Chad Mire | Profiles RNS

Chad Mire, PhD

Assistant Professor

University of Texas Medical Branch

Microbiology & Immunology

Websites

	UTMB Department of Microbiology and Immunology
	LinkedIn

My research focuses on understanding host-pathogen interactions of lethal negative strand RNA viruses. Using reverse genetics we characterize viruses in vitro and in vivo elucidating what is important for virus replication thereby potentially revealing pathways for small molecule inhibitors or therapeutics which can be targeted for protective benefit.

Postdoctoral Fellow (previously held)
Boston University Chobanian & Avedisian School of Medicine

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Prasad AN, Woolsey C, Geisbert JB, Agans KN, Borisevich V, Deer DJ, Mire CE, Cross RW, Fenton KA, Broder CC, Geisbert TW. Resistance of Cynomolgus Monkeys to Nipah and Hendra Virus Disease Is Associated With Cell-Mediated and Humoral Immunity. J Infect Dis. 2020 05 11; 221(Suppl 4):S436-S447. PMID: 32022850; PMCID: PMC7213570; DOI: 10.1093/infdis/jiz613;

Mire CE, Chan YP, Borisevich V, Cross RW, Yan L, Agans KN, Dang HV, Veesler D, Fenton KA, Geisbert TW, Broder CC. A Cross-Reactive Humanized Monoclonal Antibody Targeting Fusion Glycoprotein Function Protects Ferrets Against Lethal Nipah Virus and Hendra Virus Infection. J Infect Dis. 2020 05 11; 221(Suppl 4):S471-S479. PMID: 31686101; PMCID: PMC7199785; DOI: 10.1093/infdis/jiz515;

Geisbert JB, Borisevich V, Prasad AN, Agans KN, Foster SL, Deer DJ, Cross RW, Mire CE, Geisbert TW, Fenton KA. An Intranasal Exposure Model of Lethal Nipah Virus Infection in African Green Monkeys. J Infect Dis. 2020 05 11; 221(Suppl 4):S414-S418. PMID: 31665362; PMCID: PMC7213566; DOI: 10.1093/infdis/jiz391;

Prasad AN, Agans KN, Sivasubramani SK, Geisbert JB, Borisevich V, Mire CE, Lawrence WS, Fenton KA, Geisbert TW. A Lethal Aerosol Exposure Model of Nipah Virus Strain Bangladesh in African Green Monkeys. J Infect Dis. 2020 05 11; 221(Suppl 4):S431-S435. PMID: 31665351

Satterfield BA, Cross RW, Fenton KA, Borisevich V, Agans KN, Deer DJ, Graber J, Basler CF, Geisbert TW, Mire CE. Correction for Satterfield et al., "Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets". J Virol. 2020 03 31; 94(8). PMID: 32234799; PMCID: PMC7108828; DOI: 10.1128/JVI.00059-20;

Woolsey C, Jankeel A, Matassov D, Geisbert JB, Agans KN, Borisevich V, Cross RW, Deer DJ, Fenton KA, Latham TE, Gerardi CS, Mire CE, Eldridge JH, Messaoudi I, Geisbert TW. Immune correlates of postexposure vaccine protection against Marburg virus. Sci Rep. 2020 02 20; 10(1):3071. PMID: 32080323; PMCID: PMC7033120; DOI: 10.1038/s41598-020-59976-3;

Cross RW, Xu R, Matassov D, Hamm S, Latham TE, Gerardi CS, Nowak RM, Geisbert JB, Ota-Setlik A, Agans KN, Luckay A, Witko SE, Soukieh L, Deer DJ, Mire CE, Feldmann H, Happi C, Fenton KA, Eldridge JH, Geisbert TW. Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death. J Clin Invest. 2020 01 02; 130(1):539-551. PMID: 31820871; PMCID: PMC6934204; DOI: 10.1172/JCI131958;

Satterfield BA, Borisevich V, Foster SL, Rodriguez SE, Cross RW, Fenton KA, Agans KN, Basler CF, Geisbert TW, Mire CE. Antagonism of STAT1 by Nipah virus P gene products modulates disease course but not lethal outcome in the ferret model. Sci Rep. 2019 11 13; 9(1):16710. PMID: 31723221; PMCID: PMC6853903; DOI: 10.1038/s41598-019-53037-0;

Woolsey C, Menicucci AR, Cross RW, Luthra P, Agans KN, Borisevich V, Geisbert JB, Mire CE, Fenton KA, Jankeel A, Anand S, Ebihara H, Geisbert TW, Messaoudi I, Basler CF. A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge. Cell Rep. 2019 09 17; 28(12):3032-3046.e6. PMID: 31533029; PMCID: PMC6886687; DOI: 10.1016/j.celrep.2019.08.047;

Jasenosky LD, Cadena C, Mire CE, Borisevich V, Haridas V, Ranjbar S, Nambu A, Bavari S, Soloveva V, Sadukhan S, Cassell GH, Geisbert TW, Hur S, Goldfeld AE. The FDA-Approved Oral Drug Nitazoxanide Amplifies Host Antiviral Responses and Inhibits Ebola Virus. iScience. 2019 Sep 27; 19:1279-1290. PMID: 31402258; PMCID: PMC6831822; DOI: 10.1016/j.isci.2019.07.003;

Showing 10 of 71 results. Show More

Cross RW, Hastie KM, Mire CE, Robinson JE, Geisbert TW, Branco LM, Ollmann Saphire E, Garry RF. Antibody therapy for Lassa fever. Curr Opin Virol. 2019 08; 37:97-104. PMID: 31401518

Mire CE, Geisbert JB, Agans KN, Versteeg KM, Deer DJ, Satterfield BA, Fenton KA, Geisbert TW. Use of Single-Injection Recombinant Vesicular Stomatitis Virus Vaccine to Protect Nonhuman Primates Against Lethal Nipah Virus Disease. Emerg Infect Dis. 2019 06; 25(6):1144-1152. PMID: 31107231; PMCID: PMC6537706; DOI: 10.3201/eid2506.181620;

Rodriguez SE, Cross RW, Fenton KA, Bente DA, Mire CE, Geisbert TW. Vesicular Stomatitis Virus-Based Vaccine Protects Mice against Crimean-Congo Hemorrhagic Fever. Sci Rep. 2019 05 23; 9(1):7755. PMID: 31123310; PMCID: PMC6533279; DOI: 10.1038/s41598-019-44210-6;

Versteeg K, Menicucci AR, Woolsey C, Mire CE, Geisbert JB, Cross RW, Agans KN, Jeske D, Messaoudi I, Geisbert TW. Author Correction: Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants. Sci Rep. 2019 May 08; 9(1):7329. PMID: 31065012; PMCID: PMC6505025; DOI: 10.1038/s41598-019-42949-6;

Marzi A, Mire CE. Current Ebola Virus Vaccine Progress. BioDrugs. 2019 Feb; 33(1):9-14. PMID: 30604389

Bornholdt ZA, Herbert AS, Mire CE, He S, Cross RW, Wec AZ, Abelson DM, Geisbert JB, James RM, Rahim MN, Zhu W, Borisevich V, Banadyga L, Gunn BM, Agans KN, Wirchnianski AS, Goodwin E, Tierney K, Shestowsky WS, Bohorov O, Bohorova N, Velasco J, Ailor E, Kim D, Pauly MH, Whaley KJ, Alter G, Walker LM, Chandran K, Zeitlin L, Qiu X, Geisbert TW, Dye JM. A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates. Cell Host Microbe. 2019 01 09; 25(1):49-58.e5. PMID: 30629918; PMCID: PMC6341996; DOI: 10.1016/j.chom.2018.12.005;

Gilchuk P, Mire CE, Geisbert JB, Agans KN, Deer DJ, Cross RW, Slaughter JC, Flyak AI, Mani J, Pauly MH, Velasco J, Whaley KJ, Zeitlin L, Geisbert TW, Crowe JE. Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates. J Infect Dis. 2018 11 22; 218(suppl_5):S565-S573. PMID: 29982718; PMCID: PMC6249568; DOI: 10.1093/infdis/jiy295;

Cross RW, Mire CE, Agans KN, Borisevich V, Fenton KA, Geisbert TW. Marburg and Ravn Viruses Fail to Cause Disease in the Domestic Ferret (Mustela putorius furo). J Infect Dis. 2018 11 22; 218(suppl_5):S448-S452. PMID: 29955887; PMCID: PMC6249574; DOI: 10.1093/infdis/jiy268;

Woolsey C, Geisbert JB, Matassov D, Agans KN, Borisevich V, Cross RW, Deer DJ, Fenton KA, Eldridge JH, Mire CE, Geisbert TW. Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates. J Infect Dis. 2018 11 22; 218(suppl_5):S582-S587. PMID: 29939296; PMCID: PMC6249565; DOI: 10.1093/infdis/jiy293;

Olsen ME, Filone CM, Rozelle D, Mire CE, Agans KN, Hensley L, Connor JH. Correction for Olsen et al., "Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication". MBio. 2018 06 05; 9(3).View Related Profiles.

Mire, Chad
Filone, Claire Marie
Rozelle, Dan
Connor, John

PMID: 29871921; PMCID: PMC5989069; DOI: 10.1128/mBio.01065-18;

Cross RW, Mire CE, Feldmann H, Geisbert TW. Post-exposure treatments for Ebola and Marburg virus infections. Nat Rev Drug Discov. 2018 May 04. PMID: 29725132

Callendret B, Vellinga J, Wunderlich K, Rodriguez A, Steigerwald R, Dirmeier U, Cheminay C, Volkmann A, Brasel T, Carrion R, Giavedoni LD, Patterson JL, Mire CE, Geisbert TW, Hooper JW, Weijtens M, Hartkoorn-Pasma J, Custers J, Grazia Pau M, Schuitemaker H, Zahn R. Correction: A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates. PLoS One. 2018; 13(4):e0196546. PMID: 29689118; PMCID: PMC5916865; DOI: 10.1371/journal.pone.0196546;

Callendret B, Vellinga J, Wunderlich K, Rodriguez A, Steigerwald R, Dirmeier U, Cheminay C, Volkmann A, Brasel T, Carrion R, Giavedoni LD, Patterson JL, Mire CE, Geisbert TW, Hooper JW, Weijtens M, Hartkoorn-Pasma J, Custers J, Grazia Pau M, Schuitemaker H, Zahn R. A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates. PLoS One. 2018; 13(2):e0192312. PMID: 29462200; PMCID: PMC5819775; DOI: 10.1371/journal.pone.0192312;

Cross RW, Mire CE, Feldmann H, Geisbert TW. Post-exposure treatments for Ebola and Marburg virus infections. Nat Rev Drug Discov. 2018 06; 17(6):413-434. PMID: 29375139

Matassov D, Mire CE, Latham T, Geisbert JB, Xu R, Ota-Setlik A, Agans KN, Kobs DJ, Wendling MQS, Burnaugh A, Rudge TL, Sabourin CL, Egan MA, Clarke DK, Geisbert TW, Eldridge JH. Single-Dose Trivalent VesiculoVax Vaccine Protects Macaques from Lethal Ebolavirus and Marburgvirus Challenge. J Virol. 2018 02 01; 92(3). PMID: 29142131; PMCID: PMC5774882; DOI: 10.1128/JVI.01190-17;

Thi EP, Mire CE, Lee AC, Geisbert JB, Ursic-Bedoya R, Agans KN, Robbins M, Deer DJ, Cross RW, Kondratowicz AS, Fenton KA, MacLachlan I, Geisbert TW. siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease. J Clin Invest. 2017 12 01; 127(12):4437-4448. PMID: 29106386; PMCID: PMC5707162; DOI: 10.1172/JCI96185;

Menicucci AR, Versteeg K, Woolsey C, Mire CE, Geisbert JB, Cross RW, Agans KN, Jankeel A, Geisbert TW, Messaoudi I. Transcriptome Analysis of Circulating Immune Cell Subsets Highlight the Role of Monocytes in Zaire Ebola Virus Makona Pathogenesis. Front Immunol. 2017; 8:1372. PMID: 29123522; PMCID: PMC5662559; DOI: 10.3389/fimmu.2017.01372;

Mire CE, Cross RW, Geisbert JB, Borisevich V, Agans KN, Deer DJ, Heinrich ML, Rowland MM, Goba A, Momoh M, Boisen ML, Grant DS, Fullah M, Khan SH, Fenton KA, Robinson JE, Branco LM, Garry RF, Geisbert TW. Human-monoclonal-antibody therapy protects nonhuman primates against advanced Lassa fever. Nat Med. 2017 Oct; 23(10):1146-1149. PMID: 28869611; PMCID: PMC5719877; DOI: 10.1038/nm.4396;

Versteeg K, Menicucci AR, Woolsey C, Mire CE, Geisbert JB, Cross RW, Agans KN, Jeske D, Messaoudi I, Geisbert TW. Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants. Sci Rep. 2017 08 29; 7(1):9730. PMID: 28852031; PMCID: PMC5574898; DOI: 10.1038/s41598-017-09963-y;

Mire CE, Geisbert TW. Neutralizing the Threat: Pan-Ebolavirus Antibodies Close the Loop. Trends Mol Med. 2017 Aug; 23(8):669-671. PMID: 28697885; PMCID: PMC5718150; DOI: 10.1016/j.molmed.2017.06.008;

Daaboul GG, Freedman DS, Scherr SM, Carter E, Rosca A, Bernstein D, Mire CE, Agans KN, Hoenen T, Geisbert TW, Ünlü MS, Connor JH. Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses. PLoS One. 2017; 12(6):e0179728.View Related Profiles.

Mire, Chad
Connor, John

PMID: 28651016; PMCID: PMC5484481; DOI: 10.1371/journal.pone.0179728;

Mire CE, Geisbert JB, Borisevich V, Fenton KA, Agans KN, Flyak AI, Deer DJ, Steinkellner H, Bohorov O, Bohorova N, Goodman C, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Crowe JE, Zeitlin L, Geisbert TW. Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody. Sci Transl Med. 2017 Apr 05; 9(384). PMID: 28381540; PMCID: PMC5719873; DOI: 10.1126/scitranslmed.aai8711;

Scherr SM, Freedman DS, Agans KN, Rosca A, Carter E, Kuroda M, Fawcett HE, Mire CE, Geisbert TW, Ünlü MS, Connor JH. Disposable cartridge platform for rapid detection of viral hemorrhagic fever viruses. Lab Chip. 2017 02 28; 17(5):917-925.View Related Profiles.

Mire, Chad
Connor, John

PMID: 28194457; DOI: 10.1039/c6lc01528j;

Mire CE, Geisbert TW. Evaluation of Medical Countermeasures Against Ebolaviruses in Nonhuman Primate Models. Methods Mol Biol. 2017; 1628:293-307. PMID: 28573630

Warfield KL, Warren TK, Qiu X, Wells J, Mire CE, Geisbert JB, Stuthman KS, Garza NL, Van Tongeren SA, Shurtleff AC, Agans KN, Wong G, Callahan MV, Geisbert TW, Klose B, Ramstedt U, Treston AM. Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo. Antiviral Res. 2017 Feb; 138:22-31. PMID: 27908828

Benzine JW, Brown KM, Agans KN, Godiska R, Mire CE, Gowda K, Converse B, Geisbert TW, Mead DA, Chander Y. Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly From Blood. J Infect Dis. 2016 Oct 15; 214(suppl 3):S234-S242. PMID: 27638947; PMCID: PMC5050483; DOI: 10.1093/infdis/jiw330;

Mire CE, Geisbert JB, Agans KN, Thi EP, Lee AC, Fenton KA, Geisbert TW. Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates. J Infect Dis. 2016 Oct 15; 214(suppl 3):S367-S374. PMID: 27571900; PMCID: PMC5050484; DOI: 10.1093/infdis/jiw333;

Thi EP, Lee AC, Geisbert JB, Ursic-Bedoya R, Agans KN, Robbins M, Deer DJ, Fenton KA, Kondratowicz AS, MacLachlan I, Geisbert TW, Mire CE. Rescue of non-human primates from advanced Sudan ebolavirus infection with lipid encapsulated siRNA. Nat Microbiol. 2016 Aug 22; 1(10):16142. PMID: 27670117; PMCID: PMC5154560; DOI: 10.1038/nmicrobiol.2016.142;

Cross RW, Mire CE, Branco LM, Geisbert JB, Rowland MM, Heinrich ML, Goba A, Momoh M, Grant DS, Fullah M, Khan SH, Robinson JE, Geisbert TW, Garry RF. Treatment of Lassa virus infection in outbred guinea pigs with first-in-class human monoclonal antibodies. Antiviral Res. 2016 Sep; 133:218-222. PMID: 27531367; PMCID: PMC5032844; DOI: 10.1016/j.antiviral.2016.08.012;

Mire CE, Satterfield BA, Geisbert JB, Agans KN, Borisevich V, Yan L, Chan YP, Cross RW, Fenton KA, Broder CC, Geisbert TW. Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy. Sci Rep. 2016 08 03; 6:30916. PMID: 27484128; PMCID: PMC4971471; DOI: 10.1038/srep30916;

Olsen ME, Filone CM, Rozelle D, Mire CE, Agans KN, Hensley L, Connor JH. Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication. MBio. 2016 Jul 26; 7(4).View Related Profiles.

Mire, Chad
Filone, Claire Marie
Rozelle, Dan
Connor, John

PMID: 27460797; PMCID: PMC4981715; DOI: 10.1128/mBio.00882-16;

Satterfield BA, Cross RW, Fenton KA, Borisevich V, Agans KN, Deer DJ, Graber J, Basler CF, Geisbert TW, Mire CE. Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets. J Virol. 2016 07 15; 90(14):6326-43. PMID: 27147733; PMCID: PMC4936148; DOI: 10.1128/JVI.00215-16;

Mire CE, Geisbert JB, Agans KN, Deer DJ, Fenton KA, Geisbert TW. Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus. J Infect Dis. 2016 Oct 15; 214(suppl 3):S263-S267. PMID: 27284090; PMCID: PMC5050459; DOI: 10.1093/infdis/jiw149;

Cross RW, Mire CE, Borisevich V, Geisbert JB, Fenton KA, Geisbert TW. The Domestic Ferret (Mustela putorius furo) as a Lethal Infection Model for 3 Species of Ebolavirus. J Infect Dis. 2016 Aug 15; 214(4):565-9. PMID: 27354371; PMCID: PMC4957446; DOI: 10.1093/infdis/jiw209;

Mire CE, Geisbert TW, Feldmann H, Marzi A. Ebola virus vaccines - reality or fiction? Expert Rev Vaccines. 2016 Nov; 15(11):1421-1430. PMID: 27078187; PMCID: PMC5145306; DOI: 10.1080/14760584.2016.1178068;

Shabman RS, Shrivastava S, Tsibane T, Attie O, Jayaprakash A, Mire CE, Dilley KE, Puri V, Stockwell TB, Geisbert TW, Sachidanandam R, Basler CF. Isolation and Characterization of a Novel Gammaherpesvirus from a Microbat Cell Line. mSphere. 2016 Jan-Feb; 1(1). PMID: 27303702; PMCID: PMC4863610; DOI: 10.1128/mSphere.00070-15;

Edwards MR, Liu G, Mire CE, Sureshchandra S, Luthra P, Yen B, Shabman RS, Leung DW, Messaoudi I, Geisbert TW, Amarasinghe GK, Basler CF. Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins. Cell Rep. 2016 Feb 23; 14(7):1632-1640. PMID: 26876165; PMCID: PMC4767585; DOI: 10.1016/j.celrep.2016.01.049;

Pécheur EI, Borisevich V, Halfmann P, Morrey JD, Smee DF, Prichard M, Mire CE, Kawaoka Y, Geisbert TW, Polyak SJ. The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses. J Virol. 2016 Jan 06; 90(6):3086-92. PMID: 26739045; PMCID: PMC4810626; DOI: 10.1128/JVI.02077-15;

Whitt MA, Geisbert TW, Mire CE. Single-Vector, Single-Injection Recombinant Vesicular Stomatitis Virus Vaccines Against High-Containment Viruses. Methods Mol Biol. 2016; 1403:295-311. PMID: 27076138

Pattabhi S, Wilkins CR, Dong R, Knoll ML, Posakony J, Kaiser S, Mire CE, Wang ML, Ireton RC, Geisbert TW, Bedard KM, Iadonato SP, Loo YM, Gale M. Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway. J Virol. 2015 Dec 16; 90(5):2372-87. PMID: 26676770; PMCID: PMC4810700; DOI: 10.1128/JVI.02202-15;

Pinsky BA, Sahoo MK, Sandlund J, Kleman M, Kulkarni M, Grufman P, Nygren M, Kwiatkowski R, Baron EJ, Tenover F, Denison B, Higuchi R, Van Atta R, Beer NR, Carrillo AC, Naraghi-Arani P, Mire CE, Ranadheera C, Grolla A, Lagerqvist N, Persing DH. Analytical Performance Characteristics of the Cepheid GeneXpert Ebola Assay for the Detection of Ebola Virus. PLoS One. 2015; 10(11):e0142216. PMID: 26562786; PMCID: PMC4643052; DOI: 10.1371/journal.pone.0142216;

Meyer M, Garron T, Lubaki NM, Mire CE, Fenton KA, Klages C, Olinger GG, Geisbert TW, Collins PL, Bukreyev A. Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses. J Clin Invest. 2015 Aug 3; 125(8):3241-55.View Related Profiles.

Mire, Chad
Olinger, Gene

PMID: 26168222; PMCID: PMC4563760; DOI: 10.1172/JCI81532;

Matassov D, Marzi A, Latham T, Xu R, Ota-Setlik A, Feldmann F, Geisbert JB, Mire CE, Hamm S, Nowak B, Egan MA, Geisbert TW, Eldridge JH, Feldmann H, Clarke DK. Vaccination With a Highly Attenuated Recombinant Vesicular Stomatitis Virus Vector Protects Against Challenge With a Lethal Dose of Ebola Virus. J Infect Dis. 2015 Oct 01; 212 Suppl 2:S443-51. PMID: 26109675; PMCID: PMC4564554; DOI: 10.1093/infdis/jiv316;

Satterfield BA, Cross RW, Fenton KA, Agans KN, Basler CF, Geisbert TW, Mire CE. The immunomodulating V and W proteins of Nipah virus determine disease course. Nat Commun. 2015 Jun 24; 6:7483. PMID: 26105519; PMCID: PMC4482017; DOI: 10.1038/ncomms8483;

Cross RW, Fenton KA, Geisbert JB, Ebihara H, Mire CE, Geisbert TW. Comparison of the Pathogenesis of the Angola and Ravn Strains of Marburg Virus in the Outbred Guinea Pig Model. J Infect Dis. 2015 Oct 01; 212 Suppl 2:S258-70. PMID: 26092858; PMCID: PMC4564542; DOI: 10.1093/infdis/jiv182;

Cross RW, Fenton KA, Geisbert JB, Mire CE, Geisbert TW. Modeling the Disease Course of Zaire ebolavirus Infection in the Outbred Guinea Pig. J Infect Dis. 2015 Oct 01; 212 Suppl 2:S305-15. PMID: 26038397

Mire CE, Geisbert JB, Versteeg KM, Mamaeva N, Agans KN, Geisbert TW, Connor JH. A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs. J Infect Dis. 2015 Oct 1; 212 Suppl 2:S384-8.View Related Profiles.

Mire, Chad
Connor, John

PMID: 25957964; PMCID: PMC4564539; DOI: 10.1093/infdis/jiv126;

Thi EP, Mire CE, Lee AC, Geisbert JB, Zhou JZ, Agans KN, Snead NM, Deer DJ, Barnard TR, Fenton KA, MacLachlan I, Geisbert TW. Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates. Nature. 2015 May 21; 521(7552):362-5. PMID: 25901685; PMCID: PMC4467030; DOI: 10.1038/nature14442;

Safronetz D, Mire C, Rosenke K, Feldmann F, Haddock E, Geisbert T, Feldmann H. A recombinant vesicular stomatitis virus-based Lassa fever vaccine protects guinea pigs and macaques against challenge with geographically and genetically distinct Lassa viruses. PLoS Negl Trop Dis. 2015 Apr; 9(4):e0003736. PMID: 25884628; PMCID: PMC4401668; DOI: 10.1371/journal.pntd.0003736;

Mire CE, Matassov D, Geisbert JB, Latham TE, Agans KN, Xu R, Ota-Setlik A, Egan MA, Fenton KA, Clarke DK, Eldridge JH, Geisbert TW. Single-dose attenuated Vesiculovax vaccines protect primates against Ebola Makona virus. Nature. 2015 Apr 30; 520(7549):688-691. PMID: 25853476; PMCID: PMC4629916; DOI: 10.1038/nature14428;

Shabman RS, Jabado OJ, Mire CE, Stockwell TB, Edwards M, Mahajan M, Geisbert TW, Basler CF. Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells. MBio. 2014 Nov 04; 5(6):e02011. PMID: 25370495; PMCID: PMC4222107; DOI: 10.1128/mBio.02011-14;

Thi EP, Mire CE, Ursic-Bedoya R, Geisbert JB, Lee ACH, Agans KN, Robbins M, Deer DJ, Fenton KA, MacLachlan I, Geisbert TW. Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA. Sci Transl Med. 2014 Aug 20; 6(250):250ra116. PMID: 25143366; PMCID: PMC4502585; DOI: 10.1126/scitranslmed.3009706;

Geisbert TW, Mire CE, Geisbert JB, Chan YP, Agans KN, Feldmann F, Fenton KA, Zhu Z, Dimitrov DS, Scott DP, Bossart KN, Feldmann H, Broder CC. Therapeutic treatment of Nipah virus infection in nonhuman primates with a neutralizing human monoclonal antibody. Sci Transl Med. 2014 Jun 25; 6(242):242ra82. PMID: 24964990; PMCID: PMC4467163; DOI: 10.1126/scitranslmed.3008929;

Mire CE, Geisbert JB, Agans KN, Satterfield BA, Versteeg KM, Fritz EA, Feldmann H, Hensley LE, Geisbert TW. Durability of a vesicular stomatitis virus-based marburg virus vaccine in nonhuman primates. PLoS One. 2014; 9(4):e94355. PMID: 24759889; PMCID: PMC3997383; DOI: 10.1371/journal.pone.0094355;

Edwards MR, Johnson B, Mire CE, Xu W, Shabman RS, Speller LN, Leung DW, Geisbert TW, Amarasinghe GK, Basler CF. The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway. Cell Rep. 2014 Mar 27; 6(6):1017-1025. PMID: 24630991; PMCID: PMC3985291; DOI: 10.1016/j.celrep.2014.01.043;

Mire CE, Geisbert JB, Agans KN, Feng YR, Fenton KA, Bossart KN, Yan L, Chan YP, Broder CC, Geisbert TW. A recombinant Hendra virus G glycoprotein subunit vaccine protects nonhuman primates against Hendra virus challenge. J Virol. 2014 May; 88(9):4624-31. PMID: 24522928; PMCID: PMC3993805; DOI: 10.1128/JVI.00005-14;

Mire CE, Geisbert JB, Marzi A, Agans KN, Feldmann H, Geisbert TW. Vesicular stomatitis virus-based vaccines protect nonhuman primates against Bundibugyo ebolavirus. PLoS Negl Trop Dis. 2013; 7(12):e2600. PMID: 24367715; PMCID: PMC3868506; DOI: 10.1371/journal.pntd.0002600;

Mire CE, Versteeg KM, Cross RW, Agans KN, Fenton KA, Whitt MA, Geisbert TW. Single injection recombinant vesicular stomatitis virus vaccines protect ferrets against lethal Nipah virus disease. Virol J. 2013 Dec 13; 10:353. PMID: 24330654; PMCID: PMC3878732; DOI: 10.1186/1743-422X-10-353;

Ursic-Bedoya R, Mire CE, Robbins M, Geisbert JB, Judge A, MacLachlan I, Geisbert TW. Protection against lethal Marburg virus infection mediated by lipid encapsulated small interfering RNA. J Infect Dis. 2014 Feb 15; 209(4):562-70. PMID: 23990568; PMCID: PMC3903369; DOI: 10.1093/infdis/jit465;

Luthra P, Ramanan P, Mire CE, Weisend C, Tsuda Y, Yen B, Liu G, Leung DW, Geisbert TW, Ebihara H, Amarasinghe GK, Basler CF. Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome. Cell Host Microbe. 2013 Jul 17; 14(1):74-84. PMID: 23870315; PMCID: PMC3875338; DOI: 10.1016/j.chom.2013.06.010;

Mire CE, Miller AD, Carville A, Westmoreland SV, Geisbert JB, Mansfield KG, Feldmann H, Hensley LE, Geisbert TW. Recombinant vesicular stomatitis virus vaccine vectors expressing filovirus glycoproteins lack neurovirulence in nonhuman primates. PLoS Negl Trop Dis. 2012; 6(3):e1567. PMID: 22448291; PMCID: PMC3308941; DOI: 10.1371/journal.pntd.0001567;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 71 publications over 9 distinct years, with a maximum of 15 publications in 2016

Bar chart showing 71 publications over 9 distinct years, with a maximum of 15 publications in 2016

Year	Publications
2012	1
2013	4
2014	6
2015	11
2016	15
2017	9
2018	9
2019	9
2020	7

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