Shinobu Matsuura, DVM, PhD
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Dept of Medicine
Cardiovascular Medicine

PhD, University of Tokyo
DVM, Universidade de São Paulo

Pronouns: she/her/hers

Shinobu Matsuura, DVM, PhD, graduated Veterinary School and completed her clinical training at the Residency Program for Internal Medicine at the University of São Paulo (USP), Brazil. Her interest in basic research led her to pursue graduate studies at the University of Tokyo, Japan, under the guidance of Dr. Hajime Tsujimoto, and postdoctoral training at the laboratory of Dr. Dong-Er Zhang at the Scripps Research Institute and at the University of California, San Diego.

Dr. Matsuura joined the laboratory of Dr. Katya Ravid at Boston University in 2011 as a postdoctoral fellow, becoming Instructor of Medicine in 2016 and Assistant Professor in 2021. Dr. Matsuura is a PI of the career development SERCA K01 award, from the Office of Research Infrastructure (ORIP)/NIH, a training mechanism specifically designed for veterinarians pursuing basic research.

Dr. Matsuura has a career-long interest in hematology research, which emerged from her experience treating canine patients with hematological malignancies. She has multiple first author and co-author publications in the journal Blood, a leading journal in the field of hematology. Dr. Matsuura’s major research focus is stem cell biology and the mechanisms of cell differentiation, or, more precisely, the de-regulation of those processes in malignancy. Dr. Matsuura’s strength lies in her ability to combine clinical and basic science knowledge to make the most effective use of animal models to carry out preclinical research of significant translational potential.

The bone marrow extracellular matrix: scaffold of hematopoiesis
02/01/2019 - 01/31/2024 (PI)
NIH/Office of the Director


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Karagianni A, Matsuura S, Gerstenfeld LC, Ravid K. Inhibition of Osteoblast Differentiation by JAK2V617F Megakaryocytes Derived From Male Mice With Primary Myelofibrosis. Front Oncol. 2022; 12:929498.View Related Profiles. PMID: 35880162; PMCID: PMC9307716; DOI: 10.3389/fonc.2022.929498;
  2. Matsuura S, Balduini A, Onisto M. Editorial: Mechanisms of Cell Adhesion in Hematopoietic Stem Cells. Front Cell Dev Biol. 2021; 9:826554. PMID: 34993206; PMCID: PMC8724261; DOI: 10.3389/fcell.2021.826554;
  3. Yang X, Chitalia SV, Matsuura S, Ravid K. Integrins and their role in megakaryocyte development and function. Exp Hematol. 2022 02; 106:31-39.View Related Profiles. PMID: 34910941; PMCID: PMC8795491; DOI: 10.1016/j.exphem.2021.11.007;
  4. Lim KH, Matsuura S, Xu B. Editorial: Novel Treatment Strategies for Myeloproliferative Neoplasms. Front Oncol. 2021; 11:762928. PMID: 34604100; PMCID: PMC8479092; DOI: 10.3389/fonc.2021.762928;
  5. Matsuura S, Thompson CR, Belghasem ME, Bekendam RH, Piasecki A, Leiva O, Ray A, Italiano J, Yang M, Merill-Skoloff G, Chitalia VC, Flaumenhaft R, Ravid K. Platelet Dysfunction and Thrombosis in JAK2V617F-Mutated Primary Myelofibrotic Mice. Arterioscler Thromb Vasc Biol. 2020 10; 40(10):e262-e272.View Related Profiles. PMID: 32814440; PMCID: PMC7605151; DOI: 10.1161/ATVBAHA.120.314760;
  6. Matsuura S, Thompson CR, Ng SK, Ward CM, Karagianni A, Mazzeo C, Malara A, Balduini A, Ravid K. Adhesion to fibronectin via a5ß1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis. Blood. 2020 06 18; 135(25):2286-2291.View Related Profiles. PMID: 32294178; PMCID: PMC7316217; DOI: 10.1182/blood.2019004230;
  7. Leiva O, Ng SK, Matsuura S, Chitalia V, Lucero H, Findlay A, Turner C, Jarolimek W, Ravid K. Novel lysyl oxidase inhibitors attenuate hallmarks of primary myelofibrosis in mice. Int J Hematol. 2019 Dec; 110(6):699-708.View Related Profiles. PMID: 31637674; PMCID: PMC7503219; DOI: 10.1007/s12185-019-02751-6;
  8. Sano S, Wang Y, Yura Y, Sano M, Oshima K, Yang Y, Katanasaka Y, Min KD, Matsuura S, Ravid K, Mohi G, Walsh K. JAK2V617F -Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure. JACC Basic Transl Sci. 2019 Oct; 4(6):684-697.View Related Profiles. PMID: 31709318; PMCID: PMC6834960; DOI: 10.1016/j.jacbts.2019.05.013;
  9. Kolachalama VB, Shashar M, Alousi F, Shivanna S, Rijal K, Belghasem ME, Walker J, Matsuura S, Chang GH, Gibson CM, Dember LM, Francis JM, Ravid K, Chitalia VC. Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans. J Am Soc Nephrol. 2018 03; 29(3):1063-1072.View Related Profiles. PMID: 29343519; PMCID: PMC5827608; DOI: 10.1681/ASN.2017080929;
  10. Shashar M, Belghasem ME, Matsuura S, Walker J, Richards S, Alousi F, Rijal K, Kolachalama VB, Balcells M, Odagi M, Nagasawa K, Henderson JM, Gautam A, Rushmore R, Francis J, Kirchhofer D, Kolandaivelu K, Sherr DH, Edelman ER, Ravid K, Chitalia VC. Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk. Sci Transl Med. 2017 Nov 22; 9(417).View Related Profiles. PMID: 29167396; PMCID: PMC5854487; DOI: 10.1126/scitranslmed.aam8475;
Showing 10 of 37 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 37 publications over 16 distinct years, with a maximum of 6 publications in 2012


2015 American Society of Biochemistry and Molecular Biology (ASBMB): Best Thematic Poster Award
2010 Annual Meeting of the American Society of Hematology (ASH): Travel Award
2007 Federation of American Societies for Experimental Biology (FASEB), : Best Poster Award
2005 Japanese College of Veterinary Internal Medicine: Best Science Presentation Award

I believe that an individual mentoring experience is essential for research education.
I have experience in undergraduate and graduate mentoring. My teaching philosophy is to create an inquisitive environment to nurture curiosity and learning.

Available to Mentor as: (Review Mentor Role Definitions):
  • Diversity Mentor
  • Education Mentor
  • Project Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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