Vladimir A Botchkarev, MD, PhD
Adjunct Professor
Boston University School of Medicine
Dept of Dermatology
Dermatology (excluding Mohs Surgery)

MD, Chuvash State University
PhD, Peoples' Friendship University of Russia



Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Adjunct Professor
Boston University School of Medicine
Pathology & Laboratory Medicine




Epigenetic regulation of skin development and keratinocyte differentiation
09/01/2014 - 08/31/2018 (PI)
NIH/National Institute of Arthritis & Mu
5R01AR064580-03

Chromatin architectural protein CTCF and regulation of skin development and tumorigenesis
02/15/2017 - 12/31/2017 (PI)
NIH/National Institute of Arthritis & Mu
1R01AR071727-01

BMP Signaling in the Control of Skin Development, Hair Growth and Tumorogenesis
07/01/2010 - 06/30/2016 (PI)
NIH/National Institute of Arthritis & Mu
5R01AR049778-11

Modulation of Chemotherapy-Induced Hair Loss
06/01/2012 - 04/30/2013 (PI)
Edimer Pharmaceuticals, Inc


Role Smad 1/5 Proteins on Hair Follicle Development and Cycling
03/01/2006 - 02/28/2008 (Co-PI)
North American Hair Research Society

An Ex Vivo Human Model for Chemotherapy-Induced Hair Loss: The Effect of E2/Drbeta in Prevention Doxorubicin-Induced Hair Loss
08/15/2006 - 07/31/2007 (PI)
Berlex

A Research Study to Evaluate the Effects of Various Topical Compounds on Hair Growth and Hair and Skin Pigmentation as Tested in Mice
03/01/2005 - 05/31/2007 (PI)
Duke University

Molecular Mechanisms of Chemotherapy-Induced Hair Loss
06/16/2003 - 05/31/2007 (PI)
NIH/National Cancer Institute
5 R01 CA92090 03

Function of Noggin in Hair Follicle Growth and Disease
06/01/2002 - 05/31/2007 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5 K02 AR48573 05

Mentorship to Study Role of Edar Signaling in Hair Follicle Regression with Vladimir Botchkarev
02/15/2006 - 12/31/2006 (Co-PI)
North American Hair Research Society

Showing 10 of 17 results. Show All Results



Yr Title Project-Sub Proj Pubs
2017 Chromatin architectural protein CTCF and regulation of skin development and tumorigenesis 1R01AR071727-01
2017 Epigenetic regulation of skin development and keratinocyte differentiation 5R01AR064580-04 1
2016 Epigenetic regulation of skin development and keratinocyte differentiation 5R01AR064580-03 1
2015 Epigenetic regulation of skin development and keratinocyte differentiation 5R01AR064580-02 1
2014 Epigenetic regulation of skin development and keratinocyte differentiation 1R01AR064580-01A1 1
2014 Bone Morphogentic Protein signaling in the control of skin development, hair grow 5R01AR049778-11 11
2013 Bone Morphogentic Protein signaling in the control of skin development, hair grow 5R01AR049778-10 11
2012 Bone Morphogentic Protein signaling in the control of skin development, hair grow 5R01AR049778-09 11
2011 Bone Morphogentic Protein signaling in the control of skin development, hair grow 5R01AR049778-08 11
2010 Bone Morphogentic Protein signaling in the control of skin development, hair grow 2R01AR049778-07 11
Showing 10 of 27 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Poterlowicz K, Yarker JL, Malashchuk I, Lajoie BR, Mardaryev AN, Gdula MR, Sharov AA, Kohwi-Shigematsu T, Botchkarev VA, Fessing MY. 5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells. PLoS Genet. 2017 Sep; 13(9):e1006966.View Related Profiles. PMID: 28863138.
  2. Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A. p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct; 137(10):2157-2167. PMID: 28595999.
  3. Botchkarev VA. The Molecular Revolution in Cutaneous Biology: Chromosomal Territories, Higher-Order Chromatin Remodeling, and the Control of Gene Expression in Keratinocytes. J Invest Dermatol. 2017 May; 137(5):e93-e99. PMID: 28411854; DOI: 10.1016/j.jid.2016.04.040;.
  4. Botchkarev VA, Mardaryev AN. Repressing the Keratinocyte Genome: How the Polycomb Complex Subunits Operate in Concert to Control Skin and Hair Follicle Development. J Invest Dermatol. 2016 08; 136(8):1538-40. PMID: 27450498; DOI: 10.1016/j.jid.2016.04.026;.
  5. Botchkarev VA, Sharov AA. Modeling Chemotherapy-Induced Hair Loss: From Experimental Propositions toward Clinical Reality. J Invest Dermatol. 2016 Mar; 136(3):557-9. PMID: 26902124; DOI: 10.1016/j.jid.2015.10.068;.
  6. Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA. Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4; 212(1):77-89. PMID: 26711500; PMCID: PMC4700479; DOI: 10.1083/jcb.201506065;.
  7. Botchkarev VA. Integration of the Transcription Factor-Regulated and Epigenetic Mechanisms in the Control of Keratinocyte Differentiation. J Investig Dermatol Symp Proc. 2015 Nov; 17(2):30-2. PMID: 26551942; DOI: 10.1038/jidsymp.2015.37;.
  8. Botchkarev VA. Epigenetic Regulation of Epidermal Development and Keratinocyte Differentiation. J Investig Dermatol Symp Proc. 2015 Jul; 17(1):18-9. PMID: 26067308; DOI: 10.1038/jidsymp.2015.15;.
  9. Botchkarev VA, Flores ER. p53/p63/p73 in the epidermis in health and disease. Cold Spring Harb Perspect Med. 2014 Aug; 4(8). PMID: 25085956; DOI: 10.1101/cshperspect.a015248;.
  10. Sharova TY, Poterlowicz K, Botchkareva NV, Kondratiev NA, Aziz A, Spiegel JH, Botchkarev VA, Sharov AA. Complex changes in the apoptotic and cell differentiation programs during initiation of the hair follicle response to chemotherapy. J Invest Dermatol. 2014 Dec; 134(12):2873-82.View Related Profiles. PMID: 24999588; PMCID: PMC4227948; DOI: 10.1038/jid.2014.267;.
Showing 10 of 98 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 98 publications over 21 distinct years, with a maximum of 15 publications in 1999

YearPublications
19952
19974
199810
199915
20007
20014
20023
200313
20046
20054
20063
20072
20092
20103
20112
20122
20134
20144
20153
20162
20173
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609 Albany St (J Bldg)
Boston MA 02118
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