Elizabeth Pearce | Profiles RNS

Elizabeth N. Pearce, MD, MSc

Professor

Boston University Chobanian & Avedisian School of Medicine

Medicine

Endocrinology, Diabetes, Nutrition & Weight Management

MD, Harvard Medical School
MS, Boston University School of Public Health
BA, Harvard College

Websites

Boston Medical Center Provider Profile

ORCID : 0000-0003-3799-0354

Dr. Pearce is a renowned clinical investigator, endocrinologist and epidemiologist who has made significant contributions in iodine nutrition, thyroid disease in pregnancy, environmental thyroid disrupters and the association of thyroid function with cardiovascular risk. Her internationally cited publications have changed recommendations in the US for iodine supplementation and iodine use in pregnancy. A past President of the American Thyroid Association (ATA), Dr. Pearce is the recipient of the prestigious Van Meter Award and she recently co-chaired the ATA’s Thyroid in Pregnancy Guidelines Task Force. She has been part of the leadership of the Iodine Global Network, a nongovernmental agency devoted to the elimination of iodine deficiency disorders, since 2007.

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Combining the datasets of four clinical studies on thyroid endpoints following perchlorate exposure
08/16/2016 - 07/31/2017 (PI)
SQM North America Corporation

Cardiovascular Consequences of Thyroid Dysfunction
09/30/2003 - 06/30/2008 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5 K23 DK64611 05

Rapid Test Kit for Measurement of Urinary Iodine
12/14/2020 - 12/31/2021 (PI)
Lynntech, Inc. National Institutes

Perchiorate and Thyroid Hormones In Pregnancy and Infants in Southern California
06/01/2013 - 05/31/2016 (PI)
Univ of Cailfornia, Berkeley NIH-NIEHS

Title

Yr	Title	Project-Sub Proj	Pubs
2007	EFFECTS OF H2 BLOCKERS, PROTON PUMP INHIBITORS AND EZETIMIBE ON THYROXINE ABSORP	2M01RR000533-39-8177	503
2007	SEQUENTIAL BREAST MILK IODINE CONCENTRATIONS: EFFECT OF SMOKING AND PECHLORATE	2M01RR000533-39-8179	503
2007	Cardiovascular Consequences of Thyroid Dysfunction	5K23DK064611-05	6
2006	Cardiovascular Consequences of Thyroid Dysfunction	5K23DK064611-04	6
2005	Cardiovascular Consequences of Thyroid Dysfunction	5K23DK064611-03	6
2004	Cardiovascular Consequences of Thyroid Dysfunction	5K23DK064611-02	6
2003	Cardiovascular Consequences of Thyroid Dysfunction	1K23DK064611-01	6

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Peng CC, Lee SY, Pearce EN. Isolated Maternal Hypothyroxinemia: Adverse Maternofetal Outcomes but Uncertainty About Treatment Remains. Thyroid. 2023 May; 33(5):535-537. PMID: 36987374

Shan Z, Li Y, Li Y, Wang H, Teng D, Teng X, Chong W, Shi X, Li J, Guo J, Lou Z, Fan C, Ding S, He L, Liu H, Pearce EN, Teng W. Changing iodine status and the incidence of thyroid disease in mainland China: A prospective 20-year follow-up study. Thyroid. 2023 Apr 21. PMID: 37082958

Lee SY, Modzelewski KL, Law AC, Walkey AJ, Pearce EN, Bosch NA. Comparison of Propylthiouracil vs Methimazole for Thyroid Storm in Critically Ill Patients. JAMA Netw Open. 2023 Apr 03; 6(4):e238655.View Related Profiles.

Walkey, Allan
Law, Anica
Pearce, Elizabeth
Modzelewski, Katherine
Bosch, Nicholas

PMID: 37067797; PMCID: PMC10111182; DOI: 10.1001/jamanetworkopen.2023.8655;

Wu W, Guo W, Zhang N, Gao M, Zhang K, Pearce EN, Li S, Ren Z, Yang Y, Wang C, Zhang W. Adverse Effects on the Thyroid of Chinese Pregnant Women Exposed to Long-Term Iodine Excess: Optimal and Safe Tolerable Upper Intake Levels of Iodine. Nutrients. 2023 Mar 28; 15(7). PMID: 37049475; PMCID: PMC10097226; DOI: 10.3390/nu15071635;

Peng C, Lee SY, Pearce EN. Isolated Maternal Hypothyroxinemia: Adverse Maternofetal Outcomes but Uncertainty about Treatment Remains. Thyroid. 2023 Mar 28. PMID: 36987374

Pearce EN, Zimmermann MB. The Prevention of Iodine Deficiency: A History. Thyroid. 2023 Feb; 33(2):143-149. PMID: 36795091

Chen W, Wang W, Gao M, Chen Y, Guo W, Dong S, Sun H, Pan Z, Pearce EN, Tan L, Shen J, Zhang W. Iodine Intakes of <150 µg/day or >550 µg/day are Not Recommended during Pregnancy: A Balance Study. J Nutr. 2022 Dec 22. PMID: 37100687

Shin HM, Oh J, J Schmidt R, N Pearce E. Prenatal Exposure to Per- and Polyfluoroalkyl Substances, Maternal Thyroid Dysfunction, and Child Autism Spectrum Disorder. Endocrinol Metab (Seoul). 2022 Dec; 37(6):819-829. PMID: 36415960; PMCID: PMC9816503; DOI: 10.3803/EnM.2022.1598;

Guo W, Wu W, Gao M, Yang Y, Pearce EN, Li S, Ren Z, Zhang N, Zhang K, Pan Z, Zhang W. Characteristics and predictors of breast milk iodine in exclusively breastfed infants: Results from a repeated-measures study of iodine metabolism. Front Nutr. 2022; 9:1017744. PMID: 36438740; PMCID: PMC9682142; DOI: 10.3389/fnut.2022.1017744;

Croce L, Chiovato L, Tonacchera M, Petrosino E, Tanda ML, Moleti M, Magri F, Olivieri A, Pearce EN, Rotondi M. Iodine status and supplementation in pregnancy: an overview of the evidence provided by meta-analyses. Rev Endocr Metab Disord. 2023 Apr; 24(2):241-250. PMID: 36227457; PMCID: PMC10023614; DOI: 10.1007/s11154-022-09760-7;

Showing 10 of 228 results. Show More

Osinga JAJ, Derakhshan A, Palomaki GE, Ashoor G, Männistö T, Maraka S, Chen L, Bliddal S, Lu X, Taylor PN, Vrijkotte TGM, Tao FB, Brown SJ, Ghafoor F, Poppe K, Veltri F, Chatzi L, Vaidya B, Broeren MAC, Shields BM, Itoh S, Mosso L, Popova PV, Anopova AD, Kishi R, Aminorroaya A, Kianpour M, López-Bermejo A, Oken E, Pirzada A, Vafeiadi M, Bramer WM, Suvanto E, Yoshinaga J, Huang K, Bassols J, Boucai L, Feldt-Rasmussen U, Grineva EN, Pearce EN, Alexander EK, Pop VJM, Nelson SM, Walsh JP, Peeters RP, Chaker L, Nicolaides KH, D'Alton ME, Korevaar TIM. TSH and FT4 Reference Intervals in Pregnancy: A Systematic Review and Individual Participant Data Meta-Analysis. J Clin Endocrinol Metab. 2022 Sep 28; 107(10):2925-2933. PMID: 35861700; PMCID: PMC9516198; DOI: 10.1210/clinem/dgac425;

Peng CC, Maraka S, Pearce EN. Under and overtreatment with thyroid hormone replacement during pregnancy. Curr Opin Endocrinol Diabetes Obes. 2022 Oct 01; 29(5):474-482. PMID: 35855544

Bliddal S, Derakhshan A, Xiao Y, Chen LM, Männistö T, Ashoor G, Tao F, Brown SJ, Vafeiadi M, Itoh S, Grineva EN, Taylor P, Ghafoor F, Vaidya B, Hattersley A, Mosso L, Oken E, Kishi R, Alexander EK, Maraka S, Huang K, Chaker L, Bassols J, Pirzada A, López-Bermejo A, Boucai L, Peeters RP, Pearce EN, Nelson SM, Chatzi L, Vrijkotte TG, Popova PV, Walsh JP, Nicolaides KH, Suvanto E, Lu X, Pop VJM, Forman JL, Korevaar TIM, Feldt-Rasmussen U. Association of Thyroid Peroxidase Antibodies and Thyroglobulin Antibodies with Thyroid Function in Pregnancy: An Individual Participant Data Meta-Analysis. Thyroid. 2022 Jul; 32(7):828-840. PMID: 35596568

Rotondi M, Bendotti G, Croce L, Molteni M, Carbone A, Magri F, Pearce EN, Chiovato L. A unique presentation of Graves' disease in a pregnant woman with severe hypothyroidism. Gynecol Endocrinol. 2022 Aug; 38(8):697-701. PMID: 35723545

Solomon AL, Farwell AP, Pearce EN, Lee SY. Letter to the Editor: A Patient-Centered Survey-Based Assessment of Prenatal Management of Hypothyroidism for Women of Reproductive Age. Thyroid. 2022 Jul; 32(7):871-874.View Related Profiles.

Farwell, Alan
Solomon, Alexandra
Pearce, Elizabeth
Lee, Sun

PMID: 35596561; PMCID: PMC9293681; DOI: 10.1089/thy.2022.0032;

Chaker L, Razvi S, Bensenor IM, Azizi F, Pearce EN, Peeters RP. Publisher Correction: Hypothyroidism. Nat Rev Dis Primers. 2022 Jun 10; 8(1):39. PMID: 35688906

Nazeri P, Akbarzadeh M, Pearce EN, Hedayati M, Dalili H. Iodine Status of Preterm Infants Born in an Area of Iodine Sufficiency: Are They at Risk of Iodine Deficiency? Endocr Pract. 2022 Sep; 28(9):835-841. PMID: 35671879

Chaker L, Razvi S, Bensenor IM, Azizi F, Pearce EN, Peeters RP. Hypothyroidism. Nat Rev Dis Primers. 2022 May 19; 8(1):30. PMID: 35589725

Pearce EN. Management of Hypothyroidism and Hypothyroxinemia During Pregnancy. Endocr Pract. 2022 Jul; 28(7):711-718. PMID: 35569735

Toloza FJK, Derakhshan A, Männistö T, Bliddal S, Popova PV, Carty DM, Chen L, Taylor P, Mosso L, Oken E, Suvanto E, Itoh S, Kishi R, Bassols J, Auvinen J, López-Bermejo A, Brown SJ, Boucai L, Hisada A, Yoshinaga J, Shilova E, Grineva EN, Vrijkotte TGM, Sunyer J, Jiménez-Zabala A, Riaño-Galan I, Lopez-Espinosa MJ, Prokop LJ, Singh Ospina N, Brito JP, Rodriguez-Gutierrez R, Alexander EK, Chaker L, Pearce EN, Peeters RP, Feldt-Rasmussen U, Guxens M, Chatzi L, Delles C, Roeters van Lennep JE, Pop VJM, Lu X, Walsh JP, Nelson SM, Korevaar TIM, Maraka S. Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis. Lancet Diabetes Endocrinol. 2022 04; 10(4):243-252. PMID: 35255260

Pearce EN, Korevaar TIM, Leung AM. Levothyroxine for the Treatment of Subclinical Hypothyroidism in Thyroperoxidase Antibody Negative Pregnant Women: The Jury Is Still Out. Thyroid. 2022 Apr; 32(4):349-350. PMID: 35107366

Peng CC, Pearce EN. An update on thyroid disorders in the postpartum period. J Endocrinol Invest. 2022 Aug; 45(8):1497-1506. PMID: 35181848

Lee SY, Pearce EN. Assessment and treatment of thyroid disorders in pregnancy and the postpartum period. Nat Rev Endocrinol. 2022 03; 18(3):158-171.View Related Profiles.

Pearce, Elizabeth
Lee, Sun

PMID: 34983968; PMCID: PMC9020832; DOI: 10.1038/s41574-021-00604-z;

Lee SY, Pearce EN. Preconception Care to Optimize Pregnancy Outcomes. JAMA. 2021 12 07; 326(21):2204-2205.View Related Profiles.

Pearce, Elizabeth
Lee, Sun

PMID: 34874428; PMCID: PMC9036834; DOI: 10.1001/jama.2021.16759;

Chen Y, Guo W, Pan Z, Zhang D, Gao M, Wu W, Wang C, Duan Y, Gu X, Pearce EN, Lai J, Zhang W. Exploration of the optimal range of urinary iodine concentration in Chinese pregnant women in mildly iodine-deficient and -sufficient areas. Eur J Nutr. 2022 Apr; 61(3):1221-1230. PMID: 34739565

Amouzegar A, Pearce EN, Mehran L, Lazarus J, Takyar M, Azizi F. TPO antibody in euthyroid pregnant women and cognitive ability in the offspring: a focused review. J Endocrinol Invest. 2022 Feb; 45(2):425-431. PMID: 34515961

Nazeri P, Tahmasebinejad Z, Pearce EN, Zarezadeh Z, Tajeddini T, Mirmiran P, Azizi F. Does maternal iodine supplementation during the lactation have a positive impact on neurodevelopment of children? Three-year follow up of a randomized controlled trial. Eur J Nutr. 2021 Oct; 60(7):4083-4091. PMID: 33974129

Siskind SM, Lee SY, Pearce EN. Investigating hypothyroidism. BMJ. 2021 04 27; 373:n993.View Related Profiles.

Pearce, Elizabeth
Siskind, Samantha

PMID: 33906834

Sekhon I, Pearce EN, He X, Lee SY. Iodine Content in Meal Replacements in the United States. Endocr Pract. 2021 Jul; 27(7):668-672.View Related Profiles.

Pearce, Elizabeth
Lee, Sun

PMID: 33705969; PMCID: PMC9009516; DOI: 10.1016/j.eprac.2021.03.002;

Lee SY, Pearce EN. Testing, Monitoring, and Treatment of Thyroid Dysfunction in Pregnancy. J Clin Endocrinol Metab. 2021 03 08; 106(3):883-892.View Related Profiles.

Pearce, Elizabeth
Lee, Sun

PMID: 33349844; PMCID: PMC7947825; DOI: 10.1210/clinem/dgaa945;

Guo W, Dong S, Jin Y, Pan Z, Pearce EN, Wu W, Zhang Y, Chen W, Zhang W. Evaluation of variation of saliva iodine and recommendations for sample size and sampling time: Implications for assessing iodine nutritional status. Clin Nutr. 2021 05; 40(5):3559-3566. PMID: 33388206

Rodriguez-Diaz E, Rivera-Ortiz JI, Lee SY, Gonzalez-Rodriguez LA, He X, Pearce EN. Iodine Status in Pregnant Women of Puerto Rico. Endocr Pract. 2021 Mar; 27(3):241-244.View Related Profiles.

Pearce, Elizabeth
Lee, Sun

PMID: 33618848; PMCID: PMC9009515; DOI: 10.1016/j.eprac.2020.10.002;

Kerver JM, Pearce EN, Elliott MR, Paneth N. Clearing up the misinterpretation on iodine intake in pregnancy. Am J Obstet Gynecol. 2021 04; 224(4):418-419. PMID: 33221295

Pearce EN. An endocrinologist's journey in iodine nutrition. Eur J Clin Nutr. 2022 01; 76(1):1-4. PMID: 33199852

Sawka AM, Alexander EK, Bianco AC, Chou R, Haugen BR, Kopp PA, Pearce EN, Ross DS, Smallridge RC, Jonklaas J. Challenges in Developing Recommendations Based on Low-Quality Evidence in Thyroid Guidelines. Thyroid. 2021 01; 31(1):3-7. PMID: 32900277

Nazeri P, Shab-Bidar S, Pearce EN, Shariat M. Do maternal urinary iodine concentration or thyroid hormones within the normal range during pregnancy affect growth parameters at birth? A systematic review and meta-analysis. Nutr Rev. 2020 09 01; 78(9):747-763. PMID: 31923312

Singer MC, Marchal F, Angelos P, Bernet V, Boucai L, Buchholzer S, Burkey B, Eisele D, Erkul E, Faure F, Freitag SK, Gillespie MB, Harrell RM, Hartl D, Haymart M, Leffert J, Mandel S, Miller BS, Morris J, Pearce EN, Rahmati R, Ryan WR, Schaitkin B, Schlumberger M, Stack BC, Van Nostrand D, Wong KK, Randolph G. Salivary and lacrimal dysfunction after radioactive iodine for differentiated thyroid cancer: American Head and Neck Society Endocrine Surgery Section and Salivary Gland Section joint multidisciplinary clinical consensus statement of otolaryngology, ophthalmology, nuclear medicine and endocrinology. Head Neck. 2020 11; 42(11):3446-3459. PMID: 32812307

Gorstein JL, Bagriansky J, Pearce EN, Kupka R, Zimmermann MB. Estimating the Health and Economic Benefits of Universal Salt Iodization Programs to Correct Iodine Deficiency Disorders. Thyroid. 2020 12; 30(12):1802-1809. PMID: 32458745; PMCID: PMC7757618; DOI: 10.1089/thy.2019.0719;

Kerver JM, Pearce EN, Ma T, Gentchev M, Elliott MR, Paneth N. Prevalence of inadequate and excessive iodine intake in a US pregnancy cohort. Am J Obstet Gynecol. 2021 01; 224(1):82.e1-82.e8. PMID: 32653458; PMCID: PMC7779669; DOI: 10.1016/j.ajog.2020.06.052;

Pearce EN. Thyroid Autoimmunity Is Associated With Postpartum Thyroiditis Risk, Even in Women With Treated Hypothyroidism. J Clin Endocrinol Metab. 2020 07 01; 105(7). PMID: 32422650

Rodriguez-Diaz E, Pearce EN. Iodine status and supplementation before, during, and after pregnancy. Best Pract Res Clin Endocrinol Metab. 2020 07; 34(4):101430. PMID: 32792134

Pinardo H, Rubin SJ, Hashemi S, DePietro J, Pearce EN, Ananthakrishnan S, Alexanian SM, Steenkamp DW, Noordzij JP. The use of vitamin D in preventing post-thyroidectomy hypocalcemia: An endocrinologist survey study. Clin Endocrinol (Oxf). 2020 11; 93(5):598-604.View Related Profiles.

Steenkamp, Devin
Pearce, Elizabeth
Noordzij, J.
Rubin, Samuel
Alexanian, Sara
Ananthakrishnan, Sonia

PMID: 32469425

Derakhshan A, Peeters RP, Taylor PN, Bliddal S, Carty DM, Meems M, Vaidya B, Chen L, Knight BA, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan CM, French R, Boucai L, Vafeiadi M, Grineva EN, Pop VJM, Vrijkotte TG, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Rebagliato M, Lu X, Pirzada A, Männistö T, Delles C, Feldt-Rasmussen U, Alexander EK, Nelson SM, Chaker L, Pearce EN, Guxens M, Steegers EAP, Walsh JP, Korevaar TIM. Association of maternal thyroid function with birthweight: a systematic review and individual-participant data meta-analysis. Lancet Diabetes Endocrinol. 2020 06; 8(6):501-510. PMID: 32445737; PMCID: PMC8168324; DOI: 10.1016/S2213-8587(20)30061-9;

Lee SY, Cabral HJ, Aschengrau A, Pearce EN. Associations Between Maternal Thyroid Function in Pregnancy and Obstetric and Perinatal Outcomes. J Clin Endocrinol Metab. 2020 05 01; 105(5).View Related Profiles.

Aschengrau, Ann
Pearce, Elizabeth
Cabral, Howard
Lee, Sun

PMID: 31838502; PMCID: PMC7089848; DOI: 10.1210/clinem/dgz275;

Rubin SJ, Park JH, Pearce EN, Holick MF, McAneny D, Noordzij JP. Vitamin D Status as a Predictor of Postoperative Hypocalcemia after Thyroidectomy. Otolaryngol Head Neck Surg. 2020 Sep; 163(3):501-507.View Related Profiles.

McAneny, David
Pearce, Elizabeth
Noordzij, J.
Holick, Michael
Rubin, Samuel

PMID: 32312160

Preston EV, Webster TF, Claus Henn B, McClean MD, Gennings C, Oken E, Rifas-Shiman SL, Pearce EN, Calafat AM, Fleisch AF, Sagiv SK. Prenatal exposure to per- and polyfluoroalkyl substances and maternal and neonatal thyroid function in the Project Viva Cohort: A mixtures approach. Environ Int. 2020 06; 139:105728.View Related Profiles.

Claus Henn, Birgit
Pearce, Elizabeth
McClean, Michael
Webster, Thomas

PMID: 32311629; PMCID: PMC7282386; DOI: 10.1016/j.envint.2020.105728;

Lain SJ, Rifas-Shiman SL, Pearce EN, Nassar N, Oken E. Neonatal Thyroxine, Maternal Thyroid Function, and Cognition in Mid-childhood in a US Cohort. Matern Child Health J. 2020 Apr; 24(4):503-513. PMID: 31897929; PMCID: PMC7083173; DOI: 10.1007/s10995-019-02867-5;

Nazeri P, Shab-Bidar S, Pearce EN, Shariat M. Thyroglobulin Concentration and Maternal Iodine Status During Pregnancy: A Systematic Review and Meta-Analysis. Thyroid. 2020 05; 30(5):767-779. PMID: 31910106

Korevaar TIM, Derakhshan A, Taylor PN, Meima M, Chen L, Bliddal S, Carty DM, Meems M, Vaidya B, Shields B, Ghafoor F, Popova PV, Mosso L, Oken E, Suvanto E, Hisada A, Yoshinaga J, Brown SJ, Bassols J, Auvinen J, Bramer WM, López-Bermejo A, Dayan C, Boucai L, Vafeiadi M, Grineva EN, Tkachuck AS, Pop VJM, Vrijkotte TG, Guxens M, Chatzi L, Sunyer J, Jiménez-Zabala A, Riaño I, Murcia M, Lu X, Mukhtar S, Delles C, Feldt-Rasmussen U, Nelson SM, Alexander EK, Chaker L, Männistö T, Walsh JP, Pearce EN, Steegers EAP, Peeters RP. Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis. JAMA. 2019 08 20; 322(7):632-641. PMID: 31429897; PMCID: PMC6704759; DOI: 10.1001/jama.2019.10931;

Feldt-Rasmussen U, Emerson CH, Ross DS, Kopp PA, Pearce EN. Thoughts on the Japanese and American Perspectives on Thyroid Storm. Thyroid. 2019 08; 29(8):1033-1035. PMID: 31140377

Cui T, Wang W, Chen W, Pan Z, Gao S, Tan L, Pearce EN, Zimmermann MB, Shen J, Zhang W. Serum Iodine Is Correlated with Iodine Intake and Thyroid Function in School-Age Children from a Sufficient-to-Excessive Iodine Intake Area. J Nutr. 2019 06 01; 149(6):1012-1018. PMID: 31070733

Chittimoju SB, Pearce EN. Iodine Deficiency and Supplementation in Pregnancy. Clin Obstet Gynecol. 2019 06; 62(2):330-338. PMID: 30829881

Fallah R, Du L, Braverman LE, He X, Segura-Harrison M, Yeh MW, Pearce EN, Chiu HK, Mittelman SD, Leung AM. Iodine Nutrition in Weaning Infants in the United States. Thyroid. 2019 04; 29(4):573-576.View Related Profiles.

Year	Publications
2001	1
2002	2
2003	4
2004	8
2005	6
2006	7
2007	9
2008	10
2009	5
2010	12
2011	16
2012	16
2013	15
2014	16
2015	12
2016	7
2017	14
2018	12
2019	8
2020	18
2021	7
2022	17
2023	5