Elisha M. Wachman, MD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Dept of Pediatrics

MD, Boston University School of Medicine
BS, Georgetown University

Pronouns: she/her/hers

Dr. Wachman is an Associate Professor of Pediatrics at the BU School of Medicine and attending neonatologist at Boston Medical Center (BMC). She is currently the Director of Pediatric Academic Research at BUSM/BMC. She is a nationally recognized clinical and translational researcher with expertise in neonatal opioid withdrawal syndrome (NOWS) and substance use disorders in pregnancy. Her specific research interests include the genetics and epigenetics of NOWS, treatments for opioid use disorder (OUD) in pregnancy, and the use of non-pharmacologic care methods to improve NOWS outcomes. She is currently the principal investigator of a NIH funded study examining the safety, efficacy, pharmacokinetics, pharmacogenomics, and long-term maternal and infant outcomes of naltrexone for pregnant individuals with OUD and participates in several other NIH and foundation funded studies involving pregnant individuals with OUD / infants with NOWS. Dr. Wachman also researches perinatal COVID-19 transmission, including examination of placental and neonatal markers of inflammation.

Diversity, Equity, Inclusion and Accessibility

My research and clinical focus is on pregnant individuals with substance use disorders, a historically marginalized population who often have histories of trauma, psychiatric co-morbidities and incarceration. I have strived to create patient-centered approaches to care and to decrease stigma for this population. This includes developing a family-centered delivery experience, and continual education of trainees and staff about caring for individuals with substance use disorders in a non-stigmatized manner. In addition, I have strived for diversity in my research staff and mentees. The majority of my mentees have been women, many from underrepresented backgrounds.

The National Drug Abuse Treatment Clinical Trials Network (CTN-0080
06/01/2019 - 02/28/2024 (PI)
McLean Hospital NIH-NIDA

Safety, pharmacokinetics and efficacy of extended-release naltrexone in pregnant women with…
09/17/2018 - 05/31/2023 (PI)

MATernaL and Infant NetworK to Understand Outcomes Associated with Treatment for Opioid…
03/01/2020 - 07/31/2022 (PI)
Task Force for Global Health

The National Drug Abuse Clinical Trials Network: New England
06/01/2020 - 02/28/2022 (PI)
Yale University School of Medicine National Institute o

Neonatal Abstinence Syndrome (NAS) Research and Quality Improvement Program
12/14/2016 - 08/31/2018 (PI)
Massachusetts Health Policy Commission


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Borrelli KN, Wachman EM, Beierle JA, Taglauer ES, Jain M, Bryant CD, Zhang H. Effect of Prenatal Opioid Exposure on the Human Placental Methylome. Biomedicines. 2022 May 17; 10(5).View Related Profiles. PMID: 35625888; PMCID: PMC9138340; DOI: 10.3390/biomedicines10051150;
  2. Morrison TM, MacMillan KDL, Melvin P, Singh R, Murzycki J, Van Vleet MW, Rothstein R, O'Shea TF, Gupta M, Schiff DM, Wachman EM. Neonatal Opioid Withdrawal Syndrome: A Comparison of As-Needed Pharmacotherapy. Hosp Pediatr. 2022 May 01; 12(5):530-538.View Related Profiles. PMID: 35403199
  3. Taglauer ES, Dhole Y, Boateng J, Snyder-Cappione J, Parker SE, Clarke K, Juttukonda L, Devera J, Hunnewell J, Barnett E, Jia H, Yarrington C, Sabharwal V, Wachman EM. Evaluation of maternal-infant dyad inflammatory cytokines in pregnancies affected by maternal SARS-CoV-2 infection in early and late gestation. J Perinatol. 2022 Oct; 42(10):1319-1327.View Related Profiles. PMID: 35449446; PMCID: PMC9022897; DOI: 10.1038/s41372-022-01391-9;
  4. Juttukonda LJ, Wachman EM, Boateng J, Jain M, Benarroch Y, Taglauer ES. Decidual immune response following COVID-19 during pregnancy varies by timing of maternal SARS-CoV-2 infection. J Reprod Immunol. 2022 Jun; 151:103501.View Related Profiles. PMID: 35231754; PMCID: PMC8867981; DOI: 10.1016/j.jri.2022.103501;
  5. MacMillan KDL, Morrison TM, Melvin P, Diop H, Gupta M, Wachman EM. Impact of Coronavirus Disease-2019 on Hospital Care for Neonatal Opioid Withdrawal Syndrome. J Pediatr. 2022 Jun; 245:47-55. PMID: 35131283; PMCID: PMC8816795; DOI: 10.1016/j.jpeds.2022.02.001;
  6. Taglauer ES, Wachman EM, Juttukonda L, Klouda T, Kim J, Wang Q, Ishiyama A, Hackam DJ, Yuan K, Jia H. Acute Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy Is Associated with Placental Angiotensin-Converting Enzyme 2 Shedding. Am J Pathol. 2022 04; 192(4):595-603.View Related Profiles. PMID: 35090860; PMCID: PMC8789383; DOI: 10.1016/j.ajpath.2021.12.011;
  7. Taglauer ES, Wachman EM, Juttukonda L, Klouda T, Kim J, Wang Q, Ishiyama A, Hackam DJ, Yuan K, Jia H. Acute SARS-CoV-2 infection in pregnancy is associated with placental ACE-2 shedding. bioRxiv. 2021 Nov 22.View Related Profiles. PMID: 34845447; PMCID: PMC8629190; DOI: 10.1101/2021.11.19.469335;
  8. Boateng JO, Wachman EM, Turcinovic J, Devera J, Jain M, Jean-Sicard S, Woodard E, Cruikshank A, Sinha B, Bartolome R, Barnett ED, Parker MG, Yarrington C, Connor JH, Taglauer E, Sabharwal V. SARS-CoV-2 in infant urine and fecal samples after in utero COVID-19 exposure. Pediatr Res. 2022 Aug; 92(2):536-540.View Related Profiles. PMID: 34718351; PMCID: PMC8556813; DOI: 10.1038/s41390-021-01822-x;
  9. Devlin LA, Young LW, Kraft WK, Wachman EM, Czynski A, Merhar SL, Winhusen T, Jones HE, Poindexter BB, Wakschlag LS, Salisbury AL, Matthews AG, Davis JM. Neonatal opioid withdrawal syndrome: a review of the science and a look toward the use of buprenorphine for affected infants. J Perinatol. 2022 Mar; 42(3):300-306. PMID: 34556799; PMCID: PMC8459143; DOI: 10.1038/s41372-021-01206-3;
  10. Borrelli KN, Yao EJ, Yen WW, Phadke RA, Ruan QT, Chen MM, Kelliher JC, Langan CR, Scotellaro JL, Babbs RK, Beierle JC, Logan RW, Johnson WE, Wachman EM, Cruz-Martín A, Bryant CD. Sex Differences in Behavioral and Brainstem Transcriptomic Neuroadaptations following Neonatal Opioid Exposure in Outbred Mice. eNeuro. 2021 Sep-Oct; 8(5).View Related Profiles. PMID: 34479978; PMCID: PMC8454922; DOI: 10.1523/ENEURO.0143-21.2021;
Showing 10 of 61 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 61 publications over 12 distinct years, with a maximum of 12 publications in 2021


Can New Medication Styles for Opioid Addiction Prevent Relapse in New Parents?

HealthCity 9/22/2022

COVID-19 infection during pregnancy causes high inflammation in newborns, study says

Study Finds 4/28/2022

Study shows how inflammation from COVID-19 during pregnancy could impact long-term infant health

News Medical 4/26/2022

Researchers discover how the placenta may be blocking SARS-CoV-2 transmission to babies during pregnancy

Medical Xpress 1/31/2022

Mandatory Reporting Law Is Harmful for Pregnant People with Substance Use Disorder

HealthCity 6/29/2021

Pregnant people infected with SARS-CoV-2 appear to be at higher risk of developing severe cases of COVID-19 than infected people who are not pregnant.

Technology.org 1/5/2021

Human Fetuses Can Contract SARS-CoV-2, but It’s Rare

The Scientist 1/1/2021

Researchers Identify Proteins That Prevent COVID-19 Transmission Through the Placenta

HealthCity 9/15/2020

Implementing Eat, Sleep, Console Model Improves Neonatal Opioid Withdrawal Syndrome Outcomes

HealthCity 9/2/2020

Pilot Study: Treating Opioid Use Disorder with Naltrexone During Pregnancy Shows Promise

MultiBrief Exclusive 9/19/2019

Using Naltrexone During Pregnancy Can Benefit Infants, Moms

The Fix 8/21/2019

BMC: Naltrexone Promising Treatment for Opioid Use Disorder During Pregnancy

Essential Hospitals 8/14/2019

Naltrexone May Offer Advantages Over Buprenorphine to Treat Opioid Use Disorder During Pregnancy

HealthCity 8/13/2019

Promotion to Associate Professor for 18 Medical Campus Faculty

BU Today 6/14/2019

‘Hugs Not Drugs’ for Opioid-Dependent Newborns

MedPage Today 4/30/2019

To The Moon And Back, SENSE Host Newborne Substance Abuse Event

Wicked Local Carve 4/23/2019

Buprenorphine Optimal Treatment For Neonatal Abstinence Syndrome

Healio 2/2/2019

Buprenorphine May Best Morphine for Treating NAS

MedPage Today 1/22/2019

‘I Know I Can Do It’: New Hampshire Moms In Recovery Learn New Methods Of Supporting Babies

The Boston Globe 10/15/2018

Amid opioid crisis, treatment for dependent infants evolves

The Columbian 8/27/2018

Babies Born Dependent On Opioids Need Touch, Not Tech

WBUR 8/16/2018

2021 Boston Combined Residency Program in Pediatrics: Jerome Klein Teaching Excellence Award
2018 America's Essential Hospitals Gage Award
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Neonatal Opioid Withdrawal Syndrome
Substance Use Disorders

I am an Associate Professor of Pediatrics and Director of Pediatric Academic Research at BUSM/BMC. My research expertise is in substance use disorders in pregnancy and neonatal opioid withdrawal syndrome, with most of my work focused on clinical and translational research.

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

801 Albany Street, Room 2003
Boston MA 02119
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