Matthew Nayor, MD, MPH
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Cardiovascular Medicine

MD, New York University School of Medicine
MPH, Harvard School of Public Health
BA, University of Michigan at Ann Arbor



Dr. Nayor is a clinical-translational investigator and heart failure cardiologist. He received training in Internal Medicine at the Johns Hopkins Hospital Osler Medical Residency training program and Cardiology and Heart Failure and Transplantation training at Brigham and Women's Hospital. His research background includes basic science investigations, physiologic studies, and cardiovascular epidemiology focusing on the intersection of metabolic health and cardiovascular disease. His group and collaborators have studied: 1) the effect of exercise on metabolism via assaying >500 circulating metabolites; 2) physiologic determinants of fitness; 3) novel protein biomarkers of heart failure risk through broad proteomic profiling; 4) and lifestyle contributors to cardiometabolic disease and heart failure, among other topics.

Dr. Nayor has worked closely with the Framingham Heart Study for the last 8 years and currently leads community-based studies evaluating metabolic responses to discrete physiologic perturbations, such as exercise and a dietary intervention.

Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Preventive Medicine & Epidemiology



Proteomic Profiling of Precise Exercise Pathophenotypes Across the HFpEF Spectrum
04/05/2023 - 02/28/2027 (PI)
NIH/National Heart, Lung, and Blood Institute
2R01HL131029-05A1

Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significance
08/20/2021 - 06/30/2026 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL156975-03

NOVEL METABOLITE AND MICROBIOTA PATHWAYS FOR HYPERURICEMIA AND GOUT
03/01/2023 - 02/28/2026 (Subcontract PI)
Massachusetts General Hospital NIH NIAMS
5R01AR065944-07

Cardiovascular disease, metabolic syndrome, microbes and metabolites in FHS
02/01/2022 - 01/31/2026 (Subcontract PI)
Broad Institute, Inc., The NIH NHLBI
1R01HL157717-01A1

The San Antonio Heart and Mind Study
07/01/2023 - 03/31/2024 (Subcontract PI)
University of Texas Health Science Center at San Antonio NIH NIA
1R01AG082360-01

Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise Training
08/05/2021 - 06/30/2023 (PI)
NIH/National Heart, Lung, and Blood Institute
7K23HL138260-07



Title


Yr Title Project-Sub Proj Pubs
2023 Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significance 5R01HL156975-03
2023 Proteomic Profiling of Precise Exercise Pathophenotypes Across the HFpEF Spectrum 2R01HL131029-05A1
2022 Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significance 5R01HL156975-02
2021 Metabolic Responses to an Oral Mixed Meal Tolerance Test: Intra-individual changes, correlates, and prognostic significance 1R01HL156975-01
2021 Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise Training 5K23HL138260-06 4
2021 Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise Training 7K23HL138260-07 4
2020 Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise Training 5K23HL138260-05 4
2019 Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise Training 5K23HL138260-04 4
2018 Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise Training 5K23HL138260-03 4
2017 Metabolic Signatures of Impaired Cardiorespiratory Fitness: Correlates, Prognostic Significance and Modulation with Exercise Training 7K23HL138260-02 4

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Hardin KM, Giverts I, Campain J, Farrell R, Cunningham T, Brooks L, Christ A, Wooster L, Bailey CS, Schoenike M, Sbarbaro J, Baggish A, Nayor M, Ho JE, Malhotra R, Shah R, Lewis GD. Systemic Arterial Oxygen Levels Differentiate Pre- and Post-capillary Predominant Hemodynamic Abnormalities During Exercise in Undifferentiated Dyspnea on Exertion. J Card Fail. 2023 Jul 17. PMID: 37467924
     
  2. Nayor M, Lloyd-Jones DM, Shah RV. Introduction to the Compendium on Early Cardiovascular Disease. Circ Res. 2023 Jun 09; 132(12):1567-1569. PMID: 37289907
     
  3. Li Y, Wang M, Liu X, Rong J, Miller PE, Joehanes R, Huan T, Guo X, Rotter J, Smith J, Yu B, Nayor M, Levy D, Liu C, Ma J. Circulating Metabolites May Illustrate Relationship of Alcohol Consumption with Cardiovascular Disease. medRxiv. 2023 May 29. PMID: 37398015; PMCID: PMC10312833; DOI: 10.1101/2023.05.24.23290487;
     
  4. Mi MY, Gajjar P, Walker ME, Miller P, Xanthakis V, Murthy VL, Larson MG, Vasan RS, Shah RV, Lewis GD, Nayor M. Association of healthy dietary patterns and cardiorespiratory fitness in the community. Eur J Prev Cardiol. 2023 Apr 28.View Related Profiles. PMID: 37164358
     
  5. Perry AS, Annis JS, Master H, Nayor M, Hughes A, Kouame A, Natarajan K, Marginean K, Murthy V, Roden DM, Harris PA, Shah R, Brittain EL. Association of Longitudinal Activity Measures and Diabetes Risk: An Analysis From the National Institutes of Health All of Us Research Program. J Clin Endocrinol Metab. 2023 Apr 13; 108(5):1101-1109. PMID: 36458881; PMCID: PMC10306083; DOI: 10.1210/clinem/dgac695;
     
  6. Petek BJ, Churchill TW, Gustus SK, Schoenike MW, Nayor M, Moulson N, Guseh JS, VanAtta C, Blodgett JB, Contursi M, Lewis GD, Baggish AL, Wasfy MM. Characterization of ventilatory efficiency during cardiopulmonary exercise testing in healthy athletes. Eur J Prev Cardiol. 2023 Mar 27; 30(5):e21-e24. PMID: 36321382; PMCID: PMC10290882; DOI: 10.1093/eurjpc/zwac255;
     
  7. Shah RV, Steffen LM, Nayor M, Reis JP, Jacobs DR, Allen NB, Lloyd-Jones D, Meyer K, Cole J, Piaggi P, Vasan RS, Clish CB, Murthy VL. Dietary metabolic signatures and cardiometabolic risk. Eur Heart J. 2023 Feb 14; 44(7):557-569. PMID: 36424694; PMCID: PMC10169425; DOI: 10.1093/eurheartj/ehac446;
     
  8. Mi MY, Gajjar P, Walker ME, Miller P, Xanthakis V, Murthy VL, Larson MG, Vasan RS, Shah RV, Lewis GD, Nayor M. Association of Healthy Dietary Patterns and Cardiorespiratory Fitness in the Community. medRxiv. 2023 Feb 10.View Related Profiles. PMID: 36798343; PMCID: PMC9934801; DOI: 10.1101/2023.02.09.23285714;
     
  9. Nayor M, Gajjar P, Murthy VL, Miller PE, Velagaleti RS, Larson MG, Vasan RS, Lewis GD, Mitchell GF, Shah RV. Blood Pressure Responses During Exercise: Physiological Correlates and Clinical Implications. Arterioscler Thromb Vasc Biol. 2023 Jan; 43(1):163-173.View Related Profiles. PMID: 36384270; PMCID: PMC9780190; DOI: 10.1161/ATVBAHA.122.318512;
     
  10. Perry AS, Tanriverdi K, Risitano A, Hwang SJ, Murthy VL, Nayor M, Zhao S, Levy D, Shah RV, Freedman JE. The inflammatory proteome, obesity, and medical weight loss and regain in humans. Obesity (Silver Spring). 2023 Jan; 31(1):150-158.View Related Profiles. PMID: 36334095; PMCID: PMC9923277; DOI: 10.1002/oby.23587;
     
Showing 10 of 63 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 63 publications over 12 distinct years, with a maximum of 14 publications in 2021

YearPublications
20102
20111
20141
20155
20161
20173
20187
20192
202010
202114
20229
20238

2021 Boston University School of Medicine: Aram Chobanian Assistant Professor of Medicine
2021 Boston University Medical Center: Boston University School of Medicine Department of Medicine Career Development Award
2018-2020 National Institutes of Health: Loan Repayment Program
2016 Brigham and Women's Hospital, Cardiovascular Medicine Division: Richard Gorlin Fellowship in Cardiovascular Medicine
2012 Johns Hopkins Hospital Osler Medical Residency: Frank L. Coulson, Jr. Award for Clinical Excellence
2009 NYU School of Medicine: Clerkship Award for Outstanding Essay in the Philosophy of Medicine
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Epidemiology, Molecular
Exercise, Physical
Metabolomics
Proteomics
Heart Failure, Diastolic
Heart Failure, Systolic
Metabolic Cardiovascular Syndrome

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