Nelson Lau, PhD
Associate Professor
Boston University School of Medicine
Dept of Biochemistry

PhD, Massachusetts Institute of Technology




Director
Boston University School of Medicine
Genome Science Institute




Transposon landscapes and transcriptome diversity in aging neurons
01/01/2018 - 03/31/2021 (PI)
NIH/National Institute on Aging
3R01AG052465-04S1

THE IMPACT OF PIWI ASSOCIATED TRANSCRIPTS IN XENOPUS GERM CELL DEVELOPMENT
09/12/2017 - 05/31/2019 (PI)
NIH/National Institute of Child Health & Human Development
5R21HD088792-03




Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Zeldich E, Chen CD, Boden E, Howat B, Nasse JS, Zeldich D, Lambert AG, Yuste A, Cherry JD, Mathias RM, Ma Q, Lau NC, McKee AC, Hatzipetros T, Abraham CR. Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS. J Mol Neurosci. 2019 Jun 27.View Related Profiles. PMID: 31250273.
     
  2. Gushchanskaia ES, Esse R, Ma Q, Lau NC, Grishok A. Interplay between small RNA pathways shapes chromatin landscapes in C. elegans. Nucleic Acids Res. 2019 Jun 20; 47(11):5603-5616.View Related Profiles. PMID: 31216042.
     
  3. Kozeretska IA, Shulha VI, Serga SV, Rozhok AI, Protsenko OV, Lau NC. A rapid change in P-element-induced hybrid dysgenesis status in Ukrainian populations of Drosophila melanogaster. Biol Lett. 2018 08; 14(8). PMID: 30135116.
     
  4. Clark JP, Rahman R, Yang N, Yang LH, Lau NC. Drosophila PAF1 Modulates PIWI/piRNA Silencing Capacity. Curr Biol. 2017 Sep 11; 27(17):2718-2726.e4. PMID: 28844648.
     
  5. Toombs JA, Sytnikova YA, Chirn GW, Ang I, Lau NC, Blower MD. Xenopus Piwi proteins interact with a broad proportion of the oocyte transcriptome. RNA. 2017 Apr; 23(4):504-520. PMID: 28031481; DOI: 10.1261/rna.058859.116;.
     
  6. Madison-Villar MJ, Sun C, Lau NC, Settles ML, Mueller RL. Small RNAs from a Big Genome: The piRNA Pathway and Transposable Elements in the Salamander Species Desmognathus fuscus. J Mol Evol. 2016 Oct; 83(3-4):126-136. PMID: 27743003; DOI: 10.1007/s00239-016-9759-3;.
     
  7. Chirn GW, Rahman R, Sytnikova YA, Matts JA, Zeng M, Gerlach D, Yu M, Berger B, Naramura M, Kile BT, Lau NC. Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals. PLoS Genet. 2015 Nov; 11(11):e1005652. PMID: 26588211; PMCID: PMC4654475; DOI: 10.1371/journal.pgen.1005652;.
     
  8. Rahman R, Chirn GW, Kanodia A, Sytnikova YA, Brembs B, Bergman CM, Lau NC. Unique transposon landscapes are pervasive across Drosophila melanogaster genomes. Nucleic Acids Res. 2015 Dec 15; 43(22):10655-72. PMID: 26578579; DOI: 10.1093/nar/gkv1193;.
     
  9. Post C, Clark JP, Sytnikova YA, Chirn GW, Lau NC. The capacity of target silencing by Drosophila PIWI and piRNAs. RNA. 2014 Dec; 20(12):1977-86. PMID: 25336588; PMCID: PMC4238361; DOI: 10.1261/rna.046300.114;.
     
  10. Sytnikova YA, Rahman R, Chirn GW, Clark JP, Lau NC. Transposable element dynamics and PIWI regulation impacts lncRNA and gene expression diversity in Drosophila ovarian cell cultures. Genome Res. 2014 Dec; 24(12):1977-90. PMID: 25267525; PMCID: PMC4248314; DOI: 10.1101/gr.178129.114;.
     
Showing 10 of 37 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 37 publications over 17 distinct years, with a maximum of 7 publications in 2014

YearPublications
20011
20021
20032
20042
20054
20061
20072
20081
20093
20102
20133
20147
20152
20162
20171
20181
20192
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

PIWI Subfamily of Argonaute Proteins
Piwi-Interacting RNA
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Boston MA 02118
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