Keywords
Last Name

Alan P. Farwell, MD

TitleAssociate Professor
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionEndocrinology, Diabetes & Nutrition
Address88 E. Newton St Newton Pavilion
Boston MA 02118
Phone(617) 638-8873
ORCID ORCID Icon0000-0001-7716-2719
Other Positions
TitleSection Chief of Medicine in Endocrinology, Diabetes & Nutrition
InstitutionBoston University School of Medicine
DepartmentMedicine
DivisionEndocrinology, Diabetes & Nutrition

 Research Expertise & Professional Interests
Expertise includes: Manuscript preparation and review - serve as an EIC and on editorial boards; Leadership and managing teams - currently clinic director; also completed Pocket MBA in 2010.

 Self-Described Keywords
  • Endocrine
  • Thyroid
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Palermo NE, Modzelewski KL, Farwell AP, Fosbroke J, Shankar KN, Alexanian SM, Baker WE, Simonson DC, McDonnell ME. OPEN ACCESS TO DIABETES CENTER FROM THE EMERGENCY DEPARTMENT REDUCES HOSPITALIZATIONS IN THE SUSEQUENT YEAR. Endocr Pract. 2016 Oct; 22(10):1161-1169. PMID: 27732094.
    View in: PubMed
  2. Lee S, Farwell AP. Euthyroid Sick Syndrome. Compr Physiol. 2016 Mar 15; 6(2):1071-80. PMID: 27065175.
    View in: PubMed
  3. Farwell AP. Nonthyroidal illness syndrome. Curr Opin Endocrinol Diabetes Obes. 2013 Oct; 20(5):478-84. PMID: 23974778.
    View in: PubMed
  4. Spitzer M, Alexanian S, Farwell AP. Thyrotoxicosis with post-treatment hypothyroidism in a patient with acute suppurative thyroiditis due to porphyromonas. Thyroid. 2012 Jan; 22(1):97-100. PMID: 22136210.
    View in: PubMed
  5. Farwell AP, Lawrence JE, Pearce EN, Emerson CH, Tangpricha V. E. Chester Ridgway delivers the first Lewis E. Braverman distinguished award lectureship at the American Thyroid Association's 2011 annual meeting. Thyroid. 2011 Dec; 21(12):1293-4. PMID: 22136264.
    View in: PubMed
  6. Farwell AP, Leonard JL. Effect of methyl iodide on deiodinase activity. Inhal Toxicol. 2009 May; 21(6):497-504. PMID: 19519149.
    View in: PubMed
  7. Farwell AP. Thyroid hormone therapy is not indicated in the majority of patients with the sick euthyroid syndrome. Endocr Pract. 2008 Dec; 14(9):1180-7. PMID: 19158057.
    View in: PubMed
  8. Leung AM, Farwell AP. Unsatisfactory consequences from fine-needle aspiration biopsy of thyroid nodules. Thyroid. 2008 May; 18(5):491-2. PMID: 18426364.
    View in: PubMed
  9. Farwell AP, Dubord-Tomasetti SA, Pietrzykowski AZ, Leonard JL. Dynamic nongenomic actions of thyroid hormone in the developing rat brain. Endocrinology. 2006 May; 147(5):2567-74. PMID: 16469804.
    View in: PubMed
  10. Farwell AP, Dubord-Tomasetti SA, Pietrzykowski AZ, Stachelek SJ, Leonard JL. Regulation of cerebellar neuronal migration and neurite outgrowth by thyroxine and 3,3',5'-triiodothyronine. Brain Res Dev Brain Res. 2005 Jan 1; 154(1):121-35. PMID: 15617761.
    View in: PubMed
  11. Pearce EN, Farwell AP, Braverman LE. Thyroiditis. N Engl J Med. 2003 Jun 26; 348(26):2646-55. PMID: 12826640.
    View in: PubMed
  12. Stachelek SJ, Tuft RA, Lifschitz LM, Leonard DM, Farwell AP, Leonard JL. Real-time visualization of processive myosin 5a-mediated vesicle movement in living astrocytes. J Biol Chem. 2001 Sep 21; 276(38):35652-9. PMID: 11470781.
    View in: PubMed
  13. Vacanti MP, Leonard JL, Dore B, Bonassar LJ, Cao Y, Stachelek SJ, Vacanti JP, O'Connell F, Yu CS, Farwell AP, Vacanti CA. Tissue-engineered spinal cord. Transplant Proc. 2001 Feb-Mar; 33(1-2):592-8. PMID: 11266974.
    View in: PubMed
  14. Stachelek SJ, Kowalik TF, Farwell AP, Leonard JL. Myosin V plays an essential role in the thyroid hormone-dependent endocytosis of type II iodothyronine 5'-deiodinase. J Biol Chem. 2000 Oct 13; 275(41):31701-7. PMID: 10882730.
    View in: PubMed
  15. Leonard DM, Stachelek SJ, Safran M, Farwell AP, Kowalik TF, Leonard JL. Cloning, expression, and functional characterization of the substrate binding subunit of rat type II iodothyronine 5'-deiodinase. J Biol Chem. 2000 Aug 18; 275(33):25194-201. PMID: 10829019.
    View in: PubMed
  16. Farwell AP, Dubord-Tomasetti SA. Thyroid hormone regulates the extracellular organization of laminin on astrocytes. Endocrinology. 1999 Nov; 140(11):5014-21. PMID: 10537126.
    View in: PubMed
  17. Farwell AP, Dubord-Tomasetti SA. Thyroid hormone regulates the expression of laminin in the developing rat cerebellum. Endocrinology. 1999 Sep; 140(9):4221-7. PMID: 10465295.
    View in: PubMed
  18. Leonard JL, Leonard DM, Safran M, Wu R, Zapp ML, Farwell AP. The mammalian homolog of the frog type II selenodeiodinase does not encode a functional enzyme in the rat. Endocrinology. 1999 May; 140(5):2206-15. PMID: 10218973.
    View in: PubMed
  19. Leonard JL, Farwell AP. Thyroid hormone-regulated actin polymerization in brain. Thyroid. 1997 Feb; 7(1):147-51. PMID: 9086583.
    View in: PubMed
  20. Farwell AP, Braverman LE. Inflammatory thyroid disorders. Otolaryngol Clin North Am. 1996 Aug; 29(4):541-56. PMID: 8844729.
    View in: PubMed
  21. Farwell AP, Safran M, Dubord S, Leonard JL. Degradation and recycling of the substrate-binding subunit of type II iodothyronine 5'-deiodinase in astrocytes. J Biol Chem. 1996 Jul 5; 271(27):16369-74. PMID: 8663170.
    View in: PubMed
  22. Safran M, Farwell AP, Leonard JL. Catalytic activity of type II iodothyronine 5'-deiodinase polypeptide is dependent upon a cyclic AMP activation factor. J Biol Chem. 1996 Jul 5; 271(27):16363-8. PMID: 8663169.
    View in: PubMed
  23. Leonard JL, Leonard DM, Shen Q, Farwell AP, Newburger PE. Selenium-regulated translation control of heterologous gene expression: normal function of selenocysteine-substituted gene products. J Cell Biochem. 1996 Jun 1; 61(3):410-9. PMID: 8761945.
    View in: PubMed
  24. Farwell AP, Tranter MP, Leonard JL. Thyroxine-dependent regulation of integrin-laminin interactions in astrocytes. Endocrinology. 1995 Sep; 136(9):3909-15. PMID: 7649099.
    View in: PubMed
  25. Leonard JL, Farwell AP, Yen PM, Chin WW, Stula M. Differential expression of thyroid hormone receptor isoforms in neurons and astroglial cells. Endocrinology. 1994 Aug; 135(2):548-55. PMID: 8033801.
    View in: PubMed
  26. Safran M, Farwell AP, Rokos H, Leonard JL. Structural requirements of iodothyronines for the rapid inactivation and internalization of type II iodothyronine 5'-deiodinase in glial cells. J Biol Chem. 1993 Jul 5; 268(19):14224-9. PMID: 8390985.
    View in: PubMed
  27. Chanoine JP, Braverman LE, Farwell AP, Safran M, Alex S, Dubord S, Leonard JL. The thyroid gland is a major source of circulating T3 in the rat. J Clin Invest. 1993 Jun; 91(6):2709-13. PMID: 8514878.
    View in: PubMed
  28. Farwell AP, DiBenedetto DJ, Leonard JL. Thyroxine targets different pathways of internalization of type II iodothyronine 5'-deiodinase in astrocytes. J Biol Chem. 1993 Mar 5; 268(7):5055-62. PMID: 8444882.
    View in: PubMed
  29. Safran M, Farwell AP, Leonard JL. Thyroid hormone-dependent redistribution of the 55-kilodalton monomer of protein disulfide isomerase in cultured glial cells. Endocrinology. 1992 Nov; 131(5):2413-8. PMID: 1425439.
    View in: PubMed
  30. Chanoine JP, Safran M, Farwell AP, Dubord S, Alex S, Stone S, Arthur JR, Braverman LE, Leonard JL. Effects of selenium deficiency on thyroid hormone economy in rats. Endocrinology. 1992 Oct; 131(4):1787-92. PMID: 1396324.
    View in: PubMed
  31. Farwell AP, Leonard JL. Dissociation of actin polymerization and enzyme inactivation in the hormonal regulation of type II iodothyronine 5'-deiodinase activity in astrocytes. Endocrinology. 1992 Aug; 131(2):721-8. PMID: 1322280.
    View in: PubMed
  32. Chanoine JP, Safran M, Farwell AP, Tranter P, Ekenbarger DM, Dubord S, Alex S, Arthur JR, Beckett GJ, Braverman LE, et al. Selenium deficiency and type II 5'-deiodinase regulation in the euthyroid and hypothyroid rat: evidence of a direct effect of thyroxine. Endocrinology. 1992 Jul; 131(1):479-84. PMID: 1612029.
    View in: PubMed
  33. Safran M, Farwell AP, Leonard JL. Evidence that type II 5'-deiodinase is not a selenoprotein. J Biol Chem. 1991 Jul 25; 266(21):13477-80. PMID: 1856186.
    View in: PubMed
  34. Leonard JL, Ekenbarger DM, Frank SJ, Farwell AP, Koehrle J. Localization of type I iodothyronine 5'-deiodinase to the basolateral plasma membrane in renal cortical epithelial cells. J Biol Chem. 1991 Jun 15; 266(17):11262-9. PMID: 2040632.
    View in: PubMed
  35. Farwell AP, Lynch RM, Okulicz WC, Comi AM, Leonard JL. The actin cytoskeleton mediates the hormonally regulated translocation of type II iodothyronine 5'-deiodinase in astrocytes. J Biol Chem. 1990 Oct 25; 265(30):18546-53. PMID: 2170415.
    View in: PubMed
  36. Farwell AP, Abend SL, Huang SK, Patwardhan NA, Braverman LE. Thyroidectomy for amiodarone-induced thyrotoxicosis. JAMA. 1990 Mar 16; 263(11):1526-8. PMID: 2308184.
    View in: PubMed
  37. Farwell AP, Leonard JL. Identification of a 27-kDa protein with the properties of type II iodothyronine 5'-deiodinase in dibutyryl cyclic AMP-stimulated glial cells. J Biol Chem. 1989 Dec 5; 264(34):20561-7. PMID: 2555364.
    View in: PubMed
  38. Evans RW, Farwell AP, Braverman LE. Nuclear thyroid hormone receptor in the rat uterus. Endocrinology. 1983 Oct; 113(4):1459-63. PMID: 6311523.
    View in: PubMed
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