Donald M. Lloyd-Jones, MD
Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Preventive Medicine & Epidemiology

MD, Columbia University College of Physicians and Surgeons
MS, Harvard School of Public Health



Dr. Lloyd-Jones’ research interests include the study of the mechanisms and life course of cardiovascular health and healthy aging, and cardiovascular disease epidemiology, risk estimation and prevention. Other areas of interest include the use of novel biomarkers and imaging of subclinical atherosclerosis to improve prevention, and the epidemiology and outcomes of hypertension and dyslipidemia. His clinical and teaching interests lie in general cardiology, with a focus on prevention.

He also has been a national leader in public health and clinical approaches to promoting cardiovascular health and preventing cardiovascular diseases across the life course. He served as co-chair of the Risk Assessment Guidelines and a member of the Cholesterol Treatment Guidelines Panel for the 2013 ACC/AHA Guidelines for Cardiovascular Disease Risk Reduction; and was the lead member for risk assessment on the 2018 Cholesterol Guidelines Panel and the 2019 Primary Prevention Guidelines Panel. He has authored over 750 peer-reviewed scientific publications and has been a PI or co-investigator on more than 120 grants (the vast majority from NIH)

Director of Framingham Center for Population and Prevention Science
Boston University
Framingham Heart Study


Principal Investigator of the Framingham Heart Study
Boston University
Framingham Heart Study


Chief of the section of Preventive Medicine
Boston University
Preventive Medicine




Framingham Heart Study
02/14/2025 - 02/13/2032 (Multi-PI)
PI: Donald M. Lloyd-Jones, MD
NIH/National Heart, Lung, and Blood Institute


Interpregnancy as a Critical Period for Maternal-Child Cardiovascular Health in Pediatric Clinics: Ancillary to Young Hearts
03/01/2025 - 02/28/2029 (Subcontract PI)
Ann & Robert H. Lurie Children's Hospital Of Chicago NIH NHLBI
5R01HL167876-02

Integrated epidemiology of systemic and plaque-specific immunologic features of human atherosclerosis
01/01/2025 - 05/31/2028 (Subcontract PI)
Northwestern University NIH NHLBI
1R01HL175893-01

Hyperglycemia and Adverse Pregnancy Outcome Study-Cardiovascular Health of HAPO Offspring (HAPO CVH)
03/01/2025 - 02/29/2028 (Subcontract PI)
Ann & Robert H. Lurie Children's Hospital Of Chicago NIH NHLBI
5R01HL160921-03

Genetic Architecture of Cardiac Structure and Function and Its Impact on Heart Failure
01/01/2025 - 06/30/2026 (Subcontract PI)
University of Texas Health Science Center, Houston NIH NHLBI
5R01HL160793-03

Cardiovascular-kidney-metabolic health status in young adulthood: The Future of Families and Cardiovascular Health Among Young Adults (FF-CHAYA) Study
06/20/2025 - 05/30/2026 (Key Person / Mentor)
PI: Vaishnavi Krishnan
American Heart Association


Dynamic Inflammatory Determinants of Heart Failure
01/01/2025 - 03/31/2026 (Subcontract PI)
Northwestern University American Heart Assoc


Cardiovascular Health Trajectories from Birth Thru Adolescence in A Diverse Cohort of Children
01/01/2025 - 03/31/2026 (Subcontract PI)
Northwestern University NIH NHLBI
5R01HL155864-04

Dementia Risk Prediction Pooling Project
01/01/2025 - 08/31/2025 (Subcontract PI)
Northwestern University NIH NINDS
5R33NS120245-04

The Fragile Families Cardiovascular Health Follow Up Study
01/01/2025 - 07/31/2025 (Subcontract PI)
The Trustees of Princeton University NIH NHLBI
5R01HL149869-04

Showing 10 of 11 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2025 Hyperglycemia and Adverse Pregnancy Outcome Study-Cardiovascular Health of HAPO Offspring (HAPO CVH) 5R01HL160921-03
2024 Hyperglycemia and Adverse Pregnancy Outcome Study-Cardiovascular Health of HAPO Offspring (HAPO CVH) 5R01HL160921-02
2023 Hyperglycemia and Adverse Pregnancy Outcome Study-Cardiovascular Health of HAPO Offspring (HAPO CVH) 1R01HL160921-01A1
2023 The Fragile Families Cardiovascular Health Follow Up Study 5R01HL149869-04
2022 The Fragile Families Cardiovascular Health Follow Up Study 5R01HL149869-03
2021 The Fragile Families Cardiovascular Health Follow Up Study 5R01HL149869-02
2020 The Fragile Families Cardiovascular Health Follow Up Study 1R01HL149869-01A1
2019 Northwestern University Clinical and Translational Science Institute (NUCATS) 2UL1TR001422-05A1 667
2018 Northwestern University Clinical and Translational Science Institute (NUCATS) 5UL1TR001422-04 667
2018 Northwestern University Clinical and Translational Science Institute (NUCATS) 3UL1TR001422-04S1 667
Showing 10 of 32 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Website       Copy PMIDs To Clipboard

  1. Zheutlin AR, Handoo F, Luebbe S, Ning H, Sniderman A, Stone NJ, Otvos JD, Jacobs DR, Allen N, Kohli-Lynch CN, Lloyd-Jones DM, Wilkins JT. Cumulative exposure to atherogenic lipoprotein particles in young adults and subsequent incident atherosclerotic cardiovascular disease. Eur Heart J. 2025 Nov 03; 46(41):4302-4312. PMID: 40613415
     
  2. Mathew GM, Reichenberger DA, Master L, Buxton OM, Chang AM, Schneper L, Allen NB, Goldman N, Lloyd-Jones DM, Notterman DA, Hale L. Actigraphic Sleep Health During Adolescence Predicts Young Adult Cardiovascular Health. JACC Adv. 2025 Oct 27; 4(11 Pt 1):102261. PMID: 41151392; DOI: 10.1016/j.jacadv.2025.102261;
     
  3. Lee H, Huang X, Khan SS, Son D, Lee HH, Kim EJ, Lloyd-Jones DM, Kim HC, Greenland P. Very High Prevalence of Nonoptimally Controlled Traditional Risk Factors at the Onset of Cardiovascular Disease. J Am Coll Cardiol. 2025 Oct 07; 86(14):1017-1029. PMID: 41033739; DOI: 10.1016/j.jacc.2025.07.014;
     
  4. Khan SS, Huang X, Ndumele CE, Blumenthal RS, Pencina MJ, Sniderman AD, Shah NS, Wilkins JT, Lloyd-Jones DM. Statin Eligibility According to Atherosclerotic Cardiovascular Disease Risk in the US. JAMA Cardiol. 2025 Oct 01; 10(10):1071-1073.View Related Profiles. PMID: 40833687; PMCID: PMC12368784; DOI: 10.1001/jamacardio.2025.2725;
     
  5. Guo JW, Ning H, Allen NB, Perak AM, Walker JM, Pettee Gabriel K, Lloyd-Jones DM. Cardiovascular Health Changes in Young Adults and Risk of Later-Life Cardiovascular Disease. JAMA Netw Open. 2025 Oct 01; 8(10):e2535573. PMID: 41051778; PMCID: PMC12501802; DOI: 10.1001/jamanetworkopen.2025.35573;
     
  6. Bowling CB, Sloane R, Faldowski RA, Pieper CF, Brown TH, Dooley EE, Burrows BT, Bhatt AS, Lloyd-Jones DM, Lewis CE, Pettee Gabriel K. Association of multimorbidity trajectories from early adulthood through middle age with middle-age physical function. J Gerontol A Biol Sci Med Sci. 2025 Sep 19; 80(10). PMID: 40580466; PMCID: PMC12449251; DOI: 10.1093/gerona/glaf140;
     
  7. Aggarwal B, Gao Y, Alfini A, Azarbarzin A, Anafi RC, Glazer Baron K, Bautch VL, Bowles N, Broussard JL, Brown M, Cheng P, Cook SH, Cortese R, Fernandez FX, Galis Z, Johnson DA, Jelic S, Lipton JO, Lutsey PL, Miao Q, Ordovas JM, Prather AA, Swirski FK, Tasali E, Vargas I, Grandner MA, Lloyd-Jones D. Sleep and circadian rhythms in cardiovascular resilience: mechanisms, implications, and a Roadmap for research and interventions. Nat Rev Cardiol. 2025 Sep 18. PMID: 40968347
     
  8. Wang Z, Taylor KD, Rotter JI, Rich SS, Zheng Y, Hou L, Guo X, Bressler J, Raffield LM, Liu Y, Kaplan R, Lloyd-Jones DM, Morrison AC, Fornage M, Sofer T. Estimating population structure using epigenome-wide methylation data. medRxiv. 2025 Sep 02. PMID: 40950500; PMCID: PMC12425055; DOI: 10.1101/2025.09.01.25334865;
     
  9. Krishnan V, Huang X, Perak AM, Coresh J, Ndumele CE, Greenland P, Lloyd-Jones DM, Khan SS. PREVENT Risk Age Equations and Population Distribution in US Adults. JAMA Cardiol. 2025 Sep 01; 10(9):962-964.View Related Profiles. PMID: 40737004; PMCID: PMC12311814; DOI: 10.1001/jamacardio.2025.2427;
     
  10. Cameron NA, Petito LC, Colangelo LA, Gunderson EP, Catov JM, Grobman WA, Rana JS, Terry JG, Lloyd-Jones DM, Allen NB, Khan SS. Prepregnancy Cardiovascular Health, Gestational Diabetes, and Coronary Artery Calcium. JAMA Cardiol. 2025 Sep 01; 10(9):888-895. PMID: 40560557; PMCID: PMC12199180; DOI: 10.1001/jamacardio.2025.1887;
     
Showing 10 of 811 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 811 publications over 29 distinct years, with a maximum of 84 publications in 2021

YearPublications
19961
19983
19991
20002
20011
20025
20034
200411
200515
200612
200718
200812
200919
201014
201132
201231
201330
201423
201540
201639
201743
201841
201949
202070
202184
202277
202346
202440
202548


Recent (within 3 months)

8 Ways to Stay Healthy As You Age

Time 11/6/2025
Contact for Mentoring:

72 E. Concord St
Boston MA 02118
Google Map


Lloyd-Jones's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Media Mentions
_
Co-Authors
_
Similar People
_
Same Department