Sayon Roy, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Endocrinology, Diabetes & Nutrition

PhD, Boston University
MS, University of Kalyani



My expertise is in understanding the pathogenesis of diabetic microvascular complications. In particular, studying the effect of high glucose in retinal endothelial cells, pericytes, and Muller cell gene expression.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences


Professor
Boston University School of Medicine
Ophthalmology


Boston Medical Center




Thickening of Basement Membrane in Diabetic Retinopathy
01/01/2004 - 12/31/2009 (PI)
NIH/National Eye Institute
3 R01 EY14702 04S1

Towards Development of a Primate Model of Diabetic Retinopathy
03/31/2006 - 03/31/2008 (PI)
Pearl Vision Foundation

Role of Basement Membrane Thickening in Vascular Complications of Diabetes
07/01/2002 - 06/30/2006 (PI)
American Diabetes Association

Basement Membrane Thickening in Diabetic Retinopathy
04/01/1999 - 06/30/2004 (PI)
NIH/National Eye Institute
5 R29 EY11990 06

Gene Delivery and Regulation of Abnormal Gene Expression in Diabetes
02/01/2000 - 02/28/2002 (PI)
National Medical Technology Testbed

Role of Extracellular Matrix Accumulation in the Vascular Complications of Diabetes
04/01/1999 - 12/31/2001 (PI)
American Diabetes Association


Mitochondrial fragmentation and dysfunction in diabetic retinopathy
02/01/2018 - 01/31/2023 (PI)
NIH-NEI
1R01EY027082-01A1

Role of Abnormal lysyl oxidase in the pathogenesis of diabetic retinopathy
04/01/2016 - 03/31/2020 (PI)
NIH-NEI
5R01EY025528-04

Novel Therapies to inhibit diabetic retinopathy
04/01/2015 - 03/31/2020 (PI)
Case Western Reserve University NIH-NEI
5R24EY024864-04

Assessment of Therapeutic Potential of Danegaptide/Rotigaptide in Diabetic Retinopathy
08/29/2014 - 04/30/2018 (PI)
Zealand Pharma

Role of Intercellular Communication in Pathogenesis of Diabetic Retinopathy
01/01/2009 - 12/31/2014 (PI)
NIH-NEI
5R01 EY018218-05

Diabetic mamoset, a potential non-human primate model of diabetic retinopathy
03/01/2008 - 02/28/2010 (PI)
Juvenile Diab Fdtn

Effect of Insulin against High Glucose-induced apoptosis in retinal vascular cells
06/01/2006 - 08/31/2006 (PI)
Fight for Sight



Yr Title Project-Sub Proj Pubs
2018 Mitochondrial fragmentation and dysfunction in diabetic retinopathy 1R01EY027082-01A1
2018 Role of Abnormal lysyl oxidase in the pathogenesis of diabetic retinopathy 5R01EY025528-04
2017 Role of Abnormal lysyl oxidase in the pathogenesis of diabetic retinopathy 5R01EY025528-03
2016 Role of Abnormal lysyl oxidase in the pathogenesis of diabetic retinopathy 5R01EY025528-02
2015 Role of Abnormal lysyl oxidase in the pathogenesis of diabetic retinopathy 1R01EY025528-01
2013 Role of intercellular communication in pathogenesis of diabetic retinopathy 5R01EY018218-05 12
2012 Role of intercellular communication in pathogenesis of diabetic retinopathy 5R01EY018218-04 12
2011 DEVELOPMENT OF A NON-HUMAN PRIMATE MODEL OF DIABETIC RETINOPATHY 5P51RR000168-50-7604 243
2011 Role of intercellular communication in pathogenesis of diabetic retinopathy 5R01EY018218-03 12
2011 Role of intercellular communication in pathogenesis of diabetic retinopathy 5R01EY018218-03 12
Showing 10 of 28 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Consigli A, Papanastasiou A, Roquelaure D, Wuarin R, Roy S, Thumann G, Chronopoulos A. [Changes in Retinal Vascular Caliber after Intravitreal Aflibercept Treatment for Diabetic Macular Oedema]. Klin Monbl Augenheilkd. 2018 Aug 02. PMID: 30071565.
     
  2. Kim D, Mouritzen U, Larsen BD, Roy S. Inhibition of Cx43 gap junction uncoupling prevents high glucose-induced apoptosis and reduces excess cell monolayer permeability in retinal vascular endothelial cells. Exp Eye Res. 2018 Aug; 173:85-90. PMID: 29750972.
     
  3. Zhang L, Song W, Shao D, Zhang S, Desai M, Ness S, Roy S, Yi J. Volumetric fluorescence retinal imaging in vivo over a 30-degree field of view by oblique scanning laser ophthalmoscopy (oSLO). Biomed Opt Express. 2018 01 01; 9(1):25-40.View Related Profiles. PMID: 29359085.
     
  4. Roy S, Kim D, Lim R. Cell-cell communication in diabetic retinopathy. Vision Res. 2017 10; 139:115-122. PMID: 28583293.
     
  5. Roy S, Jiang JX, Li AF, Kim D. Connexin channel and its role in diabetic retinopathy. Prog Retin Eye Res. 2017 Nov; 61:35-59. PMID: 28602949.
     
  6. Tien T, Zhang J, Muto T, Kim D, Sarthy VP, Roy S. High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2017 Jun 01; 58(7):2915-2921.View Related Profiles. PMID: 28586916.
     
  7. Kim D, Mecham RP, Trackman PC, Roy S. Downregulation of Lysyl Oxidase Protects Retinal Endothelial Cells From High Glucose-Induced Apoptosis. Invest Ophthalmol Vis Sci. 2017 May 01; 58(5):2725-2731.View Related Profiles. PMID: 28538980.
     
  8. Roy S, Kern TS, Song B, Stuebe C. Mechanistic Insights into Pathological Changes in the Diabetic Retina: Implications for Targeting Diabetic Retinopathy. Am J Pathol. 2017 Jan; 187(1):9-19. PMID: 27846381; DOI: 10.1016/j.ajpath.2016.08.022;.
     
  9. Hymowitz MB, Chang D, Feinberg EB, Roy S. Increased Intraocular Pressure and Hyperglycemic Level in Diabetic Patients. PLoS One. 2016; 11(3):e0151833.View Related Profiles. PMID: 27002725; PMCID: PMC4803191; DOI: 10.1371/journal.pone.0151833;.
     
  10. Roy S, Amin S, Roy S. Retinal fibrosis in diabetic retinopathy. Exp Eye Res. 2016 Jan; 142:71-5. PMID: 26675403; PMCID: PMC4683353; DOI: 10.1016/j.exer.2015.04.004;.
     
Showing 10 of 49 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 49 publications over 17 distinct years, with a maximum of 7 publications in 2013

YearPublications
20022
20033
20041
20052
20061
20071
20083
20092
20106
20114
20121
20137
20142
20154
20163
20175
20182
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Diabetic microangiopathy
Contact for Mentoring:


650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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