Jacob Beierle
Predoctoral Trainee
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Pharmacology, Physiology & Biophysics




Jacob is a Ph.D. graduate student in the Department of Pharmacology. Jacob graduated from the University of Vermont with a B.S. in neuroscience in 2014 and during his time there, researched in the laboratory of Dr. William Falls investigating the relationship between anxiety, exercise, and the HPA axis. After graduation, Jacob became a member of Dr. Shanjana Awasthi’s lab at the University of Oklahoma, investigating the effect of a novel peptide on lung inflammation and bacterial infection. Within the Laboratory of Addiction Genetics, Jacob has taken an interest in genetic factors underlying differences in behavioral responses to opioid use.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Borrelli KN, Wingfield KK, Yao EJ, Zamorano CA, Sena KD, Beierle JA, Roos MA, Zhang H, Wachman EM, Bryant CD. Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice. Neuropharmacology. 2023 Dec 01; 240:109732.View Related Profiles. PMID: 37774943; PMCID: PMC10598517; DOI: 10.1016/j.neuropharm.2023.109732;
     
  2. Borrelli KN, Wingfield KK, Yao EJ, Zamorano CA, Sena KD, Beierle JA, Roos MA, Zhang H, Wachman EM, Bryant CD. Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice. bioRxiv. 2023 Aug 07.View Related Profiles. PMID: 37609129; PMCID: PMC10441327; DOI: 10.1101/2023.08.04.552033;
     
  3. Sena KD, Beierle JA, Richardson KT, Kantak KM, Bryant CD. Assessment of Binge-Like Eating of Unsweetened vs. Sweetened Chow Pellets in BALB/c Substrains. Front Behav Neurosci. 2022; 16:944890.View Related Profiles. PMID: 35910681; PMCID: PMC9337213; DOI: 10.3389/fnbeh.2022.944890;
     
  4. Beierle JA, Yao EJ, Goldstein SI, Lynch WB, Scotellaro JL, Shah AA, Sena KD, Wong AL, Linnertz CL, Averin O, Moody DE, Reilly CA, Peltz G, Emili A, Ferris MT, Bryant CD. Zhx2 Is a Candidate Gene Underlying Oxymorphone Metabolite Brain Concentration Associated with State-Dependent Oxycodone Reward. J Pharmacol Exp Ther. 2022 Aug; 382(2):167-180.View Related Profiles. PMID: 35688478; PMCID: PMC9341249; DOI: 10.1124/jpet.122.001217;
     
  5. Borrelli KN, Wachman EM, Beierle JA, Taglauer ES, Jain M, Bryant CD, Zhang H. Effect of Prenatal Opioid Exposure on the Human Placental Methylome. Biomedicines. 2022 May 17; 10(5).View Related Profiles. PMID: 35625888; PMCID: PMC9138340; DOI: 10.3390/biomedicines10051150;
     
  6. Beierle JA, Yao EJ, Goldstein SI, Scotellaro JL, Sena KD, Linnertz CA, Willits AB, Kader L, Young EE, Peltz G, Emili A, Ferris MT, Bryant CD. Genetic basis of thermal nociceptive sensitivity and brain weight in a BALB/c reduced complexity cross. Mol Pain. 2022 Jan-Dec; 18:17448069221079540.View Related Profiles. PMID: 35088629; PMCID: PMC8891926; DOI: 10.1177/17448069221079540;
     
  7. Goldberg LR, Yao EJ, Kelliher JC, Reed ER, Wu Cox J, Parks C, Kirkpatrick SL, Beierle JA, Chen MM, Johnson WE, Homanics GE, Williams RW, Bryant CD, Mulligan MK. A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity. Genes Brain Behav. 2021 11; 20(8):e12774.View Related Profiles. PMID: 34677900; PMCID: PMC9083095; DOI: 10.1111/gbb.12774;
     
  8. Awasthi S, Kumar G, Ramani V, Awasthi V, Rodgers KK, Xie J, Beierle J, Kyere-Davies G, Singh B, Rahman N, Chowdhury AA, Chataut N. Mechanism of Anti-Inflammatory Activity of TLR4-Interacting SPA4 Peptide. Immunohorizons. 2021 08 24; 5(8):659-674. PMID: 34429343; PMCID: PMC8673433; DOI: 10.4049/immunohorizons.2100067;
     
  9. Wachman EM, Wang A, Isley BC, Boateng J, Beierle JA, Hansbury A, Shrestha H, Bryant C, Zhang H. Placental OPRM1 DNA methylation and associations with neonatal opioid withdrawal syndrome, a pilot study. Explor Med. 2020 Jun; 1(3):124-135.View Related Profiles. PMID: 33763662; PMCID: PMC7985727; DOI: 10.37349/emed.2020.00009;
     
  10. Ruan QT, Yazdani N, Reed ER, Beierle JA, Peterson LP, Luttik KP, Szumlinski KK, Johnson WE, Ash PEA, Wolozin B, Bryant CD. 5' UTR variants in the quantitative trait gene Hnrnph1 support reduced 5' UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity. FASEB J. 2020 07; 34(7):9223-9244.View Related Profiles. PMID: 32401417; PMCID: PMC8006537; DOI: 10.1096/fj.202000092R;
     
Showing 10 of 15 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 15 publications over 7 distinct years, with a maximum of 4 publications in 2022

YearPublications
20131
20181
20192
20203
20212
20224
20232

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