Expertise in molecular pathology.
Diversity, Equity, Inclusion and Accessibility
I am fully for diversity equity inclusion and accessibility (DEIA not only for supporting the idea but also showed the action that I am for it, support and do it. I believe these action and activities can build a better society and better BU.
I came along from a different country and culture environment to pursue a better career in medicine and research. Throughout 30 plus years training and working of my life at BUSM, I am better understood, equipped and benefit from practicing DEIA.
As a result, I actively engaged in DEIA activities and supporting the movement by my own action. In addition of doing everything helpful in my everyday activity, I also participate in network activities in groups like FSCN (faculty and staff of color community network: I am the treasurer of BU FSCN). I believe action is much more active and efficient than words along. I will consistently do what I thought was the right thing throughout my tenure of Boston University and beyond.
Member
Boston University
BU-BMC Cancer Center
Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
-
Yang S, Leone DA, Biswas A, Deng A, Jukic D, Singh R, Sundram U, Mahalingam M. Concordance of somatic mutation profiles (BRAF,NRAS, and TERT) and tumoral PD-L1 in matched primary cutaneous and metastatic melanoma samples. Hum Pathol. 2018 12; 82:206-214. PMID: 30120967
-
de la Cueva A, Emmerling M, Lim SL, Yang S, Trackman PC, Sonenshein GE, Kirsch KH. A polymorphism in the lysyl oxidase propeptide domain accelerates carcinogen-induced cancer. Carcinogenesis. 2018 07 03; 39(7):921-930.View Related Profiles. PMID: 29579155; PMCID: PMC6692853; DOI: 10.1093/carcin/bgy045;
-
-
Frydenlund N, Leone D, Yang S, Hoang MP, Deng A, Hernandez-Perez M, Singh R, Biswas A, Yaar R, Mahalingam M. Tumoral PD-L1 expression in desmoplastic melanoma is associated with depth of invasion, tumor-infiltrating CD8 cytotoxic lymphocytes and the mixed cytomorphological variant. Mod Pathol. 2017 Mar; 30(3):357-369. PMID: 28084337; DOI: 10.1038/modpathol.2016.210;
-
Josenia Tan, Antonio de las Morenas , Shi Yang and Huihong Xu. Comparison of the clinicopathologic features of solitary and multifocal papillary thyroid carcinoma and the utility of testing an additional tumor nodule for BRAFV600E in multifocal cases. J Mod Hum Pathol. 2017; 2(1):1-6. View Publication
-
Mitchell B, Leone D, Yang S, Khan A, Mahalingam M, Dhingra J. BRAF and epithelial-mesenchymal transition in papillary thyroid carcinoma - challenging the roles of Snail and E-Cadherin? Am J Transl Res. 2016; 8(11):5076-5086. PMID: 27904709; PMCID: PMC5126351
-
Yang S, Leone D, Frydenlund N, Hoang M, Deng A, Hernandez-Perez M, Biswas A, Singh R, Yaar R, Mahalingam M. Frequency of telomerase reverse transcripter promoter mutations in desmoplastic melanoma subtypes: analyses of 76 cases. Melanoma Res. 2016 Aug; 26(4):361-6. PMID: 27244099; DOI: 10.1097/CMR.0000000000000272;
-
Kadokura A, Frydenlund N, Leone DA, Yang S, Hoang MP, Deng A, Hernandez-Perez M, Biswas A, Singh R, Yaar R, Mahalingam M. Neurofibromin protein loss in desmoplastic melanoma subtypes: implicating NF1 allelic loss as a distinct genetic driver? Hum Pathol. 2016 Jul; 53:82-90. PMID: 26980030; DOI: 10.1016/j.humpath.2016.02.012;
-
Mitchell B, Leone DA, Feller JK, Yang S, Mahalingam M. BRAF and epithelial-mesenchymal transition in primary cutaneous melanoma: a role for Snail and E-cadherin? Hum Pathol. 2016 Jun; 52:19-27. PMID: 26980024; DOI: 10.1016/j.humpath.2015.12.030;
-
Showing 10 of 52 results.
Show More
-
-
-
-
Mitchell B, Leone D, Feller JK, Bondzie P, Yang S, Park HY, Mahalingam M. Correlation of chemokine receptor CXCR4 mRNA in primary cutaneous melanoma with established histopathologic prognosticators and the BRAF status. Melanoma Res. 2014 Dec; 24(6):621-5.View Related Profiles. PMID: 25211166; DOI: 10.1097/CMR.0000000000000120;
-
Aung PP, Leone D, Feller JK, Yang S, Hernandez M, Yaar R, Singh R, Helm T, Mahalingam M. Microvessel density, lymphovascular density, and lymphovascular invasion in primary cutaneous melanoma-correlation with histopathologic prognosticators and BRAF status. Hum Pathol. 2015 Feb; 46(2):304-12.View Related Profiles. PMID: 25537974; DOI: 10.1016/j.humpath.2014.11.006;
-
Aguilera P, Malvehy J, Carrera C, Palou J, Puig-Butillé JA, Alòs L, Badenas C, Puig S. Clinical and Histopathological Characteristics between Familial and Sporadic Melanoma in Barcelona, Spain. J Clin Exp Dermatol Res. 2014 Sep; 5(5):231. PMID: 25893138; PMCID: PMC4399806; DOI: 10.4172/2155-9554.1000231;
-
-
Mitchell B, Leone D, Feller K, Menon S, Bondzie P, Yang S, Park HY, Mahalingam M. Protein expression of the chemokine receptor CXCR4 and its ligand CXCL12 in primary cutaneous melanoma--biomarkers of potential utility? Hum Pathol. 2014 Oct; 45(10):2094-100.View Related Profiles. PMID: 25130395; DOI: 10.1016/j.humpath.2014.06.018;
-
-
Zhao Y, Kumbrink J, Lin BT, Bouton AH, Yang S, Toselli PA, Kirsch KH. Expression of a phosphorylated substrate domain of p130Cas promotes PyMT-induced c-Src-dependent murine breast cancer progression. Carcinogenesis. 2013 Dec; 34(12):2880-90.View Related Profiles. PMID: 23825155; PMCID: PMC3845889; DOI: 10.1093/carcin/bgt238;
-
Drew DA, Devers T, Horelik N, Yang S, O'Brien M, Wu R, Rosenberg DW. Nanoproteomic analysis of extracellular receptor kinase-1/2 post-translational activation in microdissected human hyperplastic colon lesions. Proteomics. 2013 May; 13(9):1428-36.View Related Profiles. PMID: 23467982; PMCID: PMC3805251; DOI: 10.1002/pmic.201200430;
-
Feller JK, Yang S, Mahalingam M. Immunohistochemistry with a mutation-specific monoclonal antibody as a screening tool for the BRAFV600E mutational status in primary cutaneous malignant melanoma. Mod Pathol. 2013 Mar; 26(3):414-20.View Related Profiles. PMID: 23041829; DOI: 10.1038/modpathol.2012.168;
-
-
-
Park E, Yang S, Emley A, DeCarlo K, Richards J, Mahalingam M. Lack of correlation between immunohistochemical expression of CKIT and KIT mutations in atypical acral nevi. Am J Dermatopathol. 2012 Feb; 34(1):41-6.View Related Profiles. PMID: 22094233; DOI: 10.1097/DAD.0b013e31821ec0ef;
-
Miller DD, Emley A, Yang S, Richards JE, Lee JE, Deng A, Hoang MP, Mahalingam M. Mixed versus pure variants of desmoplastic melanoma: a genetic and immunohistochemical appraisal. Mod Pathol. 2012 Apr; 25(4):505-15.View Related Profiles. PMID: 22157936; DOI: 10.1038/modpathol.2011.196;
-
-
-
Hetzel JT, Huang CS, Coukos JA, Omstead K, Cerda SR, Yang S, O'Brien MJ, Farraye FA. Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol. 2010 Dec; 105(12):2656-64.View Related Profiles. PMID: 20717107; DOI: 10.1038/ajg.2010.315;
-
Decarlo K, Yang S, Emley A, Wajapeyee N, Green M, Mahalingam M. Oncogenic BRAF-positive dysplastic nevi and the tumor suppressor IGFBP7--challenging the concept of dysplastic nevi as precursor lesions? Hum Pathol. 2010 Jun; 41(6):886-94.View Related Profiles. PMID: 20233623; DOI: 10.1016/j.humpath.2009.12.002;
-
-
Lee JC, Yang S, Zou Y, Joseph L. Erythroid/B-cell biphenotypic acute leukemia first case report. Leukemia. 2009 Oct; 23(10):1920-3. PMID: 19458630; DOI: 10.1038/leu.2009.105;
-
Kovacheva VP, Davison JM, Mellott TJ, Rogers AE, Yang S, O'Brien MJ, Blusztajn JK. Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival. FASEB J. 2009 Apr; 23(4):1054-63.View Related Profiles. PMID: 19047067; PMCID: PMC2660648; DOI: 10.1096/fj.08-122168;
-
-
Michael J O’Brien, Shi Yang, Christopher S Huang, Courtney Shepherd, Sandra Cerda, Francis A Farraye
. The Serrated Polyp Pathway to Colorectal Carcinoma. Diagnostic Histopathology
. 2008; 14(2):78-93.
-
Belguise K, Guo S, Yang S, Rogers AE, Seldin DC, Sherr DH, Sonenshein GE. Green tea polyphenols reverse cooperation between c-Rel and CK2 that induces the aryl hydrocarbon receptor, slug, and an invasive phenotype. Cancer Res. 2007 Dec 15; 67(24):11742-50.View Related Profiles. PMID: 18089804
-
Rosenberg DW, Yang S, Pleau DC, Greenspan EJ, Stevens RG, Rajan TV, Heinen CD, Levine J, Zhou Y, O'Brien MJ. Mutations in BRAF and KRAS differentially distinguish serrated versus non-serrated hyperplastic aberrant crypt foci in humans. Cancer Res. 2007 Apr 15; 67(8):3551-4.View Related Profiles. PMID: 17440063
-
O'Brien MJ, Yang S, Mack C, Xu H, Huang CS, Mulcahy E, Amorosino M, Farraye FA. Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points. Am J Surg Pathol. 2006 Dec; 30(12):1491-501.View Related Profiles. PMID: 17122504
-
Sharov AA, Sharova TY, Mardaryev AN, Tommasi di Vignano A, Atoyan R, Weiner L, Yang S, Brissette JL, Dotto GP, Botchkarev VA. Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes. Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48):18166-71.View Related Profiles. PMID: 17114283; PMCID: PMC1838724; DOI: 10.1073/pnas.0608899103;
-
Murray SA, Yang S, Demicco E, Ying H, Sherr DH, Hafer LJ, Rogers AE, Sonenshein GE, Xiao ZX. Increased expression of MDM2, cyclin D1, and p27Kip1 in carcinogen-induced rat mammary tumors. J Cell Biochem. 2005 Aug 1; 95(5):875-84.View Related Profiles. PMID: 15844214
-
Huang CS, O'brien MJ, Yang S, Farraye FA. Hyperplastic polyps, serrated adenomas, and the serrated polyp neoplasia pathway. Am J Gastroenterol. 2004 Nov; 99(11):2242-55.View Related Profiles. PMID: 15555008
-
Yang S, Farraye FA, Mack C, Posnik O, O'Brien MJ. BRAF and KRAS Mutations in hyperplastic polyps and serrated adenomas of the colorectum: relationship to histology and CpG island methylation status. Am J Surg Pathol. 2004 Nov; 28(11):1452-9.View Related Profiles. PMID: 15489648
-
O'Brien MJ, Yang S, Clebanoff JL, Mulcahy E, Farraye FA, Amorosino M, Swan N. Hyperplastic (serrated) polyps of the colorectum: relationship of CpG island methylator phenotype and K-ras mutation to location and histologic subtype. Am J Surg Pathol. 2004 Apr; 28(4):423-34.View Related Profiles. PMID: 15087661
-
Trombino AF, Near RI, Matulka RA, Yang S, Hafer LJ, Toselli PA, Kim DW, Rogers AE, Sonenshein GE, Sherr DH. Expression of the aryl hydrocarbon receptor/transcription factor (AhR) and AhR-regulated CYP1 gene transcripts in a rat model of mammary tumorigenesis. Breast Cancer Res Treat. 2000 Sep; 63(2):117-31.View Related Profiles. PMID: 11097088
-
Robles R, Morita Y, Mann KK, Perez GI, Yang S, Matikainen T, Sherr DH, Tilly JL. The aryl hydrocarbon receptor, a basic helix-loop-helix transcription factor of the PAS gene family, is required for normal ovarian germ cell dynamics in the mouse. Endocrinology. 2000 Jan; 141(1):450-3.View Related Profiles. PMID: 10614669
-
Mulligan NJ, Yang S, Andry C, Klein M, O'Brien MJ. The role of p21ras in pancreatic neoplasia and chronic pancreatitis. Hum Pathol. 1999 Jun; 30(6):602-10.View Related Profiles. PMID: 10374765
-
Rogers AE, Hafer LJ, Iskander YS, Yang S. Black tea and mammary gland carcinogenesis by 7,12-dimethylbenz[a]anthracene in rats fed control or high fat diets. Carcinogenesis. 1998 Jul; 19(7):1269-73.View Related Profiles. PMID: 9683188
-
Yamaguchi K, Matulka RA, Shneider AM, Toselli P, Trombino AF, Yang S, Hafer LJ, Mann KK, Tao XJ, Tilly JL, Near RI, Sherr DH. Induction of PreB cell apoptosis by 7,12-dimethylbenz[a]anthracene in long-term primary murine bone marrow cultures. Toxicol Appl Pharmacol. 1997 Dec; 147(2):190-203.View Related Profiles. PMID: 9439715
-
Schroy PC, Brown-Shimer S, Kim K, Johnson KA, Murnane MJ, Yang S, O'Brien MJ, Carney WP, Kupchik HZ. Detection of p21ras mutations in colorectal adenomas and carcinomas by enzyme-linked immunosorbent assay. Cancer. 1995 Jul 15; 76(2):201-9.View Related Profiles. PMID: 8625092
-
Kelly CP, O'Keane JC, Orellana J, Schroy PC, Yang S, LaMont JT, Brady HR. Human colon cancer cells express ICAM-1 in vivo and support LFA-1-dependent lymphocyte adhesion in vitro. Am J Physiol. 1992 Dec; 263(6 Pt 1):G864-70.View Related Profiles. PMID: 1362041
-
Yang S. [Papilloma of forestomach induced by Fusarium T-2 toxin in mice]. Zhonghua Zhong Liu Za Zhi. 1988 Sep; 10(5):339-41. PMID: 3248499
-
Yang S, Xia QJ. [Studies on the promoting and initiating effects of Fusarium T-2 toxin]. Zhonghua Bing Li Xue Za Zhi. 1988 Jun; 17(2):107-10. PMID: 3145156
This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
| Year | Publications |
|---|
| 1988 | 2 |
| 1992 | 1 |
| 1995 | 1 |
| 1997 | 1 |
| 1998 | 1 |
| 1999 | 1 |
| 2000 | 2 |
| 2004 | 3 |
| 2005 | 1 |
| 2006 | 2 |
| 2007 | 2 |
| 2008 | 3 |
| 2009 | 2 |
| 2010 | 4 |
| 2011 | 1 |
| 2012 | 4 |
| 2013 | 3 |
| 2014 | 6 |
| 2015 | 3 |
| 2016 | 4 |
| 2017 | 2 |
| 2018 | 3 |