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PhD, Ranchi University
MS, Ranchi University
BS, Ranchi University

Research
Publications

BU Research
BMC Research

Developing a Predictive Biomarker for Topol Inhibitors
04/01/2011 - 03/31/2013 (PI)
Predictius Bioscience Inc.

To determine the synergistic effect of MLN9708 with irinotecan in solid tumor and use of a predictiv
01/27/2014 - 01/27/2016 (PI)
Millennium Pharmaceuticals Inc

Role of c-Met in SCLC and Potential for Novel Therapy
09/19/2008 - 02/28/2013 (PI)
Univ of Chicago NIH-NCI

Role of Neuroregulin/erbB Signaling in the Adult Heart
07/01/2006 - 06/30/2007 (PI)
Vanderbilt University Medical Center NIH-NHLBI
7 R01 HL068144

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Ando K, Hu Q, Fujimoto Y, Jogo T, Nakanishi R, Hisamatsu Y, Kimura Y, Oki E, Bharti A, Mori M. [The Efficacy of topo ?-pS10 Expression in Gastric Cancer as a Predictive Biomarker for Irinotecan Use]. Gan To Kagaku Ryoho. 2021 Mar; 48(3):331-335. PMID: 33790151

Ando K, Ozonoff A, Lee SY, Voisine M, Parker JT, Nakanishi R, Nishimura S, Yang J, Grace Z, Tran B, Diefenbach TJ, Maehara Y, Yasui H, Irino T, Salgia R, Terashima M, Gibbs P, Ramanathan RK, Oki E, Mori M, Kulke M, Hartshorn K, Bharti A. Multicohort Retrospective Validation of a Predictive Biomarker for Topoisomerase I Inhibitors. Clin Colorectal Cancer. 2021 06; 20(2):e129-e138.View Related Profiles.

Bharti, Ajit
Ozonoff, Alexander
Hartshorn, Kevan
Kulke, Matthew

PMID: 33731288

Matsuoka H, Ando K, Swayze EJ, Unan EC, Mathew J, Hu Q, Tsuda Y, Nakashima Y, Saeki H, Oki E, Bharti AK, Mori M. CTDSP1 inhibitor rabeprazole regulates DNA-PKcs dependent topoisomerase I degradation and irinotecan drug resistance in colorectal cancer. PLoS One. 2020; 15(8):e0228002.View Related Profiles.

Bharti, Ajit
Unan, Elizabeth

PMID: 32764831; DOI: 10.1371/journal.pone.0228002;

Ando K, Tohme YH, Srinivasiah A, Taylor-Parker J, Harrington Y, Shah AK, Oki E, Brahmandam M, Bharti AK. Developing a Phosphospecific IHC Assay as a Predictive Biomarker for Topoisomerase I Inhibitors. J Histochem Cytochem. 2018 08; 66(8):549-561.View Related Profiles.

Bharti, Ajit
Shah, Ankur

PMID: 29587004; DOI: 10.1369/0022155418766503;

Ando K, Shah AK, Sachdev V, Kleinstiver BP, Taylor-Parker J, Welch MM, Hu Y, Salgia R, White FM, Parvin JD, Ozonoff A, Rameh LE, Joung JK, Bharti AK. Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway. Oncotarget. 2017 Jul 04; 8(27):43733-43751.View Related Profiles.

Bharti, Ajit
Ozonoff, Alexander
Shah, Ankur
Rameh Plant, Lucia

PMID: 28415827; DOI: 10.18632/oncotarget.16376;

Raina D, Agarwal P, Lee J, Bharti A, McKnight CJ, Sharma P, Kharbanda S, Kufe D. Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target. PLoS One. 2015; 10(8):e0135156.View Related Profiles.

Bharti, Ajit
McKnight, C.

PMID: 26267657; PMCID: PMC4534190; DOI: 10.1371/journal.pone.0135156;

Rolle CE, Kanteti R, Surati M, Nandi S, Dhanasingh I, Yala S, Tretiakova M, Arif Q, Hembrough T, Brand TM, Wheeler DL, Husain AN, Vokes EE, Bharti A, Salgia R. Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer. Mol Cancer Ther. 2014 Mar; 13(3):576-84. PMID: 24327519; DOI: 10.1158/1535-7163.MCT-13-0109;

Icli B, Bharti A, Pentassuglia L, Peng X, Sawyer DB. ErbB4 localization to cardiac myocyte nuclei, and its role in myocyte DNA damage response. Biochem Biophys Res Commun. 2012 Feb 3; 418(1):116-21. PMID: 22244893; PMCID: PMC3273580; DOI: 10.1016/j.bbrc.2011.12.144;

Tamayo AG, Slater L, Taylor-Parker J, Bharti A, Harrison R, Hung DT, Murphy JR. GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro. Mol Microbiol. 2011 Sep; 81(5):1390-401.View Related Profiles.

Bharti, Ajit
Murphy, John
Harrison, Robert

PMID: 21797942; DOI: 10.1111/j.1365-2958.2011.07770.x;

Murshid A, Chou SD, Prince T, Zhang Y, Bharti A, Calderwood SK. Protein kinase A binds and activates heat shock factor 1. PLoS One. 2010; 5(11):e13830. PMID: 21085490; PMCID: PMC2976705; DOI: 10.1371/journal.pone.0013830;

Showing 10 of 28 results. Show More

Shah A, Singh H, Sachdev V, Lee J, Yotsukura S, Salgia R, Bharti A. DIFFERENTIAL SERUM LEVEL OF SPECIFIC HAPTOGLOBIN ISOFORMS IN SMALL CELL LUNG CANCER. Curr Proteomics. 2010 Apr 01; 7(1):49-65.View Related Profiles.

Bharti, Ajit
Shah, Ankur

PMID: 20526421

Chitalia VC, Foy RL, Bachschmid MM, Zeng L, Panchenko MV, Zhou MI, Bharti A, Seldin DC, Lecker SH, Dominguez I, Cohen HT. Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. Nat Cell Biol. 2008 Oct; 10(10):1208-16.View Related Profiles.

Bharti, Ajit
Seldin, David
Cohen, Herbert
Dominguez, Maria
Panchenko, Maria
Bachschmid, Markus
Zhou, Mina
Chitalia, Vipul

PMID: 18806787; PMCID: PMC2830866; DOI: 10.1038/ncb1781;

Tamayo AG, Bharti A, Trujillo C, Harrison R, Murphy JR. COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro. Proc Natl Acad Sci U S A. 2008 Apr 1; 105(13):5254-9.View Related Profiles.

Bharti, Ajit
Murphy, John
Harrison, Robert

PMID: 18356299; PMCID: PMC2278175; DOI: 10.1073/pnas.0710100105;

Bharti A, Ma PC, Salgia R. Biomarker discovery in lung cancer--promises and challenges of clinical proteomics. Mass Spectrom Rev. 2007 May-Jun; 26(3):451-66. PMID: 17407130

Enomoto Y, Bharti A, Khaleque AA, Song B, Liu C, Apostolopoulos V, Xing PX, Calderwood SK, Gong J. Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells. J Immunol. 2006 Nov 1; 177(9):5946-55.View Related Profiles.

Bharti, Ajit
Gong, Jianlin

PMID: 17056519

Bausero MA, Bharti A, Page DT, Perez KD, Eng JW, Ordonez SL, Asea EE, Jantschitsch C, Kindas-Muegge I, Ciocca D, Asea A. Silencing the hsp25 gene eliminates migration capability of the highly metastatic murine 4T1 breast adenocarcinoma cell. Tumour Biol. 2006; 27(1):17-26. PMID: 16340246; PMCID: PMC1764206; DOI: 10.1159/000090152;

Ratts R, Trujillo C, Bharti A, vanderSpek J, Harrison R, Murphy JR. A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol. Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15635-40.View Related Profiles.

Bharti, Ajit
Murphy, John
Harrison, Robert

PMID: 16230620; PMCID: PMC1257389; DOI: 10.1073/pnas.0504937102;

Khaleque MA, Bharti A, Sawyer D, Gong J, Benjamin IJ, Stevenson MA, Calderwood SK. Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth. Oncogene. 2005 Sep 29; 24(43):6564-73.View Related Profiles.

Bharti, Ajit
Gong, Jianlin

PMID: 16007186

Bryan NS, Fernandez BO, Bauer SM, Garcia-Saura MF, Milsom AB, Rassaf T, Maloney RE, Bharti A, Rodriguez J, Feelisch M. Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues. Nat Chem Biol. 2005 Oct; 1(5):290-7. PMID: 16408059

Peng X, Guo X, Borkan SC, Bharti A, Kuramochi Y, Calderwood S, Sawyer DB. Heat shock protein 90 stabilization of ErbB2 expression is disrupted by ATP depletion in myocytes. J Biol Chem. 2005 Apr 1; 280(13):13148-52.View Related Profiles.

Bharti, Ajit
Borkan, Steven

PMID: 15671027

Raina D, Pandey P, Ahmad R, Bharti A, Ren J, Kharbanda S, Weichselbaum R, Kufe D. c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem. 2005 Mar 25; 280(12):11147-51. PMID: 15657060

Yu D, Khan E, Khaleque MA, Lee J, Laco G, Kohlhagen G, Kharbanda S, Cheng YC, Pommier Y, Bharti A. Phosphorylation of DNA topoisomerase I by the c-Abl tyrosine kinase confers camptothecin sensitivity. J Biol Chem. 2004 Dec 10; 279(50):51851-61. PMID: 15448168

Bharti A, Ma PC, Maulik G, Singh R, Khan E, Skarin AT, Salgia R. Haptoglobin alpha-subunit and hepatocyte growth factor can potentially serve as serum tumor biomarkers in small cell lung cancer. Anticancer Res. 2004 Mar-Apr; 24(2C):1031-8. PMID: 15154618

Maulik G, Bharti A, Khan E, Broderick RJ, Kijima T, Salgia R. Modulation of c-Kit/SCF pathway leads to alterations in topoisomerase-I activity in small cell lung cancer. J Environ Pathol Toxicol Oncol. 2004; 23(4):237-51. PMID: 15511212

Helmes M, Lim CC, Liao R, Bharti A, Cui L, Sawyer DB. Titin determines the Frank-Starling relation in early diastole. J Gen Physiol. 2003 Feb; 121(2):97-110. PMID: 12566538; PMCID: PMC2217323

Ma PC, Blaszkowsky L, Bharti A, Ladanyi A, Kraeft SK, Bruno A, Skarin AT, Chen LB, Salgia R. Circulating tumor cells and serum tumor biomarkers in small cell lung cancer. Anticancer Res. 2003 Jan-Feb; 23(1A):49-62. PMID: 12683352

Ren J, Datta R, Shioya H, Li Y, Oki E, Biedermann V, Bharti A, Kufe D. p73beta is regulated by protein kinase Cdelta catalytic fragment generated in the apoptotic response to DNA damage. J Biol Chem. 2002 Sep 13; 277(37):33758-65. PMID: 12097319

Li XG, Haluska P, Hsiang YH, Bharti AK, Kufe DW, Liu LF, Rubin EH. Involvement of amino acids 361 to 364 of human topoisomerase I in camptothecin resistance and enzyme catalysis. Biochem Pharmacol. 1997 Apr 04; 53(7):1019-27. PMID: 9174116

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

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