Nicholas A. Bosch, MD, MSc
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, New York Medical College
MS, Boston University School of Public Health
BS, University of California, Davis
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ORCID ORCID Icon : 0000-0001-7161-5254



Dr. Bosch is a health services researcher, epidemiologist, and critical care physician specializing in leveraging health services, quasi-experimental and causal-inference methods to inform and optimize the care of patients with critical illness. His research interests include learning health systems, sepsis, cardiovascular and endocrine disease during critical illness, substance use disorders in the ICU, and acute respiratory distress syndrome.


A Learning Health System Approach to Improve the Effectiveness of Blood Transfusions during Septic Shock
08/15/2024 - 07/31/2029 (PI)
NIH/National Heart, Lung, and Blood Institute
1K23HL173709-01

Improving the Effective Use of Blood Transfusions During Critical Illness for Patients with Cardiovascular Disease
04/01/2024 - 03/31/2027 (PI)
American Heart Association


The Relationship Between Type of Opioid Used During Critical Illness and Transition to Chronic Pain
09/01/2021 - 08/31/2024 (Subcontract PI)
Sunnybrook Research Institute Dept of Defense


Normalizing vasopressor dose to standardize vasopressors practice in septic shock
02/15/2020 - 06/27/2021 (PI)
NIH/National Institute of General Medical Sciences
5F32GM133061-02



Title

A Learning Health System Approach to Identify the Optimal Use of Secondary Vasopressors during Septic
04/01/2022 - 03/01/2024 (PI)
NIH/National Center for Advancing Translational Sciences
KL2TR001411


Yr Title Project-Sub Proj Pubs
2024 A Learning Health System Approach to Improve the Effectiveness of Blood Transfusions during Septic Shock 1K23HL173709-01
2021 Normalizing vasopressor dose to standardize vasopressors practice in septic shock 5F32GM133061-02
2019 Normalizing vasopressor dose to standardize vasopressors practice in septic shock 1F32GM133061-01

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Luo J, Pavlov I, Tavernier E, Perez Y, Kharat A, McNicholas B, Roca O, Vines DL, Ibarra-Estrada M, Alhazzani W, Lewis K, Simpson SQ, Rampon G, Liu L, Sun Q, Qiu H, Yang Y, Lapadula G, Qian ET, Gatto CL, Rice TW, Parhar KKS, Weatherald J, Walkey AJ, Bosch NA, Nay MA, Boulain T, Fossat G, Harris TRE, Thwaites CL, Phong NT, Bonfanti P, Yarahmadi S, Hashemian SM, Jayakumar D, Taylor SP, Johnson SA, Guerin C, Laffey JG, Ehrmann S, Li J. Awake Prone Positioning in Adults With COVID-19: An Individual Participant Data Meta-Analysis. JAMA Intern Med. 2025 Mar 10. PMID: 40063016; PMCID: PMC11894540; DOI: 10.1001/jamainternmed.2025.0011;
     
  2. Kothari OA, Stone J, Manivannan A, Segarra-Concepcion A, Ferri GM, Ganti R, Gurnani SD, Gurijala N, Toro C, Bosch NA, Claudel SE. Statin Use and Cardiovascular Risk in Young Adults in the United States. Am J Prev Med. 2025 Feb 06.View Related Profiles. PMID: 39922395; DOI: 10.1016/j.amepre.2025.02.001;
     
  3. Carr JR, Locke B, Patel JJ, Peltan ID, Brown SM, Bosch NA, Law AC. Use of High-Dose Hydroxocobalamin for Septic Shock. Chest. 2025 Jan 24.View Related Profiles. PMID: 39864505
     
  4. Barnes SJ, Na Y, Drainoni ML, Linas BA, Bosch NA, Tamlyn AL. Barriers and facilitators to conducting human subjects research at a safety net institution from the perspective of researchers. PLoS One. 2025; 20(1):e0313530.View Related Profiles. PMID: 39775250; PMCID: PMC11709291; DOI: 10.1371/journal.pone.0313530;
     
  5. Pang B, Kearney CM, Law AC, Bosch NA. Trends in the Treatment of Allergic Bronchopulmonary Aspergillosis. Ann Am Thorac Soc. 2024 Dec 19.View Related Profiles. PMID: 39700483
     
  6. Wunsch H, Bosch NA, Law AC, Vail EA, Hua M, Shen BH, Lindenauer PK, Juurlink DN, Walkey AJ, Gershengorn HB. Evaluation of Etomidate Use and Association with Mortality Compared with Ketamine among Critically Ill Patients. Am J Respir Crit Care Med. 2024 Nov 15; 210(10):1243-1251.View Related Profiles. PMID: 39173173
     
  7. Sangani R, Bosch NA, Govender P, Scarpato B, Walkey AJ, Newman J, Law AC, Gillmeyer KR, Shankar DA. Sarcoidosis Treatment Patterns in the United States: 2016-2022. Chest. 2024 Nov 09.View Related Profiles. PMID: 39522595
     
  8. Alwang AK, Law AC, Klings ES, Cohen RT, Bosch NA. Lactated Ringer vs Normal Saline Solution During Sickle Cell Vaso-Occlusive Episodes. JAMA Intern Med. 2024 Nov 01; 184(11):1365-1372.View Related Profiles. PMID: 39250114; PMCID: PMC11385329; DOI: 10.1001/jamainternmed.2024.4428;
     
  9. Bosch NA, Law AC, Fawzy A, Iwashyna TJ. Prevalence of Inpatient Pulse Oximetry in Operative and Nonoperative Settings: A Multicenter Study. CHEST Crit Care. 2024 Dec; 2(4).View Related Profiles. PMID: 39741966; PMCID: PMC11687362; DOI: 10.1016/j.chstcc.2024.100104;
     
  10. Teja B, Pereira TV, Law AC, Mazer CD, Bosch NA. Publisher Correction: Effectiveness of fludrocortisone and hydrocortisone versus hydrocortisone alone in septic shock with and without pneumonia. Intensive Care Med. 2024 Oct; 50(10):1727.View Related Profiles. PMID: 39102029
     
Showing 10 of 90 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 90 publications over 10 distinct years, with a maximum of 24 publications in 2024

YearPublications
20141
20151
20181
20193
20206
202112
202216
202322
202424
20254


Lactated Ringer Solution Better Than Normal Saline for Sickle Cell Pain Crises

Health Day 9/17/2024

Better outcomes with lactated Ringer’s in vaso-occlusive crises

Sickle Cell Anemia News 9/12/2024

Study Supports Lactated Ringer Solution for Fluid Resuscitation in SCD

Medpage Today 9/9/2024

Hydrocortisone Plus Fludrocortisone Superior for Septic Shock

Health Day 4/13/2023

Combo of two steroids may reduce death risk for people with sepsis

UPI 3/30/2023

Combo Steroid Treatment May Work Best When Sepsis Strikes

HealthDay 3/29/2023

Combo Steroid Treatment May Work Best When Sepsis Strikes

US News and World Report 3/29/2023

Are Covid vaccine mandates ethical? Here’s what medical experts think

CNBC 11/24/2021

Vaccine panel recommends J&J boosters after data says vaccine's effectiveness has 'headroom to improve': Live COVID-19 updates

USA Today 11/16/2021

Have vaccine lotteries worked? Studies so far show mixed results

Politifact 8/22/2021

Trending Clinical Topic: Prone Positioning in COVID-19

Medscape 10/9/2020

Experts Divided on Awake Prone Position for Severe COVID-19

Medscape 9/18/2020

Could Flipping COVID-19 Patients Over Ease Breathing?

Futurity 4/27/2020

For COVID-19 Patients, Could Breathing Easier Be as Simple as Flipping Over?

Mirage News 4/18/2020

2025 American Society for Clinical Investigation (ASCI): Young Physician-Scientist Awards
2024-2027 American Heart Association: Career Development Award (24CDA1267699)
2024 CHEST: Best of CHEST: How We Escalate Vasopressor and Corticosteroid Therapy in Patients with Septic Shock
2024 American Thoracic Society: Clinical Year in Review, Sepsis: PMC10043800
2022 Boston University School of Medicine Department of Medicine : Robert Dawson Evans Quality Improvement Award
2022 Boston Medical Center: Top Faculty Excellence in Teaching
2022-2024 Boston University CTSI - NCATS: KL2 Career Development Award (1KL2TR001411)
2022-2024 Boston University Chobanian & Avedisian School of Medicine : Department of Medicine Career Investment Award
2011 New York Medical College: Gold Humanism Honor Society
2011 New York Medical College: Alpha Omega Alpha Honor Society
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Sepsis
Alcohol Withdrawal Syndrome
Health Services Research
Quasi-Experimental Studies
Acute Respiratory Distress Syndrome
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