Matthew Nayor, MD, MPH
Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Cardiovascular Medicine

MD, New York University School of Medicine
MPH, Harvard School of Public Health
BA, University of Michigan at Ann Arbor

Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women's Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.

Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.

Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Preventive Medicine & Epidemiology

Proteomic Profiling of Precise Exercise Pathophenotypes Across the HFpEF Spectrum
04/05/2023 - 02/28/2027 (PI)
NIH/National Heart, Lung, and Blood Institute

Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significance
08/20/2021 - 06/30/2026 (PI)
NIH/National Heart, Lung, and Blood Institute

Cardiovascular disease, metabolic syndrome, microbes and metabolites in FHS
02/01/2022 - 01/31/2026 (Subcontract PI)
Broad Institute, Inc., The NIH NHLBI

Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise Training
08/05/2021 - 06/30/2023 (PI)
NIH/National Heart, Lung, and Blood Institute


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Mi MY, Gajjar P, Walker ME, Miller P, Xanthakis V, Murthy VL, Larson MG, Vasan RS, Shah RV, Lewis GD, Nayor M. Association of healthy dietary patterns and cardiorespiratory fitness in the community. Eur J Prev Cardiol. 2023 Apr 28.View Related Profiles. PMID: 37164358
  2. Perry AS, Annis JS, Master H, Nayor M, Hughes A, Kouame A, Natarajan K, Marginean K, Murthy V, Roden DM, Harris PA, Shah R, Brittain EL. Association of Longitudinal Activity Measures and Diabetes Risk: An Analysis From the National Institutes of Health All of Us Research Program. J Clin Endocrinol Metab. 2023 Apr 13; 108(5):1101-1109. PMID: 36458881
  3. Petek BJ, Churchill TW, Gustus SK, Schoenike MW, Nayor M, Moulson N, Guseh JS, VanAtta C, Blodgett JB, Contursi M, Lewis GD, Baggish AL, Wasfy MM. Characterization of ventilatory efficiency during cardiopulmonary exercise testing in healthy athletes. Eur J Prev Cardiol. 2023 Mar 27; 30(5):e21-e24. PMID: 36321382
  4. Shah RV, Steffen LM, Nayor M, Reis JP, Jacobs DR, Allen NB, Lloyd-Jones D, Meyer K, Cole J, Piaggi P, Vasan RS, Clish CB, Murthy VL. Dietary metabolic signatures and cardiometabolic risk. Eur Heart J. 2023 Feb 14; 44(7):557-569. PMID: 36424694
  5. Mi MY, Gajjar P, Walker ME, Miller P, Xanthakis V, Murthy VL, Larson MG, Vasan RS, Shah RV, Lewis GD, Nayor M. Association of Healthy Dietary Patterns and Cardiorespiratory Fitness in the Community. medRxiv. 2023 Feb 10.View Related Profiles. PMID: 36798343; PMCID: PMC9934801; DOI: 10.1101/2023.02.09.23285714;
  6. Nayor M, Gajjar P, Murthy VL, Miller PE, Velagaleti RS, Larson MG, Vasan RS, Lewis GD, Mitchell GF, Shah RV. Blood Pressure Responses During Exercise: Physiological Correlates and Clinical Implications. Arterioscler Thromb Vasc Biol. 2023 Jan; 43(1):163-173.View Related Profiles. PMID: 36384270; PMCID: PMC9780190; DOI: 10.1161/ATVBAHA.122.318512;
  7. Perry AS, Tanriverdi K, Risitano A, Hwang SJ, Murthy VL, Nayor M, Zhao S, Levy D, Shah RV, Freedman JE. The inflammatory proteome, obesity, and medical weight loss and regain in humans. Obesity (Silver Spring). 2023 Jan; 31(1):150-158.View Related Profiles. PMID: 36334095; PMCID: PMC9923277; DOI: 10.1002/oby.23587;
  8. Gonzalez Izundegui D, Miller PE, Shah RV, Clish CB, Walker ME, Mitchell GF, Gerszten RE, Larson MG, Vasan RS, Nayor M. Response of circulating metabolites to an oral glucose challenge and risk of cardiovascular disease and mortality in the community. Cardiovasc Diabetol. 2022 Oct 15; 21(1):213.View Related Profiles. PMID: 36243866; PMCID: PMC9568897; DOI: 10.1186/s12933-022-01647-w;
  9. Shah RV, Miller P, Colangelo LA, Chernofsky A, Houstis NE, Malhotra R, Velagaleti RS, Jacobs DR, Gabriel KP, Reis JP, Lloyd-Jones DM, Clish CB, Larson MG, Vasan RS, Murthy VL, Lewis GD, Nayor M. Blood-Based Fingerprint of Cardiorespiratory Fitness and Long-Term Health Outcomes in Young Adulthood. J Am Heart Assoc. 2022 Sep 20; 11(18):e026670.View Related Profiles. PMID: 36073631; PMCID: PMC9683648; DOI: 10.1161/JAHA.122.026670;
  10. McNeill J, Chernofsky A, Nayor M, Rahaghi FN, San Jose Estepar R, Washko G, Synn A, Vasan RS, O'Connor G, Larson MG, Ho JE, Lewis GD. The association of lung function and pulmonary vasculature volume with cardiorespiratory fitness in the community. Eur Respir J. 2022 Aug; 60(2).View Related Profiles. PMID: 34996832; PMCID: PMC9259762; DOI: 10.1183/13993003.01821-2021;
Showing 10 of 60 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 60 publications over 12 distinct years, with a maximum of 14 publications in 2021


2021 Boston University School of Medicine: Aram Chobanian Assistant Professor of Medicine
2021 Boston University Medical Center: Boston University School of Medicine Department of Medicine Career Development Award
2018-2020 National Institutes of Health: Loan Repayment Program
2016 Brigham and Women's Hospital, Cardiovascular Medicine Division: Richard Gorlin Fellowship in Cardiovascular Medicine
2012 Johns Hopkins Hospital Osler Medical Residency: Frank L. Coulson, Jr. Award for Clinical Excellence
2009 NYU School of Medicine: Clerkship Award for Outstanding Essay in the Philosophy of Medicine
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Epidemiology, Molecular
Exercise, Physical
Heart Failure, Diastolic
Heart Failure, Systolic
Metabolic Cardiovascular Syndrome

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