Matthew Nayor, MD, MPH
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, New York University School of Medicine
MPH, Harvard School of Public Health
BA, University of Michigan at Ann Arbor

Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women's Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.

Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.

Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Preventive Medicine & Epidemiology

Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significance
08/20/2021 - 06/30/2026 (PI)
NIH/National Heart, Lung, and Blood Institute

Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise Training
08/05/2021 - 06/30/2023 (PI)
NIH/National Heart, Lung, and Blood Institute


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. McNeill J, Chernofsky A, Nayor M, Rahaghi FN, San Jose Estepar R, Washko G, Synn A, Vasan RS, O'Connor G, Larson MG, Ho JE, Lewis GD. The association of lung function and pulmonary vasculature volume with cardiorespiratory fitness in the community. Eur Respir J. 2022 Aug; 60(2).View Related Profiles. PMID: 34996832; PMCID: PMC9259762; DOI: 10.1183/13993003.01821-2021;
  2. Nayor M, Chernofsky A, Miller PE, Spartano NL, Murthy VL, Malhotra R, Houstis NE, Murabito JM, Clish CB, Larson MG, Vasan RS, Shah RV, Lewis GD. Integrative Analysis of Circulating Metabolite Levels That Correlate With Physical Activity and Cardiorespiratory Fitness. Circ Genom Precis Med. 2022 Jun; 15(3):e003592.View Related Profiles. PMID: 35536222; PMCID: PMC9233103; DOI: 10.1161/CIRCGEN.121.003592;
  3. Namasivayam M, Lau ES, Zern EK, Schoenike MW, Hardin KM, Sbarbaro JA, Cunningham TF, Farrell RM, Rouvina J, Kowal A, Bhat RR, Brooks LC, Nayor M, Shah RV, Ho JE, Malhotra R, Lewis GD. Exercise Blood Pressure in Heart Failure With Preserved and Reduced Ejection Fraction. JACC Heart Fail. 2022 Apr; 10(4):278-286. PMID: 35361448; PMCID: PMC9730937; DOI: 10.1016/j.jchf.2022.01.012;
  4. Izundegui DG, Nayor M. Metabolomics of Type 1 and Type 2 Diabetes: Insights into Risk Prediction and Mechanisms. Curr Diab Rep. 2022 02; 22(2):65-76. PMID: 35113332; PMCID: PMC8934149; DOI: 10.1007/s11892-022-01449-0;
  5. Murthy VL, Nayor M, Carnethon M, Reis JP, Lloyd-Jones D, Allen NB, Kitchen R, Piaggi P, Steffen LM, Vasan RS, Freedman JE, Clish CB, Shah RV. Circulating metabolite profile in young adulthood identifies long-term diabetes susceptibility: the Coronary Artery Risk Development in Young Adults (CARDIA) study. Diabetologia. 2022 Apr; 65(4):657-674. PMID: 35041022; PMCID: PMC8969893; DOI: 10.1007/s00125-021-05641-x;
  6. Lau ES, Panah LG, Zern EK, Liu EE, Farrell R, Schoenike MW, Namasivayam M, Churchill TW, Curreri L, Malhotra R, Nayor M, Lewis GD, Ho JE. Arterial Stiffness and Vascular Load in HFpEF: Differences Among Women and Men. J Card Fail. 2022 02; 28(2):202-211. PMID: 34955334; PMCID: PMC8840989; DOI: 10.1016/j.cardfail.2021.10.019;
  7. Zlotoff DA, Nayor M. Can We Estimate Cardiorespiratory Fitness in Breast Cancer Survivors Without Exercise? JACC CardioOncol. 2021 Dec; 3(5):692-694. PMID: 34988477; PMCID: PMC8702789; DOI: 10.1016/j.jaccao.2021.10.001;
  8. Nayor M, Chernofsky A, Spartano NL, Tanguay M, Blodgett JB, Murthy VL, Malhotra R, Houstis NE, Velagaleti RS, Murabito JM, Larson MG, Vasan RS, Shah RV, Lewis GD. Physical activity and fitness in the community: the Framingham Heart Study. Eur Heart J. 2021 11 21; 42(44):4565-4575.View Related Profiles. PMID: 34436560; PMCID: PMC8633734; DOI: 10.1093/eurheartj/ehab580;
  9. Nayor M, Shen L, Hunninghake GM, Kochunov P, Barr RG, Bluemke DA, Broeckel U, Caravan P, Cheng S, de Vries PS, Hoffmann U, Kolossváry M, Li H, Luo J, McNally EM, Thanassoulis G, Arnett DK, Vasan RS. Progress and Research Priorities in Imaging Genomics for Heart and Lung Disease: Summary of an NHLBI Workshop. Circ Cardiovasc Imaging. 2021 08; 14(8):e012943. PMID: 34387095; PMCID: PMC8486340; DOI: 10.1161/CIRCIMAGING.121.012943;
  10. Nayor M, Shah RV, Tanguay M, Blodgett JB, Chernofsky A, Miller PE, Xanthakis V, Malhotra R, Houstis NE, Velagaleti RS, Larson MG, Vasan RS, Lewis GD. Feasibility, Methodology, and Interpretation of Broad-Scale Assessment of Cardiorespiratory Fitness in a Large Community-Based Sample. Am J Cardiol. 2021 10 15; 157:56-63.View Related Profiles. PMID: 34391575; PMCID: PMC9252421; DOI: 10.1016/j.amjcard.2021.07.020;
Showing 10 of 51 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 51 publications over 11 distinct years, with a maximum of 14 publications in 2021


2021 Boston University School of Medicine: Aram Chobanian Assistant Professor of Medicine
2021 Boston University Medical Center: Boston University School of Medicine Department of Medicine Career Development Award
2018-2020 National Institutes of Health: Loan Repayment Program
2016 Brigham and Women's Hospital, Cardiovascular Medicine Division: Richard Gorlin Fellowship in Cardiovascular Medicine
2012 Johns Hopkins Hospital Osler Medical Residency: Frank L. Coulson, Jr. Award for Clinical Excellence
2009 NYU School of Medicine: Clerkship Award for Outstanding Essay in the Philosophy of Medicine
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Epidemiology, Molecular
Exercise, Physical
Heart Failure, Diastolic
Heart Failure, Systolic
Metabolic Cardiovascular Syndrome

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