David A. Boas, PhD
Professor
Boston University College of Engineering
Dept of Biomedical Engineering

PhD, University of Pennsylvania




David Boas, Ph.D. (Professor, Biomedical Engineering) is Director of the Neurophotonics Center at Boston University. He received his BS in Physics at Rensselear Polytechnic Institute and PhD in Physics at the University of Pennsylvania. During his academic career, he has supervised 44 students and post-doctoral fellows, and he has published over 250 papers that have received over 30,000 citations and an h-index of 101. He is the founding President of the Society for Functional Near Infrared Spectroscopy and founding Editor-in-Chief of the journal Neurophotonics published by SPIE. Dr. Boas was awarded the Britton Chance Award in Biomedical Optics in 2016 for his development of several novel, high-impact biomedical optical technologies in the neurosciences, as well as following through with impactful application studies, and fostering the widespread adoption of these technologies. He was elected a Fellow of AIMBE, SPIE, and OSA in 2017.

As Director of the Neurophotonics Center, he facilitates the development and application of novel optical methods to address a broad range of neuroscience questions from basic science to clinical translation. His own research efforts focus on neurovascular coupling, cerebral oxygen delivery and consumption, functional near infrared spectroscopy (fNIRS), and physiological modeling. Studies are done in rodents and humans, invasively and non-invasively, microscopically and macroscopically, providing a powerful ability to translate findings from animals to humans, and conversely to address in animals questions raised during human studies. One example of this that will tie together many of Dr. Boas’ activities is studying functional brain recovery in survivors of stroke. Human neuroimaging by fMRI and fNIRS measures hemodynamic functional recovery but it is not known if neuro-vascular coupling differs in these patients compared to healthy subjects. Animal studies will answer this question enabling more quantitative interpretation of the human neuroimaging studies.

Director
Neurophotonics Center




The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function
09/22/2020 - 05/31/2025 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
1U01EB029856-01

Time-Gated Diffuse Correlation Spectroscopy for functional imaging of the human brain
09/21/2019 - 06/30/2024 (Subcontract PI)
Massachusetts General Hospital NIH NIBIB
5U01EB028660-02

The impact of microvascular (dys)regulation on cerebral flow and oxygen heterogeneity
09/01/2018 - 05/31/2023 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS108472-03

Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain
08/22/2018 - 05/31/2023 (Subcontract PI)
Massachusetts General Hospital NIH NIMH
5U01MH117023-03

A Computational Miniature Mesoscope for Large-Scale Brain Mapping in Behaving Mice
04/01/2019 - 03/31/2022 (Multi-PI)
PI: David A. Boas, PhD
NIH/National Eye Institute
1R21EY030016-01

Comparing laser speckle contract and diffuse correlation spectroscopy measurements in human brain function
04/20/2021 - 02/01/2022 (PI)
Facebook Technologies, LLC


Establishing an fNIRS Ecosystem for Open Software-Hardware Dissemination
01/01/2018 - 12/31/2021 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R24NS104096-04

NRT UtB: Neurophotonics
09/01/2016 - 08/31/2021 (Multi-PI)
PI: David A. Boas, PhD
National Science Foundation
DGE-1633516

Improving human FMRI through modeling and imaging microvascular dynamics
11/01/2017 - 07/31/2021 (Subcontract PI)
Massachusetts General Hospital NIH NIMH
5R01MH111419-05

Gated Diffuse Correlation Spectroscopy for functional imaging of the human brain
09/25/2017 - 07/31/2021 (Subcontract PI)
General Hospital Corp d/b/a Massachusetts General Hospital NIH NIBIB
5R01EB025145-02

Showing 10 of 18 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2021 The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function 5U01EB029856-02
2021 The impact of microvascular (dys)regulation on cerebral flow and oxygen heterogeneity 5R01NS108472-04 4
2021 Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain 5U01MH117023-04 5
2021 Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain Admin Supplement 3U01MH117023-04S1 5
2021 Establishing an fNIRS Ecosystem for Open Software-Hardware Dissemination 5R24NS104096-04 1
2020 The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function 1U01EB029856-01
2020 The impact of microvascular (dys)regulation on cerebral flow and oxygen heterogeneity 5R01NS108472-03 4
2020 Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain 5U01MH117023-03 5
2020 Establishing an fNIRS Ecosystem for Open Software-Hardware Dissemination 5R24NS104096-03 1
2019 A Computational Miniature Mesoscope for Large-Scale Brain Mapping in Behaving Mice 1R21EY030016-01
Showing 10 of 100 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Cheng X, Sie EJ, Naufel S, Boas DA, Marsili F. Measuring neuronal activity with diffuse correlation spectroscopy: a theoretical investigation. Neurophotonics. 2021 Jul; 8(3):035004. PMID: 34368390; PMCID: PMC8339443; DOI: 10.1117/1.NPh.8.3.035004;
     
  2. Aykan SA, Xie H, Lai JH, Zheng Y, Chung DY, Kura S, Anzabi M, Sugimoto K, McAllister LM, Yaseen MA, Boas DA, Whalen MJ, Sakadzic S, Ayata C. Focal Subcortical White Matter Lesions Disrupt Resting State Cortical Interhemispheric Functional Connectivity in Mice. Cereb Cortex. 2021 May 25. PMID: 34037216
     
  3. Liu C, Kiliç K, Erdener SE, Boas DA, Postnov DD. Choosing a model for laser speckle contrast imaging. Biomed Opt Express. 2021 Jun 01; 12(6):3571-3583. PMID: 34221679; PMCID: PMC8221943; DOI: 10.1364/BOE.426521;
     
  4. Hartung G, Badr S, Mihelic S, Dunn A, Cheng X, Kura S, Boas DA, Kleinfeld D, Alaraj A, Linninger AA. Mathematical synthesis of the cortical circulation for the whole mouse brain-part II: Microcirculatory closure. Microcirculation. 2021 07; 28(5):e12687. PMID: 33615601
     
  5. Tang J, Cheng X, Kilic K, Devor A, Lee J, Boas DA. Imaging localized fast optical signals of neural activation with optical coherence tomography in awake mice. Opt Lett. 2021 Apr 01; 46(7):1744-1747. PMID: 33793533; PMCID: PMC8086197; DOI: 10.1364/OL.411897;
     
  6. Shao W, Kilic K, Yin W, Wirak G, Qin X, Feng H, Boas D, Gabel CV, Yi J. Wide field-of-view volumetric imaging by a mesoscopic scanning oblique plane microscopy with switchable objective lenses. Quant Imaging Med Surg. 2021 Mar; 11(3):983-997.View Related Profiles. PMID: 33654671; PMCID: PMC7829172; DOI: 10.21037/qims-20-806;
     
  7. Anzabi M, Li B, Wang H, Kura S, Sakadžic S, Boas D, Østergaard L, Ayata C. Optical coherence tomography of arteriolar diameter and capillary perfusion during spreading depolarizations. J Cereb Blood Flow Metab. 2021 Sep; 41(9):2256-2263. PMID: 33593116; PMCID: PMC8393288; DOI: 10.1177/0271678X21994013;
     
  8. Cheng X, Sie EJ, Boas DA, Marsili F. Choosing an optimal wavelength to detect brain activity in functional near-infrared spectroscopy. Opt Lett. 2021 Feb 15; 46(4):924-927. PMID: 33577549
     
  9. Mächler P, Broggini T, Mateo C, Thunemann M, Fomin-Thunemann N, Doran PR, Sencan I, Kilic K, Desjardins M, Uhlirova H, Yaseen MA, Boas DA, Linninger AA, Vergassola M, Yu X, Lewis LD, Polimeni JR, Rosen BR, Sakadžic S, Buxton RB, Lauritzen M, Kleinfeld D, Devor A. A Suite of Neurophotonic Tools to Underpin the Contribution of Internal Brain States in fMRI. Curr Opin Biomed Eng. 2021 Jun; 18. PMID: 33959688; PMCID: PMC8095678; DOI: 10.1016/j.cobme.2021.100273;
     
  10. Yücel MA, Lühmann AV, Scholkmann F, Gervain J, Dan I, Ayaz H, Boas D, Cooper RJ, Culver J, Elwell CE, Eggebrecht A, Franceschini MA, Grova C, Homae F, Lesage F, Obrig H, Tachtsidis I, Tak S, Tong Y, Torricelli A, Wabnitz H, Wolf M. Errata: Best practices for fNIRS publications. Neurophotonics. 2021 Jan; 8(1):019802. PMID: 33575435; PMCID: PMC7868645; DOI: 10.1117/1.NPh.8.1.019802;
     
Showing 10 of 332 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 332 publications over 28 distinct years, with a maximum of 23 publications in 2009

YearPublications
19941
19952
19962
19974
19983
19992
20005
20014
20026
200314
20048
200519
200610
200711
200820
200923
201019
201116
201211
201317
201412
201517
201622
201721
201815
201913
202021
202114
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