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PhD, University of Aberdeen
BSc, University of Wales

Websites

	Pharmacology & Experimental Therapeutics Faculty
	Laboratory for Cardiovascular-Renal Research
	Whitaker Cardiovascular Institute Training Program
	LinkedIn

ORCID : 0000-0003-2830-5618

BU Research
NIH RePORTER Research

Multidisciplinary Training in Cardiovascular Research
07/01/2016 - 06/30/2023 (Multi-PI)
PI: Richard Wainford, PhD
NIH/National Heart, Lung, and Blood Institute
5T32HL007224-45

Aging and hypertension: Integrated renal and sympathetic control of blood pressure
09/30/2019 - 06/01/2023 (PI)
NIH/National Institute on Aging
5R01AG062515-05

Age-related Hypertension and Vascular Cognitive Impairment
02/01/2022 - 05/31/2023 (Multi-PI)
PI: Richard Wainford, PhD
NIH/National Institute on Aging
5R01AG075963-02

Neural control of the kidney and long-term blood pressure regulation
06/01/2018 - 05/31/2023 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL139867-04

Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressure
05/01/2018 - 05/31/2023 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL141406-04

Aging and hypertension: Integrated renal and sympathetic control of blood pressure
09/15/2018 - 08/31/2020 (PI)
NIH/National Institute on Aging
1R56AG057687-01A1

Porter Physiology Development Fellowship - Sympathetic Nervous System Regulation of the NCC in Salt Sensitive Hypertension (Franco Puleo)
09/01/2019 - 04/30/2020 (Key Person / Mentor)
PI: Franco Puleo
The American Physiological Society

Sympathetic Nervous System regulation of the NCC in Salt Sensitive Hypertension
07/01/2019 - 03/24/2020 (Key Person / Mentor)
PI: Franco Puleo
American Society Nephrology Foundation for Kidney Research

Neural Control of the Kidney and Blood Pressure Regulation
07/01/2017 - 06/30/2019 (PI)
American Heart Association

Mentoring in neural and Cardiorenal Pathophysiology
07/01/2016 - 06/30/2019 (PI)
American Heart Association

Showing 10 of 13 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2023	Age-related Hypertension and Vascular Cognitive Impairment	5R01AG075963-02
2023	Aging and hypertension: Integrated renal and sympathetic control of blood pressure	5R01AG062515-05
2022	Age-related Hypertension and Vascular Cognitive Impairment	1R01AG075963-01
2022	Aging and hypertension: Integrated renal and sympathetic control of blood pressure	5R01AG062515-04
2021	Aging and hypertension: Integrated renal and sympathetic control of blood pressure	5R01AG062515-03
2021	Neural control of the kidney and long-term blood pressure regulation	7R01HL139867-05
2021	Neural control of the kidney and long-term blood pressure regulation	5R01HL139867-04	3
2021	Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressure	7R01HL141406-05
2021	Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressure	5R01HL141406-04	4
2020	Aging and hypertension: Integrated renal and sympathetic control of blood pressure	5R01AG062515-02

Showing 10 of 32 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Charchar FJ, Prestes PR, Mills C, Ching SM, Neupane D, Marques FZ, Sharman JE, Vogt L, Burrell LM, Korostovtseva L, Zec M, Patil M, Schultz MG, Wallen MP, Renna NF, Islam SMS, Hiremath S, Gyeltshen T, Chia YC, Gupta A, Schutte AE, Klein B, Borghi C, Browning CJ, Czesnikiewicz-Guzik M, Lee HY, Itoh H, Miura K, Brunström M, Campbell NRC, Akinnibossun OA, Veerabhadrappa P, Wainford RD, Kruger R, Thomas SA, Komori T, Ralapanawa U, Cornelissen VA, Kapil V, Li Y, Zhang Y, Jafar TH, Khan N, Williams B, Stergiou G, Tomaszewski M. Lifestyle management of hypertension: International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension. J Hypertens. 2024 Jan 01; 42(1):23-49. PMID: 37712135

Gkousioudi A, Razzoli M, Moreira JD, Wainford RD, Zhang Y. Renal denervation restores biomechanics of carotid arteries in a rat model of hypertension. Res Sq. 2023 Sep 05. PMID: 37720022

Schutte AE, Jafar TH, Poulter NR, Damasceno A, Khan NA, Nilsson PM, Alsaid J, Neupane D, Kario K, Beheiry H, Brouwers S, Burger D, Charchar FJ, Cho MC, Guzik TJ, Haji Al-Saedi GF, Ishaq M, Itoh H, Jones ESW, Khan T, Kokubo Y, Kotruchin P, Muxfeldt E, Odili A, Patil M, Ralapanawa U, Romero CA, Schlaich MP, Shehab A, Mooi CS, Steckelings UM, Stergiou G, Touyz RM, Unger T, Wainford RD, Wang JG, Williams B, Wynne BM, Tomaszewski M. Addressing global disparities in blood pressure control: perspectives of the International Society of Hypertension. Cardiovasc Res. 2023 Mar 31; 119(2):381-409. PMID: 36219457; PMCID: PMC9619669; DOI: 10.1093/cvr/cvac130;

Gnanenthiran SR, Borghi C, Burger D, Caramelli B, Charchar F, Chirinos JA, Cohen JB, Cremer A, Di Tanna GL, Duvignaud A, Freilich D, Gommans DHF, Gracia-Ramos AE, Murray TA, Pelorosso F, Poulter NR, Puskarich MA, Rizas KD, Rothlin R, Schlaich MP, Schreinlecher M, Steckelings UM, Sharma A, Stergiou GS, Tignanelli CJ, Tomaszewski M, Unger T, van Kimmenade RRJ, Wainford RD, Williams B, Rodgers A, Schutte AE. Renin-Angiotensin System Inhibitors in Patients With COVID-19: A Meta-Analysis of Randomized Controlled Trials Led by the International Society of Hypertension. J Am Heart Assoc. 2022 Sep 06; 11(17):e026143. PMID: 36000426; PMCID: PMC9496439; DOI: 10.1161/JAHA.122.026143;

Amraei R, Moreira JD, Wainford RD. Central Gai2 Protein Mediated Neuro-Hormonal Control of Blood Pressure and Salt Sensitivity. Front Endocrinol (Lausanne). 2022; 13:895466.View Related Profiles.

Moreira, Jesse
Wainford, Richard

PMID: 35837296; PMCID: PMC9275552; DOI: 10.3389/fendo.2022.895466;

Campbell NRC, Whelton PK, Orias M, Wainford RD, Cappuccio FP, Ide N, Neal B, Cohn J, Cobb LK, Webster J, Trieu K, He FJ, McLean RM, Blanco-Metzler A, Woodward M, Khan N, Kokubo Y, Nederveen L, Arcand J, MacGregor GA, Owolabi MO, Lisheng L, Parati G, Lackland DT, Charchar FJ, Williams B, Tomaszewski M, Romero CA, Champagne B, L'Abbe MR, Weber MA, Schlaich MP, Fogo A, Feigin VL, Akinyemi R, Inserra F, Menon B, Simas M, Neves MF, Hristova K, Pullen C, Pandeya S, Ge J, Jalil JE, Wang JG, Wideimsky J, Kreutz R, Wenzel U, Stowasser M, Arango M, Protogerou A, Gkaliagkousi E, Fuchs FD, Patil M, Chan AW, Nemcsik J, Tsuyuki RT, Narasingan SN, Sarrafzadegan N, Ramos ME, Yeo N, Rakugi H, Ramirez AJ, Álvarez G, Berbari A, Kim CI, Ihm SH, Chia YC, Unurjargal T, Park HK, Wahab K, McGuire H, Dashdorj NJ, Ishaq M, Ona DID, Mercado-Asis LB, Prejbisz A, Leenaerts M, Simão C, Pinto F, Almustafa BA, Spaak J, Farsky S, Lovic D, Zhang XH. 2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action. J Hum Hypertens. 2023 Jun; 37(6):428-437. PMID: 35581323; PMCID: PMC9110933; DOI: 10.1038/s41371-022-00690-0;

Gkousioudi A, Yu X, Ferruzzi J, Qian J, Wainford RD, Seta F, Zhang Y. Biomechanical Properties of Mouse Carotid Arteries With Diet-Induced Metabolic Syndrome and Aging. Front Bioeng Biotechnol. 2022; 10:862996.View Related Profiles.

Seta, Francesca
Wainford, Richard

PMID: 35392404; PMCID: PMC8980683; DOI: 10.3389/fbioe.2022.862996;

Frame AA, Nist KM, Kim K, Kuwabara JT, Wainford RD. Natriuresis During an Acute Intravenous Sodium Chloride Infusion in Conscious Sprague Dawley Rats Is Mediated by a Blood Pressure-Independent a1-Adrenoceptor-Mediated Mechanism. Front Physiol. 2021; 12:784957.View Related Profiles.

Frame, Alissa
Wainford, Richard

PMID: 35111076; PMCID: PMC8802910; DOI: 10.3389/fphys.2021.784957;

Moreira JD, Nist KM, Carmichael CY, Kuwabara JT, Wainford RD. Sensory Afferent Renal Nerve Activated Gai2 Subunit Proteins Mediate the Natriuretic, Sympathoinhibitory and Normotensive Responses to Peripheral Sodium Challenges. Front Physiol. 2021; 12:771167.View Related Profiles.

Carmichael, Casey
Moreira, Jesse
Wainford, Richard

PMID: 34916958; PMCID: PMC8669768; DOI: 10.3389/fphys.2021.771167;

Chaudhary P, Velkoska E, Wainford RD. An exploratory analysis of comparative plasma metabolomic and lipidomic profiling in salt-sensitive and salt-resistant individuals from The Dietary Approaches to Stop Hypertension Sodium Trial. J Hypertens. 2021 10 01; 39(10):1972-1981.View Related Profiles.

Chaudhary, Parul
Wainford, Richard

PMID: 34001808; PMCID: PMC8429079; DOI: 10.1097/HJH.0000000000002904;

Showing 10 of 61 results. Show More

Farris CW, Killiany RJ, O'Donoghue E, Koo BB, Wainford RD, Moss MB, Rosene DL, Moore TL. The relationship of age and hypertension with cognition and gray matter cerebral blood volume in a rhesus monkey model of human aging. Behav Neurosci. 2021 Oct; 135(5):680-692.View Related Profiles.

Koo, Bang-bon
Farris, Chad
Rosene, Douglas
Moss, Mark
Wainford, Richard
Killiany, Ronald
Moore, Tara

PMID: 34197136

Gnanenthiran SR, Borghi C, Burger D, Charchar F, Poulter NR, Schlaich MP, Steckelings UM, Stergiou G, Tomaszewski M, Unger T, Wainford RD, Williams B, Rodgers A, Schutte AE. Prospective meta-analysis protocol on randomised trials of renin-angiotensin system inhibitors in patients with COVID-19: an initiative of the International Society of Hypertension. BMJ Open. 2021 02 16; 11(2):e043625. PMID: 33593784; PMCID: PMC7887864; DOI: 10.1136/bmjopen-2020-043625;

Chaudhary P, Wainford RD. Neuroanatomical characterization of Gai2-expressing neurons in the hypothalamic paraventricular nucleus of male and female Sprague-Dawley rats. Physiol Genomics. 2021 01 01; 53(1):12-21.View Related Profiles.

Chaudhary, Parul
Wainford, Richard

PMID: 33252993; PMCID: PMC7847047; DOI: 10.1152/physiolgenomics.00097.2020;

Puleo F, Kim K, Frame AA, Walsh KR, Ferdaus MZ, Moreira JD, Comsti E, Faudoa E, Nist KM, Abkin E, Wainford RD. Sympathetic Regulation of the NCC (Sodium Chloride Cotransporter) in Dahl Salt-Sensitive Hypertension. Hypertension. 2020 11; 76(5):1461-1469.View Related Profiles.

Frame, Alissa
Puleo, Franco
Moreira, Jesse
Walsh, Kathryn
Wainford, Richard

PMID: 32981364; PMCID: PMC7727920; DOI: 10.1161/HYPERTENSIONAHA.120.15928;

Poulter NR, Borghi C, Burger D, Castillo RR, Damasceno A, Ito S, Jose AP, Kruger R, Morgan T, Nilsson PM, Schlaich MP, Schutte AE, Stergiou G, Unger T, Wainford RD, Beaney T. May Measurement Month 2018: results of blood pressure screening from 41 countries. Eur Heart J Suppl. 2020 Aug; 22(Suppl H):H1-H4. PMID: 32884454; PMCID: PMC7455278; DOI: 10.1093/eurheartj/suaa013;

Chaudhary P, Wainford RD. Association of urinary sodium and potassium excretion with systolic blood pressure in the Dietary Approaches to Stop Hypertension Sodium Trial. J Hum Hypertens. 2021 07; 35(7):577-587.View Related Profiles.

Chaudhary, Parul
Wainford, Richard

PMID: 32661268; PMCID: PMC7854834; DOI: 10.1038/s41371-020-0375-8;

Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, Ramirez A, Schlaich M, Stergiou GS, Tomaszewski M, Wainford RD, Williams B, Schutte AE. 2020 International Society of Hypertension global hypertension practice guidelines. J Hypertens. 2020 06; 38(6):982-1004. PMID: 32371787

Beaney T, Schutte AE, Stergiou GS, Borghi C, Burger D, Charchar F, Cro S, Diaz A, Damasceno A, Espeche W, Jose AP, Khan N, Kokubo Y, Maheshwari A, Marin MJ, More A, Neupane D, Nilsson P, Patil M, Prabhakaran D, Ramirez A, Rodriguez P, Schlaich M, Steckelings UM, Tomaszewski M, Unger T, Wainford R, Wang J, Williams B, Poulter NR. May Measurement Month 2019: The Global Blood Pressure Screening Campaign of the International Society of Hypertension. Hypertension. 2020 08; 76(2):333-341. PMID: 32419505

Unger T, Borghi C, Charchar F, Khan NA, Poulter NR, Prabhakaran D, Ramirez A, Schlaich M, Stergiou GS, Tomaszewski M, Wainford RD, Williams B, Schutte AE. 2020 International Society of Hypertension Global Hypertension Practice Guidelines. Hypertension. 2020 06; 75(6):1334-1357. PMID: 32370572

Kruger R, Brunström M, Burger D, Charchar F, Climie R, Mirabito Colafella KM, Kempny P, Korostovtseva L, Marques FZ, Picone D, Romero C, Steckelings UM, Velkoska E, Wainford R, Wynne BM, Zanuzzi MG. Highlights from the International Society of Hypertension's New Investigators Network during 2019. J Hypertens. 2020 05; 38(5):968-973. PMID: 32238785; PMCID: PMC8589118; DOI: 10.1097/HJH.0000000000002365;

Carmichael CY, Kuwabara JT, Pascale CL, Moreira JD, Mahne SE, Kapusta DR, Rosene DL, Williams JS, Cunningham JT, Wainford RD. Hypothalamic Paraventricular Nucleus Gai2 (Guanine Nucleotide-Binding Protein Alpha Inhibiting Activity Polypeptide 2) Protein-Mediated Neural Control of the Kidney and the Salt Sensitivity of Blood Pressure. Hypertension. 2020 04; 75(4):1002-1011.View Related Profiles.

Carmichael, Casey
Rosene, Douglas
Moreira, Jesse
Williams, Jonathan
Wainford, Richard
Mahne, Sarah

PMID: 32148128; PMCID: PMC7329357; DOI: 10.1161/HYPERTENSIONAHA.119.13777;

Frame AA, Farquhar WB, Latulippe ME, McDonough AA, Wainford RD, Wynne BM. Moving the Needle on Hypertension: What Knowledge Is Needed? Nutr Today. 2019 Nov-Dec; 54(6):248-256.View Related Profiles.

Frame, Alissa
Wainford, Richard

PMID: 34092814; PMCID: PMC8174552; DOI: 10.1097/nt.0000000000000375;

Moreira JD, Chaudhary P, Frame AA, Puleo F, Nist KM, Abkin EA, Moore TL, George JC, Wainford RD. Inhibition of microglial activation in rats attenuates paraventricular nucleus inflammation in Gai2 protein-dependent, salt-sensitive hypertension. Exp Physiol. 2019 12; 104(12):1892-1910.View Related Profiles.

Frame, Alissa
Puleo, Franco
Moreira, Jesse
Chaudhary, Parul
Wainford, Richard
Moore, Tara

PMID: 31631436; PMCID: PMC6884700; DOI: 10.1113/EP087924;

Frame AA, Puleo F, Kim K, Walsh KR, Faudoa E, Hoover RS, Wainford RD. Sympathetic regulation of NCC in norepinephrine-evoked salt-sensitive hypertension in Sprague-Dawley rats. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1623-F1636.View Related Profiles.

Frame, Alissa
Puleo, Franco
Walsh, Kathryn
Wainford, Richard

PMID: 31608673; PMCID: PMC6960786; DOI: 10.1152/ajprenal.00264.2019;

Frame AA, Carmichael CY, Kuwabara JT, Cunningham JT, Wainford RD. Role of the afferent renal nerves in sodium homeostasis and blood pressure regulation in rats. Exp Physiol. 2019 08; 104(8):1306-1323.View Related Profiles.

Frame, Alissa
Carmichael, Casey
Wainford, Richard

PMID: 31074108; PMCID: PMC6675646; DOI: 10.1113/EP087700;

Poulter NR, Borghi C, Castillo RR, Charchar FJ, Ramirez AJ, Schlaich MP, Schutte AE, Stergiou G, Unger T, Wainford RD, Beaney T. May Measurement Month 2017: Results of 39 national blood pressure screening programmes. Eur Heart J Suppl. 2019 Apr; 21(Suppl D):D1-D4. PMID: 31043862; PMCID: PMC6479430; DOI: 10.1093/eurheartj/suz055;

Zhang X, Frame AA, Williams JS, Wainford RD. GNAI2 polymorphic variance associates with salt sensitivity of blood pressure in the Genetic Epidemiology Network of Salt Sensitivity study. Physiol Genomics. 2018 09 01; 50(9):724-725.View Related Profiles.

Frame, Alissa
Williams, Jonathan
Wainford, Richard
Zhang, Xiaoling

PMID: 29906209; PMCID: PMC6172609; DOI: 10.1152/physiolgenomics.00141.2017;

Frame AA, Wainford RD. Mechanisms of altered renal sodium handling in age-related hypertension. Am J Physiol Renal Physiol. 2018 07 01; 315(1):F1-F6.View Related Profiles.

Frame, Alissa
Wainford, Richard

PMID: 29442548; PMCID: PMC6087788; DOI: 10.1152/ajprenal.00594.2017;

Wainford RD. How to Reduce Dietary Salt Intake: Just Add Spice? Hypertension. 2017 12; 70(6):1087-1088. PMID: 29089369; PMCID: PMC6629461; DOI: 10.1161/HYPERTENSIONAHA.117.10025;

Frame AA, Wainford RD. Renal sodium handling and sodium sensitivity. Kidney Res Clin Pract. 2017 Jun; 36(2):117-131.View Related Profiles.

Frame, Alissa
Wainford, Richard

PMID: 28680820; PMCID: PMC5491159; DOI: 10.23876/j.krcp.2017.36.2.117;

Wainford R. ED 09-1 RENAL SODIUM HANDLING AND SALT SENSITIVITY. J Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book:e537. PMID: 27754276

Wainford R, Walsh K. OS 29-04 SYMPATHETIC NERVOUS SYSTEM REGULATION OF THE RENAL NCC AND BLOOD PRESSURE DURING HIGH DIETARY SALT INTAKE. J Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book:e253-e254. PMID: 27754152

Wainford R, Carmichael C, Walsh K. OS 11-01 Afferent renal nerve modulation of sodium homeostasis and blood pressure: A sodium sensitive PVN Gai2 protein dependent mechanism countering the development of salt-sensitive hypertension? J Hypertens. 2016 Sep; 34 Suppl 1 - ISH 2016 Abstract Book:e74.View Related Profiles.

Carmichael, Casey
Wainford, Richard

PMID: 27753968

Carmichael, Casey
Wainford, Richard

PMID: 27643365; DOI: 10.1097/01.hjh.0000500043.00638.33;

Wainford R. ED 09-1 RENAL SODIUM HANDLING AND SALT SENSITIVITY. J Hypertens. 2016 Sep; 34 Suppl 1:e537. PMID: 27643273; DOI: 10.1097/01.hjh.0000501477.69580.2a;

Wainford R, Walsh K. OS 29-04 SYMPATHETIC NERVOUS SYSTEM REGULATION OF THE RENAL NCC AND BLOOD PRESSURE DURING HIGH DIETARY SALT INTAKE. J Hypertens. 2016 Sep; 34 Suppl 1:e253-4. PMID: 27643082; DOI: 10.1097/01.hjh.0000500576.63532.27;

Frame AA, Carmichael CY, Wainford RD. Renal Afferents. Curr Hypertens Rep. 2016 Sep; 18(9):69.View Related Profiles.

Frame, Alissa
Carmichael, Casey
Wainford, Richard

PMID: 27595156; PMCID: PMC5011151; DOI: 10.1007/s11906-016-0676-z;

Walsh KR, Kuwabara JT, Shim JW, Wainford RD. Norepinephrine-evoked salt-sensitive hypertension requires impaired renal sodium chloride cotransporter activity in Sprague-Dawley rats. Am J Physiol Regul Integr Comp Physiol. 2016 Jan 15; 310(2):R115-24.View Related Profiles.

Shim, Joon
Walsh, Kathryn
Wainford, Richard

PMID: 26608659; PMCID: PMC4796647; DOI: 10.1152/ajpregu.00514.2014;

Carmichael CY, Carmichael AC, Kuwabara JT, Cunningham JT, Wainford RD. Impaired sodium-evoked paraventricular nucleus neuronal activation and blood pressure regulation in conscious Sprague-Dawley rats lacking central Gai2 proteins. Acta Physiol (Oxf). 2016 Mar; 216(3):314-29.View Related Profiles.

Carmichael, Casey
Wainford, Richard

PMID: 26412230; PMCID: PMC4764872; DOI: 10.1111/apha.12610;

Brouwers S, Smolders I, Wainford RD, Dupont AG. Correction: Hypotensive and sympathoinhibitory responses to selective central AT2 receptor stimulation in spontaneously hypertensive rats. Clin Sci (Lond). 2015 Oct; 129(7):673. PMID: 26186745; DOI: 10.1042/CS1290673b;

Carmichael CY, Wainford RD. Brain Gai 2 -subunit proteins and the prevention of salt sensitive hypertension. Front Physiol. 2015; 6:233.View Related Profiles.

Carmichael, Casey
Wainford, Richard

PMID: 26347659; PMCID: PMC4541027; DOI: 10.3389/fphys.2015.00233;

Brouwers S, Smolders I, Wainford RD, Dupont AG. Hypotensive and sympathoinhibitory responses to selective central AT2 receptor stimulation in spontaneously hypertensive rats. Clin Sci (Lond). 2015 Jul; 129(1):81-92. PMID: 25655919; PMCID: PMC4430196; DOI: 10.1042/CS20140776;

Brouwers S, Wainford RD, Smolders I, Dupont AG. 8D.09: NIGHTTIME HYPOTENSIVE EFFECTS OF CENTRAL ANGIOTENSIN II TYPE 2 RECEPTOR STIMULATION THROUGH IMPROVED SPONTANEOUS BAROREFLEX SENSITIVITY: MORE IN SHR THAN IN WKY. J Hypertens. 2015 Jun; 33 Suppl 1:e116. PMID: 26102696; DOI: 10.1097/01.hjh.0000467663.61532.18;

Carmichael CY, Wainford RD. Hypothalamic signaling mechanisms in hypertension. Curr Hypertens Rep. 2015 May; 17(5):39.View Related Profiles.

Carmichael, Casey
Wainford, Richard

PMID: 25860531; PMCID: PMC4392165; DOI: 10.1007/s11906-015-0550-4;

Carmichael CY, Wainford RD. Impact of global versus renal-specific sympathoinhibition in aldosterone-induced hypertension: implications for medical device-based treatment of resistant hypertension. Hypertension. 2015 Jun; 65(6):1160-2.View Related Profiles.

Carmichael, Casey
Wainford, Richard

PMID: 25895585; PMCID: PMC4433421; DOI: 10.1161/HYPERTENSIONAHA.115.05228;

Veerabhadrappa P, Burger D, Brouwers S, Christofidou P, Bikai RE, Hannah-Shmouni F, Kruger R, Marques FZ, Rehman Mian MO, Montezano AC, Romero CA, Peña-Silva RA, Wainford RD, Charchar FJ, Schutte AE, Tomaszewski M. Across the globe in 4 months: two International Society of Hypertension new investigator symposia in 2014. J Hypertens. 2015 Apr; 33(4):891-3. PMID: 25668359; DOI: 10.1097/HJH.0000000000000525;

Foss JD, Wainford RD, Engeland WC, Fink GD, Osborn JW. A novel method of selective ablation of afferent renal nerves by periaxonal application of capsaicin. Am J Physiol Regul Integr Comp Physiol. 2015 Jan 15; 308(2):R112-22. PMID: 25411365; PMCID: PMC4297859; DOI: 10.1152/ajpregu.00427.2014;

Wainford RD, Carmichael CY, Pascale CL, Kuwabara JT. Gai2-protein-mediated signal transduction: central nervous system molecular mechanism countering the development of sodium-dependent hypertension. Hypertension. 2015 Jan; 65(1):178-86.View Related Profiles.

Carmichael, Casey
Wainford, Richard

PMID: 25312437; PMCID: PMC4268057; DOI: 10.1161/HYPERTENSIONAHA.114.04463;

Wainford RD. Presympathetic neuron dysfunction--time to reconsider increased intrinsic activity as the cause of neurogenic hypertension. Exp Physiol. 2014 Jul; 99(7):935-6. PMID: 24987020; PMCID: PMC4127577; DOI: 10.1113/expphysiol.2014.080077;

Wainford RD. Angiotensin AT2 receptors and the baroreflex control of renal sympathetic nerve activity. Acta Physiol (Oxf). 2014 Apr; 210(4):714-6. PMID: 24447624; PMCID: PMC4110512; DOI: 10.1111/apha.12240;

Wainford RD, Pascale CL, Kuwabara JT. Brain Gai2-subunit protein-gated pathways are required to mediate the centrally evoked sympathoinhibitory mechanisms activated to maintain sodium homeostasis. J Hypertens. 2013 Apr; 31(4):747-57. PMID: 23391983; DOI: 10.1097/HJH.0b013e32835ebd54;

Kapusta DR, Pascale CL, Kuwabara JT, Wainford RD. Central nervous system Gai2-subunit proteins maintain salt resistance via a renal nerve-dependent sympathoinhibitory pathway. Hypertension. 2013 Feb; 61(2):368-75. PMID: 23213191; PMCID: PMC3562703; DOI: 10.1161/HYPERTENSIONAHA.111.00014;

Wainford RD, Kapusta DR. Functional selectivity of central Ga-subunit proteins in mediating the cardiovascular and renal excretory responses evoked by central a(2) -adrenoceptor activation in vivo. Br J Pharmacol. 2012 May; 166(1):210-20. PMID: 21895632; PMCID: PMC3415649; DOI: 10.1111/j.1476-5381.2011.01662.x;

Kapusta DR, Pascale CL, Wainford RD. Brain heterotrimeric Gai2-subunit protein-gated pathways mediate central sympathoinhibition to maintain fluid and electrolyte homeostasis during stress. FASEB J. 2012 Jul; 26(7):2776-87. PMID: 22459149; PMCID: PMC3382099; DOI: 10.1096/fj.11-196550;

Yoshida T, Semprun-Prieto L, Wainford RD, Sukhanov S, Kapusta DR, Delafontaine P. Angiotensin II reduces food intake by altering orexigenic neuropeptide expression in the mouse hypothalamus. Endocrinology. 2012 Mar; 153(3):1411-20. PMID: 22234465; PMCID: PMC3281527; DOI: 10.1210/en.2011-1764;

Wainford RD, Kapusta DR. Hypothalamic paraventricular nucleus G alpha q subunit protein pathways mediate vasopressin dysregulation and fluid retention in salt-sensitive rats. Endocrinology. 2010 Nov; 151(11):5403-14. PMID: 20861238; PMCID: PMC2954710; DOI: 10.1210/en.2010-0345;

Wainford RD, Weaver RJ, Hawksworth GM. The immediate early genes, c-fos, c-jun and AP-1, are early markers of platinum analogue toxicity in human proximal tubular cell primary cultures. Toxicol In Vitro. 2009 Aug; 23(5):780-8. PMID: 19383537; DOI: 10.1016/j.tiv.2009.04.004;

Wainford RD, Kapusta DR. Chronic high-NaCl intake prolongs the cardiorenal responses to central N/OFQ and produces regional changes in the endogenous brain NOP receptor system. Am J Physiol Regul Integr Comp Physiol. 2009 Feb; 296(2):R280-8. PMID: 18987291; PMCID: PMC2643980; DOI: 10.1152/ajpregu.00096.2008;

Wainford RD, Kurtz K, Kapusta DR. Central G-alpha subunit protein-mediated control of cardiovascular function, urine output, and vasopressin secretion in conscious Sprague-Dawley rats. Am J Physiol Regul Integr Comp Physiol. 2008 Aug; 295(2):R535-42. PMID: 18525017; PMCID: PMC2519935; DOI: 10.1152/ajpregu.00043.2008;

Wainford RD, Weaver RJ, Stewart KN, Brown P, Hawksworth GM. Cisplatin nephrotoxicity is mediated by gamma glutamyltranspeptidase, not via a C-S lyase governed biotransformation pathway. Toxicology. 2008 Jul 30; 249(2-3):184-93. PMID: 18583013; DOI: 10.1016/j.tox.2008.05.006;

Rizzi A, Spagnolo B, Wainford RD, Fischetti C, Guerrini R, Marzola G, Baldisserotto A, Salvadori S, Regoli D, Kapusta DR, Calo G. In vitro and in vivo studies on UFP-112, a novel potent and long lasting agonist selective for the nociceptin/orphanin FQ receptor. Peptides. 2007 Jun; 28(6):1240-51. PMID: 17532097; PMCID: PMC1975813; DOI: 10.1016/j.peptides.2007.04.020;

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