Vladimir A Botchkarev, MD, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Dermatology
Dermatology (excluding Mohs Surgery)

MD, Chuvash State University
PhD, Peoples' Friendship University of Russia



Vladimir Botchkarev, MD, PhD is Research Associate Professor in the Department of Dermatology. He received his medical training at Chuvash State University in Cheboksary, Russian and his doctoral training at People’s Friendship University in Moscow, Russia. He was a recipient of the Research Career Development Award from the Dermatology Foundation and Independent Scientist Award from the National Institutes of Health. He is also a recipient of the research grants from the NIAMS and NCI. His name was included in the books 2000 Outstanding Scientists of the 21st Century, Great Minds of the 21st Century and Who is Who in Medicine. His primary research interests are the molecular mechanisms of hair growth and pathobiology of different forms of hair loss.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences


Adjunct Professor
Boston University Chobanian & Avedisian School of Medicine
Pathology & Laboratory Medicine




Targeting Senescence to Improve Wound Healing in Aging
09/01/2023 - 05/31/2028 (Key Person / Mentor)
PI: Daniel S. Roh, MD, PhD
NIH/National Institute on Aging
1K76AG083300-01

Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation
03/16/2021 - 01/31/2026 (Multi-PI)
PI: Vladimir A Botchkarev, MD, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
3R01AR078306-04S1

The skin of naked mole rats as a model for scar-free wound healing
09/01/2023 - 08/31/2024 (Multi-PI)
PI: Vladimir A Botchkarev, MD, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
4R33AR078093-03

Mechanisms of skin cancer resistance in Naked mole-rats
07/01/2023 - 06/30/2024 (Key Person / Mentor)
Dermatology Foundation


DNA hydroxymethylation and Tet-enzymes in the control of the skin development and hair growth
08/01/2019 - 06/30/2024 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR075776-05

The skin of naked mole rats as a model for scar-free wound healing
09/01/2020 - 08/31/2023 (Multi-PI)
PI: Vladimir A Botchkarev, MD, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R61AR078093-02

Chromatin architectural protein CTCF and regulation of skin development and tumorigenesis
02/15/2017 - 04/30/2023 (Multi-PI)
PI: Vladimir A Botchkarev, MD, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR071727-05

Epigenetic regulation of skin development and keratinocyte differentiation
09/01/2014 - 08/31/2020 (Multi-PI)
PI: Vladimir A Botchkarev, MD, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR064580-05

BMP Signaling in the Control of Skin Development, Hair Growth and Tumorogenesis
07/01/2010 - 06/30/2016 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR049778-11

Modulation of Chemotherapy-Induced Hair Loss
06/01/2012 - 04/30/2013 (PI)
Edimer Pharmaceuticals, Inc


Showing 10 of 23 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2024 Genome transposable elements as drivers of inflammation in understudied skin types 3R01AR078306-04S1
2024 Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation 5R01AR078306-04
2023 Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation 5R01AR078306-03
2023 The skin of naked mole rats as a model for scar-free wound healing 4R33AR078093-03
2023 DNA hydroxymethylation and Tet-enzymes in the control of the skin development and hair growth 5R01AR075776-05
2022 Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation 5R01AR078306-02
2022 DNA hydroxymethylation and Tet-enzymes in the control of the skin development and hair growth 5R01AR075776-04
2021 Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation 1R01AR078306-01
2021 The skin of naked mole rats as a model for scar-free wound healing 5R61AR078093-02
2021 DNA hydroxymethylation and Tet-enzymes in the control of the skin development and hair growth 5R01AR075776-03
Showing 10 of 45 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Botchkarev VA, Fessing MY, Sharov AA. Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation. J Invest Dermatol. 2023 Jul; 143(7):1117-1120. PMID: 37045617; PMCID: PMC10715816; DOI: 10.1016/j.jid.2023.02.013;
     
  2. Chen GD, Fatima I, Xu Q, Rozhkova E, Fessing MY, Mardaryev AN, Sharov AA, Xu GL, Botchkarev VA. DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation. Sci Adv. 2023 Jan 13; 9(2):eabo7605.View Related Profiles. PMID: 36630508; PMCID: PMC9833667; DOI: 10.1126/sciadv.abo7605;
     
  3. Fatima I, Chen G, Botchkareva NV, Sharov AA, Thornton D, Wilkinson HN, Hardman MJ, Grutzkau A, Pedro de Magalhaes J, Seluanov A, Smith ESJ, Gorbunova V, Mardaryev AN, Faulkes CG, Botchkarev VA. Skin Aging in Long-Lived Naked Mole-Rats Is Accompanied by Increased Expression of Longevity-Associated and Tumor Suppressor Genes. J Invest Dermatol. 2022 Nov; 142(11):2853-2863.e4.View Related Profiles. PMID: 35691364; PMCID: PMC9613526; DOI: 10.1016/j.jid.2022.04.028;
     
  4. Crouch J, Shvedova M, Thanapaul RJRS, Botchkarev V, Roh D. Epigenetic Regulation of Cellular Senescence. Cells. 2022 02 15; 11(4).View Related Profiles. PMID: 35203320; PMCID: PMC8870565; DOI: 10.3390/cells11040672;
     
  5. Botchkarev VA, Sharov AA. Histone Deacetylases in the Control of Epidermal Homeostasis: From Chromatin Biology toward Therapy. J Invest Dermatol. 2022 01; 142(1):12-14. PMID: 34565558; PMCID: PMC8734647; DOI: 10.1016/j.jid.2021.06.021;
     
  6. Ahmed MI, Pickup ME, Rimmer AG, Alam M, Mardaryev AN, Poterlowicz K, Botchkareva NV, Botchkarev VA. Interplay of MicroRNA-21 and SATB1 in Epidermal Keratinocytes during Skin Aging. J Invest Dermatol. 2019 12; 139(12):2538-2542.e2. PMID: 31255698; PMCID: PMC7754164; DOI: 10.1016/j.jid.2019.04.022;
     
  7. Castellano-Pellicena I, Uzunbajakava NE, Mignon C, Raafs B, Botchkarev VA, Thornton MJ. Does blue light restore human epidermal barrier function via activation of Opsin during cutaneous wound healing? Lasers Surg Med. 2019 04; 51(4):370-382. PMID: 30168605
     
  8. Poterlowicz K, Yarker JL, Malashchuk I, Lajoie BR, Mardaryev AN, Gdula MR, Sharov AA, Kohwi-Shigematsu T, Botchkarev VA, Fessing MY. 5C analysis of the Epidermal Differentiation Complex locus reveals distinct chromatin interaction networks between gene-rich and gene-poor TADs in skin epithelial cells. PLoS Genet. 2017 Sep; 13(9):e1006966.View Related Profiles. PMID: 28863138; PMCID: PMC5599062; DOI: 10.1371/journal.pgen.1006966;
     
  9. Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A. p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct; 137(10):2157-2167. PMID: 28595999; PMCID: PMC5610935; DOI: 10.1016/j.jid.2017.05.013;
     
  10. Botchkarev VA. Second International Symposium-Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases. J Invest Dermatol. 2017 08; 137(8):1604-1608. PMID: 28583676
     
Showing 10 of 107 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 107 publications over 26 distinct years, with a maximum of 15 publications in 1999

YearPublications
19952
19974
199810
199915
20007
20014
20023
200313
20046
20054
20063
20072
20092
20103
20112
20122
20134
20145
20153
20162
20174
20181
20191
20211
20222
20232
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609 Albany St (J Bldg)
Boston MA 02118
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