Paola Massari, PhD
Adjunct Research Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Infectious Diseases

PhD, Università degli Studi di Napoli Federico II
MSc, Università degli Studi di Napoli Federico II
BS, Università degli Studi di Napoli Federico II

I am a PhD scientist with extensive expertise in research, operations and project management in academic research and pharmaceutical industry. I have 15+ years of experience in basic and translational research in innate immunity and inflammation, bacterial pathogenesis and host response, cell biology, protein biochemistry and structure, human and veterinary vaccine design and evaluation established in both academic and industrial settings.

My research areas focus on bacteria interplay with host cells and on the mechanisms of innate immunity mediated by bacterial products. Areas of strong interest include TLR signaling and vaccine development, characterization of protein structure/functions and interactions with host cell receptors in the context of cellular and molecular immunity.

I am a strong communicator of complex scientific information to diverse audiences with excellent scientific writing/editing skills and strong experience as scientific peer reviewer. Proven ability in cost analysis and grant management. My core administrative competencies include: Strategic Vision/Planning – Project Management – Efficiency Improvement – Problem Solving – Logic/Scientific Thinking – Lab Management – Best Practices, SOP, Protocols

Boston University
Evans Center for Interdisciplinary Biomedical Research

Boston Medical Center

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

A novel Th2-skewed vaccine against canine periodontitis
11/01/2014 - 10/31/2015 (PI)
American Kennel Club Canine Health Foundation

Purification of the chlamydial major outer membrane protein (MOMP) produced by cell-free (CF) synth…
12/01/2014 - 06/30/2015 (PI)
SutroVax, Inc.


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Roe SK, Felter B, Zheng B, Ram S, Wetzler LM, Garges E, Zhu T, Genco CA, Massari P. In Vitro Pre-Clinical Evaluation of a Gonococcal Trivalent Candidate Vaccine Identified by Transcriptomics. Vaccines (Basel). 2023 Dec 13; 11(12).View Related Profiles. PMID: 38140249; PMCID: PMC10747275; DOI: 10.3390/vaccines11121846;
  2. Costa-Lourenço APR, Su X, Le W, Yang Z, Patts GJ, Massari P, Genco CA. Epidemiological and Clinical Observations of Gonococcal Infections in Women and Prevention Strategies. Vaccines (Basel). 2021 Apr 01; 9(4). PMID: 33915835; PMCID: PMC8066387; DOI: 10.3390/vaccines9040327;
  3. Harrison OB, Cehovin A, Skett J, Jolley KA, Massari P, Genco CA, Tang CM, Maiden MCJ. Neisseria gonorrhoeae Population Genomics: Use of the Gonococcal Core Genome to Improve Surveillance of Antimicrobial Resistance. J Infect Dis. 2020 11 09; 222(11):1816-1825. PMID: 32163580; PMCID: PMC7653085; DOI: 10.1093/infdis/jiaa002;
  4. Tifrea DF, Pal S, Fairman J, Massari P, de la Maza LM. Protection against a chlamydial respiratory challenge by a chimeric vaccine formulated with the Chlamydia muridarum major outer membrane protein variable domains using the Neisseria lactamica porin B as a scaffold. NPJ Vaccines. 2020; 5:37. PMID: 32411400; PMCID: PMC7210953; DOI: 10.1038/s41541-020-0182-9;
  5. Tifrea DF, Pal S, Fairman J, Massari P, de la Maza LM. Protection against a chlamydial respiratory challenge by a chimeric vaccine formulated with the Chlamydia muridarum major outer membrane protein variable domains using the Neisseria lactamica porin B as a scaffold. NPJ Vaccines. 2020 May 08; 5(1):37. PMID: 33574319
  6. McClure R, Sunkavalli A, Balzano PM, Massari P, Cho C, Nauseef WM, Apicella MA, Genco CA. Global Network Analysis of Neisseria gonorrhoeae Identifies Coordination between Pathways, Processes, and Regulators Expressed during Human Infection. mSystems. 2020 Feb 04; 5(1). PMID: 32019834; PMCID: PMC7002116; DOI: 10.1128/mSystems.00729-19;
  7. Zhu T, McClure R, Harrison OB, Genco C, Massari P. Integrated Bioinformatic Analyses and Immune Characterization of New Neisseria gonorrhoeae Vaccine Antigens Expressed during Natural Mucosal Infection. Vaccines (Basel). 2019 Oct 17; 7(4). PMID: 31627489; PMCID: PMC6963464; DOI: 10.3390/vaccines7040153;
  8. Landig CS, Hazel A, Kellman BP, Fong JJ, Schwarz F, Agarwal S, Varki N, Massari P, Lewis NE, Ram S, Varki A. Evolution of the exclusively human pathogen Neisseria gonorrhoeae: Human-specific engagement of immunoregulatory Siglecs. Evol Appl. 2019 Feb; 12(2):337-349. PMID: 30697344; PMCID: PMC6346652; DOI: 10.1111/eva.12744;
  9. Nudel K, McClure R, Moreau M, Briars E, Abrams AJ, Tjaden B, Su XH, Trees D, Rice PA, Massari P, Genco CA. Transcriptome Analysis of Neisseria gonorrhoeae during Natural Infection Reveals Differential Expression of Antibiotic Resistance Determinants between Men and Women. mSphere. 2018 08 29; 3(3). PMID: 29950382; PMCID: PMC6021601; DOI: 10.1128/mSphereDirect.00312-18;
  10. Madico G, Gursky O, Fairman J, Massari P. Structural and Immunological Characterization of Novel Recombinant MOMP-Based Chlamydial Antigens. Vaccines (Basel). 2017 Dec 25; 6(1).View Related Profiles. PMID: 29295593; PMCID: PMC5874643; DOI: 10.3390/vaccines6010002;
Showing 10 of 53 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 53 publications over 26 distinct years, with a maximum of 6 publications in 2012


Available to Mentor as: (Review Mentor Role Definitions):
  • Co-Mentor or Peer Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
Google Map

Massari's Networks
Click the "See All" links for more information and interactive visualizations
Similar People
Same Department