Richard Wainford, PhD
Associate Professor
Boston University School of Medicine
Dept of Pharmacology & Experimental Therapeutics

PhD, University of Aberdeen




Background:
Dr Wainford obtained a Bachelors in Zoology from the University of Wales, Cardiff in 1999. Dr Wainford undertook his Graduate training in the Laboratory of Molecular Pharmacology and Toxicology in the Department of Medicine and Therapeutics at the University of Aberdeen School of Medicine under the guidance of Professor Hawksworth, earning a PhD in Molecular Pharmacology in 2004. Dr. Wainford then completed a 2-year post-doctoral fellowship in the Department of Pharmacology at the Louisiana State University Health Sciences Center in New Orleans in Cardiovascular & Renal Pharmacology under the mentorship of Dr. Kapusta. Dr. Wainford then became an Instructor of Pharmacology in 2008, remaining in the laboratory of Dr. Kapusta until his promotion to the rank of Assistant Professor in 2010. Dr. Wainford joined the Department of Pharmacology & Experimental Therapeutics at the Boston University School of Medicine and the Whitaker Cardiovascular Institute in 2011 as an Assistant Professor.

Research Summary:
Dr. Wainford is the director of the Laboratory of Cardio-Renal Research. Dr. Wainford’s research interests focus on the central neural control of fluid and electrolyte homeostasis and blood pressure regulation. Dr. Wainford’s laboratory utilizes an integrated physiological, pharmacological, molecular, and gene-targeting approach to investigate the anti-hypertensive role(s) of central G-alpha-subunit proteins in the endogenous GPCR-activated pathways that regulate central sympatheticoutflow, fluid and electrolyte homeostasis, and systemic blood pressure regulation in salt-resistant and salt-sensitive animal models.The major goal of Dr. Wainford’s research is identifying the underlying pathophysiology of and potential treatments for hypertension. Current studies concern the role of central G-alpha subunit protein gated pathways in mediating the neural control of kidney function and systemic arterial blood pressure.

Associate Professor
Boston University School of Medicine
Medicine
Cardiovascular Medicine

Member
Boston University
Whitaker Cardiovascular Institute


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences



2014 The American Physiology Society: Arthur C. Guyton Award for Excellence in Integrative Physiology
2014 Howard Hughes Medical Institute (HHMI): Summer Research Program Award
2013 American Heart Association Council for High Blood Pressure: Research Harry Goldblatt New Investigator
2013 The American Physiological Society Central Nervous System: New Investigator Award
2013 Endocrine Society: Early Investigator Award
2013 The American Physiological Society: Shih-Chun Wang Young Investigator Award
2012 International Society of Hypertension: New Investigator of the Month (December)
2012 The American Physiological Society: Dean Franklin Young Investigator Award
2011 The American Physiological Society: Research Career Enhancement Award


Aging and hypertension: Integrated renal and sympathetic control of blood pressure
09/30/2019 - 05/31/2024 (PI)
NIH/National Institute on Aging
1R01AG062515-01A1

Neural control of the kidney and long-term blood pressure regulation
06/01/2018 - 05/31/2022 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL139867-02

Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressure
05/01/2018 - 02/28/2022 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL141406-02

Aging and hypertension: Integrated renal and sympathetic control of blood pressure
09/15/2018 - 08/31/2020 (PI)
NIH/National Institute on Aging
1R56AG057687-01A1

Neural Control of the Kidney and Blood Pressure Regulation
07/01/2017 - 06/30/2019 (PI)
American Heart Association


Mentoring in neural and Cardiorenal Pathophysiology
07/01/2016 - 06/30/2019 (PI)
American Heart Association


Brain G-alpha subunit protein mediated neural control of blood pressure
10/01/2011 - 07/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL107330-05

Brain G-Alpha Subunit Protein Mediated Neural Control of Blood Pressure
06/01/2016 - 05/31/2018 (PI)
NIH/National Heart, Lung, and Blood Institute
5K02HL112718-05

Brain G-Alpha Subunit Protein Mediated Neural Control of Blood Pressure
08/20/2013 - 05/31/2016 (PI)
NIH/National Heart, Lung, and Blood Institute
5K02HL112718-03



Title


Yr Title Project-Sub Proj Pubs
2020 Aging and hypertension: Integrated renal and sympathetic control of blood pressure 5R01AG062515-02
2020 Neural control of the kidney and long-term blood pressure regulation 5R01HL139867-03 3
2020 Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressure 5R01HL141406-03 4
2020 Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressure 5R01HL141406-03 4
2019 Aging and hypertension: Integrated renal and sympathetic control of blood pressure 1R01AG062515-01A1
2019 Neural control of the kidney and long-term blood pressure regulation 5R01HL139867-02 3
2019 Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressure 5R01HL141406-02 4
2018 Aging and hypertension: Integrated renal and sympathetic control of blood pressure 1R56AG057687-01A1 3
2018 Neural control of the kidney and long-term blood pressure regulation 1R01HL139867-01A1 3
2018 Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressure 1R01HL141406-01 4
Showing 10 of 21 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Poulter NR, Borghi C, Burger D, Castillo RR, Damasceno A, Ito S, Jose AP, Kruger R, Morgan T, Nilsson PM, Schlaich MP, Schutte AE, Stergiou G, Unger T, Wainford RD, Beaney T. May Measurement Month 2018: results of blood pressure screening from 41 countries. Eur Heart J Suppl. 2020 Aug; 22(Suppl H):H1-H4. PMID: 32884454
     
  2. Chaudhary P, Wainford RD. Association of urinary sodium and potassium excretion with systolic blood pressure in the Dietary Approaches to Stop Hypertension Sodium Trial. J Hum Hypertens. 2020 Jul 13.View Related Profiles. PMID: 32661268
     
  3. Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, Ramirez A, Schlaich M, Stergiou GS, Tomaszewski M, Wainford RD, Williams B, Schutte AE. 2020 International Society of Hypertension global hypertension practice guidelines. J Hypertens. 2020 Jun; 38(6):982-1004. PMID: 32371787
     
  4. Beaney T, Schutte AE, Stergiou GS, Borghi C, Burger D, Charchar F, Cro S, Diaz A, Damasceno A, Espeche W, Jose AP, Khan N, Kokubo Y, Maheshwari A, Marin MJ, More A, Neupane D, Nilsson P, Patil M, Prabhakaran D, Ramirez A, Rodriguez P, Schlaich M, Steckelings UM, Tomaszewski M, Unger T, Wainford R, Wang J, Williams B, Poulter NR. May Measurement Month 2019: The Global Blood Pressure Screening Campaign of the International Society of Hypertension. Hypertension. 2020 08; 76(2):333-341. PMID: 32419505
     
  5. Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, Ramirez A, Schlaich M, Stergiou GS, Tomaszewski M, Wainford RD, Williams B, Schutte AE. 2020 International Society of Hypertension Global Hypertension Practice Guidelines. Hypertension. 2020 Jun; 75(6):1334-1357. PMID: 32370572
     
  6. Kruger R, Brunström M, Burger D, Charchar F, Climie R, Mirabito Colafella KM, Kempny P, Korostovtseva L, Marques FZ, Picone D, Romero C, Steckelings UM, Velkoska E, Wainford R, Wynne BM, Zanuzzi MG. Highlights from the International Society of Hypertension's New Investigators Network during 2019. J Hypertens. 2020 May; 38(5):968-973. PMID: 32238785
     
  7. Carmichael CY, Kuwabara JT, Pascale CL, Moreira JD, Mahne SE, Kapusta DR, Rosene DL, Williams JS, Cunningham JT, Wainford RD. Hypothalamic Paraventricular Nucleus Gai2 (Guanine Nucleotide-Binding Protein Alpha Inhibiting Activity Polypeptide 2) Protein-Mediated Neural Control of the Kidney and the Salt Sensitivity of Blood Pressure. Hypertension. 2020 Apr; 75(4):1002-1011.View Related Profiles. PMID: 32148128
     
  8. Moreira JD, Chaudhary P, Frame AA, Puleo F, Nist KM, Abkin EA, Moore TL, George JC, Wainford RD. Inhibition of microglial activation in rats attenuates paraventricular nucleus inflammation in Gai2 protein-dependent, salt-sensitive hypertension. Exp Physiol. 2019 12; 104(12):1892-1910.View Related Profiles. PMID: 31631436
     
  9. Frame AA, Puleo F, Kim K, Walsh KR, Faudoa E, Hoover RS, Wainford RD. Sympathetic regulation of NCC in norepinephrine-evoked salt-sensitive hypertension in Sprague-Dawley rats. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1623-F1636.View Related Profiles. PMID: 31608673
     
  10. Frame AA, Carmichael CY, Kuwabara JT, Cunningham JT, Wainford RD. Role of the afferent renal nerves in sodium homeostasis and blood pressure regulation in rats. Exp Physiol. 2019 08; 104(8):1306-1323.View Related Profiles. PMID: 31074108
     
Showing 10 of 46 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 46 publications over 13 distinct years, with a maximum of 9 publications in 2015

YearPublications
20071
20083
20091
20101
20124
20131
20144
20159
20167
20172
20182
20194
20207

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700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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