waikar, Sushrut

PMID: 36219773; PMCID: PMC10147385; DOI: 10.1093/eurheartj/ehac352;

Claudel SE, Waikar SS, Verma A. Severe hyponatremia due to surreptitious water intoxication in a hospitalized patient. CEN Case Rep. 2023 May; 12(2):135-138.View Related Profiles.

Verma, Ashish
Claudel, Sophie
Waikar, Sushrut

PMID: 36107392; PMCID: PMC9476424; DOI: 10.1007/s13730-022-00733-y;

Schmidt IM, Myrick S, Liu J, Verma A, Srivastava A, Palsson R, Onul IF, Stillman IE, Avillach C, Patil P, Waikar SS. The use of plasma biomarker-derived clusters for clinicopathologic phenotyping: results from the Boston Kidney Biopsy Cohort. Clin Kidney J. 2023 Jan; 16(1):90-99.View Related Profiles.

Verma, Ashish
Avillach, Claire
Schmidt, Insa
Patil, Prasad
Waikar, Sushrut

PMID: 36726432; PMCID: PMC9871860; DOI: 10.1093/ckj/sfac202;

Wilson PC, Muto Y, Wu H, Karihaloo A, Waikar SS, Humphreys BD. Multimodal single cell sequencing implicates chromatin accessibility and genetic background in diabetic kidney disease progression. Nat Commun. 2022 Sep 06; 13(1):5253. PMID: 36068241; PMCID: PMC9448792; DOI: 10.1038/s41467-022-32972-z;

Ilori TO, Liu J, Rodan AR, Verma A, Mills KT, He J, Winkler CA, Dupuis J, Anderson CAM, Waikar SS. Apolipoprotein L1 Genotypes and the Association of Urinary Potassium Excretion with CKD Progression. Clin J Am Soc Nephrol. 2022 Oct; 17(10):1477-1486.View Related Profiles.

Verma, Ashish
Dupuis, Josee
Waikar, Sushrut
Ilori, Titilayo

PMID: 36400568; PMCID: PMC9528272; DOI: 10.2215/CJN.02680322;

Causland FRM, Ravi KS, Curtis KA, Kibbelaar ZA, Short SAP, Singh AT, Correa S, Waikar SS. A randomized controlled trial of two dialysate sodium concentrations in hospitalized hemodialysis patients. Nephrol Dial Transplant. 2022 Jun 23; 37(7):1340-1347. PMID: 34792161; PMCID: PMC9217525; DOI: 10.1093/ndt/gfab329;

Limonte CP, Valo E, Drel V, Natarajan L, Darshi M, Forsblom C, Henderson CM, Hoofnagle AN, Ju W, Kretzler M, Montemayor D, Nair V, Nelson RG, O'Toole JF, Toto RD, Rosas SE, Ruzinski J, Sandholm N, Schmidt IM, Vaisar T, Waikar SS, Zhang J, Rossing P, Ahluwalia TS, Groop PH, Pennathur S, Snell-Bergeon JK, Costacou T, Orchard TJ, Sharma K, de Boer IH. Urinary Proteomics Identifies Cathepsin D as a Biomarker of Rapid eGFR Decline in Type 1 Diabetes. Diabetes Care. 2022 Jun 02; 45(6):1416-1427.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut

PMID: 35377940; PMCID: PMC9210873; DOI: 10.2337/dc21-2204;

Schmidt IM, Colona MR, Srivastava A, Yu G, Sabbisetti V, Bonventre JV, Waikar SS. Plasma Kidney Injury Molecule-1 in Systemic Lupus Erythematosus: Discordance Between ELISA and Proximity Extension Assay. Kidney Med. 2022 Aug; 4(8):100496.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut

PMID: 36061370; PMCID: PMC9437607; DOI: 10.1016/j.xkme.2022.100496;

Singh AK, Cizman B, Carroll K, McMurray JJV, Perkovic V, Jha V, Johansen KL, Lopes RD, Macdougall IC, Obrador GT, Waikar SS, Wanner C, Wheeler DC, Wiecek A, Stankus N, Strutz F, Blackorby A, Cobitz AR, Meadowcroft AM, Paul G, Ranganathan P, Sedani S, Solomon S. Efficacy and Safety of Daprodustat for Treatment of Anemia of Chronic Kidney Disease in Incident Dialysis Patients: A Randomized Clinical Trial. JAMA Intern Med. 2022 Jun 01; 182(6):592-602. PMID: 35377393; PMCID: PMC8981070; DOI: 10.1001/jamainternmed.2022.0605;

Correa S, Guerra-Torres XE, Ravi KS, Mothi SS, Waikar SS, Mc Causland FR. Risk of Intradialytic Hypotension by Day of the Week in Maintenance Hemodialysis. ASAIO J. 2022 Jun 01; 68(6):865-873. PMID: 34494985; PMCID: PMC10157838; DOI: 10.1097/MAT.0000000000001576;

Samal L, D'Amore JD, Gannon MP, Kilgallon JL, Charles JP, Mann DM, Siegel LC, Burdge K, Shaykevich S, Lipsitz S, Waikar SS, Bates DW, Wright A. Impact of Kidney Failure Risk Prediction Clinical Decision Support on Monitoring and Referral in Primary Care Management of CKD: A Randomized Pragmatic Clinical Trial. Kidney Med. 2022 Jul; 4(7):100493. PMID: 35866010; PMCID: PMC9293940; DOI: 10.1016/j.xkme.2022.100493;

Singh AK, Blackorby A, Cizman B, Carroll K, Cobitz AR, Davies R, Jha V, Johansen KL, Lopes RD, Kler L, Macdougall IC, McMurray JJV, Meadowcroft AM, Obrador GT, Perkovic V, Solomon S, Wanner C, Waikar SS, Wheeler DC, Wiecek A. Study design and baseline characteristics of patients on dialysis in the ASCEND-D trial. Nephrol Dial Transplant. 2022 Apr 25; 37(5):960-972. PMID: 33744933; PMCID: PMC9035347; DOI: 10.1093/ndt/gfab065;

Eneanya ND, Lakin JR, Paasche-Orlow MK, Lindvall C, Moseley ET, Henault L, Hanchate AD, Mandel EI, Wong SPY, Zupanc SN, Davis AD, El-Jawahri A, Quintiliani LM, Chang Y, Waikar SS, Bansal AD, Schell JO, Lundquist AL, Tamura MK, Yu MK, Unruh ML, Argyropoulos C, Germain MJ, Volandes A. Video Images about Decisions for Ethical Outcomes in Kidney Disease (VIDEO-KD): the study protocol for a multi-centre randomised controlled trial. BMJ Open. 2022 Apr 08; 12(4):e059313.View Related Profiles.

Hanchate, Amresh
Quintiliani, Lisa
Paasche-Orlow, Michael
Waikar, Sushrut

PMID: 35396311; PMCID: PMC8996022; DOI: 10.1136/bmjopen-2021-059313;

Amatruda JG, Katz R, Sarnak MJ, Gutierrez OM, Greenberg JH, Cushman M, Waikar S, Parikh CR, Schelling JR, Jogalekar MP, Bonventre JV, Vasan RS, Kimmel PL, Shlipak MG, Ix JH. Biomarkers of Kidney Tubule Disease and Risk of End-Stage Kidney Disease in Persons With Diabetes and CKD. Kidney Int Rep. 2022 Jul; 7(7):1514-1523. PMID: 35812302; PMCID: PMC9263389; DOI: 10.1016/j.ekir.2022.03.033;

Sarnak MJ, Katz R, Ix JH, Kimmel PL, Bonventre JV, Schelling J, Cushman M, Vasan RS, Waikar SS, Greenberg JH, Parikh CR, Coca SG, Sabbisetti V, Jogalekar MP, Rebholz C, Zheng Z, Gutierrez OM, Shlipak MG. Plasma Biomarkers as Risk Factors for Incident CKD. Kidney Int Rep. 2022 Jul; 7(7):1493-1501. PMID: 35812266; PMCID: PMC9263237; DOI: 10.1016/j.ekir.2022.03.018;

Johnson MJ, Tommerdahl KL, Vinovskis C, Waikar S, Reinicke T, Parikh CR, Obeid W, Nelson RG, van Raalte DH, Pyle L, Nadeau KJ, Bjornstad P. Relationship between biomarkers of tubular injury and intrarenal hemodynamic dysfunction in youth with type 1 diabetes. Pediatr Nephrol. 2022 Dec; 37(12):3085-3092. PMID: 35286453; PMCID: PMC9470783; DOI: 10.1007/s00467-022-05487-4;

Singh AT, Waikar SS, Mc Causland FR. Association of Different Definitions of Intradialytic Hypertension With Long-Term Mortality in Hemodialysis. Hypertension. 2022 04; 79(4):855-862. PMID: 35166122; PMCID: PMC8916991; DOI: 10.1161/HYPERTENSIONAHA.121.18058;

Rhee EP, Surapaneni A, Zheng Z, Zhou L, Dutta D, Arking DE, Zhang J, Duong T, Chatterjee N, Luo S, Schlosser P, Mehta R, Waikar SS, Saraf SL, Kelly TN, Hamm LL, Rao PS, Mathew AV, Hsu CY, Parsa A, Vasan RS, Kimmel PL, Clish CB, Coresh J, Feldman HI, Grams ME. Trans-ethnic genome-wide association study of blood metabolites in the Chronic Renal Insufficiency Cohort (CRIC) study. Kidney Int. 2022 04; 101(4):814-823. PMID: 35120996; PMCID: PMC8940669; DOI: 10.1016/j.kint.2022.01.014;

Adler JT, Husain SA, Xiang L, Rodrigue JR, Waikar SS. Initial Home Dialysis Is Increased for Rural Patients by Accessing Urban Facilities. Kidney360. 2022 Mar 31; 3(3):488-496. PMID: 35582180; PMCID: PMC9034801; DOI: 10.34067/KID.0006932021;

Liu J, Tio MC, Verma A, Schmidt IM, Ilori TO, Knauf F, Mc Causland FR, Waikar SS. Determinants and Outcomes Associated With Urinary Calcium Excretion in Chronic Kidney Disease. J Clin Endocrinol Metab. 2022 01 01; 107(1):e281-e292.View Related Profiles.

Verma, Ashish
Schmidt, Insa
Waikar, Sushrut
Ilori, Titilayo

PMID: 34390334; PMCID: PMC8684460; DOI: 10.1210/clinem/dgab574;

Koopman JJE, Rennke HG, McMahon GM, Waikar SS, Costenbader KH. Associations between renal deposits of complement factors, disease activity and loss of renal function in lupus nephritis. J Clin Pathol. 2022 11; 75(11):789-790. PMID: 34969783; PMCID: PMC10015506; DOI: 10.1136/jclinpath-2021-207788;

Kilgallon JL, Gannon M, Burns Z, McMahon G, Dykes P, Linder J, Bates DW, Waikar S, Lipsitz S, Baer HJ, Samal L. Multicomponent intervention to improve blood pressure management in chronic kidney disease: a protocol for a pragmatic clinical trial. BMJ Open. 2021 12 22; 11(12):e054065. PMID: 34937722; PMCID: PMC8705218; DOI: 10.1136/bmjopen-2021-054065;

Kelly YP, Mistry K, Ahmed S, Shaykevich S, Desai S, Lipsitz SR, Leaf DE, Mandel EI, Robinson E, McMahon G, Czarnecki PG, Charytan DM, Waikar SS, Mendu ML. Controlled Study of Decision-Making Algorithms for Kidney Replacement Therapy Initiation in Acute Kidney Injury. Clin J Am Soc Nephrol. 2022 02; 17(2):194-204. PMID: 34911731; PMCID: PMC8823944; DOI: 10.2215/CJN.02060221;

Butler CR, Appelbaum PS, Ascani H, Aulisio M, Campbell CE, de Boer IH, Dighe AL, Hall DE, Himmelfarb J, Knight R, Mehl K, Murugan R, Rosas SE, Sedor JR, O'Toole JF, Tuttle KR, Waikar SS, Freeman M. A Participant-Centered Approach to Understanding Risks and Benefits of Participation in Research Informed by the Kidney Precision Medicine Project. Am J Kidney Dis. 2022 Jul; 80(1):132-138. PMID: 34871700; PMCID: PMC9166631; DOI: 10.1053/j.ajkd.2021.10.006;

Singh AT, Mothi SS, Li P, Sabbisetti V, Waikar SS, Mc Causland FR. Endothelin-1 and Parameters of Systolic Blood Pressure in Hemodialysis. Am J Hypertens. 2021 Nov 20; 34(11):1203-1208. PMID: 34192305; PMCID: PMC9526807; DOI: 10.1093/ajh/hpab104;

Jain A, Huang R, Lee J, Jawa N, Lim YJ, Guron M, Abish S, Boutros PC, Brudno M, Carleton B, Cuvelier GDE, Gunaratnam L, Ho C, Adeli K, Kuruvilla S, Lajoie G, Liu G, Nathan PC, Rod Rassekh S, Rieder M, Waikar SS, Welch SA, Weir MA, Winquist E, Wishart DS, Zorzi AP, Blydt-Hansen T, Zappitelli M, Urquhart B. A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol. Can J Kidney Health Dis. 2021; 8:20543581211057708. PMID: 34820133; PMCID: PMC8606978; DOI: 10.1177/20543581211057708;

Schmidt IM, Sarvode Mothi S, Wilson PC, Palsson R, Srivastava A, Onul IF, Kibbelaar ZA, Zhuo M, Amodu A, Stillman IE, Rennke HG, Humphreys BD, Waikar SS. Circulating Plasma Biomarkers in Biopsy-Confirmed Kidney Disease. Clin J Am Soc Nephrol. 2022 01; 17(1):27-37.View Related Profiles.

Amodu, Afolarin
Schmidt, Insa
Waikar, Sushrut

PMID: 34759008; PMCID: PMC8763150; DOI: 10.2215/CJN.09380721;

Gutiérrez OM, Shlipak MG, Katz R, Waikar SS, Greenberg JH, Schrauben SJ, Coca S, Parikh CR, Vasan RS, Feldman HI, Kimmel PL, Cushman M, Bonventre JV, Sarnak MJ, Ix JH. Associations of Plasma Biomarkers of Inflammation, Fibrosis, and Kidney Tubular Injury With Progression of Diabetic Kidney Disease: A Cohort Study. Am J Kidney Dis. 2022 Jun; 79(6):849-857.e1. PMID: 34752914; PMCID: PMC9072594; DOI: 10.1053/j.ajkd.2021.09.018;

Singh AK, Carroll K, Perkovic V, Solomon S, Jha V, Johansen KL, Lopes RD, Macdougall IC, Obrador GT, Waikar SS, Wanner C, Wheeler DC, Wiecek A, Blackorby A, Cizman B, Cobitz AR, Davies R, Dole J, Kler L, Meadowcroft AM, Zhu X, McMurray JJV. Daprodustat for the Treatment of Anemia in Patients Undergoing Dialysis. N Engl J Med. 2021 12 16; 385(25):2325-2335. PMID: 34739194

Singh AK, Carroll K, McMurray JJV, Solomon S, Jha V, Johansen KL, Lopes RD, Macdougall IC, Obrador GT, Waikar SS, Wanner C, Wheeler DC, Wiecek A, Blackorby A, Cizman B, Cobitz AR, Davies R, DiMino TL, Kler L, Meadowcroft AM, Taft L, Perkovic V. Daprodustat for the Treatment of Anemia in Patients Not Undergoing Dialysis. N Engl J Med. 2021 12 16; 385(25):2313-2324. PMID: 34739196

Watts AJB, Keller KH, Lerner G, Rosales I, Collins AB, Sekulic M, Waikar SS, Chandraker A, Riella LV, Alexander MP, Troost JP, Chen J, Fermin D, Yee JL, Sampson MG, Beck LH, Henderson JM, Greka A, Rennke HG, Weins A. Discovery of Autoantibodies Targeting Nephrin in Minimal Change Disease Supports a Novel Autoimmune Etiology. J Am Soc Nephrol. 2022 01; 33(1):238-252.View Related Profiles.

Henderson, Joel
Beck, Laurence
Waikar, Sushrut

PMID: 34732507; PMCID: PMC8763186; DOI: 10.1681/ASN.2021060794;

Correa S, Guerra-Torres XE, Waikar SS, Mc Causland FR. Serum Magnesium, Blood Pressure, and Risk of Hypertension and Chronic Kidney Disease Progression in the CRIC Study. Hypertension. 2021 12; 78(6):1771-1780. PMID: 34757763

Raundhal M, Ghosh S, Myers SA, Cuoco MS, Singer M, Carr SA, Waikar SS, Bonventre JV, Ritz J, Stone RM, Steensma DP, Regev A, Glimcher LH. Author Correction: Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias. Nat Immunol. 2021 Nov; 22(11):1465. PMID: 34522041

Garimella PS, Katz R, Waikar SS, Srivastava A, Schmidt I, Hoofnagle A, Palsson R, Rennke HG, Stillman IE, Wang K, Kestenbaum BR, Ix JH. Kidney Tubulointerstitial Fibrosis and Tubular Secretion. Am J Kidney Dis. 2022 May; 79(5):709-716.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut

PMID: 34571064; PMCID: PMC8973399; DOI: 10.1053/j.ajkd.2021.08.015;

Hsu CY, Yang W, Parikh RV, Anderson AH, Chen TK, Cohen DL, He J, Mohanty MJ, Lash JP, Mills KT, Muiru AN, Parsa A, Saunders MR, Shafi T, Townsend RR, Waikar SS, Wang J, Wolf M, Tan TC, Feldman HI, Go AS. Race, Genetic Ancestry, and Estimating Kidney Function in CKD. N Engl J Med. 2021 11 04; 385(19):1750-1760. PMID: 34554660; PMCID: PMC8994696; DOI: 10.1056/NEJMoa2103753;

Amodu A, Porteny T, Schmidt IM, Ladin K, Waikar SS. Nephrologists' Attitudes Toward Native Kidney Biopsy: A Qualitative Study. Kidney Med. 2021 Nov-Dec; 3(6):1022-1031.View Related Profiles.

Amodu, Afolarin
Schmidt, Insa
Waikar, Sushrut

PMID: 34939011; PMCID: PMC8664729; DOI: 10.1016/j.xkme.2021.06.014;

Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Ix JH, Jogalekar MP, Coca S, Waikar SS, Shlipak MG, Warady BA, Vasan RS, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S. Urine Biomarkers of Kidney Tubule Health, Injury, and Inflammation are Associated with Progression of CKD in Children. J Am Soc Nephrol. 2021 10; 32(10):2664-2677. PMID: 34544821; PMCID: PMC8722795; DOI: 10.1681/ASN.2021010094;

Schwarzschild MA, Ascherio A, Casaceli C, Curhan GC, Fitzgerald R, Kamp C, Lungu C, Macklin EA, Marek K, Mozaffarian D, Oakes D, Rudolph A, Shoulson I, Videnovic A, Scott B, Gauger L, Aldred J, Bixby M, Ciccarello J, Gunzler SA, Henchcliffe C, Brodsky M, Keith K, Hauser RA, Goetz C, LeDoux MS, Hinson V, Kumar R, Espay AJ, Jimenez-Shahed J, Hunter C, Christine C, Daley A, Leehey M, de Marcaida JA, Friedman JH, Hung A, Bwala G, Litvan I, Simon DK, Simuni T, Poon C, Schiess MC, Chou K, Park A, Bhatti D, Peterson C, Criswell SR, Rosenthal L, Durphy J, Shill HA, Mehta SH, Ahmed A, Deik AF, Fang JY, Stover N, Zhang L, Dewey RB, Gerald A, Boyd JT, Houston E, Suski V, Mosovsky S, Cloud L, Shah BB, Saint-Hilaire M, James R, Zauber SE, Reich S, Shprecher D, Pahwa R, Langhammer A, LaFaver K, LeWitt PA, Kaminski P, Goudreau J, Russell D, Houghton DJ, Laroche A, Thomas K, McGraw M, Mari Z, Serrano C, Blindauer K, Rabin M, Kurlan R, Morgan JC, Soileau M, Ainslie M, Bodis-Wollner I, Schneider RB, Waters C, Ratel AS, Beck CA, Bolger P, Callahan KF, Crotty GF, Klements D, Kostrzebski M, McMahon GM, Pothier L, Waikar SS, Lang A, Mestre T. Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial. JAMA. 2021 09 14; 326(10):926-939.View Related Profiles.

Saint-Hilaire, Marie-Helene
Waikar, Sushrut

PMID: 34519802; PMCID: PMC8441591; DOI: 10.1001/jama.2021.10207;

Adler JT, Xiang L, Weissman JS, Rodrigue JR, Patzer RE, Waikar SS, Tsai TC. Association of Public Reporting of Medicare Dialysis Facility Quality Ratings With Access to Kidney Transplantation. JAMA Netw Open. 2021 09 01; 4(9):e2126719. PMID: 34559227; PMCID: PMC8463939; DOI: 10.1001/jamanetworkopen.2021.26719;

Pfau A, Ermer T, Coca SG, Tio MC, Genser B, Reichel M, Finkelstein FO, März W, Wanner C, Waikar SS, Eckardt KU, Aronson PS, Drechsler C, Knauf F. High Oxalate Concentrations Correlate with Increased Risk for Sudden Cardiac Death in Dialysis Patients. J Am Soc Nephrol. 2021 09; 32(9):2375-2385. PMID: 34281958; PMCID: PMC8729829; DOI: 10.1681/ASN.2020121793;

Kelly YP, Sharma S, Mothi SS, McCausland FR, Mendu ML, McMahon GM, Palevsky PM, Waikar SS. Hypocalcemia is associated with hypotension during CRRT: A secondary analysis of the Acute Renal Failure Trial Network Study. J Crit Care. 2021 10; 65:261-267. PMID: 34274834

Ravi KS, Reeves PB, Correa S, Neves JS, Waikar SS, Mothi SS, Mc Causland FR. Predialysis serum phosphate and intradialytic hypotension. Hemodial Int. 2022 01; 26(1):38-47. PMID: 34236130

Verma A, Chitalia VC, Waikar SS, Kolachalama VB. Machine Learning Applications in Nephrology: A Bibliometric Analysis Comparing Kidney Studies to Other Medicine Subspecialities. Kidney Med. 2021 Sep-Oct; 3(5):762-767.View Related Profiles.

Verma, Ashish
Waikar, Sushrut
Kolachalama, Vijaya
Chitalia, Vipul

PMID: 34693256; PMCID: PMC8515072; DOI: 10.1016/j.xkme.2021.04.012;

Schmidt IM, Srivastava A, Sabbisetti V, McMahon GM, He J, Chen J, Kusek JW, Taliercio J, Ricardo AC, Hsu CY, Kimmel PL, Liu KD, Mifflin TE, Nelson RG, Vasan RS, Xie D, Zhang X, Palsson R, Stillman IE, Rennke HG, Feldman HI, Bonventre JV, Waikar SS. Plasma Kidney Injury Molecule 1 in CKD: Findings From the Boston Kidney Biopsy Cohort and CRIC Studies. Am J Kidney Dis. 2022 02; 79(2):231-243.e1.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut
Ramachandran, Vasan

PMID: 34175376; PMCID: PMC8709877; DOI: 10.1053/j.ajkd.2021.05.013;

Gannon MP, Wu E, McMahon GM, Aaron S, Bates DW, Waikar S, Samal L. Uncontrolled blood pressure and treatment of hypertension in older chronic kidney disease patients. J Am Geriatr Soc. 2021 10; 69(10):2985-2987. PMID: 34089261; PMCID: PMC8497406; DOI: 10.1111/jgs.17304;

Kamel MH, Mahmoud H, Zhen A, Liu J, Bielick CG, Mostaghim A, Lin N, Chitalia V, Ilori T, Waikar SS, Upadhyay A. End-stage kidney disease and COVID-19 in an urban safety-net hospital in Boston, Massachusetts. PLoS One. 2021; 16(6):e0252679.View Related Profiles.

Zhen, Aileen
Upadhyay, Ashish
Bielick, Catherine
Kamel, Mohamed
Lin, Nina
Waikar, Sushrut
Ilori, Titilayo
Chitalia, Vipul

PMID: 34086775; PMCID: PMC8177422; DOI: 10.1371/journal.pone.0252679;

Schmidt IM, Colona MR, Kestenbaum BR, Alexopoulos LG, Palsson R, Srivastava A, Liu J, Stillman IE, Rennke HG, Vaidya VS, Wu H, Humphreys BD, Waikar SS. Cadherin-11, Sparc-related modular calcium binding protein-2, and Pigment epithelium-derived factor are promising non-invasive biomarkers of kidney fibrosis. Kidney Int. 2021 09; 100(3):672-683.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut

PMID: 34051265; PMCID: PMC8384690; DOI: 10.1016/j.kint.2021.04.037;

Zheng Y, Cassol CA, Jung S, Veerapaneni D, Chitalia VC, Ren KYM, Bellur SS, Boor P, Barisoni LM, Waikar SS, Betke M, Kolachalama VB. Deep-Learning-Driven Quantification of Interstitial Fibrosis in Digitized Kidney Biopsies. Am J Pathol. 2021 08; 191(8):1442-1453.View Related Profiles.

Waikar, Sushrut
Kolachalama, Vijaya
Chitalia, Vipul

PMID: 34033750; PMCID: PMC8453248; DOI: 10.1016/j.ajpath.2021.05.005;

Scovner KM, Correa S, Claggett BL, Barrett CD, Waikar SS, Solomon SD, Mc Causland FR. Specific Electrocardiograph Intervals Predict Hospitalization with Atrial Fibrillation in Those with Chronic Kidney Disease. Am J Nephrol. 2021; 52(5):412-419. PMID: 33951623; PMCID: PMC8263478; DOI: 10.1159/000515670;

Wettersten N, Katz R, Shlipak MG, Scherzer R, Waikar SS, Ix JH, Estrella MM. Urinary Biomarkers and Kidney Outcomes: Impact of Indexing Versus Adjusting for Urinary Creatinine. Kidney Med. 2021 Jul-Aug; 3(4):546-554.e1. PMID: 34401722; PMCID: PMC8350828; DOI: 10.1016/j.xkme.2021.02.013;

Correa S, Curtis KA, Waikar SS, Mc Causland FR. Serum Myeloperoxidase, Uric Acid, and the Risk of Atrial Fibrillation in Chronic Kidney Disease. Circ Arrhythm Electrophysiol. 2021 04; 14(4):e009483. PMID: 33858180

Muto Y, Wilson PC, Ledru N, Wu H, Dimke H, Waikar SS, Humphreys BD. Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney. Nat Commun. 2021 04 13; 12(1):2190. PMID: 33850129; PMCID: PMC8044133; DOI: 10.1038/s41467-021-22368-w;

Srivastava A, Cai X, Mehta R, Lee J, Chu DI, Mills KT, Shafi T, Taliercio JJ, Hsu JY, Schrauben SJ, Saunders MR, Diamantidis CJ, Hsu CY, Waikar SS, Lash JP, Isakova T. Hospitalization Trajectories and Risks of ESKD and Death in Individuals With CKD. Kidney Int Rep. 2021 Jun; 6(6):1592-1602. PMID: 34169199; PMCID: PMC8207467; DOI: 10.1016/j.ekir.2021.03.883;

Raundhal M, Ghosh S, Myers SA, Cuoco MS, Singer M, Carr SA, Waikar SS, Bonventre JV, Ritz J, Stone RM, Steensma DP, Regev A, Glimcher LH. Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias. Nat Immunol. 2021 04; 22(4):520-529. PMID: 33753942; PMCID: PMC8026551; DOI: 10.1038/s41590-021-00895-4;

de Boer IH, Alpers CE, Azeloglu EU, Balis UGJ, Barasch JM, Barisoni L, Blank KN, Bomback AS, Brown K, Dagher PC, Dighe AL, Eadon MT, El-Achkar TM, Gaut JP, Hacohen N, He Y, Hodgin JB, Jain S, Kellum JA, Kiryluk K, Knight R, Laszik ZG, Lienczewski C, Mariani LH, McClelland RL, Menez S, Moledina DG, Mooney SD, O'Toole JF, Palevsky PM, Parikh CR, Poggio ED, Rosas SE, Rosengart MR, Sarwal MM, Schaub JA, Sedor JR, Sharma K, Steck B, Toto RD, Troyanskaya OG, Tuttle KR, Vazquez MA, Waikar SS, Williams K, Wilson FP, Zhang K, Iyengar R, Kretzler M, Himmelfarb J. Rationale and design of the Kidney Precision Medicine Project. Kidney Int. 2021 03; 99(3):498-510. PMID: 33637194; PMCID: PMC8330551; DOI: 10.1016/j.kint.2020.08.039;

Schmidt IM, Waikar SS. Separate and Unequal: Race-Based Algorithms and Implications for Nephrology. J Am Soc Nephrol. 2021 03; 32(3):529-533.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut

PMID: 33510038; PMCID: PMC7920170; DOI: 10.1681/ASN.2020081175;

Jadhav S, Tripathi S, Chandrekar A, Waikar SS, Hsiao LL. A novel antibody for the detection of alternatively spliced secreted KLOTHO isoform in human plasma. PLoS One. 2021; 16(1):e0245614. PMID: 33481901; PMCID: PMC7822350; DOI: 10.1371/journal.pone.0245614;

Zheng Z, Waikar SS, Schmidt IM, Landis JR, Hsu CY, Shafi T, Feldman HI, Anderson AH, Wilson FP, Chen J, Rincon-Choles H, Ricardo AC, Saab G, Isakova T, Kallem R, Fink JC, Rao PS, Xie D, Yang W. Subtyping CKD Patients by Consensus Clustering: The Chronic Renal Insufficiency Cohort (CRIC) Study. J Am Soc Nephrol. 2021 03; 32(3):639-653.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut

PMID: 33462081; PMCID: PMC7920178; DOI: 10.1681/ASN.2020030239;

Chen Y, Zelnick LR, Huber MP, Wang K, Bansal N, Hoofnagle AN, Paranji RK, Heckbert SR, Weiss NS, Go AS, Hsu CY, Feldman HI, Waikar SS, Mehta RC, Srivastava A, Seliger SL, Lash JP, Porter AC, Raj DS, Kestenbaum BR. Association Between Kidney Clearance of Secretory Solutes and Cardiovascular Events: The Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2021 08; 78(2):226-235.e1. PMID: 33421453; PMCID: PMC8260620; DOI: 10.1053/j.ajkd.2020.12.005;

Srivastava A, Schmidt IM, Palsson R, Weins A, Bonventre JV, Sabbisetti V, Stillman IE, Rennke HG, Waikar SS. The Associations of Plasma Biomarkers of Inflammation With Histopathologic Lesions, Kidney Disease Progression, and Mortality-The Boston Kidney Biopsy Cohort Study. Kidney Int Rep. 2021 Mar; 6(3):685-694.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut

PMID: 33732983; PMCID: PMC7938082; DOI: 10.1016/j.ekir.2020.12.025;

Feldman CH, Speyer C, Ashby R, L Bermas B, Bhattacharyya S, Chakravarty E, Everett B, Ferucci E, Hersh AO, Marty FM, Merola JF, Ramsey-Goldman R, Rovin BH, Son MB, Tarter L, Waikar S, Yazdany J, Weissman JS, Costenbader KH. Development of a Set of Lupus-Specific, Ambulatory Care-Sensitive, Potentially Preventable Adverse Conditions: A Delphi Consensus Study. Arthritis Care Res (Hoboken). 2021 01; 73(1):146-157. PMID: 31628721; PMCID: PMC7165052; DOI: 10.1002/acr.24095;

Motwani SS, Choueiri TK, Partridge AH, Hu J, Kaymakcalan MD, Waikar SS, Curhan GC. Comparison of Equations To Estimate Glomerular Filtration Rate and Their Impact on Frequency of Cisplatin-associated Acute Kidney Injury. Kidney360. 2021 Feb 25; 2(2):205-214. PMID: 35373014; PMCID: PMC8741004; DOI: 10.34067/KID.0000572020;

Koopman JJE, Rennke HG, Leatherwood C, Speyer CB, D'Silva K, McMahon GM, Waikar SS, Costenbader KH. Renal deposits of complement factors as predictors of end-stage renal disease and death in patients with lupus nephritis. Rheumatology (Oxford). 2020 12 01; 59(12):3751-3758. PMID: 32413140; PMCID: PMC7733722; DOI: 10.1093/rheumatology/keaa174;

Chen Y, Zelnick LR, Wang K, Katz R, Hoofnagle AN, Becker JO, Hsu CY, Go AS, Feldman HI, Mehta RC, Lash JP, Waikar SS, Hamm L, Chen J, Shafi T, Kestenbaum BR. Association of tubular solute clearances with the glomerular filtration rate and complications of chronic kidney disease: the Chronic Renal Insufficiency Cohort study. Nephrol Dial Transplant. 2020 Nov 17; 36(7):1271-81. PMID: 33330914; PMCID: PMC8237987; DOI: 10.1093/ndt/gfaa057;

Hannan M, Ansari S, Meza N, Anderson AH, Srivastava A, Waikar S, Charleston J, Weir MR, Taliercio J, Horwitz E, Saunders MR, Wolfrum K, Feldman HI, Lash JP, Ricardo AC. Risk Factors for CKD Progression: Overview of Findings from the CRIC Study. Clin J Am Soc Nephrol. 2021 04 07; 16(4):648-659. PMID: 33177074; PMCID: PMC8092061; DOI: 10.2215/CJN.07830520;

Schrauben SJ, Shou H, Zhang X, Anderson AH, Bonventre JV, Chen J, Coca S, Furth SL, Greenberg JH, Gutierrez OM, Ix JH, Lash JP, Parikh CR, Rebholz CM, Sabbisetti V, Sarnak MJ, Shlipak MG, Waikar SS, Kimmel PL, Vasan RS, Feldman HI, Schelling JR. Association of Multiple Plasma Biomarker Concentrations with Progression of Prevalent Diabetic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study. J Am Soc Nephrol. 2021 01; 32(1):115-126. PMID: 33122288; PMCID: PMC7894671; DOI: 10.1681/ASN.2020040487;

Li P, Gupta S, Mothi SS, Rennke HG, Leaf DE, Waikar SS, McMahon GM. Histopathologic Correlates of Kidney Function: Insights From Nephrectomy Specimens. Am J Kidney Dis. 2021 03; 77(3):336-345. PMID: 33098926

Charytan DM, Hsu JY, Mc Causland FR, Waikar SS, Ikizler TA, Raj DS, Landis JR, Mehrotra R, Williams M, DiCarli M, Skali H, Kimmel PL, Kliger AS, Dember LM. Combination Hydralazine and Isosorbide Dinitrate in Dialysis-Dependent ESRD (HIDE): A Randomized, Placebo-Controlled, Pilot Trial. Kidney360. 2020 Dec 31; 1(12):1380-1389. PMID: 35372900; PMCID: PMC8815530; DOI: 10.34067/KID.0004342020;

Verma A, Patel AB, Tio MC, Waikar SS. Caring for Dialysis Patients in a Time of COVID-19. Kidney Med. 2020 Oct 14; 2(6):787-92.View Related Profiles.

Verma, Ashish
Waikar, Sushrut

PMID: 33073227; PMCID: PMC7553995; DOI: 10.1016/j.xkme.2020.07.006;

Nuzzo PV, Berchuck JE, Korthauer K, Spisak S, Nassar AH, Alaiwi SA, Chakravarthy A, Shen SY, Bakouny Z, Boccardo F, Steinharter J, Bouchard G, Curran CR, Pan W, Baca SC, Seo JH, Lee GM, Michaelson MD, Chang SL, Waikar SS, Sonpavde G, Irizarry RA, Pomerantz M, De Carvalho DD, Choueiri TK, Freedman ML. Author Correction: Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nat Med. 2020 Oct; 26(10):1663. PMID: 32895574

Gupta S, Tio MC, Gutowski ED, Stecker MS, Verma A, Motwani SS, Mount DB, McMahon GM, Waikar SS. Incidence of Hyponatremia in Patients With Indwelling Peritoneal Catheters for Drainage of Malignant Ascites. JAMA Netw Open. 2020 10 01; 3(10):e2017859.View Related Profiles.

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Mount, David Bruce
Waikar, Sushrut

PMID: 33104204; PMCID: PMC7588930; DOI: 10.1001/jamanetworkopen.2020.17859;

Liu CK, Ghai S, Waikar SS, Weiner DE. COVID-19 Infection Risk Among Hemodialysis Patients in Long-term Care Facilities. Kidney Med. 2020 Nov-Dec; 2(6):810-811.View Related Profiles.

Ghai, Sandeep
Waikar, Sushrut

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Ong E, Wang LL, Schaub J, O'Toole JF, Steck B, Rosenberg AZ, Dowd F, Hansen J, Barisoni L, Jain S, de Boer IH, Valerius MT, Waikar SS, Park C, Crawford DC, Alexandrov T, Anderton CR, Stoeckert C, Weng C, Diehl AD, Mungall CJ, Haendel M, Robinson PN, Himmelfarb J, Iyengar R, Kretzler M, Mooney S, He Y. Modelling kidney disease using ontology: insights from the Kidney Precision Medicine Project. Nat Rev Nephrol. 2020 11; 16(11):686-696. PMID: 32939051; PMCID: PMC8012202; DOI: 10.1038/s41581-020-00335-w;

Koopman JJE, Scherzer R, Ix JH, Shlipak MG, Waikar SS. A Comparison of Different Estimates of Albuminuria in Association with Mortality in Epidemiologic Research. Clin J Am Soc Nephrol. 2020 12 07; 15(12):1814-1816. PMID: 32928745; PMCID: PMC7769031; DOI: 10.2215/CJN.07290520;

Bargagli M, Tio MC, Waikar SS, Ferraro PM. Dietary Oxalate Intake and Kidney Outcomes. Nutrients. 2020 Sep 02; 12(9). PMID: 32887293; PMCID: PMC7551439; DOI: 10.3390/nu12092673;

Burns RB, Waikar SS, Wachterman MW, Kanjee Z. Management Options for an Older Adult With Advanced Chronic Kidney Disease and Dementia: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2020 08 04; 173(3):217-225.View Related Profiles.

Wachterman, Melissa
Waikar, Sushrut

PMID: 32745449

Palsson R, Colona MR, Hoenig MP, Lundquist AL, Novak JE, Perazella MA, Waikar SS. Assessment of Interobserver Reliability of Nephrologist Examination of Urine Sediment. JAMA Netw Open. 2020 08 03; 3(8):e2013959. PMID: 32821922; PMCID: PMC7442930; DOI: 10.1001/jamanetworkopen.2020.13959;

Verma A, Patel AB, Waikar SS. SGLT2 Inhibitor: Not a Traditional Diuretic for Heart Failure. Cell Metab. 2020 07 07; 32(1):13-14.View Related Profiles.

Verma, Ashish
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PMID: 32640243

Schmidt IM, Verma A, Waikar SS. Circulating plasma angiotensin-converting enzyme 2 concentrations in patients with kidney disease. Eur Heart J. 2020 07 01; 41(32):3097-3098.View Related Profiles.

Verma, Ashish
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Waikar, Sushrut

PMID: 32691065; PMCID: PMC7470752; DOI: 10.1093/eurheartj/ehaa523;

Ayus JC, Fuentes N, Go AS, Achinger SG, Moritz ML, Nigwekar SU, Waikar SS, Negri AL. Chronicity of Uncorrected Hyponatremia and Clinical Outcomes in Older Patients Undergoing Hip Fracture Repair. Front Med (Lausanne). 2020; 7:263. PMID: 32695787; PMCID: PMC7338672; DOI: 10.3389/fmed.2020.00263;

Nuzzo PV, Berchuck JE, Korthauer K, Spisak S, Nassar AH, Abou Alaiwi S, Chakravarthy A, Shen SY, Bakouny Z, Boccardo F, Steinharter J, Bouchard G, Curran CR, Pan W, Baca SC, Seo JH, Lee GM, Michaelson MD, Chang SL, Waikar SS, Sonpavde G, Irizarry RA, Pomerantz M, De Carvalho DD, Choueiri TK, Freedman ML. Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes. Nat Med. 2020 07; 26(7):1041-1043. PMID: 32572266; PMCID: PMC8288043; DOI: 10.1038/s41591-020-0933-1;

Sise ME, Strohbehn I, Chute D, Corey KE, Fusco DN, Sabbisetti VS, Waikar SS, Chung RT. Low Complement C4 Predicts Improvement of Kidney Function After Direct-Acting Antiviral Therapy for Hepatitis C Virus. Hepatol Commun. 2020 Aug; 4(8):1206-1217. PMID: 32766479; PMCID: PMC7395066; DOI: 10.1002/hep4.1528;

Stern LD, Waikar S. Time to Expand Access and Utilization of Home Dialysis: Lessons From the COVID-19 Pandemic. Mayo Clin Proc. 2020 07; 95(7):1323-1324.View Related Profiles.

Stern, Lauren
Waikar, Sushrut

PMID: 32622441; PMCID: PMC7264034; DOI: 10.1016/j.mayocp.2020.04.038;

Hod T, Freedberg KJ, Motwani SS, Chen M, Frendl G, Leaf DE, Gupta S, Mothi SS, Richards WG, Bueno R, Waikar SS. Acute kidney injury after cytoreductive surgery and hyperthermic intraoperative cisplatin chemotherapy for malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 2021 Apr; 161(4):1510-1518. PMID: 32631662

Sharma S, Kelly YP, Palevsky PM, Waikar SS. Intensity of Renal Replacement Therapy and Duration of Mechanical Ventilation: Secondary Analysis of the Acute Renal Failure Trial Network Study. Chest. 2020 10; 158(4):1473-1481. PMID: 32470389; PMCID: PMC8173776; DOI: 10.1016/j.chest.2020.05.542;

Li P, Schmidt IM, Sabbisetti V, Tio MC, Opotowsky AR, Waikar SS. Plasma Endothelin-1 and Risk of Death and Hospitalization in Patients Undergoing Maintenance Hemodialysis. Clin J Am Soc Nephrol. 2020 06 08; 15(6):784-793.View Related Profiles.

Schmidt, Insa
Waikar, Sushrut

PMID: 32381583; PMCID: PMC7274287; DOI: 10.2215/CJN.11130919;

Kwan B, Fuhrer T, Zhang J, Darshi M, Van Espen B, Montemayor D, de Boer IH, Dobre M, Hsu CY, Kelly TN, Raj DS, Rao PS, Saraf SL, Scialla J, Waikar SS, Sharma K, Natarajan L. Metabolomic Markers of Kidney Function Decline in Patients With Diabetes: Evidence From the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 10; 76(4):511-520. PMID: 32387023; PMCID: PMC7529642; DOI: 10.1053/j.ajkd.2020.01.019;

Palsson R, Chandraker AK, Curhan GC, Rennke HG, McMahon GM, Waikar SS. The association of calcium oxalate deposition in kidney allografts with graft and patient survival. Nephrol Dial Transplant. 2020 05 01; 35(5):888-894. PMID: 30165691; PMCID: PMC7849934; DOI: 10.1093/ndt/gfy271;

Hudson JI, Kanayama G, Pope HG, Muse S, Kaufman MJ, Baggish A, Waikar SS. Glomerular Filtration Rate and Supraphysiologic-Dose Anabolic-Androgenic Steroid Use: A Cross-sectional Cohort Study. Am J Kidney Dis. 2020 07; 76(1):152-155. PMID: 32362416; PMCID: PMC7744117; DOI: 10.1053/j.ajkd.2020.01.012;

Verma A, Patel AB, Upadhyay A, Waikar SS. CREDENCE: Significant Victory for Diabetic Kidney Disease. Trends Endocrinol Metab. 2020 06; 31(6):391-393.View Related Profiles.

Upadhyay, Ashish
Verma, Ashish
Waikar, Sushrut

PMID: 32327275

Neves JS, Correa S, Baeta Baptista R, Bigotte Vieira M, Waikar SS, Mc Causland FR. Association of Prediabetes With CKD Progression and Adverse Cardiovascular Outcomes: An Analysis of the CRIC Study. J Clin Endocrinol Metab. 2020 04 01; 105(4). PMID: 31943096; PMCID: PMC7069215; DOI: 10.1210/clinem/dgaa017;

Greenberg JH, Abraham AG, Xu Y, Schelling JR, Feldman HI, Sabbisetti VS, Gonzalez MC, Coca S, Schrauben SJ, Waikar SS, Ramachandran VS, Shlipak MG, Warady B, Kimmel PL, Bonventre JV, Denburg M, Parikh CR, Furth S. Plasma Biomarkers of Tubular Injury and Inflammation Are Associated with CKD Progression in Children. J Am Soc Nephrol. 2020 05; 31(5):1067-1077.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 32234829; PMCID: PMC7217410; DOI: 10.1681/ASN.2019070723;

Chen Y, Zelnick LR, Wang K, Hoofnagle AN, Becker JO, Hsu CY, Feldman HI, Mehta RC, Lash JP, Waikar SS, Shafi T, Seliger SL, Shlipak MG, Rahman M, Kestenbaum BR. Kidney Clearance of Secretory Solutes Is Associated with Progression of CKD: The CRIC Study. J Am Soc Nephrol. 2020 04; 31(4):817-827. PMID: 32205410; PMCID: PMC7191931; DOI: 10.1681/ASN.2019080811;

Palsson R, Short SAP, Kibbelaar ZA, Amodu A, Stillman IE, Rennke HG, McMahon GM, Waikar SS. Bleeding Complications After Percutaneous Native Kidney Biopsy: Results From the Boston Kidney Biopsy Cohort. Kidney Int Rep. 2020 Apr; 5(4):511-518.View Related Profiles.

Amodu, Afolarin
Waikar, Sushrut

PMID: 32274455; PMCID: PMC7136322; DOI: 10.1016/j.ekir.2020.01.012;

Simic P, Kim W, Zhou W, Pierce KA, Chang W, Sykes DB, Aziz NB, Elmariah S, Ngo D, Pajevic PD, Govea N, Kestenbaum BR, de Boer IH, Cheng Z, Christov M, Chun J, Leaf DE, Waikar SS, Tager AM, Gerszten RE, Thadhani RI, Clish CB, Jüppner H, Wein MN, Rhee EP. Glycerol-3-phosphate is an FGF23 regulator derived from the injured kidney. J Clin Invest. 2020 03 02; 130(3):1513-1526.View Related Profiles.

Elmariah, Sammy
Waikar, Sushrut

PMID: 32065590; PMCID: PMC7269595; DOI: 10.1172/JCI131190;

Hayek SS, Leaf DE, Samman Tahhan A, Raad M, Sharma S, Waikar SS, Sever S, Camacho A, Wang X, Dande RR, Ibrahim NE, Baron RM, Altintas MM, Wei C, Sheikh-Hamad D, Pan JS, Holliday MW, Januzzi JL, Weisbord SD, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Acute Kidney Injury. N Engl J Med. 2020 01 30; 382(5):416-426. PMID: 31995687; PMCID: PMC7065830; DOI: 10.1056/NEJMoa1911481;

Gupta S, McMahon GM, Motwani SS, Mount DB, Waikar SS. "Pleurex Desalination" in Malignancy-related Ascites: A Novel Mechanism of Hyponatremia. Am J Clin Oncol. 2020 01; 43(1):14-19.View Related Profiles.

Mount, David Bruce
Waikar, Sushrut

PMID: 31592807; PMCID: PMC6917883; DOI: 10.1097/COC.0000000000000618;

Correa S, Pena-Esparragoza JK, Scovner KM, Waikar SS, Mc Causland FR. Myeloperoxidase and the Risk of CKD Progression, Cardiovascular Disease, and Death in the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 07; 76(1):32-41. PMID: 31864821

McMahon GM, Amodu A, Sise ME, Mothi SS, Palsson R, Waikar SS. Physician Attitudes on Kidney Biopsies for Research: A Survey Study. Kidney Med. 2020 Jan-Feb; 2(1):82-84.View Related Profiles.

Amodu, Afolarin
Waikar, Sushrut

PMID: 32734230; PMCID: PMC7380349; DOI: 10.1016/j.xkme.2019.10.009;

Ku E, Yang W, McCulloch CE, Feldman HI, Go AS, Lash J, Bansal N, He J, Horwitz E, Ricardo AC, Shafi T, Sondheimer J, Townsend RR, Waikar SS, Hsu CY. Race and Mortality in CKD and Dialysis: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2020 03; 75(3):394-403. PMID: 31732235; PMCID: PMC7042055; DOI: 10.1053/j.ajkd.2019.08.011;

Kefaloyianni E, Keerthi Raja MR, Schumacher J, Muthu ML, Krishnadoss V, Waikar SS, Herrlich A. Proximal Tubule-Derived Amphiregulin Amplifies and Integrates Profibrotic EGF Receptor Signals in Kidney Fibrosis. J Am Soc Nephrol. 2019 12; 30(12):2370-2383. PMID: 31676723; PMCID: PMC6900800; DOI: 10.1681/ASN.2019030321;

Wachterman MW, Leveille T, Keating NL, Simon SR, Waikar SS, Bokhour B. Nephrologists' emotional burden regarding decision-making about dialysis initiation in older adults: a qualitative study. BMC Nephrol. 2019 10 24; 20(1):385.View Related Profiles.

Bokhour, Barbara
Wachterman, Melissa
Simon, Steven R.
Waikar, Sushrut

PMID: 31651262; PMCID: PMC6814056; DOI: 10.1186/s12882-019-1565-x;

Wilson PC, Wu H, Kirita Y, Uchimura K, Ledru N, Rennke HG, Welling PA, Waikar SS, Humphreys BD. The single-cell transcriptomic landscape of early human diabetic nephropathy. Proc Natl Acad Sci U S A. 2019 09 24; 116(39):19619-19625. PMID: 31506348; PMCID: PMC6765272; DOI: 10.1073/pnas.1908706116;

Leaf DE, Waikar SS. IDEAL-ICU in Context. Clin J Am Soc Nephrol. 2019 08 07; 14(8):1264-1267. PMID: 31315886; PMCID: PMC6682815; DOI: 10.2215/CJN.01180119;

Efe O, Verma A, Waikar SS. Urinary oxalate as a potential mediator of kidney disease in diabetes mellitus and obesity. Curr Opin Nephrol Hypertens. 2019 07; 28(4):316-320.View Related Profiles.

Verma, Ashish
Waikar, Sushrut

PMID: 31045662; PMCID: PMC6687319; DOI: 10.1097/MNH.0000000000000515;

Leatherwood C, Speyer CB, Feldman CH, D'Silva K, Gómez-Puerta JA, Hoover PJ, Waikar SS, McMahon GM, Rennke HG, Costenbader KH. Clinical characteristics and renal prognosis associated with interstitial fibrosis and tubular atrophy (IFTA) and vascular injury in lupus nephritis biopsies. Semin Arthritis Rheum. 2019 12; 49(3):396-404. PMID: 31277928; PMCID: PMC6888990; DOI: 10.1016/j.semarthrit.2019.06.002;

Opotowsky AR, Carazo M, Singh MN, Dimopoulos K, Cardona-Estrada DA, Elantably A, Waikar SS, Mc Causland FR, Veldtman G, Grewal J, Gray C, Loukas BN, Rajpal S. Creatinine versus cystatin C to estimate glomerular filtration rate in adults with congenital heart disease: Results of the Boston Adult Congenital Heart Disease Biobank. Am Heart J. 2019 08; 214:142-155. PMID: 31203159

Sekulic M, Waikar S, Motwani SS, Weins A, Rennke HG. Chromogranin A Tubulopathy: Differing Histopathologic Patterns of Acute Tubular Injury in the Setting of Neuroendocrine Neoplasms. Kidney Int Rep. 2019 Aug; 4(8):1085-1093. PMID: 31440699; PMCID: PMC6698283; DOI: 10.1016/j.ekir.2019.04.025;

Sharma S, Christov M, Ix JH, Waikar SS. Clearance of FGF-23 during continuous renal replacement therapy. Hemodial Int. 2019 07; 23(3):366-368. PMID: 31037817

Mc Causland FR, Claggett B, Sabbisetti VS, Jarolim P, Waikar SS. Hypertonic Mannitol for the Prevention of Intradialytic Hypotension: A Randomized Controlled Trial. Am J Kidney Dis. 2019 10; 74(4):483-490. PMID: 31040088; PMCID: PMC6756938; DOI: 10.1053/j.ajkd.2019.03.415;

Waikar SS, Srivastava A, Palsson R, Shafi T, Hsu CY, Sharma K, Lash JP, Chen J, He J, Lieske J, Xie D, Zhang X, Feldman HI, Curhan GC. Association of Urinary Oxalate Excretion With the Risk of Chronic Kidney Disease Progression. JAMA Intern Med. 2019 04 01; 179(4):542-551. PMID: 30830167; PMCID: PMC6450310; DOI: 10.1001/jamainternmed.2018.7980;

Waikar SS. Precision nosology versus precision nephrology: defining acute kidney injury, again. Kidney Int. 2019 04; 95(4):741-743. PMID: 30904062

Naik GS, Waikar SS, Johnson AEW, Buchbinder EI, Haq R, Hodi FS, Schoenfeld JD, Ott PA. Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition. J Immunother Cancer. 2019 03 29; 7(1):89. PMID: 30922394; PMCID: PMC6440018; DOI: 10.1186/s40425-019-0512-5;

Mendu ML, Ahmed S, Maron JK, Rao SK, Chaguturu SK, May MF, Mutter WP, Burdge KA, Steele DJR, Mount DB, Waikar SS, Weilburg JB, Sequist TD. Development of an electronic health record-based chronic kidney disease registry to promote population health management. BMC Nephrol. 2019 03 01; 20(1):72.View Related Profiles.

Mount, David Bruce
Waikar, Sushrut

PMID: 30823871; PMCID: PMC6397481; DOI: 10.1186/s12882-019-1260-y;

Palsson R, Srivastava A, Waikar SS. Performance of the Automated Urinalysis in Diagnosis of Proliferative Glomerulonephritis. Kidney Int Rep. 2019 May; 4(5):723-727. PMID: 31080928; PMCID: PMC6506710; DOI: 10.1016/j.ekir.2019.02.001;

Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Boerger EAS, Mc Causland FR, Eisenga MF, Singh K, Babitt JL, Kellum JA, Palevsky PM, Christov M, Waikar SS. Iron, Hepcidin, and Death in Human AKI. J Am Soc Nephrol. 2019 03; 30(3):493-504. PMID: 30737269; PMCID: PMC6405140; DOI: 10.1681/ASN.2018100979;

Luo S, Coresh J, Tin A, Rebholz CM, Appel LJ, Chen J, Vasan RS, Anderson AH, Feldman HI, Kimmel PL, Waikar SS, Köttgen A, Evans AM, Levey AS, Inker LA, Sarnak MJ, Grams ME. Serum Metabolomic Alterations Associated with Proteinuria in CKD. Clin J Am Soc Nephrol. 2019 03 07; 14(3):342-353. PMID: 30733224; PMCID: PMC6419293; DOI: 10.2215/CJN.10010818;

Kelly YP, Waikar SS, Mendu ML. When to stop renal replacement therapy in anticipation of renal recovery in AKI: The need for consensus guidelines. Semin Dial. 2019 05; 32(3):205-209. PMID: 30690779

Srivastava A, Palsson R, Leaf DE, Higuera A, Chen ME, Palacios P, Baron RM, Sabbisetti V, Hoofnagle AN, Vaingankar SM, Palevsky PM, Waikar SS. Uric Acid and Acute Kidney Injury in the Critically Ill. Kidney Med. 2019 Jan-Feb; 1(1):21-30. PMID: 32734180; PMCID: PMC7380422; DOI: 10.1016/j.xkme.2019.01.003;

Coresh J, Heerspink HJL, Sang Y, Matsushita K, Arnlov J, Astor BC, Black C, Brunskill NJ, Carrero JJ, Feldman HI, Fox CS, Inker LA, Ishani A, Ito S, Jassal S, Konta T, Polkinghorne K, Romundstad S, Solbu MD, Stempniewicz N, Stengel B, Tonelli M, Umesawa M, Waikar SS, Wen CP, Wetzels JFM, Woodward M, Grams ME, Kovesdy CP, Levey AS, Gansevoort RT. Change in albuminuria and subsequent risk of end-stage kidney disease: an individual participant-level consortium meta-analysis of observational studies. Lancet Diabetes Endocrinol. 2019 02; 7(2):115-127. PMID: 30635225; PMCID: PMC6379893; DOI: 10.1016/S2213-8587(18)30313-9;

Palsson R, Chandraker AK, Curhan GC, Rennke HG, McMahon GM, Waikar SS. Erratum. Nephrol Dial Transplant. 2018 Dec 22; 36(4):747. PMID: 30590582; PMCID: PMC8008363; DOI: 10.1093/ndt/gfy364;

Rhee EP, Waikar SS, Rebholz CM, Zheng Z, Perichon R, Clish CB, Evans AM, Avila J, Denburg MR, Anderson AH, Vasan RS, Feldman HI, Kimmel PL, Coresh J. Variability of Two Metabolomic Platforms in CKD. Clin J Am Soc Nephrol. 2019 01 07; 14(1):40-48. PMID: 30573658; PMCID: PMC6364529; DOI: 10.2215/CJN.07070618;

Han Z, Xiao Z, Kalantar-Zadeh K, Moradi H, Shafi T, Waikar SS, Quarles LD, Yu Z, Tin A, Coresh J, Kovesdy CP. Validation of a Novel Modified Aptamer-Based Array Proteomic Platform in Patients with End-Stage Renal Disease. Diagnostics (Basel). 2018 Oct 08; 8(4). PMID: 30297602; PMCID: PMC6316431; DOI: 10.3390/diagnostics8040071;

Poyan Mehr A, Tran MT, Ralto KM, Leaf DE, Washco V, Messmer J, Lerner A, Kher A, Kim SH, Khoury CC, Herzig SJ, Trovato ME, Simon-Tillaux N, Lynch MR, Thadhani RI, Clish CB, Khabbaz KR, Rhee EP, Waikar SS, Berg AH, Parikh SM. De novo NAD+ biosynthetic impairment in acute kidney injury in humans. Nat Med. 2018 09; 24(9):1351-1359. PMID: 30127395; PMCID: PMC6129212; DOI: 10.1038/s41591-018-0138-z;

Waikar SS, Rebholz CM, Zheng Z, Hurwitz S, Hsu CY, Feldman HI, Xie D, Liu KD, Mifflin TE, Eckfeldt JH, Kimmel PL, Vasan RS, Bonventre JV, Inker LA, Coresh J. Biological Variability of Estimated GFR and Albuminuria in CKD. Am J Kidney Dis. 2018 10; 72(4):538-546. PMID: 30031564; PMCID: PMC6469385; DOI: 10.1053/j.ajkd.2018.04.023;

Srivastava A, Palsson R, Kaze AD, Chen ME, Palacios P, Sabbisetti V, Betensky RA, Steinman TI, Thadhani RI, McMahon GM, Stillman IE, Rennke HG, Waikar SS. The Prognostic Value of Histopathologic Lesions in Native Kidney Biopsy Specimens: Results from the Boston Kidney Biopsy Cohort Study. J Am Soc Nephrol. 2018 08; 29(8):2213-2224. PMID: 29866798; PMCID: PMC6065095; DOI: 10.1681/ASN.2017121260;

Palsson R, Waikar SS. Renal Functional Reserve Revisited. Adv Chronic Kidney Dis. 2018 05; 25(3):e1-e8. PMID: 29793670

Rajpal S, Alshawabkeh L, Almaddah N, Joyce CM, Shafer K, Gurvitz M, Waikar SS, Mc Causland FR, Landzberg MJ, Opotowsky AR. Association of Albuminuria With Major Adverse Outcomes in Adults With Congenital Heart Disease: Results From the Boston Adult Congenital Heart Biobank. JAMA Cardiol. 2018 04 01; 3(4):308-316. PMID: 29541749; PMCID: PMC5875351; DOI: 10.1001/jamacardio.2018.0125;

Leaf DE, Siew ED, Eisenga MF, Singh K, Mc Causland FR, Srivastava A, Ikizler TA, Ware LB, Ginde AA, Kellum JA, Palevsky PM, Wolf M, Waikar SS. Fibroblast Growth Factor 23 Associates with Death in Critically Ill Patients. Clin J Am Soc Nephrol. 2018 04 06; 13(4):531-541. PMID: 29519954; PMCID: PMC5969465; DOI: 10.2215/CJN.10810917;

Motwani SS, McMahon GM, Humphreys BD, Partridge AH, Waikar SS, Curhan GC. Development and Validation of a Risk Prediction Model for Acute Kidney Injury After the First Course of Cisplatin. J Clin Oncol. 2018 03 01; 36(7):682-688. PMID: 29320311; PMCID: PMC5946720; DOI: 10.1200/JCO.2017.75.7161;

Waikar SS, McMahon GM. Expanding the Role for Kidney Biopsies in Acute Kidney Injury. Semin Nephrol. 2018 01; 38(1):12-20. PMID: 29291757; PMCID: PMC5753426; DOI: 10.1016/j.semnephrol.2017.09.001;

Mendu ML, May MF, Kaze AD, Graham DA, Cui S, Chen ME, Shin N, Aizer AA, Waikar SS. Non-tunneled versus tunneled dialysis catheters for acute kidney injury requiring renal replacement therapy: a prospective cohort study. BMC Nephrol. 2017 Dec 04; 18(1):351. PMID: 29202728; PMCID: PMC5715550; DOI: 10.1186/s12882-017-0760-x;

Srivastava A, Kaze AD, McMullan CJ, Isakova T, Waikar SS. Uric Acid and the Risks of Kidney Failure and Death in Individuals With CKD. Am J Kidney Dis. 2018 03; 71(3):362-370. PMID: 29132945; PMCID: PMC5828916; DOI: 10.1053/j.ajkd.2017.08.017;

Rabadi S, Udo I, Leaf DE, Waikar SS, Christov M. Acute blood loss stimulates fibroblast growth factor 23 production. Am J Physiol Renal Physiol. 2018 01 01; 314(1):F132-F139. PMID: 28877877; PMCID: PMC5866351; DOI: 10.1152/ajprenal.00081.2017;

Kota SK, Pernicone E, Leaf DE, Stillman IE, Waikar SS, Kota SB. BPI Fold-Containing Family A Member 2/Parotid Secretory Protein Is an Early Biomarker of AKI. J Am Soc Nephrol. 2017 Dec; 28(12):3473-3478. PMID: 28775000; PMCID: PMC5698064; DOI: 10.1681/ASN.2016121265;

Singh K, Waikar SS, Samal L. Evaluating the feasibility of the KDIGO CKD referral recommendations. BMC Nephrol. 2017 Jul 07; 18(1):223. PMID: 28687072; PMCID: PMC5501411; DOI: 10.1186/s12882-017-0646-y;

Sharma S, Waikar SS. Intradialytic hypotension in acute kidney injury requiring renal replacement therapy. Semin Dial. 2017 11; 30(6):553-558. PMID: 28666082

Cardenas-Gonzalez M, Srivastava A, Pavkovic M, Bijol V, Rennke HG, Stillman IE, Zhang X, Parikh S, Rovin BH, Afkarian M, de Boer IH, Himmelfarb J, Waikar SS, Vaidya VS. Identification, Confirmation, and Replication of Novel Urinary MicroRNA Biomarkers in Lupus Nephritis and Diabetic Nephropathy. Clin Chem. 2017 Sep; 63(9):1515-1526. PMID: 28667184; PMCID: PMC5610914; DOI: 10.1373/clinchem.2017.274175;

Cui S, Vaingankar SM, Stenger A, Waikar SS, Leaf DE. Stability of Fibroblast Growth Factor 23 in Human Plasma. J Appl Lab Med. 2017 May 01; 1(6):729-734. PMID: 33379820

Gerarduzzi C, Kumar RK, Trivedi P, Ajay AK, Iyer A, Boswell S, Hutchinson JN, Waikar SS, Vaidya VS. Silencing SMOC2 ameliorates kidney fibrosis by inhibiting fibroblast to myofibroblast transformation. JCI Insight. 2017 Apr 20; 2(8). PMID: 28422762; PMCID: PMC5396522; DOI: 10.1172/jci.insight.90299;

Park M, Hsu CY, Go AS, Feldman HI, Xie D, Zhang X, Mifflin T, Waikar SS, Sabbisetti VS, Bonventre JV, Coresh J, Nelson RG, Kimmel PL, Kusek JW, Rahman M, Schelling JR, Vasan RS, Liu KD. Urine Kidney Injury Biomarkers and Risks of Cardiovascular Disease Events and All-Cause Death: The CRIC Study. Clin J Am Soc Nephrol. 2017 May 08; 12(5):761-771.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 28254771; PMCID: PMC5477212; DOI: 10.2215/CJN.08560816;

Zhao B, Lu Q, Cheng Y, Belcher JM, Siew ED, Leaf DE, Body SC, Fox AA, Waikar SS, Collard CD, Thiessen-Philbrook H, Ikizler TA, Ware LB, Edelstein CL, Garg AX, Choi M, Schaub JA, Zhao H, Lifton RP, Parikh CR. A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury. Am J Respir Crit Care Med. 2017 Feb 15; 195(4):482-490.View Related Profiles.

Body, Simon
Waikar, Sushrut

PMID: 27576016; PMCID: PMC5378420; DOI: 10.1164/rccm.201603-0518OC;

Emerson SC, Waikar SS, Fuentes C, Bonventre JV, Betensky RA. Biomarker validation with an imperfect reference: Issues and bounds. Stat Methods Med Res. 2018 10; 27(10):2933-2945. PMID: 28166709; PMCID: PMC5494007; DOI: 10.1177/0962280216689806;

Mendu ML, Waikar SS, Rao SK. Kidney Disease Population Health Management in the Era of Accountable Care: A Conceptual Framework for Optimizing Care Across the CKD Spectrum. Am J Kidney Dis. 2017 Jul; 70(1):122-131. PMID: 28132720

Mendu ML, Ciociolo GR, McLaughlin SR, Graham DA, Ghazinouri R, Parmar S, Grossier A, Rosen R, Laskowski KR, Riella LV, Robinson ES, Charytan DM, Bonventre JV, Greenberg JO, Waikar SS. A Decision-Making Algorithm for Initiation and Discontinuation of RRT in Severe AKI. Clin J Am Soc Nephrol. 2017 02 07; 12(2):228-236. PMID: 28119408; PMCID: PMC5293339; DOI: 10.2215/CJN.07170716;

Birmingham DJ, Merchant M, Waikar SS, Nagaraja H, Klein JB, Rovin BH. Biomarkers of lupus nephritis histology and flare: deciphering the relevant amidst the noise. Nephrol Dial Transplant. 2017 01 01; 32(suppl_1):i71-i79. PMID: 28391335; PMCID: PMC5837441; DOI: 10.1093/ndt/gfw300;

Leaf DE, Jacob KA, Srivastava A, Chen ME, Christov M, Jüppner H, Sabbisetti VS, Martin A, Wolf M, Waikar SS. Fibroblast Growth Factor 23 Levels Associate with AKI and Death in Critical Illness. J Am Soc Nephrol. 2017 Jun; 28(6):1877-1885. PMID: 28028134; PMCID: PMC5461795; DOI: 10.1681/ASN.2016080836;

Hsu CY, Xie D, Waikar SS, Bonventre JV, Zhang X, Sabbisetti V, Mifflin TE, Coresh J, Diamantidis CJ, He J, Lora CM, Miller ER, Nelson RG, Ojo AO, Rahman M, Schelling JR, Wilson FP, Kimmel PL, Feldman HI, Vasan RS, Liu KD. Urine biomarkers of tubular injury do not improve on the clinical model predicting chronic kidney disease progression. Kidney Int. 2017 Jan; 91(1):196-203.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 28029431; PMCID: PMC5362331; DOI: 10.1016/j.kint.2016.09.003;

Singh K, Betensky RA, Wright A, Curhan GC, Bates DW, Waikar SS. A Concept-Wide Association Study of Clinical Notes to Discover New Predictors of Kidney Failure. Clin J Am Soc Nephrol. 2016 12 07; 11(12):2150-2158. PMID: 27927892; PMCID: PMC5142057; DOI: 10.2215/CJN.02420316;

Mendu ML, Lundquist A, Aizer AA, Leaf DE, Robinson E, Steele DJ, Waikar SS. Clinical predictors of diagnostic testing utility in the initial evaluation of chronic kidney disease. Nephrology (Carlton). 2016 Oct; 21(10):851-9. PMID: 26610178; PMCID: PMC4969233; DOI: 10.1111/nep.12676;

Pang P, Abbott M, Chang SL, Abdi M, Chauhan N, Mistri M, Ghofrani J, Fucci QA, Walker C, Leonardi C, Grady S, Halim A, Hoffman R, Lu T, Cao H, Tullius SG, Malek S, Kumar S, Steele G, Kibel A, Freedman BS, Waikar SS, Siedlecki AM. Human vascular progenitor cells derived from renal arteries are endothelial-like and assist in the repair of injured renal capillary networks. Kidney Int. 2017 01; 91(1):129-143. PMID: 27692806; PMCID: PMC5179298; DOI: 10.1016/j.kint.2016.07.037;

Opotowsky AR, Baraona FR, Mc Causland FR, Loukas B, Landzberg E, Landzberg MJ, Sabbisetti V, Waikar SS. Estimated glomerular filtration rate and urine biomarkers in patients with single-ventricle Fontan circulation. Heart. 2017 03; 103(6):434-442. PMID: 27670967; PMCID: PMC5500305; DOI: 10.1136/heartjnl-2016-309729;

Leaf DE, Waikar SS. End Points for Clinical Trials in Acute Kidney Injury. Am J Kidney Dis. 2017 Jan; 69(1):108-116. PMID: 27599630; PMCID: PMC5182076; DOI: 10.1053/j.ajkd.2016.05.033;

Cui S, Heller HT, Waikar SS, McMahon GM. Needle Size and the Risk of Kidney Biopsy Bleeding Complications. Kidney Int Rep. 2016 Nov; 1(4):324-326. PMID: 29142935; PMCID: PMC5678857; DOI: 10.1016/j.ekir.2016.08.017;

Kefaloyianni E, Muthu ML, Kaeppler J, Sun X, Sabbisetti V, Chalaris A, Rose-John S, Wong E, Sagi I, Waikar SS, Rennke H, Humphreys BD, Bonventre JV, Herrlich A. ADAM17 substrate release in proximal tubule drives kidney fibrosis. JCI Insight. 2016 Aug 18; 1(13). PMID: 27642633; PMCID: PMC5026414; DOI: 10.1172/jci.insight.87023;

Mendu ML, McMahon GM, Licurse A, Solomon S, Greenberg J, Waikar SS. Electronic Consultations in Nephrology: Pilot Implementation and Evaluation. Am J Kidney Dis. 2016 Nov; 68(5):821-823. PMID: 27503182

Mc Causland FR, Asafu-Adjei J, Betensky RA, Palevsky PM, Waikar SS. Comparison of Urine Output among Patients Treated with More Intensive Versus Less Intensive RRT: Results from the Acute Renal Failure Trial Network Study. Clin J Am Soc Nephrol. 2016 08 08; 11(8):1335-42. PMID: 27449661; PMCID: PMC4974887; DOI: 10.2215/CJN.10991015;

Waikar SS, Sabbisetti V, Ärnlöv J, Carlsson AC, Coresh J, Feldman HI, Foster MC, Fufaa GD, Helmersson-Karlqvist J, Hsu CY, Kimmel PL, Larsson A, Liu Y, Lind L, Liu KD, Mifflin TE, Nelson RG, Risérus U, Vasan RS, Xie D, Zhang X, Bonventre JV. Relationship of proximal tubular injury to chronic kidney disease as assessed by urinary kidney injury molecule-1 in five cohort studies. Nephrol Dial Transplant. 2016 Sep; 31(9):1460-70.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 27270293; PMCID: PMC5009290; DOI: 10.1093/ndt/gfw203;

Leaf DE, Body SC, Muehlschlegel JD, McMahon GM, Lichtner P, Collard CD, Shernan SK, Fox AA, Waikar SS. Length Polymorphisms in Heme Oxygenase-1 and AKI after Cardiac Surgery. J Am Soc Nephrol. 2016 Nov; 27(11):3291-3297.View Related Profiles.

Body, Simon
Waikar, Sushrut

PMID: 27257045; PMCID: PMC5084897; DOI: 10.1681/ASN.2016010038;

Pavkovic M, Robinson-Cohen C, Chua AS, Nicoara O, Cárdenas-González M, Bijol V, Ramachandran K, Hampson L, Pirmohamed M, Antoine DJ, Frendl G, Himmelfarb J, Waikar SS, Vaidya VS. Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423. Toxicol Sci. 2016 07; 152(1):205-13. PMID: 27122240; PMCID: PMC5009468; DOI: 10.1093/toxsci/kfw077;

Leaf DE, Christov M, Jüppner H, Siew E, Ikizler TA, Bian A, Chen G, Sabbisetti VS, Bonventre JV, Cai X, Wolf M, Waikar SS. Fibroblast growth factor 23 levels are elevated and associated with severe acute kidney injury and death following cardiac surgery. Kidney Int. 2016 Apr; 89(4):939-48. PMID: 26924052; PMCID: PMC4801748; DOI: 10.1016/j.kint.2015.12.035;

Leaf DE, Srivastava A, Zeng X, McMahon GM, Croy HE, Mendu ML, Kachalia A, Waikar SS. Excessive diagnostic testing in acute kidney injury. BMC Nephrol. 2016 Jan 15; 17:9. PMID: 26772980; PMCID: PMC4714492; DOI: 10.1186/s12882-016-0224-8;

Waikar SS. Introduction: The Past, Present, and Future of AKI Therapeutics. Semin Nephrol. 2016 Jan; 36(1):7. PMID: 27085730

Mendu ML, Waikar SS. Electronic Health Record Patient Portals in CKD and Hypertension Management: Meaningfully Used? Clin J Am Soc Nephrol. 2015 Nov 06; 10(11):1897-9. PMID: 26493243; PMCID: PMC4633796; DOI: 10.2215/CJN.10070915;

Samal L, Wright A, Waikar SS, Linder JA. Nephrology co-management versus primary care solo management for early chronic kidney disease: a retrospective cross-sectional analysis. BMC Nephrol. 2015 Oct 12; 16:162. PMID: 26458541; PMCID: PMC4603818; DOI: 10.1186/s12882-015-0154-x;

Craciun FL, Bijol V, Ajay AK, Rao P, Kumar RK, Hutchinson J, Hofmann O, Joshi N, Luyendyk JP, Kusebauch U, Moss CL, Srivastava A, Himmelfarb J, Waikar SS, Moritz RL, Vaidya VS. RNA Sequencing Identifies Novel Translational Biomarkers of Kidney Fibrosis. J Am Soc Nephrol. 2016 06; 27(6):1702-13.View Related Profiles.

Craciun, Florin
Waikar, Sushrut

PMID: 26449608; PMCID: PMC4884105; DOI: 10.1681/ASN.2015020225;

Foster MC, Coresh J, Bonventre JV, Sabbisetti VS, Waikar SS, Mifflin TE, Nelson RG, Grams M, Feldman HI, Vasan RS, Kimmel PL, Hsu CY, Liu KD. Urinary Biomarkers and Risk of ESRD in the Atherosclerosis Risk in Communities Study. Clin J Am Soc Nephrol. 2015 Nov 6; 10(11):1956-63.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 26350438; PMCID: PMC4633784; DOI: 10.2215/CJN.02590315;

Kramann R, Fleig SV, Schneider RK, Fabian SL, DiRocco DP, Maarouf O, Wongboonsin J, Ikeda Y, Heckl D, Chang SL, Rennke HG, Waikar SS, Humphreys BD. Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis. J Clin Invest. 2015 Aug 03; 125(8):2935-51. PMID: 26193634; PMCID: PMC4563736; DOI: 10.1172/JCI74929;

Dasta J, Waikar SS, Xie L, Boklage S, Baser O, Chiodo J, Badawi O. Patterns of treatment and correction of hyponatremia in intensive care unit patients. J Crit Care. 2015 Oct; 30(5):1072-9. PMID: 26209428

Mc Causland FR, Waikar SS. Association of Predialysis Calculated Plasma Osmolarity With Intradialytic Blood Pressure Decline. Am J Kidney Dis. 2015 Sep; 66(3):499-506. PMID: 25975966; PMCID: PMC4782777; DOI: 10.1053/j.ajkd.2015.03.028;

Jacob KA, Leaf DE, Dieleman JM, van Dijk D, Nierich AP, Rosseel PM, van der Maaten JM, Hofland J, Diephuis JC, de Lange F, Boer C, Kluin J, Waikar SS. Intraoperative High-Dose Dexamethasone and Severe AKI after Cardiac Surgery. J Am Soc Nephrol. 2015 Dec; 26(12):2947-51. PMID: 25952257; PMCID: PMC4657835; DOI: 10.1681/ASN.2014080840;

Mendu ML, Lundquist A, Aizer AA, Leaf DE, Robinson E, Steele DJ, Waikar SS. The usefulness of diagnostic testing in the initial evaluation of chronic kidney disease. JAMA Intern Med. 2015 May; 175(5):853-6. PMID: 25730699; PMCID: PMC4420699; DOI: 10.1001/jamainternmed.2015.17;

Leaf DE, Croy HE, Abrahams SJ, Raed A, Waikar SS. Cathelicidin antimicrobial protein, vitamin D, and risk of death in critically ill patients. Crit Care. 2015 Mar 10; 19:80. PMID: 25887571; PMCID: PMC4357206; DOI: 10.1186/s13054-015-0812-1;

Hsu CY, Ballard S, Batlle D, Bonventre JV, Böttinger EP, Feldman HI, Klein JB, Coresh J, Eckfeldt JH, Inker LA, Kimmel PL, Kusek JW, Liu KD, Mauer M, Mifflin TE, Molitch ME, Nelsestuen GL, Rebholz CM, Rovin BH, Sabbisetti VS, Van Eyk JE, Vasan RS, Waikar SS, Whitehead KM, Nelson RG. Cross-Disciplinary Biomarkers Research: Lessons Learned by the CKD Biomarkers Consortium. Clin J Am Soc Nephrol. 2015 May 7; 10(5):894-902.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 25739849; PMCID: PMC4422251; DOI: 10.2215/CJN.11541114;

Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Rawn JD, Frendl G, Waikar SS. Increased plasma catalytic iron in patients may mediate acute kidney injury and death following cardiac surgery. Kidney Int. 2015 May; 87(5):1046-54. PMID: 25565307; PMCID: PMC5137505; DOI: 10.1038/ki.2014.374;

Sharma S, Brugnara C, Betensky RA, Waikar SS. Reductions in red blood cell 2,3-diphosphoglycerate concentration during continuous renal replacment therapy. Clin J Am Soc Nephrol. 2015 Jan 07; 10(1):74-9. PMID: 25538269; PMCID: PMC4284404; DOI: 10.2215/CJN.02160214;

Leaf DE, Raed A, Donnino MW, Ginde AA, Waikar SS. Reply: active and native vitamin D in critical illness. Am J Respir Crit Care Med. 2014 Nov 15; 190(10):1194-6. PMID: 25398113; PMCID: PMC7710327; DOI: 10.1164/rccm.201408-1454LE;

Fufaa GD, Weil EJ, Nelson RG, Hanson RL, Bonventre JV, Sabbisetti V, Waikar SS, Mifflin TE, Zhang X, Xie D, Hsu CY, Feldman HI, Coresh J, Vasan RS, Kimmel PL, Liu KD. Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus. Diabetologia. 2015 Jan; 58(1):188-98.View Related Profiles.

Waikar, Sushrut
Ramachandran, Vasan

PMID: 25316431; PMCID: PMC4258130; DOI: 10.1007/s00125-014-3389-3;

Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Waikar SS. Plasma catalytic iron, AKI, and death among critically ill patients. Clin J Am Soc Nephrol. 2014 Nov 07; 9(11):1849-56. PMID: 25189925; PMCID: PMC4220757; DOI: 10.2215/CJN.02840314;

Leaf DE, Waikar SS. Rosuvastatin for sepsis-associated ARDS. N Engl J Med. 2014 09 04; 371(10):968. PMID: 25184877

Leaf DE, Raed A, Donnino MW, Ginde AA, Waikar SS. Randomized controlled trial of calcitriol in severe sepsis. Am J Respir Crit Care Med. 2014 Sep 01; 190(5):533-41. PMID: 25029202; PMCID: PMC4214090; DOI: 10.1164/rccm.201405-0988OC;

Mendu ML, Schneider LI, Aizer AA, Singh K, Leaf DE, Lee TH, Waikar SS. Implementation of a CKD checklist for primary care providers. Clin J Am Soc Nephrol. 2014 Sep 05; 9(9):1526-35. PMID: 25135764; PMCID: PMC4152808; DOI: 10.2215/CJN.01660214;

Mc Causland F, Wright J, Waikar S. In response to "Association of serum sodium with morbidity and mortality in hospitalized patients undergoing major orthopedic surgery". J Hosp Med. 2014 Sep; 9(9):613. PMID: 24965087

Sabbisetti VS, Waikar SS, Antoine DJ, Smiles A, Wang C, Ravisankar A, Ito K, Sharma S, Ramadesikan S, Lee M, Briskin R, De Jager PL, Ngo TT, Radlinski M, Dear JW, Park KB, Betensky R, Krolewski AS, Bonventre JV. Blood kidney injury molecule-1 is a biomarker of acute and chronic kidney injury and predicts progression to ESRD in type I diabetes. J Am Soc Nephrol. 2014 Oct; 25(10):2177-86. PMID: 24904085; PMCID: PMC4178434; DOI: 10.1681/ASN.2013070758;

Mendu ML, Waikar SS. Drug-drug interactions and acute kidney injury: caveat prescriptor. Am J Kidney Dis. 2014 Oct; 64(4):492-4. PMID: 24820318; PMCID: PMC4391370; DOI: 10.1053/j.ajkd.2014.04.015;

Mc Causland FR, Wright J, Waikar SS. Association of serum sodium with morbidity and mortality in hospitalized patients undergoing major orthopedic surgery. J Hosp Med. 2014 May; 9(5):297-302. PMID: 24523043; PMCID: PMC4815900; DOI: 10.1002/jhm.2168;

Grams ME, Waikar SS, MacMahon B, Whelton S, Ballew SH, Coresh J. Performance and limitations of administrative data in the identification of AKI. Clin J Am Soc Nephrol. 2014 Apr; 9(4):682-9. PMID: 24458075; PMCID: PMC3974361; DOI: 10.2215/CJN.07650713;

Mc Causland FR, Waikar SS. Optimal dialysate sodium-what is the evidence? Semin Dial. 2014 Mar; 27(2):128-34. PMID: 24450281; PMCID: PMC5500308; DOI: 10.1111/sdi.12182;

Nakahira K, Kyung SY, Rogers AJ, Gazourian L, Youn S, Massaro AF, Quintana C, Osorio JC, Wang Z, Zhao Y, Lawler LA, Christie JD, Meyer NJ, Mc Causland FR, Waikar SS, Waxman AB, Chung RT, Bueno R, Rosas IO, Fredenburgh LE, Baron RM, Christiani DC, Hunninghake GM, Choi AM. Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation. PLoS Med. 2013 Dec; 10(12):e1001577; discussion e1001577. PMID: 24391478; PMCID: PMC3876981; DOI: 10.1371/journal.pmed.1001577;

Gómez-Puerta JA, Waikar SS, Solomon DH, Liu J, Alarcón GS, Winkelmayer WC, Costenbader KH. Erythropoiesis-stimulating Agent Use among Patients with Lupus Nephritis Approaching End-stage Renal Disease. J Clin Cell Immunol. 2013 Dec 01; 4(6):179. PMID: 24672742; PMCID: PMC3963515; DOI: 10.4172/2155-9899.1000179;

Zeng X, McMahon GM, Brunelli SM, Bates DW, Waikar SS. Incidence, outcomes, and comparisons across definitions of AKI in hospitalized individuals. Clin J Am Soc Nephrol. 2014 Jan; 9(1):12-20. PMID: 24178971; PMCID: PMC3878695; DOI: 10.2215/CJN.02730313;

McMahon GM, Zeng X, Waikar SS. A risk prediction score for kidney failure or mortality in rhabdomyolysis. JAMA Intern Med. 2013 Oct 28; 173(19):1821-8. PMID: 24000014; PMCID: PMC5152583; DOI: 10.1001/jamainternmed.2013.9774;

Mc Causland FR, Brunelli SM, Waikar SS. Dialysis dose and intradialytic hypotension: results from the HEMO study. Am J Nephrol. 2013; 38(5):388-96. PMID: 24192428; PMCID: PMC3904183; DOI: 10.1159/000355958;

Ramachandran K, Saikumar J, Bijol V, Koyner JL, Qian J, Betensky RA, Waikar SS, Vaidya VS. Human miRNome profiling identifies microRNAs differentially present in the urine after kidney injury. Clin Chem. 2013 Dec; 59(12):1742-52. PMID: 24153252; PMCID: PMC3870155; DOI: 10.1373/clinchem.2013.210245;

Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Imperfect gold standards for biomarker evaluation. Clin Trials. 2013 Oct; 10(5):696-700. PMID: 24006246; PMCID: PMC3800226; DOI: 10.1177/1740774513497540;

Wachterman MW, Marcantonio ER, Davis RB, Cohen RA, Waikar SS, Phillips RS, McCarthy EP. Relationship between the prognostic expectations of seriously ill patients undergoing hemodialysis and their nephrologists. JAMA Intern Med. 2013 Jul 8; 173(13):1206-14.View Related Profiles.

Wachterman, Melissa
Waikar, Sushrut

PMID: 23712681; PMCID: PMC3982381; DOI: 10.1001/jamainternmed.2013.6036;

McCullough PA, Shaw AD, Haase M, Bouchard J, Waikar SS, Siew ED, Murray PT, Mehta RL, Ronco C. Diagnosis of acute kidney injury using functional and injury biomarkers: workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference. Contrib Nephrol. 2013; 182:13-29. PMID: 23689653

McCullough PA, Bouchard J, Waikar SS, Siew ED, Endre ZH, Goldstein SL, Koyner JL, Macedo E, Doi K, Di Somma S, Lewington A, Thadhani R, Chakravarthi R, Ice C, Okusa MD, Duranteau J, Doran P, Yang L, Jaber BL, Meehan S, Kellum JA, Haase M, Murray PT, Cruz D, Maisel A, Bagshaw SM, Chawla LS, Mehta RL, Shaw AD, Ronco C. Implementation of novel biomarkers in the diagnosis, prognosis, and management of acute kidney injury: executive summary from the tenth consensus conference of the Acute Dialysis Quality Initiative (ADQI). Contrib Nephrol. 2013; 182:5-12. PMID: 23689652; PMCID: PMC3856225; DOI: 10.1159/000349962;

Christov M, Waikar SS, Pereira RC, Havasi A, Leaf DE, Goltzman D, Pajevic PD, Wolf M, Jüppner H. Plasma FGF23 levels increase rapidly after acute kidney injury. Kidney Int. 2013 Oct; 84(4):776-85.View Related Profiles.

Havasi, Andrea
Divieti Pajevic, Paola
Waikar, Sushrut

PMID: 23657144; PMCID: PMC3766419; DOI: 10.1038/ki.2013.150;

Leaf DE, Waikar SS, Wolf M, Cremers S, Bhan I, Stern L. Dysregulated mineral metabolism in patients with acute kidney injury and risk of adverse outcomes. Clin Endocrinol (Oxf). 2013 Oct; 79(4):491-8. PMID: 23414198; PMCID: PMC3686895; DOI: 10.1111/cen.12172;

Palevsky PM, Liu KD, Brophy PD, Chawla LS, Parikh CR, Thakar CV, Tolwani AJ, Waikar SS, Weisbord SD. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury. Am J Kidney Dis. 2013 May; 61(5):649-72. PMID: 23499048

McMahon GM, Waikar SS. Biomarkers in nephrology: Core Curriculum 2013. Am J Kidney Dis. 2013 Jul; 62(1):165-78. PMID: 23455173; PMCID: PMC3686906; DOI: 10.1053/j.ajkd.2012.12.022;

Sharma S, Waikar SS. Phosphate balance in continuous venovenous hemofiltration. Am J Kidney Dis. 2013 Jun; 61(6):1043-5. PMID: 23434061; PMCID: PMC5152589; DOI: 10.1053/j.ajkd.2012.12.026;

Mc Causland FR, Waikar SS, Brunelli SM. The relevance of dietary sodium in hemodialysis. Nephrol Dial Transplant. 2013 Apr; 28(4):797-802. PMID: 23129821; PMCID: PMC3716331; DOI: 10.1093/ndt/gfs452;

Waikar SS, Winkelmayer WC. Saving the kidneys by sparing intravenous chloride? JAMA. 2012 Oct 17; 308(15):1583-5. PMID: 23073956

Brunelli SM, Waikar SS, Bateman BT, Chang TI, Lii J, Garg AX, Winkelmayer WC, Choudhry NK. Preoperative statin use and postoperative acute kidney injury. Am J Med. 2012 Dec; 125(12):1195-1204.e3. PMID: 23062398; PMCID: PMC3597342; DOI: 10.1016/j.amjmed.2012.06.021;

Zhou S, Leboff MS, Waikar SS, Glowacki J. Vitamin D metabolism and action in human marrow stromal cells: effects of chronic kidney disease. J Steroid Biochem Mol Biol. 2013 Jul; 136:342-4. PMID: 22989482; PMCID: PMC3535685; DOI: 10.1016/j.jsbmb.2012.09.009;

Mc Causland FR, Brunelli SM, Waikar SS. Association of smoking with cardiovascular and infection-related morbidity and mortality in chronic hemodialysis. Clin J Am Soc Nephrol. 2012 Nov; 7(11):1827-35. PMID: 22917700; PMCID: PMC3488948; DOI: 10.2215/CJN.03880412;

Mc Causland FR, Prior LM, Heher E, Waikar SS. Preservation of blood pressure stability with hypertonic mannitol during hemodialysis initiation. Am J Nephrol. 2012; 36(2):168-74. PMID: 22846598; PMCID: PMC3779621; DOI: 10.1159/000341273;

Hoffmann D, Bijol V, Krishnamoorthy A, Gonzalez VR, Frendl G, Zhang Q, Goering PL, Brown RP, Waikar SS, Vaidya VS. Fibrinogen excretion in the urine and immunoreactivity in the kidney serves as a translational biomarker for acute kidney injury. Am J Pathol. 2012 Sep; 181(3):818-28. PMID: 22819533; PMCID: PMC3432430; DOI: 10.1016/j.ajpath.2012.06.004;

Saikumar J, Hoffmann D, Kim TM, Gonzalez VR, Zhang Q, Goering PL, Brown RP, Bijol V, Park PJ, Waikar SS, Vaidya VS. Expression, circulation, and excretion profile of microRNA-21, -155, and -18a following acute kidney injury. Toxicol Sci. 2012 Oct; 129(2):256-67. PMID: 22705808; PMCID: PMC3499041; DOI: 10.1093/toxsci/kfs210;

Leaf DE, Wolf M, Waikar SS, Chase H, Christov M, Cremers S, Stern L. FGF-23 levels in patients with AKI and risk of adverse outcomes. Clin J Am Soc Nephrol. 2012 Aug; 7(8):1217-23. PMID: 22700885; PMCID: PMC3408118; DOI: 10.2215/CJN.00550112;

Mizuguchi KA, Mitani A, Waikar SS, Ireland P, Panizales C, Deluke G, Sugarbaker DJ, Bonventre JV, Frendl G. Use of postoperative creatinine to predict sustained kidney injury in patients undergoing mesothelioma surgery. Clin J Am Soc Nephrol. 2012 Jul; 7(7):1071-8. PMID: 22537654; PMCID: PMC3386676; DOI: 10.2215/CJN.12401211;

Okusa MD, Molitoris BA, Palevsky PM, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Faubel S, Kellum JA, Wald R, Chertow GM, Levin A, Waikar SS, Murray PT, Parikh CR, Shaw AD, Go AS, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene TH, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in acute kidney injury: a report from an NIDDK workshop--prevention trials. Clin J Am Soc Nephrol. 2012 May; 7(5):851-5.View Related Profiles.

Kaufman, James
Waikar, Sushrut

PMID: 22442188; DOI: 10.2215/CJN.12811211;

Molitoris BA, Okusa MD, Palevsky PM, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene TH, Faubel SG, Kellum JA, Wald R, Chertow GM, Levin A, Waikar SS, Murray PT, Parikh CR, Shaw AD, Go AS, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings. Clin J Am Soc Nephrol. 2012 May; 7(5):856-60.View Related Profiles.

Kaufman, James
Waikar, Sushrut

PMID: 22442184; DOI: 10.2215/CJN.12821211;

Palevsky PM, Molitoris BA, Okusa MD, Levin A, Waikar SS, Wald R, Chertow GM, Murray PT, Parikh CR, Shaw AD, Go AS, Faubel SG, Kellum JA, Chinchilli VM, Liu KD, Cheung AK, Weisbord SD, Chawla LS, Kaufman JS, Devarajan P, Toto RM, Hsu CY, Greene T, Mehta RL, Stokes JB, Thompson AM, Thompson BT, Westenfelder CS, Tumlin JA, Warnock DG, Shah SV, Xie Y, Duggan EG, Kimmel PL, Star RA. Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology. Clin J Am Soc Nephrol. 2012 May; 7(5):844-50.View Related Profiles.

Kaufman, James
Waikar, Sushrut

PMID: 22442182; DOI: 10.2215/CJN.12791211;

Mc Causland FR, Waikar SS, Brunelli SM. Increased dietary sodium is independently associated with greater mortality among prevalent hemodialysis patients. Kidney Int. 2012 Jul; 82(2):204-11. PMID: 22418981; PMCID: PMC3779624; DOI: 10.1038/ki.2012.42;

Ferguson MA, Waikar SS. Established and emerging markers of kidney function. Clin Chem. 2012 Apr; 58(4):680-9. PMID: 22311920; PMCID: PMC5136473; DOI: 10.1373/clinchem.2011.167494;

Mc Causland FR, Tilley BS, Waikar SS. Dialysate sodium and the milieu intérieur. Clin J Am Soc Nephrol. 2012 Jan; 7(1):5-7. PMID: 22173861

Devlin A, Waikar SS, Solomon DH, Lu B, Shaykevich T, Alarcón GS, Winkelmayer WC, Costenbader KH. Variation in initial kidney replacement therapy for end-stage renal disease due to lupus nephritis in the United States. Arthritis Care Res (Hoboken). 2011 Dec; 63(12):1642-53. PMID: 22058067; PMCID: PMC3227771; DOI: 10.1002/acr.20607;

Mandelbaum T, Scott DJ, Lee J, Mark RG, Malhotra A, Waikar SS, Howell MD, Talmor D. Outcome of critically ill patients with acute kidney injury using the Acute Kidney Injury Network criteria. Crit Care Med. 2011 Dec; 39(12):2659-64. PMID: 21765352; PMCID: PMC3213281; DOI: 10.1097/CCM.0b013e3182281f1b;

Nigwekar SU, Waikar SS. Diuretics in acute kidney injury. Semin Nephrol. 2011 Nov; 31(6):523-34. PMID: 22099509

Waikar SS, Betensky RA, Emerson SC, Bonventre JV. Imperfect gold standards for kidney injury biomarker evaluation. J Am Soc Nephrol. 2012 Jan; 23(1):13-21. PMID: 22021710; PMCID: PMC3695762; DOI: 10.1681/ASN.2010111124;

Mc Causland FR, Brunelli SM, Waikar SS. Dialysate sodium, serum sodium and mortality in maintenance hemodialysis. Nephrol Dial Transplant. 2012 Apr; 27(4):1613-8. PMID: 21891777; PMCID: PMC3471551; DOI: 10.1093/ndt/gfr497;

Krishnamoorthy A, Ajay AK, Hoffmann D, Kim TM, Ramirez V, Campanholle G, Bobadilla NA, Waikar SS, Vaidya VS. Fibrinogen ß-derived Bß(15-42) peptide protects against kidney ischemia/reperfusion injury. Blood. 2011 Aug 18; 118(7):1934-42. PMID: 21685370; PMCID: PMC3158721; DOI: 10.1182/blood-2011-02-338061;

Waikar SS, Brunelli SM. Peri-surgical statins lessen acute kidney injury. J Am Soc Nephrol. 2011 May; 22(5):797-9. PMID: 21493777

Waikar SS, Curhan GC, Brunelli SM. Mortality associated with low serum sodium concentration in maintenance hemodialysis. Am J Med. 2011 Jan; 124(1):77-84. PMID: 21187188; PMCID: PMC3040578; DOI: 10.1016/j.amjmed.2010.07.029;

Waikar SS, Sabbisetti VS, Bonventre JV. Normalization of urinary biomarkers to creatinine during changes in glomerular filtration rate. Kidney Int. 2010 Sep; 78(5):486-94. PMID: 20555318; PMCID: PMC3025699; DOI: 10.1038/ki.2010.165;

Gabardi S, Waikar SS, Martin S, Roberts K, Chen J, Borgi L, Sheashaa H, Dyer C, Malek SK, Tullius SG, Vadivel N, Grafals M, Abdi R, Najafian N, Milford E, Chandraker A. Evaluation of fluoroquinolones for the prevention of BK viremia after renal transplantation. Clin J Am Soc Nephrol. 2010 Jul; 5(7):1298-304. PMID: 20507960; PMCID: PMC2893065; DOI: 10.2215/CJN.08261109;

James MT, Wald R, Bell CM, Tonelli M, Hemmelgarn BR, Waikar SS, Chertow GM. Weekend hospital admission, acute kidney injury, and mortality. J Am Soc Nephrol. 2010 May; 21(5):845-51. PMID: 20395373; PMCID: PMC2865737; DOI: 10.1681/ASN.2009070682;

Ferguson MA, Vaidya VS, Waikar SS, Collings FB, Sunderland KE, Gioules CJ, Bonventre JV. Urinary liver-type fatty acid-binding protein predicts adverse outcomes in acute kidney injury. Kidney Int. 2010 Apr; 77(8):708-14. PMID: 19940842; PMCID: PMC2880954; DOI: 10.1038/ki.2009.422;

Waikar SS, Winkelmayer WC. Chronic on acute renal failure: long-term implications of severe acute kidney injury. JAMA. 2009 Sep 16; 302(11):1227-9. PMID: 19755705

Waikar SS, Betensky RA, Bonventre JV. Creatinine as the gold standard for kidney injury biomarker studies? Nephrol Dial Transplant. 2009 Nov; 24(11):3263-5. PMID: 19736243

Waikar SS, Mount DB, Curhan GC. Mortality after hospitalization with mild, moderate, and severe hyponatremia. Am J Med. 2009 Sep; 122(9):857-65.View Related Profiles.

Mount, David Bruce
Waikar, Sushrut

PMID: 19699382; PMCID: PMC3033702; DOI: 10.1016/j.amjmed.2009.01.027;

Vaidya VS, Ford GM, Waikar SS, Wang Y, Clement MB, Ramirez V, Glaab WE, Troth SP, Sistare FD, Prozialeck WC, Edwards JR, Bobadilla NA, Mefferd SC, Bonventre JV. A rapid urine test for early detection of kidney injury. Kidney Int. 2009 Jul; 76(1):108-14. PMID: 19387469; PMCID: PMC2737345; DOI: 10.1038/ki.2009.96;

Waikar SS, Bonventre JV. Creatinine kinetics and the definition of acute kidney injury. J Am Soc Nephrol. 2009 Mar; 20(3):672-9. PMID: 19244578; PMCID: PMC2653692; DOI: 10.1681/ASN.2008070669;

Winkelmayer WC, Waikar SS, Mogun H, Solomon DH. Nonselective and cyclooxygenase-2-selective NSAIDs and acute kidney injury. Am J Med. 2008 Dec; 121(12):1092-8. PMID: 19028206

Vaidya VS, Waikar SS, Ferguson MA, Collings FB, Sunderland K, Gioules C, Bradwin G, Matsouaka R, Betensky RA, Curhan GC, Bonventre JV. Urinary biomarkers for sensitive and specific detection of acute kidney injury in humans. Clin Transl Sci. 2008 Dec; 1(3):200-8. PMID: 19212447; PMCID: PMC2638059; DOI: 10.1111/j.1752-8062.2008.00053.x;

Waikar SS, Bonventre JV. Biomarkers for the diagnosis of acute kidney injury. Nephron Clin Pract. 2008; 109(4):c192-7. PMID: 18802367; PMCID: PMC2713682; DOI: 10.1159/000142928;

Rocuts AK, Waikar SS, Alexander MP, Rennke HG, Singh AK. Acute phosphate nephropathy. Kidney Int. 2009 May; 75(9):987-91. PMID: 18580858

Chertow GM, Waikar SS. Toward the promise of renal replacement therapy. J Am Soc Nephrol. 2008 May; 19(5):839-40. PMID: 18385414

Waikar SS, Liu KD, Chertow GM. Diagnosis, epidemiology and outcomes of acute kidney injury. Clin J Am Soc Nephrol. 2008 May; 3(3):844-61. PMID: 18337550

Waikar SS, Bonventre JV. Biomarkers for the diagnosis of acute kidney injury. Curr Opin Nephrol Hypertens. 2007 Nov; 16(6):557-64. PMID: 18089971

Waikar SS, Curhan GC, Ayanian JZ, Chertow GM. Race and mortality after acute renal failure. J Am Soc Nephrol. 2007 Oct; 18(10):2740-8. PMID: 17855647; PMCID: PMC3023164; DOI: 10.1681/ASN.2006091060;

Waikar SS, Liu KD, Chertow GM. The incidence and prognostic significance of acute kidney injury. Curr Opin Nephrol Hypertens. 2007 May; 16(3):227-36. PMID: 17420666; PMCID: PMC3027554; DOI: 10.1097/MNH.0b013e3280dd8c35;

Waikar SS, Bonventre JV. Can we rely on blood urea nitrogen as a biomarker to determine when to initiate dialysis? Clin J Am Soc Nephrol. 2006 Sep; 1(5):903-4. PMID: 17699303

Waikar SS, Wald R, Chertow GM, Curhan GC, Winkelmayer WC, Liangos O, Sosa MA, Jaber BL. Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Acute Renal Failure. J Am Soc Nephrol. 2006 Jun; 17(6):1688-94. PMID: 16641149

Wald R, Waikar SS, Liangos O, Pereira BJ, Chertow GM, Jaber BL. Acute renal failure after endovascular vs open repair of abdominal aortic aneurysm. J Vasc Surg. 2006 Mar; 43(3):460-466; discussion 466. PMID: 16520155

Waikar SS, Curhan GC, Wald R, McCarthy EP, Chertow GM. Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol. 2006 Apr; 17(4):1143-50. PMID: 16495376

Kirtane AJ, Leder DM, Waikar SS, Chertow GM, Ray KK, Pinto DS, Karmpaliotis D, Burger AJ, Murphy SA, Cannon CP, Braunwald E, Gibson CM. Serum blood urea nitrogen as an independent marker of subsequent mortality among patients with acute coronary syndromes and normal to mildly reduced glomerular filtration rates. J Am Coll Cardiol. 2005 Jun 07; 45(11):1781-6. PMID: 15936606

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 279 publications over 19 distinct years, with a maximum of 41 publications in 2021

Bar chart showing 279 publications over 19 distinct years, with a maximum of 41 publications in 2021

Year	Publications
2005	1
2006	4
2007	3
2008	6
2009	6
2010	3
2011	9
2012	15
2013	15
2014	13
2015	12
2016	17
2017	15
2018	11
2019	23
2020	36
2021	41
2022	28
2023	21

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