Paola Massari, PhD
Adjunct Research Associate Professor
Boston University School of Medicine
Dept of Medicine
Infectious Diseases

PhD, Università degli Studi di Napoli Federico II
MSc, Università degli Studi di Napoli Federico II

I am a PhD scientist with extensive expertise in research, operations and project management in academic research and pharmaceutical industry. I have 15+ years of experience in basic and translational research in innate immunity and inflammation, bacterial pathogenesis and host response, cell biology, protein biochemistry and structure, human and veterinary vaccine design and evaluation established in both academic and industrial settings.

My research areas focus on bacteria interplay with host cells and on the mechanisms of innate immunity mediated by bacterial products. Areas of strong interest include TLR signaling and vaccine development, characterization of protein structure/functions and interactions with host cell receptors in the context of cellular and molecular immunity.

I am a strong communicator of complex scientific information to diverse audiences with excellent scientific writing/editing skills and strong experience as scientific peer reviewer. Proven ability in cost analysis and grant management. My core administrative competencies include: Strategic Vision/Planning – Project Management – Efficiency Improvement – Problem Solving – Logic/Scientific Thinking – Lab Management – Best Practices, SOP, Protocols

Boston Medical Center

A novel Th2-skewed vaccine against canine periodontitis
11/01/2014 - 10/31/2015 (PI)
American Kennel Club Canine Health Foundation

Purification of the chlamydial major outer membrane protein (MOMP) produced by cell-free (CF) synth…
12/01/2014 - 06/30/2015 (PI)
SutroVax, Inc.

Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Landig CS, Hazel A, Kellman BP, Fong JJ, Schwarz F, Agarwal S, Varki N, Massari P, Lewis NE, Ram S, Varki A. Evolution of the exclusively human pathogen Neisseria gonorrhoeae: Human-specific engagement of immunoregulatory Siglecs. Evol Appl. 2019 Feb; 12(2):337-349. PMID: 30697344.
  2. Nudel K, McClure R, Moreau M, Briars E, Abrams AJ, Tjaden B, Su XH, Trees D, Rice PA, Massari P, Genco CA. Transcriptome Analysis of Neisseria gonorrhoeae during Natural Infection Reveals Differential Expression of Antibiotic Resistance Determinants between Men and Women. mSphere. 2018 08 29; 3(3). PMID: 29950382.
  3. Madico G, Gursky O, Fairman J, Massari P. Structural and Immunological Characterization of Novel Recombinant MOMP-Based Chlamydial Antigens. Vaccines (Basel). 2017 Dec 25; 6(1).View Related Profiles. PMID: 29295593.
  4. Moreau MR, Massari P, Genco CA. The ironclad truth: how in vivo transcriptomics and in vitro mechanistic studies shape our understanding of Neisseria gonorrhoeae gene regulation during mucosal infection. Pathog Dis. 2017 Jul 31; 75(5). PMID: 28520925.
  5. Toussi DN, Wetzler LM, Liu X, Massari P. Neisseriae internalization by epithelial cells is enhanced by TLR2 stimulation. Microbes Infect. 2016 Oct; 18(10):627-638.View Related Profiles. PMID: 27373686; DOI: 10.1016/j.micinf.2016.06.001;.
  6. Stefanelli P, Neri A, Tanabe M, Fazio C, Massari P. Typing and surface charges of the variable loop regions of PorB from Neisseria meningitidis. IUBMB Life. 2016 Jun; 68(6):488-95. PMID: 27156582; DOI: 10.1002/iub.1508;.
  7. McClure R, Nudel K, Massari P, Tjaden B, Su X, Rice PA, Genco CA. The Gonococcal Transcriptome during Infection of the Lower Genital Tract in Women. PLoS One. 2015; 10(8):e0133982.View Related Profiles. PMID: 26244506; PMCID: PMC4526530; DOI: 10.1371/journal.pone.0133982;.
  8. Massari P, Gunawardana J, Liu X, Wetzler LM. Correction for Massari et al., meningococcal porin PorB prevents cellular apoptosis in a Toll-like receptor 2- and NF-?B-independent manner. Infect Immun. 2015 Aug; 83(8):3339.View Related Profiles. PMID: 26157088; PMCID: PMC4496629; DOI: 10.1128/IAI.00627-15;.
  9. Nudel K, Massari P, Genco CA. Neisseria gonorrhoeae Modulates Cell Death in Human Endocervical Epithelial Cells through Export of Exosome-Associated cIAP2. Infect Immun. 2015 Sep; 83(9):3410-7.View Related Profiles. PMID: 26077759; PMCID: PMC4534674; DOI: 10.1128/IAI.00732-15;.
  10. Kattner C, Pfennig S, Massari P, Tanabe M. One-step purification and porin transport activity of the major outer membrane proteins P2 from Haemophilus influenzae, FomA from Fusobacterium nucleatum and PorB from Neisseria meningitidis. Appl Biochem Biotechnol. 2015 Mar; 175(6):2907-15. PMID: 25575589; DOI: 10.1007/s12010-014-1473-2;.
Showing 10 of 46 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 46 publications over 23 distinct years, with a maximum of 6 publications in 2012


Available to Mentor as: (Review Mentor Role Definitions):
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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