Nicholas A. Bosch, MD, MSc
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, New York Medical College
MS, Boston University School of Public Health
BS, University of California, Davis
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ORCID ORCID Icon : 0000-0001-7161-5254



Dr. Bosch is a health services researcher, epidemiologist, and critical care physician specializing in leveraging health services, quasi-experimental and causal-inference methods to inform and optimize the care of patients with critical illness. His research interests include learning health systems, sepsis, cardiovascular and endocrine disease during critical illness, substance use disorders in the ICU, and acute respiratory distress syndrome.


A Learning Health System Approach to Improve the Effectiveness of Blood Transfusions during Septic Shock
08/15/2024 - 07/31/2029 (PI)
NIH/National Heart, Lung, and Blood Institute
1K23HL173709-01

Improving the Effective Use of Blood Transfusions During Critical Illness for Patients with Cardiovascular Disease
04/01/2024 - 03/31/2027 (PI)
American Heart Association


The Relationship Between Type of Opioid Used During Critical Illness and Transition to Chronic Pain
09/01/2021 - 08/31/2024 (Subcontract PI)
Sunnybrook Research Institute Dept of Defense


Normalizing vasopressor dose to standardize vasopressors practice in septic shock
02/15/2020 - 06/27/2021 (PI)
NIH/National Institute of General Medical Sciences
5F32GM133061-02



Title

A Learning Health System Approach to Identify the Optimal Use of Secondary Vasopressors during Septic
04/01/2022 - 03/01/2024 (PI)
NIH/National Center for Advancing Translational Sciences
KL2TR001411


Yr Title Project-Sub Proj Pubs
2024 A Learning Health System Approach to Improve the Effectiveness of Blood Transfusions during Septic Shock 1K23HL173709-01
2021 Normalizing vasopressor dose to standardize vasopressors practice in septic shock 5F32GM133061-02
2019 Normalizing vasopressor dose to standardize vasopressors practice in septic shock 1F32GM133061-01

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Luo J, Pavlov I, Tavernier E, Perez Y, Kharat A, McNicholas B, Roca O, Vines DL, Ibarra-Estrada M, Alhazzani W, Lewis K, Simpson SQ, Rampon G, Liu L, Sun Q, Qiu H, Yang Y, Lapadula G, Qian ET, Gatto CL, Rice TW, Parhar KKS, Weatherald J, Walkey AJ, Bosch NA, Nay MA, Boulain T, Fossat G, Harris TRE, Thwaites CL, Phong NT, Bonfanti P, Yarahmadi S, Hashemian SM, Jayakumar D, Taylor SP, Johnson SA, Guerin C, Laffey JG, Ehrmann S, Li J. Awake Prone Positioning in Adults With COVID-19: An Individual Participant Data Meta-Analysis. JAMA Intern Med. 2025 May 01; 185(5):572-581.View Related Profiles. PMID: 40063016; PMCID: PMC11894540; DOI: 10.1001/jamainternmed.2025.0011;
     
  2. Mohanty A, Austad K, Bosch NA, Long MT, Nolen-Doerr E, Walkey AJ, Drainoni ML, Rizo I, Fantasia KL. Assessing Clinician Engagement with a Passive Clinical Decision Support System for Liver Fibrosis Risk Stratification in a Weight Management Clinic. Endocr Pract. 2025 Apr 25.View Related Profiles. PMID: 40288606
     
  3. Bosch NA, Wilson KC, Law AC. Are Procalcitonin Measures a Reliable Predictor of Stopping Antibiotics Among Patients With Sepsis? JAMA. 2025 Apr 14.View Related Profiles. PMID: 40227721
     
  4. Bosch NA. Blood Transfusion During Critical Illness, Not Just a Reflex Response to Low Hemoglobin Concentration. Crit Care Med. 2025 Jun 01; 53(6):e1317-e1319. PMID: 40208006
     
  5. Pang B, Kearney CM, Law AC, Bosch NA. Trends in the Treatment of Allergic Bronchopulmonary Aspergillosis. Ann Am Thorac Soc. 2025 Apr; 22(4):620-623.View Related Profiles. PMID: 39700483; PMCID: PMC12005012; DOI: 10.1513/AnnalsATS.202403-306RL;
     
  6. Dobie A, Shen B, Homer-Bouthiette C, Shankar D, Pang B, Law A, Bosch NA. Practice Pattern Variation in Management of Severe Acute Asthma Among Mechanically Ventilated Patients in Pediatric Versus Adult ICUs. Crit Care Explor. 2025 Apr 01; 7(4):e1233.View Related Profiles. PMID: 40126920; PMCID: PMC11936554; DOI: 10.1097/CCE.0000000000001233;
     
  7. Bosch NA. Toward Optimizing Short-Acting Beta-Blockers in Septic Shock. Crit Care Med. 2025 May 01; 53(5):e1160-e1162. PMID: 40099923
     
  8. Kothari OA, Stone J, Manivannan A, Segarra-Concepcion A, Ferri GM, Ganti R, Gurnani SD, Gurijala N, Toro C, Bosch NA, Claudel SE. Statin Use and Cardiovascular Risk in Young Adults in the United States. Am J Prev Med. 2025 May; 68(5):1028-1031.View Related Profiles. PMID: 39922395; DOI: 10.1016/j.amepre.2025.02.001;
     
  9. Carr JR, Locke B, Patel JJ, Peltan ID, Brown SM, Bosch NA, Law AC. Use of High-Dose Hydroxocobalamin for Septic Shock. Chest. 2025 Jan 24.View Related Profiles. PMID: 39864505
     
  10. Barnes SJ, Na Y, Drainoni ML, Linas BA, Bosch NA, Tamlyn AL. Barriers and facilitators to conducting human subjects research at a safety net institution from the perspective of researchers. PLoS One. 2025; 20(1):e0313530.View Related Profiles. PMID: 39775250; PMCID: PMC11709291; DOI: 10.1371/journal.pone.0313530;
     
Showing 10 of 95 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 95 publications over 10 distinct years, with a maximum of 23 publications in 2024

YearPublications
20141
20151
20181
20193
20206
202112
202216
202322
202423
202510


Lactated Ringer Solution Better Than Normal Saline for Sickle Cell Pain Crises

Health Day 9/17/2024

Better outcomes with lactated Ringer’s in vaso-occlusive crises

Sickle Cell Anemia News 9/12/2024

Study Supports Lactated Ringer Solution for Fluid Resuscitation in SCD

Medpage Today 9/9/2024

Hydrocortisone Plus Fludrocortisone Superior for Septic Shock

Health Day 4/13/2023

Combo of two steroids may reduce death risk for people with sepsis

UPI 3/30/2023

Combo Steroid Treatment May Work Best When Sepsis Strikes

HealthDay 3/29/2023

Combo Steroid Treatment May Work Best When Sepsis Strikes

US News and World Report 3/29/2023

Are Covid vaccine mandates ethical? Here’s what medical experts think

CNBC 11/24/2021

Vaccine panel recommends J&J boosters after data says vaccine's effectiveness has 'headroom to improve': Live COVID-19 updates

USA Today 11/16/2021

Have vaccine lotteries worked? Studies so far show mixed results

Politifact 8/22/2021

Trending Clinical Topic: Prone Positioning in COVID-19

Medscape 10/9/2020

Experts Divided on Awake Prone Position for Severe COVID-19

Medscape 9/18/2020

Could Flipping COVID-19 Patients Over Ease Breathing?

Futurity 4/27/2020

For COVID-19 Patients, Could Breathing Easier Be as Simple as Flipping Over?

Mirage News 4/18/2020

2025 American Society for Clinical Investigation (ASCI): Young Physician-Scientist Awards
2024-2027 American Heart Association: Career Development Award (24CDA1267699)
2024 CHEST: Best of CHEST: How We Escalate Vasopressor and Corticosteroid Therapy in Patients with Septic Shock
2024 American Thoracic Society: Clinical Year in Review, Sepsis: PMC10043800
2022 Boston University School of Medicine Department of Medicine : Robert Dawson Evans Quality Improvement Award
2022 Boston Medical Center: Top Faculty Excellence in Teaching
2022-2024 Boston University CTSI - NCATS: KL2 Career Development Award (1KL2TR001411)
2022-2024 Boston University Chobanian & Avedisian School of Medicine : Department of Medicine Career Investment Award
2011 New York Medical College: Gold Humanism Honor Society
2011 New York Medical College: Alpha Omega Alpha Honor Society
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Sepsis
Alcohol Withdrawal Syndrome
Health Services Research
Quasi-Experimental Studies
Acute Respiratory Distress Syndrome
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