Andrei A. Sharov, MD, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Dermatology
Dermatology (excluding Mohs Surgery)

MD, Chuvash State University
PhD, Chuvash State University



Andrey Sharov, MD, PhD is an Assistant Professor of Dermatology at the Chobanian and Avedisian School of Medicine. He received his postdoctoral training her after completing his graduate degrees in Russia. Dr. Sharov is studying molecular mechanisms of skin development, with particular emphasis on the regulation and maintenance of adult stem cells in the skin. His research focuses on dissecting the signal transduction pathways which regulate stem cell quiescence to better understand how alterations in these signaling pathways contribute to melanoma and non-melanoma skin cancers. In addition, Dr. Sharov studies a role of higher-order chromatin organization in the process of pigmentation funded by NIH/NIAMS.

Member
Boston University
Genome Science Institute




Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation
03/16/2021 - 01/31/2026 (Multi-PI)
PI: Andrei A. Sharov, MD, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR078306-03

The skin of naked mole rats as a model for scar-free wound healing
09/01/2020 - 08/31/2023 (Multi-PI)
PI: Andrei A. Sharov, MD, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R61AR078093-02

Chromatin architectural protein CTCF and regulation of skin development and tumorigenesis
02/15/2017 - 04/30/2023 (Multi-PI)
PI: Andrei A. Sharov, MD, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR071727-05

Epigenetic regulation of skin development and keratinocyte differentiation
09/01/2014 - 08/31/2020 (Multi-PI)
PI: Andrei A. Sharov, MD, PhD
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR064580-05

Higher-order Chromatin Remodeling and Regulation of Pigmentation
09/16/2013 - 08/31/2016 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R21AR063851-02

Modulation of pigmentation by PKC pathway inhibitors
12/05/2014 - 12/31/2015 (PI)
ChromaDerm, Inc


Molecular Control of Normal and Neoplastic Skin Stem Cells
07/01/2009 - 06/30/2014 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5K01AR056771-05

Role of BMP Pathway in Skin Stem Cell Quiescence
01/01/2007 - 06/30/2009 (PI)
American Skin Association

Role Smad 1/5 Proteins on Hair Follicle Development and Cycling
03/01/2006 - 02/28/2008 (PI)
North American Hair Research Society

Role of BMP in Hair Follicle Regression (Catagen)
03/01/2005 - 12/31/2006 (PI)
North American Hair Research Society



Title


Yr Title Project-Sub Proj Pubs
2024 Genome transposable elements as drivers of inflammation in understudied skin types 3R01AR078306-04S1
2024 Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation 5R01AR078306-04
2023 Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation 5R01AR078306-03
2023 The skin of naked mole rats as a model for scar-free wound healing 4R33AR078093-03
2022 Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation 5R01AR078306-02
2021 Transposable elements in the keratinocyte genome and their regulation during skin development and epidermal differentiation 1R01AR078306-01
2021 The skin of naked mole rats as a model for scar-free wound healing 5R61AR078093-02
2021 Chromatin architectural protein CTCF and regulation of skin development and tumorigenesis 5R01AR071727-05 2
2020 The skin of naked mole rats as a model for scar-free wound healing 1R61AR078093-01
2020 Chromatin architectural protein CTCF and regulation of skin development and tumorigenesis 5R01AR071727-04 2
Showing 10 of 25 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Botchkarev VA, Gdula MR, Mardaryev AN, Sharov AA, Fessing MY. Epigenetic regulation of gene expression in keratinocytes. J Invest Dermatol. 2012 Nov; 132(11):2505-21.View Related Profiles. PMID: 22763788; PMCID: PMC3650472; DOI: 10.1038/jid.2012.182;
     
  2. Botchkarev VA, Sharov AA. BMP signaling in the control of skin development and hair follicle growth. Differentiation. 2004 Dec; 72(9-10):512-26.View Related Profiles. PMID: 15617562
     
  3. Sharov AA, Siebenhaar F, Sharova TY, Botchkareva NV, Gilchrest BA, Botchkarev VA. Fas signaling is involved in the control of hair follicle response to chemotherapy. Cancer Res. 2004 Sep 1; 64(17):6266-70.View Related Profiles. PMID: 15342414
     
  4. Sharov AA, Weiner L, Sharova TY, Siebenhaar F, Atoyan R, Reginato AM, McNamara CA, Funa K, Gilchrest BA, Brissette JL, Botchkarev VA. Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation. EMBO J. 2003 Jun 16; 22(12):2992-3003.View Related Profiles. PMID: 12805214; PMCID: PMC162143
     
  5. Sharov AA, Li GZ, Palkina TN, Sharova TY, Gilchrest BA, Botchkarev VA. Fas and c-kit are involved in the control of hair follicle melanocyte apoptosis and migration in chemotherapy-induced hair loss. J Invest Dermatol. 2003 Jan; 120(1):27-35.View Related Profiles. PMID: 12535195
     
  6. Botchkarev VA, Botchkareva NV, Sharov AA, Funa K, Huber O, Gilchrest BA. Modulation of BMP signaling by noggin is required for induction of the secondary (nontylotrich) hair follicles. J Invest Dermatol. 2002 Jan; 118(1):3-10.View Related Profiles. PMID: 11851869
     

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 6 publications over 4 distinct years, with a maximum of 2 publications in 2003 and 2004

YearPublications
20021
20032
20042
20121


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