David A. Boas, PhD
Professor
Boston University College of Engineering
Biomedical Engineering

PhD, University of Pennsylvania
BS, Rensselaer Polytechnic Institute



David Boas, Ph.D. (Professor, Biomedical Engineering) is Director of the Neurophotonics Center at Boston University. He received his BS in Physics at Rensselear Polytechnic Institute and PhD in Physics at the University of Pennsylvania. During his academic career, he has supervised 44 students and post-doctoral fellows, and he has published over 250 papers that have received over 30,000 citations and an h-index of 101. He is the founding President of the Society for Functional Near Infrared Spectroscopy and founding Editor-in-Chief of the journal Neurophotonics published by SPIE. Dr. Boas was awarded the Britton Chance Award in Biomedical Optics in 2016 for his development of several novel, high-impact biomedical optical technologies in the neurosciences, as well as following through with impactful application studies, and fostering the widespread adoption of these technologies. He was elected a Fellow of AIMBE, SPIE, and OSA in 2017.

As Director of the Neurophotonics Center, he facilitates the development and application of novel optical methods to address a broad range of neuroscience questions from basic science to clinical translation. His own research efforts focus on neurovascular coupling, cerebral oxygen delivery and consumption, functional near infrared spectroscopy (fNIRS), and physiological modeling. Studies are done in rodents and humans, invasively and non-invasively, microscopically and macroscopically, providing a powerful ability to translate findings from animals to humans, and conversely to address in animals questions raised during human studies. One example of this that will tie together many of Dr. Boas’ activities is studying functional brain recovery in survivors of stroke. Human neuroimaging by fMRI and fNIRS measures hemodynamic functional recovery but it is not known if neuro-vascular coupling differs in these patients compared to healthy subjects. Animal studies will answer this question enabling more quantitative interpretation of the human neuroimaging studies.

Director
Neurophotonics Center




NCS-FR: Engineering Brain Circuits for Complex Scene Analysis
09/01/2023 - 08/31/2028 (Multi-PI)
PI: David A. Boas, PhD
National Science Foundation
SMA-2319321

Neurophotonic Advances for Mechanistic Investigation of the Role of Capillary Dysfunction in Stroke Recovery
09/27/2022 - 08/31/2027 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS127156-02

Computational Miniature Mesoscope for Cortex-wide, Cellular resolution Ca2+ Imaging in Freely Behaving Mice
04/01/2022 - 03/31/2027 (Co-Investigator)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS126596-02

A transformative method for functional brain imaging with Speckle Contrast Optical Spectroscopy
08/15/2023 - 07/31/2026 (Multi-PI)
PI: David A. Boas, PhD
NIH/National Institute of Biomedical Imaging & Bioengineering
1UG3EB034710-01

The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function
09/22/2020 - 05/31/2025 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
5U01EB029856-04

Time-Gated Diffuse Correlation Spectroscopy for functional imaging of the human brain
09/21/2019 - 06/30/2024 (Subcontract PI)
Massachusetts General Hospital NIH NIBIB
5U01EB028660-04

The impact of microvascular (dys)regulation on cerebral flow and oxygen heterogeneity
09/01/2018 - 05/31/2024 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS108472-05

Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain
08/22/2018 - 05/31/2024 (Multi-PI)
PI: David A. Boas, PhD
Massachusetts General Hospital NIH NIMH
5U01MH117023-05

Multispectral and Hyperspectral Preclinical Imager Spanning the Visible, NIR-I and NIR-II
09/01/2021 - 08/31/2023 (PI)
NIH/Office of the Director
1S10OD030510-01

Establishing an fNIRS Ecosystem for Open Software-Hardware Dissemination
01/01/2018 - 12/31/2022 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R24NS104096-04

Showing 10 of 24 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2023 A transformative method for functional brain imaging with Speckle Contrast Optical Spectroscopy 1UG3EB034710-01
2023 Neurophotonic Advances for Mechanistic Investigation of the Role of Capillary Dysfunction in Stroke Recovery 5R01NS127156-02
2023 Evaluating the utility of fNIRS in detecting and diagnosing AD/ADRD 3U01EB029856-04S1
2023 The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function 5U01EB029856-04
2022 The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function 5U01EB029856-03
2022 The impact of microvascular (dys)regulation on cerebral flow and oxygen heterogeneity 5R01NS108472-05
2022 Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain 5U01MH117023-05
2021 The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function 5U01EB029856-02
2021 The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function 3U01EB029856-02S1
2021 The impact of microvascular (dys)regulation on cerebral flow and oxygen heterogeneity 5R01NS108472-04 4
Showing 10 of 105 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Ning M, Duwadi S, Yücel MA, von Lühmann A, Boas DA, Sen K. fNIRS dataset during complex scene analysis. Front Hum Neurosci. 2024; 18:1329086. PMID: 38576451; PMCID: PMC10991699; DOI: 10.3389/fnhum.2024.1329086;
     
  2. Cheng S, Chang S, Li Y, Novoseltseva A, Lin S, Wu Y, Zhu J, McKee AC, Rosene DL, Wang H, Bigio IJ, Boas DA, Tian L. Enhanced Multiscale Human Brain Imaging by Semi-supervised Digital Staining and Serial Sectioning Optical Coherence Tomography. Res Sq. 2024 Mar 21.View Related Profiles. PMID: 38562721; PMCID: PMC10984089; DOI: 10.21203/rs.3.rs-4014687/v1;
     
  3. Subramaniam S, Akay M, Anastasio MA, Bailey V, Boas D, Bonato P, Chilkoti A, Cochran JR, Colvin V, Desai TA, Duncan JS, Epstein FH, Fraley S, Giachelli C, Grande-Allen KJ, Green J, Guo XE, Hilton IB, Humphrey JD, Johnson CR, Karniadakis G, King MR, Kirsch RF, Kumar S, Laurencin CT, Li S, Lieber RL, Lovell N, Mali P, Margulies SS, Meaney DF, Ogle B, Palsson B, A Peppas N, Perreault EJ, Rabbitt R, Setton LA, Shea LD, Shroff SG, Shung K, Tolias AS, van der Meulen MCH, Varghese S, Vunjak-Novakovic G, White JA, Winslow R, Zhang J, Zhang K, Zukoski C, Miller MI. Grand Challenges at the Interface of Engineering and Medicine. IEEE Open J Eng Med Biol. 2024; 5:1-13.View Related Profiles. PMID: 38415197; PMCID: PMC10896418; DOI: 10.1109/OJEMB.2024.3351717;
     
  4. Liu B, Wang Y, Fomin-Thunemann N, Thunemann M, Kilic K, Devor A, Cheng X, Tan J, Jiang J, Boas DA, Tang J. Time-Lagged Functional Ultrasound for Multi-Parametric Cerebral Hemodynamic Imaging. IEEE Trans Med Imaging. 2024 Feb; 43(2):638-648.View Related Profiles. PMID: 37703138; PMCID: PMC10947997; DOI: 10.1109/TMI.2023.3314734;
     
  5. Robinson MB, Cheng TY, Renna M, Wu MM, Kim B, Cheng X, Boas DA, Franceschini MA, Carp SA. Comparing the performance potential of speckle contrast optical spectroscopy and diffuse correlation spectroscopy for cerebral blood flow monitoring using Monte Carlo simulations in realistic head geometries. Neurophotonics. 2024 Jan; 11(1):015004. PMID: 38282721; PMCID: PMC10821780; DOI: 10.1117/1.NPh.11.1.015004;
     
  6. Ning M, Duwadi S, Yücel MA, Von Lühmann A, Boas DA, Sen K. fNIRS Dataset During Complex Scene Analysis. bioRxiv. 2024 Jan 23. PMID: 38328139; PMCID: PMC10849700; DOI: 10.1101/2024.01.23.576715;
     
  7. Vu MT, Brown EH, Wen MJ, Noggle CA, Zhang Z, Monk KJ, Bouabid S, Mroz L, Graham BM, Zhuo Y, Li Y, Otchy TM, Tian L, Davison IG, Boas DA, Howe MW. Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior. Neuron. 2024 Mar 20; 112(6):909-923.e9. PMID: 38242115; PMCID: PMC10957316; DOI: 10.1016/j.neuron.2023.12.011;
     
  8. Liu B, Postnov D, Boas DA, Cheng X. Dynamic light scattering and laser speckle contrast imaging of the brain: theory of the spatial and temporal statistics of speckle pattern evolution. Biomed Opt Express. 2024 Feb 01; 15(2):579-593. PMID: 38404305; PMCID: PMC10890898; DOI: 10.1364/BOE.510333;
     
  9. Vu MT, Brown EH, Wen MJ, Noggle CA, Zhang Z, Monk KJ, Bouabid S, Mroz L, Graham BM, Zhuo Y, Li Y, Otchy TM, Tian L, Davison IG, Boas DA, Howe MW. Targeted micro-fiber arrays for measuring and manipulating localized multi-scale neural dynamics over large, deep brain volumes during behavior. bioRxiv. 2023 Nov 17. PMID: 38014018; PMCID: PMC10680831; DOI: 10.1101/2023.11.17.567425;
     
  10. Doran PR, Fomin-Thunemann N, Tang RP, Zimmerman B, Kiliç K, Martin EA, Kura S, Fisher HP, Chabbott G, Herbert J, Jiang JX, Sakadzic S, Boas DA, Devor A, Chen IA, Thunemann M. Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination. bioRxiv. 2023 Nov 10.View Related Profiles. PMID: 37986755; PMCID: PMC10659277; DOI: 10.1101/2023.11.07.566086;
     
Showing 10 of 378 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 377 publications over 31 distinct years, with a maximum of 23 publications in 2009

YearPublications
19941
19952
19962
19974
19983
19992
20005
20014
20026
200314
20048
200519
200610
200711
200820
200923
201019
201116
201211
201317
201412
201517
201622
201721
201815
201913
202022
202117
202213
202320
20248
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