Christopher Chen, MD, PhD
Professor
Boston University College of Engineering
Dept of Biomedical Engineering

MD, Harvard University
PhD, Massachusetts Institute of Technology
MS, Massachusetts Institute of Technology





Science and Technology Center for Engineering Mechano-Biology
10/01/2016 - 09/30/2026 (Subcontract PI)
The Trustees of the University of Pennsylvania National Science Fdn
CMMI-1548571

Defining Genetic Architecture and Pathways of DCM
02/17/2021 - 01/31/2025 (Subcontract PI)
Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard NIH NHLBI
2R01HL080494-13

Novel strategies to understand, predict, and prevent vascular toxicity of targeted CML therapies
01/01/2021 - 12/31/2024 (Subcontract PI)
Tufts - New England Medical Center NIH NHLBI
1R01HL155078-01

Engineering Branching Networks Through Synthetic Turing Morphogen Circuits
12/10/2021 - 12/09/2024 (Multi-PI)
Allen Institute d/b/a The Paul G. Allen Frontiers Group


Synthetic Biology and Biotechnology (SB2) Predoctoral Training Program
07/01/2019 - 06/30/2024 (Multi-PI)
NIH/National Institute of General Medical Sciences
5T32GM130546-03

Engineering high density functional vascular, lymphatic, and ductal trees
04/01/2021 - 03/31/2024 (Subcontract PI)
Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Wellcome Leap


Engineering high density functional vascular, lymphatic, and ductal trees
04/01/2021 - 03/31/2024 (Subcontract PI)
Hansjorg Wyss Institute for Biologically Inspired Engineering at Harvard Wellcome Leap


Local Regulation of Angiogenesis by Microenvironment
05/01/2020 - 01/31/2024 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
5R01EB000262-21

Notch signaling and adhesion regulation
06/01/2019 - 03/31/2023 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL147585-03

Geometric and mechanical patterning of hierarchical vascular networks
10/01/2018 - 09/30/2022 (PI)
United States - Israel Binational Science Foundation (Israel)


Showing 10 of 61 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2021 Local Regulation of Angiogenesis by Microenvironment 5R01EB000262-21 96
2021 Synthetic Biology and Biotechnology (SB2) Predoctoral Training Program 5T32GM130546-03
2021 Notch signaling and adhesion regulation 5R01HL147585-03
2021 Defining Genetic Architecture and Pathways of DCM 2R01HL080494-13 61
2020 Local Regulation of Angiogenesis by Microenvironment 2R01EB000262-20 96
2020 Synthetic Biology and Biotechnology (SB2) Predoctoral Training Program 5T32GM130546-02
2020 Notch signaling and adhesion regulation 5R01HL147585-02
2019 Synthetic Biology and Biotechnology (SB2) Predoctoral Training Program 1T32GM130546-01
2019 Notch signaling and adhesion regulation 1R01HL147585-01
2019 Defining Genetic Architecture and Pathways of DCM 5R01HL080494-12 61
Showing 10 of 69 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Michas C, Karakan MÇ, Nautiyal P, Seidman JG, Seidman CE, Agarwal A, Ekinci K, Eyckmans J, White AE, Chen CS. Engineering a living cardiac pump on a chip using high-precision fabrication. Sci Adv. 2022 Apr 22; 8(16):eabm3791.View Related Profiles. PMID: 35452278; PMCID: PMC9032966; DOI: 10.1126/sciadv.abm3791;
     
  2. Sundaram S, Chen CS. Next-generation engineered microsystems for cell biology: a systems-level roadmap. Trends Cell Biol. 2022 Jun; 32(6):490-500. PMID: 35105487
     
  3. Tefft JB, Bays JL, Lammers A, Kim S, Eyckmans J, Chen CS. Notch1 and Notch3 coordinate for pericyte-induced stabilization of vasculature. Am J Physiol Cell Physiol. 2022 02 01; 322(2):C185-C196.View Related Profiles. PMID: 34878922; PMCID: PMC8791789; DOI: 10.1152/ajpcell.00320.2021;
     
  4. Zhang K, Cloonan PE, Sundaram S, Liu F, Das SL, Ewoldt JK, Bays JL, Tomp S, Toepfer CN, Marsiglia JDC, Gorham J, Reichart D, Eyckmans J, Seidman JG, Seidman CE, Chen CS. Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization. Sci Adv. 2021 Oct 15; 7(42):eabh3995.View Related Profiles. PMID: 34652945; PMCID: PMC8519574; DOI: 10.1126/sciadv.abh3995;
     
  5. Jayne RK, Karakan MÇ, Zhang K, Pierce N, Michas C, Bishop DJ, Chen CS, Ekinci KL, White AE. Direct laser writing for cardiac tissue engineering: a microfluidic heart on a chip with integrated transducers. Lab Chip. 2021 05 04; 21(9):1724-1737. PMID: 33949395
     
  6. Zhou DW, Fernández-Yagüe MA, Holland EN, García AF, Castro NS, O'Neill EB, Eyckmans J, Chen CS, Fu J, Schlaepfer DD, García AJ. Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair. Nat Commun. 2021 04 21; 12(1):2359.View Related Profiles. PMID: 33883558; PMCID: PMC8060400; DOI: 10.1038/s41467-021-22602-5;
     
  7. Song J, Michas C, Chen CS, White AE, Grinstaff MW. Controlled Cell Alignment Using Two-Photon Direct Laser Writing-Patterned Hydrogels in 2D and 3D. Macromol Biosci. 2021 05; 21(5):e2100051.View Related Profiles. PMID: 33738917
     
  8. Tsang JM, Gritton HJ, Das SL, Weber TD, Chen CS, Han X, Mertz J. Fast, multiplane line-scan confocal microscopy using axially distributed slits. Biomed Opt Express. 2021 Mar 01; 12(3):1339-1350.View Related Profiles. PMID: 33796357; PMCID: PMC7984773; DOI: 10.1364/BOE.417286;
     
  9. Javor J, Ewoldt JK, Cloonan PE, Chopra A, Luu RJ, Freychet G, Zhernenkov M, Ludwig K, Seidman JG, Seidman CE, Chen CS, Bishop DJ. Probing the subcellular nanostructure of engineered human cardiomyocytes in 3D tissue. Microsyst Nanoeng. 2021; 7:10. PMID: 34567727; PMCID: PMC8433147; DOI: 10.1038/s41378-020-00234-x;
     
  10. Tefft JB, Chen CS, Eyckmans J. Reconstituting the dynamics of endothelial cells and fibroblasts in wound closure. APL Bioeng. 2021 Mar; 5(1):016102.View Related Profiles. PMID: 33511324; PMCID: PMC7817247; DOI: 10.1063/5.0028651;
     
Showing 10 of 58 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 58 publications over 16 distinct years, with a maximum of 8 publications in 2021

YearPublications
20031
20082
20091
20102
20112
20123
20134
20145
20154
20165
20176
20185
20195
20203
20218
20222

2019 The Charles DeLisi Lecture Award
2019 The Charles DeLisi Lecture Award
2019 The Biomedical Engineering Society Robert A. Pritzker Distinguished Lecture Award
2010 The George H. Heilmeier Faculty Award for Excellence in Researc
2006 MicroTAS: Scientific Advisory Board
2005 Biomedical Engineering Society: Scientific Advisory Board
2004 The Herbert W. Dickerman Award for Outstanding Contribution to Science
2003-2005 Defense Sciences Research Council: fellow
2002 The Mary Hulman George Award for Biomedical Research
2001-2002 SmallTalk: Scientific Committee Member
2000 Presidential Early Career Award for Scientists and Engineers
2000 Presidential Early Career Award for Scientists and Engineers
2000 Presidential Early Career Award for Scientists and Engineers
1999 ONR Young Investigator Award
1997 Angiogenesis Foundation Fellowship
1994-1995 Health Sciences and Technology Research Fund Award
1993-1997 Medical Engineering and Medical Physics Fellow
1991-1993 National Science Foundation Graduate Research Fellow
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36 Cummington St
Boston MA 02215
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