Erika J. Wolf, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Dept of Psychiatry

PhD, Boston University
MA, Boston University



My reseach focuses on the use of multivariate data analytic techniques, such as confirmatory factor analysis, structural equation modeling, latent class analysis, and item response theory, to evaluate trauma, posttraumatic stress disorder (PTSD), and related comorbidity. I am currently studying the genetics of latent psychopathology using both twin and molecular genetic methodologies. In particular, my recent work has focused on the idea that PTSD is associated with accelerated cellular aging, as reflected in DNA methylation and as manifested in physical health and neurocognitive decline.

VA Boston Healthcare System




Longitudinal Neurometabolic Outcomes of Traumatic Stress-Related Accelerated Cellular Aging
09/15/2020 - 08/30/2024 (PI)
NIH/National Institute on Aging
1RF1AG068121-01

Neurobiological Correlates of Accelerated Cellular Aging
02/15/2019 - 01/31/2022 (PI)
NIH/National Institute on Aging
5R21AG061367-02

Traumatic Stress and Accelerated Aging in DNA Methylation
04/15/2016 - 03/31/2019 (PI)
NIH/National Institute on Aging
3R03AG051877-02S1



Title
PTSD-Related Accelerated Aging in DNA Methylation and Risk for Metabolic Syndrome
(PI)

Neurobiological Correlates of Accelerated Cellular Aging
(PI)

Traumatic Stress and Accelerated Aging in DNA Methylation
(PI)



Yr Title Project-Sub Proj Pubs
2021 PTSD-Related Accelerated Aging in DNA Methylation and Risk for Metabolic Syndrome 5I01CX001276-05 11
2020 Longitudinal Neurometabolic Outcomes of Traumatic Stress-Related Accelerated Cellular Aging 1RF1AG068121-01
2020 Neurobiological Correlates of Accelerated Cellular Aging 5R21AG061367-02
2019 Neurobiological Correlates of Accelerated Cellular Aging 1R21AG061367-01
2019 PTSD-Related Accelerated Aging in DNA Methylation and Risk for Metabolic Syndrome 5I01CX001276-04 11
2018 PTSD-Related Accelerated Aging in DNA Methylation and Risk for Metabolic Syndrome 5I01CX001276-03 11
2017 PTSD-Related Accelerated Aging in DNA Methylation and Risk for Metabolic Syndrome 5I01CX001276-02 11
2017 Traumatic Stress and Accelerated Aging in DNA Methylation 5R03AG051877-02 14
2017 Traumatic Stress and Accelerated Aging in DNA Methylation 3R03AG051877-02S1 14
2016 PTSD-Related Accelerated Aging in DNA Methylation and Risk for Metabolic Syndrome 1I01CX001276-01A2 11
Showing 10 of 14 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Hawn SE, Wolf EJ, Neale Z, Miller MW. Conceptualizing traumatic stress and the structure of posttraumatic psychopathology through the lenses of RDoC and HiTOP. Clin Psychol Rev. 2022 Jul; 95:102177.View Related Profiles. PMID: 35690042; PMCID: PMC9229497; DOI: 10.1016/j.cpr.2022.102177;
     
  2. Hawn SE, Neale Z, Wolf EJ, Zhao X, Pierce M, Fein-Schaffer D, Milberg W, McGlinchey R, Logue M, Miller MW. Methylation of the AIM2 gene: An epigenetic mediator of PTSD-related inflammation and neuropathology plasma biomarkers. Depress Anxiety. 2022 Apr; 39(4):323-333.View Related Profiles. PMID: 35312143; PMCID: PMC8996332; DOI: 10.1002/da.23247;
     
  3. Zheng Y, Garrett ME, Sun D, Clarke-Rubright EK, Haswell CC, Maihofer AX, Elman JA, Franz CE, Lyons MJ, Kremen WS, Peverill M, Sambrook K, McLaughlin KA, Davenport ND, Disner S, Sponheim SR, Andrew E, Korgaonkar M, Bryant R, Varkevisser T, Geuze E, Coleman J, Beckham JC, Kimbrel NA, Sullivan D, Miller M, Hayes J, Verfaellie M, Wolf E, Salat D, Spielberg JM, Milberg W, McGlinchey R, Dennis EL, Thompson PM, Medland S, Jahanshad N, Nievergelt CM, Ashley-Koch AE, Logue MW, Morey RA. Trauma and posttraumatic stress disorder modulate polygenic predictors of hippocampal and amygdala volume. Transl Psychiatry. 2021 12 16; 11(1):637.View Related Profiles. PMID: 34916497; PMCID: PMC8677780; DOI: 10.1038/s41398-021-01707-x;
     
  4. Fein-Schaffer D, Hawn SE, Annunziata AJ, Ryabchenko K, Miller MW, Wolf EJ. Premorbid traumatic stress and veteran responses to the COVID-19 pandemic. J Trauma Stress. 2022 Apr; 35(2):559-569.View Related Profiles. PMID: 34861065; PMCID: PMC9015518; DOI: 10.1002/jts.22770;
     
  5. Maihofer AX, Choi KW, Coleman JRI, Daskalakis NP, Denckla CA, Ketema E, Morey RA, Polimanti R, Ratanatharathorn A, Torres K, Wingo AP, Zai CC, Aiello AE, Almli LM, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegovic E, Borglum AD, Babic D, Bækvad-Hansen M, Baker DG, Beckham JC, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Bradley B, Brashear M, Breen G, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Calabrese JR, Caldas-de-Almeida JM, Chen CY, Dale AM, Dalvie S, Deckert J, Delahanty DL, Dennis MF, Disner SG, Domschke K, Duncan LE, Džubur Kulenovic A, Erbes CR, Evans A, Farrer LA, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gautam A, Gelaye B, Gelernter J, Geuze E, Gillespie CF, Goçi A, Gordon SD, Guffanti G, Hammamieh R, Hauser MA, Heath AC, Hemmings SMJ, Hougaard DM, Jakovljevic M, Jett M, Johnson EO, Jones I, Jovanovic T, Qin XJ, Karstoft KI, Kaufman ML, Kessler RC, Khan A, Kimbrel NA, King AP, Koen N, Kranzler HR, Kremen WS, Lawford BR, Lebois LAM, Lewis C, Liberzon I, Linnstaedt SD, Logue MW, Lori A, Lugonja B, Luykx JJ, Lyons MJ, Maples-Keller JL, Marmar C, Martin NG, Maurer D, Mavissakalian MR, McFarlane A, McGlinchey RE, McLaughlin KA, McLean SA, Mehta D, Mellor R, Michopoulos V, Milberg W, Miller MW, Morris CP, Mors O, Mortensen PB, Nelson EC, Nordentoft M, Norman SB, O'Donnell M, Orcutt HK, Panizzon MS, Peters ES, Peterson AL, Peverill M, Pietrzak RH, Polusny MA, Rice JP, Risbrough VB, Roberts AL, Rothbaum AO, Rothbaum BO, Roy-Byrne P, Ruggiero KJ, Rung A, Rutten BPF, Saccone NL, Sanchez SE, Schijven D, Seedat S, Seligowski AV, Seng JS, Sheerin CM, Silove D, Smith AK, Smoller JW, Sponheim SR, Stein DJ, Stevens JS, Teicher MH, Thompson WK, Trapido E, Uddin M, Ursano RJ, van den Heuvel LL, Van Hooff M, Vermetten E, Vinkers CH, Voisey J, Wang Y, Wang Z, Werge T, Williams MA, Williamson DE, Winternitz S, Wolf C, Wolf EJ, Yehuda R, Young KA, Young RM, Zhao H, Zoellner LA, Haas M, Lasseter H, Provost AC, Salem RM, Sebat J, Shaffer RA, Wu T, Ripke S, Daly MJ, Ressler KJ, Koenen KC, Stein MB, Nievergelt CM. Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. Biol Psychiatry. 2022 Apr 01; 91(7):626-636.View Related Profiles. PMID: 34865855; PMCID: PMC8917986; DOI: 10.1016/j.biopsych.2021.09.020;
     
  6. Logue MW, Zhou Z, Morrison FG, Wolf EJ, Daskalakis NP, Chatzinakos C, Georgiadis F, Labadorf AT, Girgenti MJ, Young KA, Williamson DE, Zhao X, Grenier JG, Huber BR, Miller MW. Gene expression in the dorsolateral and ventromedial prefrontal cortices implicates immune-related gene networks in PTSD. Neurobiol Stress. 2021 Nov; 15:100398.View Related Profiles. PMID: 34646915; PMCID: PMC8498459; DOI: 10.1016/j.ynstr.2021.100398;
     
  7. Wolf EJ, Zhao X, Hawn SE, Morrison FG, Zhou Z, Fein-Schaffer D, Huber B, Miller MW, Logue MW. Gene expression correlates of advanced epigenetic age and psychopathology in postmortem cortical tissue. Neurobiol Stress. 2021 Nov; 15:100371.View Related Profiles. PMID: 34458511; PMCID: PMC8377489; DOI: 10.1016/j.ynstr.2021.100371;
     
  8. Sumner JA, Maihofer AX, Michopoulos V, Rothbaum AO, Almli LM, Andreassen OA, Ashley-Koch AE, Baker DG, Beckham JC, Bradley B, Breen G, Coleman JRI, Dale AM, Dennis MF, Feeny NC, Franz CE, Garrett ME, Gillespie CF, Guffanti G, Hauser MA, Hemmings SMJ, Jovanovic T, Kimbrel NA, Kremen WS, Lawford BR, Logue MW, Lori A, Lyons MJ, Maples-Keller J, Mavissakalian MR, McGlinchey RE, Mehta D, Mellor R, Milberg W, Miller MW, Morris CP, Panizzon MS, Ressler KJ, Risbrough VB, Rothbaum BO, Roy-Byrne P, Seedat S, Smith AK, Stevens JS, van den Heuvel LL, Voisey J, Young RM, Zoellner LA, Nievergelt CM, Wolf EJ. Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis. Front Neurosci. 2021; 15:678503.View Related Profiles. PMID: 34248484; PMCID: PMC8262489; DOI: 10.3389/fnins.2021.678503;
     
  9. Escarfulleri S, Ellickson-Larew S, Fein-Schaffer D, Mitchell KS, Wolf EJ. Emotion regulation and the association between PTSD, diet, and exercise: a longitudinal evaluation among US military veterans. Eur J Psychotraumatol. 2021 Apr 13; 12(1):1895515.View Related Profiles. PMID: 33907611; PMCID: PMC8049465; DOI: 10.1080/20008198.2021.1895515;
     
  10. Katrinli S, Zheng Y, Gautam A, Hammamieh R, Yang R, Venkateswaran S, Kilaru V, Lori A, Hinrichs R, Powers A, Gillespie CF, Wingo AP, Michopoulos V, Jovanovic T, Wolf EJ, McGlinchey RE, Milberg WP, Miller MW, Kugathasan S, Jett M, Logue MW, Ressler KJ, Smith AK. PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L. Brain Behav Immun. 2021 01; 91:429-436.View Related Profiles. PMID: 33152445; PMCID: PMC7749859; DOI: 10.1016/j.bbi.2020.10.023;
     
Showing 10 of 114 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 114 publications over 18 distinct years, with a maximum of 18 publications in 2017

YearPublications
20031
20041
20051
20083
20092
20103
20113
20128
201310
20147
201511
201611
201718
201810
20198
20208
20217
20222

2016 United States Government: Presidential Early Career Award for Scientists and Engineers (PECASE)
2014 Division 56 (Trauma Psychology), American Psychological Association: Outstanding Contribution to Trauma Psychology by an Early Career Psychologist
2014 International Society for Traumatic Stress Studies: Chaim and Bela Danieli Young Professional Award
2010 Division 56 (Trauma Psychology), American Psychological Association : Outstanding Dissertation in the Field of Trauma Psychology
2009 International Society for Traumatic Stress Studies : Outstanding Student Achievement Award
2008 International Society for Traumatic Stress Studies : DSM-V Essay Award
2008 Boston University: Women’s Guild Award
2007 Boston University: Clara Mayo Award
2005 International Society for Traumatic Stress Studies : Student Research Award
2001 Harvard University Extension School: Reginald Phelps Commencement Award
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