Marie-Helene Saint-Hilaire, MD
Professor
Boston University School of Medicine
Dept of Neurology

MD, Université de Montréal



Movement Disorder specialist, especially in the field of Parkinson Disease. Director of the APDA advanced center for Parkinson disease research at Boston University. Expertise in clinical care of patients with movement disorders, and in clinical research including epidemiology, rehabilitation, and surgery for Parkinson Disease.

Ad Interim Chair
Boston University School of Medicine
Neurology




APDA Information and Referral center
09/01/1998 - 08/31/2018 (PI)
American Parkinson Disease Association, Inc.


APDA Advanced Center for Parkinson's Research
09/01/1998 - 08/31/2018 (PI)
American Parkinson Disease Association, Inc.


A Randomized, Double Blind, Placebo Controlled Study of SD-809 Extended Release for the Treatment of Chorea associated with Huntington Disease
10/01/2013 - 01/31/2018 (PI)
Auspex Pharmaceuticals, Inc.


American Parkinson Disease Association (APDA) Staff Grant
02/01/2016 - 08/31/2016 (PI)
American Parkinson Disease Association, Inc.


Sphermine
07/01/2003 - 10/31/2015 (PI)
Berlex


A Phase 2B, Twelve-week Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study, To determine the Safety, Tolerability and Efficacy of Three Doses of Once Daily P2B001
02/21/2014 - 02/20/2015 (PI)
Pharma Two B Ltd.


Information and Referral Center
09/01/2013 - 08/31/2014 (PI)
American Parkinson Disease Association, Inc.


A phase 2b, randomized, double-blind placebo-controlled study investigating the efficacy and safety of inhaled CVT-301 (Levodopa Inhalation Powder) in Parkinson's disease patients with motor response
04/01/2013 - 12/31/2013 (PI)
Civitas Therapeutics, Inc.


Phase 2 Randomized Double-Blind, Placebo-Controlled Parallel Group Multicenter Study to Evaluate the Safety Tolerability and Efficacy of ADX48621 in the Treatment of Levodopa Induced Dyskinesia in Pat
10/01/2011 - 09/30/2013 (PI)
Addex Pharmaceuticals


A phase III, double-blind, placebo-controlled randomised trial to determine the efficacy and safety of a low (50 mg/day) and high (100 mg/day) dose of safinamide, as add-on therapy, in subjects w
09/01/2010 - 08/31/2011 (PI)
Serono Inc


Showing 10 of 37 results. Show All Results

228PD201
01/09/2018 - 01/09/2021 (PI)
Biogen, Inc

IN11004OLE
11/17/2017 - 11/17/2020 (PI)
Intec Pharma Ltd.

The Parkinson's Progression Markers Initiave (PPMI)
04/19/2010 - 03/31/2020 (PI)
Michael J. Fox Foundation

Intec Pharma IPH11004-11004X
04/05/2017 - 04/05/2019 (PI)
Intec Pharma Ltd.

Phase 3, Randomized, Double Blind, Placebo Controlled Study
02/01/2015 - 02/01/2019 (PI)
Civitas Therapeutics, Inc.

12 Month Dose Level Blinded Study Investigating the safety and efficacy of CVT-301
02/01/2015 - 02/01/2019 (PI)
Civitas Therapeutics, Inc.

A Prospective Registry Study in a Global Huntington's Disease Cohort (Enroll-HD)
08/16/2012 - 02/01/2019 (PI)
CHDI Foundation

Eltoprazine in the Treatment of Levodopa Induced Dyskinesia in Patients with Parkinsons's Disease
07/21/2015 - 09/30/2018 (PI)
Amarantus Bioscience Holdings, Inc.

Protocol CVT-301-009
07/26/2016 - 07/26/2018 (PI)
Acorda Therapeutics, INC

INO-PD-P#-2014 SURE
06/07/2016 - 06/20/2018 (PI)
Mass General Hosp NIH-NINDS

Showing 10 of 16 results. Show All Results


Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Goldman JG, Andrews H, Amara A, Naito A, Alcalay RN, Shaw LM, Taylor P, Xie T, Tuite P, Henchcliffe C, Hogarth P, Frank S, Saint-Hilaire MH, Frasier M, Arnedo V, Reimer AN, Sutherland M, Swanson-Fischer C, Gwinn K, Kang UJ. Cerebrospinal fluid, plasma, and saliva in the BioFIND study: Relationships among biomarkers and Parkinson's disease Features. Mov Disord. 2018 Feb; 33(2):282-288. PMID: 29205509.
     
  2. Frank S, Testa CM, Stamler D, Kayson E, Davis C, Edmondson MC, Kinel S, Leavitt B, Oakes D, O'Neill C, Vaughan C, Goldstein J, Herzog M, Snively V, Whaley J, Wong C, Suter G, Jankovic J, Jimenez-Shahed J, Hunter C, Claassen DO, Roman OC, Sung V, Smith J, Janicki S, Clouse R, Saint-Hilaire M, Hohler A, Turpin D, James RC, Rodriguez R, Rizer K, Anderson KE, Heller H, Carlson A, Criswell S, Racette BA, Revilla FJ, Nucifora F, Margolis RL, Ong M, Mendis T, Mendis N, Singer C, Quesada M, Paulsen JS, Brashers-Krug T, Miller A, Kerr J, Dubinsky RM, Gray C, Factor SA, Sperin E, Molho E, Eglow M, Evans S, Kumar R, Reeves C, Samii A, Chouinard S, Beland M, Scott BL, Hickey PT, Esmail S, Fung WL, Gibbons C, Qi L, Colcher A, Hackmyer C, McGarry A, Klos K, Gudesblatt M, Fafard L, Graffitti L, Schneider DP, Dhall R, Wojcieszek JM, LaFaver K, Duker A, Neefus E, Wilson-Perez H, Shprecher D, Wall P, Blindauer KA, Wheeler L, Boyd JT, Houston E, Farbman ES, Agarwal P, Eberly SW, Watts A, Tariot PN, Feigin A, Evans S, Beck C, Orme C, Edicola J, Christopher E. Effect of Deutetrabenazine on Chorea Among Patients With Huntington Disease: A Randomized Clinical Trial. JAMA. 2016 Jul 5; 316(1):40-50.View Related Profiles. PMID: 27380342; DOI: 10.1001/jama.2016.8655;.
     
  3. Ellis T, Tickle-Degnen L, Saint-Hilaire M. Physiotherapy and Occupational Therapy and Mild to Moderate Parkinson Disease. JAMA Neurol. 2016 Jul 01; 73(7):892-3. PMID: 27243424; DOI: 10.1001/jamaneurol.2016.1274;.
     
  4. Ma HI, Saint-Hilaire M, Thomas CA, Tickle-Degnen L. Stigma as a key determinant of health-related quality of life in Parkinson's disease. Qual Life Res. 2016 Dec; 25(12):3037-3045.View Related Profiles. PMID: 27259581.
     
  5. Gunnery SD, Habermann B, Saint-Hilaire M, Thomas CA, Tickle-Degnen L. The Relationship between the Experience of Hypomimia and Social Wellbeing in People with Parkinson's Disease and their Care Partners. J Parkinsons Dis. 2016 Jun 03; 6(3):625-30.View Related Profiles. PMID: 27285568; PMCID: PMC5003752; DOI: 10.3233/JPD-160782;.
     
  6. LeWitt PA, Hauser RA, Grosset DG, Stocchi F, Saint-Hilaire MH, Ellenbogen A, Leinonen M, Hampson NB, DeFeo-Fraulini T, Freed MI, Kieburtz KD. A randomized trial of inhaled levodopa (CVT-301) for motor fluctuations in Parkinson's disease. Mov Disord. 2016 Sep; 31(9):1356-65. PMID: 27090868; DOI: 10.1002/mds.26611;.
     
  7. Biglan KM, Shoulson I, Kieburtz K, Oakes D, Kayson E, Shinaman MA, Zhao H, Romer M, Young A, Hersch S, Penney J, Marder K, Paulsen J, Quaid K, Siemers E, Tanner C, Mallonee W, Suter G, Dubinsky R, Gray C, Nance M, Bundlie S, Radtke D, Kostyk S, Baic C, Caress J, Walker F, Hunt V, O'Neill C, Chouinard S, Factor S, Greenamyre T, Wood-Siverio C, Corey-Bloom J, Song D, Peavy G, Moskowitz C, Wesson M, Samii A, Bird T, Lipe H, Blindauer K, Marshall F, Zimmerman C, Goldstein J, Rosas D, Novak P, Caviness J, Adler C, Duffy A, Wheelock V, Tempkin T, Richman D, Seeberger L, Albin R, Chou KL, Racette B, Perlmutter JS, Perlman S, Bordelon Y, Martin W, Wieler M, Leavitt B, Raymond L, Decolongon J, Clarke L, Jankovic J, Hunter C, Hauser RA, Sanchez-Ramos J, Furtado S, Suchowersky O, Klimek ML, Guttman M, Sethna R, Feigin A, Cox M, Shannon B, Percy A, Dure L, Harrison M, Johnson W, Higgins D, Molho E, Nickerson C, Evans S, Hobson D, Singer C, Galvez-Jimenez N, Shannon K, Comella C, Ross C, Saint-Hilaire MH, Testa C, Rosenblatt A, Hogarth P, Weiner W, Como P, Kumar R, Cotto C, Stout J, Brocht A, Watts A, Eberly S, Weaver C, Foroud T, Gusella J, MacDonald M, Myers R, Fahn S, Shults C. Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials. JAMA Neurol. 2016 Jan; 73(1):102-10.View Related Profiles. PMID: 26569098; DOI: 10.1001/jamaneurol.2015.2736;.
     
  8. Sparrow D, DeAngelis TR, Hendron K, Thomas CA, Saint-Hilaire M, Ellis T. Highly Challenging Balance Program Reduces Fall Rate in Parkinson Disease. J Neurol Phys Ther. 2016 Jan; 40(1):24-30.View Related Profiles. PMID: 26655100; DOI: 10.1097/NPT.0000000000000111;.
     
  9. Taylor KM, Saint-Hilaire MH, Sudarsky L, Simon DK, Hersh B, Sparrow D, Hu H, Weisskopf MG. Head injury at early ages is associated with risk of Parkinson's disease. Parkinsonism Relat Disord. 2016 Feb; 23:57-61.View Related Profiles. PMID: 26725141; PMCID: PMC4787263; DOI: 10.1016/j.parkreldis.2015.12.005;.
     
  10. Zuzuárregui JR, Shah A, Saint-Hilaire MH. Clinical Reasoning: A 72-year-old man with nocturnal stridor. Neurology. 2015 Nov 3; 85(18):e136-9. PMID: 26527798; PMCID: PMC4642146; DOI: 10.1212/WNL.0000000000002088;.
     
Showing 10 of 56 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 56 publications over 22 distinct years, with a maximum of 7 publications in 2016

YearPublications
19861
19872
19931
19941
19971
19981
19992
20002
20012
20023
20032
20053
20063
20086
20103
20112
20125
20133
20143
20152
20167
20171
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Parkinson Disease
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Boston MA 02118
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