Jessica L. Fry Ph.D.
Assistant Professor
Curry College

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Dr. Jessica Fry is an Assistant Professor of Biology at Curry College. Dr. Fry completed her postdoctoral training at the Chobanian and Avedisian School of Medicine, studying the role of the enzyme Sirtuin-1 in the pathogenesis of arterial stiffness, hypertension, and related cardiovascular disease. She is broadly trained in physiology and molecular and cellular biology, with an S.B. in Biology from MIT and a PhD in Experimental Pathology through the Harvard Medical School Biological and Biomedical Sciences Program. Her graduate work focused on the effects of matrix remodeling protein ADAM-9 isoforms on breast cancer cell migration. Dr. Fry's teaching experience includes Introduction to Biomedical Laboratory and Clinical Sciences, Introduction to Cell Culture Techniques, Essentials of Laboratory Math, and Immunology, taught through the City Lab Academy and BLCS programs at BU Metropolitan College. She is also a certified dog trainer and the President of the New England Dog Training Club, based in Cambridge.

Postdoctoral Fellow (previously held)
Boston University Chobanian & Avedisian School of Medicine
Vascular Biology

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Petzold AM, Fry JL. Doubling down on best practices: reflecting on teaching physiology during the COVID-19 pandemic. Adv Physiol Educ. 2023 Jun 01; 47(2):352-360. PMID: 37078526; PMCID: PMC10190836; DOI: 10.1152/advan.00015.2023;
  2. Shao D, Yao C, Kim MH, Fry J, Cohen RA, Costello CE, Matsui R, Seta F, McComb ME, Bachschmid MM. Improved mass spectrometry-based activity assay reveals oxidative and metabolic stress as sirtuin-1 regulators. Redox Biol. 2019 04; 22:101150.View Related Profiles. PMID: 30877853; PMCID: PMC6423473; DOI: 10.1016/j.redox.2019.101150;
  3. Shao D, Han J, Hou X, Fry J, Behring JB, Seta F, Long MT, Roy HK, Cohen RA, Matsui R, Bachschmid MM. Glutaredoxin-1 Deficiency Causes Fatty Liver and Dyslipidemia by Inhibiting Sirtuin-1. Antioxid Redox Signal. 2017 Aug 20; 27(6):313-327.View Related Profiles. PMID: 27958883; PMCID: PMC5563925; DOI: 10.1089/ars.2016.6716;
  4. Fry JL, Al Sayah L, Weisbrod RM, Van Roy I, Weng X, Cohen RA, Bachschmid MM, Seta F. Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness. Hypertension. 2016 Sep; 68(3):775-84.View Related Profiles. PMID: 27432859; PMCID: PMC4982825; DOI: 10.1161/HYPERTENSIONAHA.116.07622;
  5. Luo T, Nocon A, Fry J, Sherban A, Rui X, Jiang B, Xu XJ, Han J, Yan Y, Yang Q, Li Q, Zang M. AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity. Diabetes. 2016 Aug; 65(8):2295-310.View Related Profiles. PMID: 27207538; PMCID: PMC4955985; DOI: 10.2337/db15-1122;
  6. Fry JL, Shiraishi Y, Turcotte R, Yu X, Gao YZ, Akiki R, Bachschmid M, Zhang Y, Morgan KG, Cohen RA, Seta F. Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension. J Am Heart Assoc. 2015 Sep; 4(9):e002384.View Related Profiles. PMID: 26376991; PMCID: PMC4599512; DOI: 10.1161/JAHA.115.002384;
  7. Shao D, Fry JL, Han J, Hou X, Pimentel DR, Matsui R, Cohen RA, Bachschmid MM. A redox-resistant sirtuin-1 mutant protects against hepatic metabolic and oxidant stress. J Biol Chem. 2014 Mar 14; 289(11):7293-306.View Related Profiles. PMID: 24451382; PMCID: PMC3953247; DOI: 10.1074/jbc.M113.520403;
  8. Weisbrod RM, Shiang T, Al Sayah L, Fry JL, Bajpai S, Reinhart-King CA, Lob HE, Santhanam L, Mitchell G, Cohen RA, Seta F. Arterial stiffening precedes systolic hypertension in diet-induced obesity. Hypertension. 2013 Dec; 62(6):1105-10.View Related Profiles. PMID: 24060894; PMCID: PMC3951434; DOI: 10.1161/HYPERTENSIONAHA.113.01744;
  9. Fry JL, Toker A. Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration. Cancer Res. 2010 Oct 15; 70(20):8187-98. PMID: 20736367; PMCID: PMC2955804; DOI: 10.1158/0008-5472.CAN-09-4231;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 9 publications over 8 distinct years, with a maximum of 2 publications in 2016


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