David Bruce Mount | Profiles RNS

David Bruce Mount, MD

Adjunct Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Nephrology

MD, University of Toronto
BSc, University of Ottawa

Websites

	Brigham and Women's Hospital
	Harvard Catalyst
	LinkedIn
	Mass General Brigham Profile

Other Positions
Publications

VA Boston Healthcare System

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Mandal AK, Merriman TR, Choi HK, Mount DB. Caffeine Inhibits Both Basal and Insulin-Activated Urate Transport. Arthritis Rheumatol. 2024 Jun 26. PMID: 38932509

Mount DB. Requiem for Urate Lowering in CKD? J Am Soc Nephrol. 2024 May 01; 35(5):525-527. PMID: 38598292; PMCID: PMC11149040; DOI: 10.1681/ASN.0000000000000352;

Estiverne C, McMahon GM, Mount DB, Bianchi G, Pierce CD, Hakim H, Rennke HG, Czarnecki PG. Safety and Diagnostic Yield of Protocolized Percutaneous Kidney Biopsies in Mechanically Ventilated Patients With Acute Kidney Injury. Kidney Int Rep. 2023 Jun; 8(6):1255-1259. PMID: 37284670; PMCID: PMC10239768; DOI: 10.1016/j.ekir.2023.03.007;

Mandal AK, Leask MP, Sumpter NA, Choi HK, Merriman TR, Mount DB. Genetic and Physiological Effects of Insulin-Like Growth Factor-1 (IGF-1) on Human Urate Homeostasis. J Am Soc Nephrol. 2023 Mar 01; 34(3):451-466. PMID: 36735516; PMCID: PMC10103387; DOI: 10.1681/ASN.0000000000000054;

He Y, Xue X, Terkeltaub R, Dalbeth N, Merriman TR, Mount DB, Feng Z, Li X, Cui L, Liu Z, Xu Y, Chen Y, Li H, Ji A, Ji X, Wang X, Lu J, Li C. Association of acidic urine pH with impaired renal function in primary gout patients: a Chinese population-based cross-sectional study. Arthritis Res Ther. 2022 01 25; 24(1):32. PMID: 35078513; PMCID: PMC8787907; DOI: 10.1186/s13075-022-02725-w;

Zhuo M, Li J, Buckley LF, Tummalapalli SL, Mount DB, Steele DJR, Lucier DJ, Mendu ML. Prescribing Patterns of Sodium-Glucose Cotransporter-2 Inhibitors in Patients with CKD: A Cross-Sectional Registry Analysis. Kidney360. 2022 Mar 31; 3(3):455-464. PMID: 35582176; PMCID: PMC9034822; DOI: 10.34067/KID.0007862021;

McCormick N, O'Connor MJ, Yokose C, Merriman TR, Mount DB, Leong A, Choi HK. Assessing the Causal Relationships Between Insulin Resistance and Hyperuricemia and Gout Using Bidirectional Mendelian Randomization. Arthritis Rheumatol. 2021 11; 73(11):2096-2104. PMID: 33982892; PMCID: PMC8568618; DOI: 10.1002/art.41779;

Mandal AK, Leask MP, Estiverne C, Choi HK, Merriman TR, Mount DB. Genetic and Physiological Effects of Insulin on Human Urate Homeostasis. Front Physiol. 2021; 12:713710. PMID: 34408667; PMCID: PMC8366499; DOI: 10.3389/fphys.2021.713710;

Stamp LK, Farquhar H, Pisaniello HL, Vargas-Santos AB, Fisher M, Mount DB, Choi HK, Terkeltaub R, Hill CL, Gaffo AL. Management of gout in chronic kidney disease: a G-CAN Consensus Statement on the research priorities. Nat Rev Rheumatol. 2021 10; 17(10):633-641. PMID: 34331037; PMCID: PMC8458096; DOI: 10.1038/s41584-021-00657-4;

Wongboonsin J, Shah SI, Marty FM, Mount DB, Rennke HG, Murakami N. Osmotic Tubulopathy in a Patient With COVID-19 Treated With Remdesivir. Kidney Int Rep. 2021 Jul; 6(7):1987-1991. PMID: 33997535; PMCID: PMC8112887; DOI: 10.1016/j.ekir.2021.04.032;

Showing 10 of 61 results. Show More

Efe O, García JDC, Mount DB, Sheridan AM. Refractory hypophosphatemia following ferric carboxymaltose administration. CEN Case Rep. 2021 11; 10(4):473-475. PMID: 33715107; PMCID: PMC8494864; DOI: 10.1007/s13730-021-00590-1;

Estiverne C, Mount DB. The Management of Gout in Renal Disease. Semin Nephrol. 2020 11; 40(6):600-613. PMID: 33678314

Leask MP, Sumpter NA, Lupi AS, Vazquez AI, Reynolds RJ, Mount DB, Merriman TR. The Shared Genetic Basis of Hyperuricemia, Gout, and Kidney Function. Semin Nephrol. 2020 11; 40(6):586-599. PMID: 33678313

Estiverne C, Mandal AK, Mount DB. Molecular Pathophysiology of Uric Acid Homeostasis. Semin Nephrol. 2020 11; 40(6):535-549. PMID: 33678309

Mount DB. Introduction: Gout and the Kidney. Semin Nephrol. 2020 11; 40(6):533-534. PMID: 33678308

Gupta S, Tio MC, Gutowski ED, Stecker MS, Verma A, Motwani SS, Mount DB, McMahon GM, Waikar SS. Incidence of Hyponatremia in Patients With Indwelling Peritoneal Catheters for Drainage of Malignant Ascites. JAMA Netw Open. 2020 10 01; 3(10):e2017859.View Related Profiles.

Verma, Ashish
Mount, David Bruce
Waikar, Sushrut

PMID: 33104204; PMCID: PMC7588930; DOI: 10.1001/jamanetworkopen.2020.17859;

Boocock J, Leask M, Okada Y, Matsuo H, Kawamura Y, Shi Y, Li C, Mount DB, Mandal AK, Wang W, Cadzow M, Gosling AL, Major TJ, Horsfield JA, Choi HK, Fadason T, O'Sullivan J, Stahl EA, Merriman TR. Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control. Hum Mol Genet. 2020 04 15; 29(6):923-943. PMID: 31985003

Gupta S, McMahon GM, Motwani SS, Mount DB, Waikar SS. "Pleurex Desalination" in Malignancy-related Ascites: A Novel Mechanism of Hyponatremia. Am J Clin Oncol. 2020 01; 43(1):14-19.View Related Profiles.

Mount, David Bruce
Waikar, Sushrut

PMID: 31592807; PMCID: PMC6917883; DOI: 10.1097/COC.0000000000000618;

Mandal AK, Mount DB. Interaction Between ITM2B and GLUT9 Links Urate Transport to Neurodegenerative Disorders. Front Physiol. 2019; 10:1323. PMID: 31695625; PMCID: PMC6818471; DOI: 10.3389/fphys.2019.01323;

Mendu ML, Ahmed S, Maron JK, Rao SK, Chaguturu SK, May MF, Mutter WP, Burdge KA, Steele DJR, Mount DB, Waikar SS, Weilburg JB, Sequist TD. Development of an electronic health record-based chronic kidney disease registry to promote population health management. BMC Nephrol. 2019 03 01; 20(1):72.View Related Profiles.

Mount, David Bruce
Waikar, Sushrut

PMID: 30823871; PMCID: PMC6397481; DOI: 10.1186/s12882-019-1260-y;

Johnson RJ, Bakris GL, Borghi C, Chonchol MB, Feldman D, Lanaspa MA, Merriman TR, Moe OW, Mount DB, Sanchez Lozada LG, Stahl E, Weiner DE, Chertow GM. Hyperuricemia, Acute and Chronic Kidney Disease, Hypertension, and Cardiovascular Disease: Report of a Scientific Workshop Organized by the National Kidney Foundation. Am J Kidney Dis. 2018 06; 71(6):851-865. PMID: 29496260; PMCID: PMC7286363; DOI: 10.1053/j.ajkd.2017.12.009;

Soucek DJ, Mount DR, Dickinson A, Hockett JR. Influence of dilution water ionic composition on acute major ion toxicity to the mayfly Neocloeon triangulifer. Environ Toxicol Chem. 2018 05; 37(5):1330-1339. PMID: 29297606; PMCID: PMC6034637; DOI: 10.1002/etc.4072;

Tanner C, Boocock J, Stahl EA, Dobbyn A, Mandal AK, Cadzow M, Phipps-Green AJ, Topless RK, Hindmarsh JH, Stamp LK, Dalbeth N, Choi HK, Mount DB, Merriman TR. Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Maori and Pacific Men. Arthritis Rheumatol. 2017 07; 69(7):1461-1469. PMID: 28371506; PMCID: PMC5984252; DOI: 10.1002/art.40110;

Mandal AK, Mercado A, Foster A, Zandi-Nejad K, Mount DB. Uricosuric targets of tranilast. Pharmacol Res Perspect. 2017 Apr; 5(2):e00291. PMID: 28357121; PMCID: PMC5368959; DOI: 10.1002/prp2.291;

Leaf DE, Cheng XS, Sanders JL, Mendu M, Schiff GD, Mount DB, Bazari H. An electronic alert to decrease Kayexalate ordering. Ren Fail. 2016 Nov; 38(10):1752-1754. PMID: 27183825; PMCID: PMC5114173; DOI: 10.1080/0886022X.2016.1185353;

Muhsin SA, Mount DB. Diagnosis and treatment of hypernatremia. Best Pract Res Clin Endocrinol Metab. 2016 03; 30(2):189-203. PMID: 27156758

Mandal AK, Mount DB. The molecular physiology of uric acid homeostasis. Annu Rev Physiol. 2015; 77:323-45. PMID: 25422986

Mount DB. Thick ascending limb of the loop of Henle. Clin J Am Soc Nephrol. 2014 Nov 07; 9(11):1974-86. PMID: 25318757; PMCID: PMC4220766; DOI: 10.2215/CJN.04480413;

Toka HR, Genovese G, Mount DB, Pollak MR, Curhan GC. Frequency of rare allelic variation in candidate genes among individuals with low and high urinary calcium excretion. PLoS One. 2013; 8(8):e71885. PMID: 23991001; PMCID: PMC3753300; DOI: 10.1371/journal.pone.0071885;

Toka HR, Yang J, Zera CA, Duffield JS, Pollak MR, Mount DB. Pregnancy-associated polyuria in familial renal glycosuria. Am J Kidney Dis. 2013 Dec; 62(6):1160-4. PMID: 23871407

Mount DB. The kidney in hyperuricemia and gout. Curr Opin Nephrol Hypertens. 2013 Mar; 22(2):216-23. PMID: 23318701

Toka HR, Al-Romaih K, Koshy JM, DiBartolo S, Kos CH, Quinn SJ, Curhan GC, Mount DB, Brown EM, Pollak MR. Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria. J Am Soc Nephrol. 2012 Nov; 23(11):1879-90. PMID: 22997254; PMCID: PMC3482734; DOI: 10.1681/ASN.2012030323;

Reginato AM, Mount DB, Yang I, Choi HK. The genetics of hyperuricaemia and gout. Nat Rev Rheumatol. 2012 Oct; 8(10):610-21.View Related Profiles.

Mount, David Bruce
Choi, Hyon

PMID: 22945592; PMCID: PMC3645862; DOI: 10.1038/nrrheum.2012.144;

Acton BA, Mahadevan V, Mercado A, Uvarov P, Ding Y, Pressey J, Airaksinen MS, Mount DB, Woodin MA. Hyperpolarizing GABAergic transmission requires the KCC2 C-terminal ISO domain. J Neurosci. 2012 Jun 20; 32(25):8746-51. PMID: 22723714; PMCID: PMC3395202; DOI: 10.1523/JNEUROSCI.6089-11.2012;

Hui JY, Choi JW, Mount DB, Zhu Y, Zhang Y, Choi HK. The independent association between parathyroid hormone levels and hyperuricemia: a national population study. Arthritis Res Ther. 2012; 14(2):R56.View Related Profiles.

Mount, David Bruce
Choi, Hyon
Zhang, Yuqing

PMID: 22405053; PMCID: PMC3446422; DOI: 10.1186/ar3769;

Hamburger M, Baraf HS, Adamson TC, Basile J, Bass L, Cole B, Doghramji PP, Guadagnoli GA, Hamburger F, Harford R, Lieberman JA, Mandel DR, Mandelbrot DA, McClain BP, Mizuno E, Morton AH, Mount DB, Pope RS, Rosenthal KG, Setoodeh K, Skosey JL, Edwards NL. 2011 Recommendations for the diagnosis and management of gout and hyperuricemia. Postgrad Med. 2011 Nov; 123(6 Suppl 1):3-36. PMID: 22156509

Hamburger M, Baraf HS, Adamson TC, Basile J, Bass L, Cole B, Doghramji PP, Guadagnoli GA, Hamburger F, Harford R, Lieberman JA, Mandel DR, Mandelbrot DA, McClain BP, Mizuno E, Morton AH, Mount DB, Pope RS, Rosenthal KG, Setoodeh K, Skosey JL, Edwards NL. 2011 recommendations for the diagnosis and management of gout and hyperuricemia. Phys Sportsmed. 2011 Nov; 39(4):98-123. PMID: 22293773

Taylor EN, Stampfer MJ, Mount DB, Curhan GC. DASH-style diet and 24-hour urine composition. Clin J Am Soc Nephrol. 2010 Dec; 5(12):2315-22. PMID: 20847091; PMCID: PMC2994094; DOI: 10.2215/CJN.04420510;

Choi HK, Zhu Y, Mount DB. Genetics of gout. Curr Opin Rheumatol. 2010 Mar; 22(2):144-51.View Related Profiles.

Mount, David Bruce
Choi, Hyon

PMID: 20110790; DOI: 10.1097/BOR.0b013e32833645e8;

Hekmat-Scafe DS, Mercado A, Fajilan AA, Lee AW, Hsu R, Mount DB, Tanouye MA. Seizure sensitivity is ameliorated by targeted expression of K+-Cl- cotransporter function in the mushroom body of the Drosophila brain. Genetics. 2010 Jan; 184(1):171-83. PMID: 19884312; PMCID: PMC2815914; DOI: 10.1534/genetics.109.109074;

Waikar SS, Mount DB, Curhan GC. Mortality after hospitalization with mild, moderate, and severe hyponatremia. Am J Med. 2009 Sep; 122(9):857-65.View Related Profiles.

Mount, David Bruce
Waikar, Sushrut

PMID: 19699382; PMCID: PMC3033702; DOI: 10.1016/j.amjmed.2009.01.027;

Mount DB, Krahn TA. Hyponatremia: case vignettes. Semin Nephrol. 2009 May; 29(3):300-17. PMID: 19523576

Mount DB. The brain in hyponatremia: both culprit and victim. Semin Nephrol. 2009 May; 29(3):196-215. PMID: 19523569

Sindic A, Chang MH, Mount DB, Romero MF. Renal physiology of SLC26 anion exchangers. Curr Opin Nephrol Hypertens. 2007 Sep; 16(5):484-90. PMID: 17693766

Mount DB. Collectrin and the kidney. Curr Opin Nephrol Hypertens. 2007 Sep; 16(5):427-9. PMID: 17693757

Mount DB, Kwon CY, Zandi-Nejad K. Renal urate transport. Rheum Dis Clin North Am. 2006 May; 32(2):313-31, vi. PMID: 16716882

Taylor EN, Mount DB, Forman JP, Curhan GC. Association of prevalent hypertension with 24-hour urinary excretion of calcium, citrate, and other factors. Am J Kidney Dis. 2006 May; 47(5):780-9.View Related Profiles.

Mount, David Bruce
Forman, John

PMID: 16632016

Mercado A, Broumand V, Zandi-Nejad K, Enck AH, Mount DB. A C-terminal domain in KCC2 confers constitutive K+-Cl- cotransport. J Biol Chem. 2006 Jan 13; 281(2):1016-26. PMID: 16291749

Choi HK, Mount DB, Reginato AM. Pathogenesis of gout. Ann Intern Med. 2005 Oct 4; 143(7):499-516.View Related Profiles.

Mount, David Bruce
Choi, Hyon

PMID: 16204163

Mount DB. Molecular physiology and the four-component model of renal urate transport. Curr Opin Nephrol Hypertens. 2005 Sep; 14(5):460-3. PMID: 16046905

Mercado A, Vázquez N, Song L, Cortés R, Enck AH, Welch R, Delpire E, Gamba G, Mount DB. NH2-terminal heterogeneity in the KCC3 K+-Cl- cotransporter. Am J Physiol Renal Physiol. 2005 Dec; 289(6):F1246-61. PMID: 16048901

Mount DB. Novel physiology for an orphan transporter. Curr Opin Nephrol Hypertens. 2004 Sep; 13(5):521-3. PMID: 15300158

Mercado A, Gamba G, Mount DB. Molecular physiology of mammalian K(+)-Cl- cotransporters. Adv Exp Med Biol. 2004; 559:29-41. PMID: 18727225

Mercado A, Mount DB, Gamba G. Electroneutral cation-chloride cotransporters in the central nervous system. Neurochem Res. 2004 Jan; 29(1):17-25. PMID: 14992262

Mount DB, Romero MF. The SLC26 gene family of multifunctional anion exchangers. Pflugers Arch. 2004 Feb; 447(5):710-21. PMID: 12759755

Gallazzini M, Attmane-Elakeb A, Mount DB, Hebert SC, Bichara M. Regulation by glucocorticoids and osmolality of expression of ROMK (Kir 1.1), the apical K channel of thick ascending limb. Am J Physiol Renal Physiol. 2003 May; 284(5):F977-86. PMID: 12540364

Mount DB, Gamba G. Renal potassium-chloride cotransporters. Curr Opin Nephrol Hypertens. 2001 Sep; 10(5):685-91. PMID: 11496065

Liu H, Mount DB, Nasjletti A, Wang W. Carbon monoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb. J Clin Invest. 1999 Apr; 103(7):963-70. PMID: 10194468

Attmane-Elakeb A, Mount DB, Sibella V, Vernimmen C, Hebert SC, Bichara M. Stimulation by in vivo and in vitro metabolic acidosis of expression of rBSC-1, the Na+-K+(NH4+)-2Cl- cotransporter of the rat medullary thick ascending limb. J Biol Chem. 1998 Dec 11; 273(50):33681-91. PMID: 9837954

Luyckx VA, Goda FO, Mount DB, Nishio T, Hall A, Hebert SC, Hammond TG, Yu AS. Intrarenal and subcellular localization of rat CLC5. Am J Physiol. 1998 11; 275(5):F761-9. PMID: 9815133

Kaplan MR, Mount DB, Delpire E. Molecular mechanisms of NaCl cotransport. Annu Rev Physiol. 1996; 58:649-68. PMID: 8815813

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 61 publications over 24 distinct years, with a maximum of 7 publications in 2020

Bar chart showing 61 publications over 24 distinct years, with a maximum of 7 publications in 2020

Year	Publications
1996	1
1998	2
1999	1
2001	1
2003	2
2004	3
2005	4
2006	2
2007	2
2009	4
2010	2
2011	2
2012	4
2013	3
2014	2
2016	2
2017	2
2018	2
2019	2
2020	7
2021	5
2022	2
2023	2
2024	2

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