David Boas | Profiles RNS

David A. Boas, PhD

Professor

Boston University College of Engineering

Dept of Biomedical Engineering

PhD, University of Pennsylvania

Websites

	College of Engineering Faculty
	Neurophotonics Center
	BOAS Lab
	Google Scholar
	ResearchGate
	LinkedIn

ORCID : 0000-0002-6709-7711

David Boas, Ph.D. (Professor, Biomedical Engineering) is Director of the Neurophotonics Center at Boston University. He received his BS in Physics at Rensselear Polytechnic Institute and PhD in Physics at the University of Pennsylvania. During his academic career, he has supervised 44 students and post-doctoral fellows, and he has published over 250 papers that have received over 30,000 citations and an h-index of 101. He is the founding President of the Society for Functional Near Infrared Spectroscopy and founding Editor-in-Chief of the journal Neurophotonics published by SPIE. Dr. Boas was awarded the Britton Chance Award in Biomedical Optics in 2016 for his development of several novel, high-impact biomedical optical technologies in the neurosciences, as well as following through with impactful application studies, and fostering the widespread adoption of these technologies. He was elected a Fellow of AIMBE, SPIE, and OSA in 2017.

As Director of the Neurophotonics Center, he facilitates the development and application of novel optical methods to address a broad range of neuroscience questions from basic science to clinical translation. His own research efforts focus on neurovascular coupling, cerebral oxygen delivery and consumption, functional near infrared spectroscopy (fNIRS), and physiological modeling. Studies are done in rodents and humans, invasively and non-invasively, microscopically and macroscopically, providing a powerful ability to translate findings from animals to humans, and conversely to address in animals questions raised during human studies. One example of this that will tie together many of Dr. Boas’ activities is studying functional brain recovery in survivors of stroke. Human neuroimaging by fMRI and fNIRS measures hemodynamic functional recovery but it is not known if neuro-vascular coupling differs in these patients compared to healthy subjects. Animal studies will answer this question enabling more quantitative interpretation of the human neuroimaging studies.

Director
Neurophotonics Center

BU Research
NIH RePORTER Research

The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function
09/22/2020 - 05/31/2025 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering
1U01EB029856-01

Time-Gated Diffuse Correlation Spectroscopy for functional imaging of the human brain
09/21/2019 - 06/30/2024 (Subcontract PI)
Massachusetts General Hospital NIH NIBIB
5U01EB028660-02

The impact of microvascular (dys)regulation on cerebral flow and oxygen heterogeneity
09/01/2018 - 05/31/2023 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R01NS108472-03

Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain
08/22/2018 - 05/31/2023 (Subcontract PI)
Massachusetts General Hospital NIH NIMH
5U01MH117023-03

A Computational Miniature Mesoscope for Large-Scale Brain Mapping in Behaving Mice
04/01/2019 - 03/31/2022 (Multi-PI)
PI: David A. Boas, PhD
NIH/National Eye Institute
1R21EY030016-01

Comparing laser speckle contract and diffuse correlation spectroscopy measurements in human brain function
04/20/2021 - 02/01/2022 (PI)
Facebook Technologies, LLC

Establishing an fNIRS Ecosystem for Open Software-Hardware Dissemination
01/01/2018 - 12/31/2021 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R24NS104096-04

NRT UtB: Neurophotonics
09/01/2016 - 08/31/2021 (Multi-PI)
PI: David A. Boas, PhD
National Science Foundation
DGE-1633516

Improving human FMRI through modeling and imaging microvascular dynamics
11/01/2017 - 07/31/2021 (Subcontract PI)
Massachusetts General Hospital NIH NIMH
5R01MH111419-05

Gated Diffuse Correlation Spectroscopy for functional imaging of the human brain
09/25/2017 - 07/31/2021 (Subcontract PI)
General Hospital Corp d/b/a Massachusetts General Hospital NIH NIBIB
5R01EB025145-02

Showing 10 of 18 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2021	The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function	5U01EB029856-02
2021	The impact of microvascular (dys)regulation on cerebral flow and oxygen heterogeneity	5R01NS108472-04	4
2021	Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain	5U01MH117023-04	5
2021	Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain Admin Supplement	3U01MH117023-04S1	5
2021	Establishing an fNIRS Ecosystem for Open Software-Hardware Dissemination	5R24NS104096-04	1
2020	The Neuroscience of Everyday World- A novel wearable system for continuous measurement of brain function	1U01EB029856-01
2020	The impact of microvascular (dys)regulation on cerebral flow and oxygen heterogeneity	5R01NS108472-03	4
2020	Imaging and Analysis Techniques to Construct a Cell Census Atlas of the Human Brain	5U01MH117023-03	5
2020	Establishing an fNIRS Ecosystem for Open Software-Hardware Dissemination	5R24NS104096-03	1
2019	A Computational Miniature Mesoscope for Large-Scale Brain Mapping in Behaving Mice	1R21EY030016-01

Showing 10 of 100 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Cheng X, Sie EJ, Naufel S, Boas DA, Marsili F. Measuring neuronal activity with diffuse correlation spectroscopy: a theoretical investigation. Neurophotonics. 2021 Jul; 8(3):035004. PMID: 34368390; PMCID: PMC8339443; DOI: 10.1117/1.NPh.8.3.035004;

Aykan SA, Xie H, Lai JH, Zheng Y, Chung DY, Kura S, Anzabi M, Sugimoto K, McAllister LM, Yaseen MA, Boas DA, Whalen MJ, Sakadzic S, Ayata C. Focal Subcortical White Matter Lesions Disrupt Resting State Cortical Interhemispheric Functional Connectivity in Mice. Cereb Cortex. 2021 May 25. PMID: 34037216

Liu C, Kiliç K, Erdener SE, Boas DA, Postnov DD. Choosing a model for laser speckle contrast imaging. Biomed Opt Express. 2021 Jun 01; 12(6):3571-3583. PMID: 34221679; PMCID: PMC8221943; DOI: 10.1364/BOE.426521;

Hartung G, Badr S, Mihelic S, Dunn A, Cheng X, Kura S, Boas DA, Kleinfeld D, Alaraj A, Linninger AA. Mathematical synthesis of the cortical circulation for the whole mouse brain-part II: Microcirculatory closure. Microcirculation. 2021 07; 28(5):e12687. PMID: 33615601

Tang J, Cheng X, Kilic K, Devor A, Lee J, Boas DA. Imaging localized fast optical signals of neural activation with optical coherence tomography in awake mice. Opt Lett. 2021 Apr 01; 46(7):1744-1747. PMID: 33793533; PMCID: PMC8086197; DOI: 10.1364/OL.411897;

Shao W, Kilic K, Yin W, Wirak G, Qin X, Feng H, Boas D, Gabel CV, Yi J. Wide field-of-view volumetric imaging by a mesoscopic scanning oblique plane microscopy with switchable objective lenses. Quant Imaging Med Surg. 2021 Mar; 11(3):983-997.View Related Profiles.

Gabel, Christopher
Boas, David
Wirak, Gregory
Feng, Hui
Yin, Wenqing
Qin, Xiaodan

PMID: 33654671; PMCID: PMC7829172; DOI: 10.21037/qims-20-806;

Anzabi M, Li B, Wang H, Kura S, Sakadžic S, Boas D, Østergaard L, Ayata C. Optical coherence tomography of arteriolar diameter and capillary perfusion during spreading depolarizations. J Cereb Blood Flow Metab. 2021 Sep; 41(9):2256-2263. PMID: 33593116; PMCID: PMC8393288; DOI: 10.1177/0271678X21994013;

Cheng X, Sie EJ, Boas DA, Marsili F. Choosing an optimal wavelength to detect brain activity in functional near-infrared spectroscopy. Opt Lett. 2021 Feb 15; 46(4):924-927. PMID: 33577549

Mächler P, Broggini T, Mateo C, Thunemann M, Fomin-Thunemann N, Doran PR, Sencan I, Kilic K, Desjardins M, Uhlirova H, Yaseen MA, Boas DA, Linninger AA, Vergassola M, Yu X, Lewis LD, Polimeni JR, Rosen BR, Sakadžic S, Buxton RB, Lauritzen M, Kleinfeld D, Devor A. A Suite of Neurophotonic Tools to Underpin the Contribution of Internal Brain States in fMRI. Curr Opin Biomed Eng. 2021 Jun; 18. PMID: 33959688; PMCID: PMC8095678; DOI: 10.1016/j.cobme.2021.100273;

Yücel MA, Lühmann AV, Scholkmann F, Gervain J, Dan I, Ayaz H, Boas D, Cooper RJ, Culver J, Elwell CE, Eggebrecht A, Franceschini MA, Grova C, Homae F, Lesage F, Obrig H, Tachtsidis I, Tak S, Tong Y, Torricelli A, Wabnitz H, Wolf M. Errata: Best practices for fNIRS publications. Neurophotonics. 2021 Jan; 8(1):019802. PMID: 33575435; PMCID: PMC7868645; DOI: 10.1117/1.NPh.8.1.019802;

Showing 10 of 332 results. Show More

von Lühmann A, Zheng Y, Ortega-Martinez A, Kiran S, Somers DC, Cronin-Golomb A, Awad LN, Ellis TD, Boas DA, Yücel MA. Towards Neuroscience of the Everyday World (NEW) using functional Near-Infrared Spectroscopy. Curr Opin Biomed Eng. 2021 Jun; 18.View Related Profiles.

Cronin-Golomb, Alice
Boas, David
Awad, Louis

PMID: 33709044; PMCID: PMC7943029; DOI: 10.1016/j.cobme.2021.100272;

Tang J, Kilic K, Szabo TL, Boas DA. Improved Color Doppler for Cerebral Blood Flow Axial Velocity Imaging. IEEE Trans Med Imaging. 2021 02; 40(2):758-764. PMID: 33156785; PMCID: PMC8098776; DOI: 10.1109/TMI.2020.3036468;

Kiliç K, Desjardins M, Tang J, Thunemann M, Sunil S, Erdener SE, Postnov DD, Boas DA, Devor A. Chronic Cranial Windows for Long Term Multimodal Neurovascular Imaging in Mice. Front Physiol. 2020; 11:612678. PMID: 33551837; PMCID: PMC7862556; DOI: 10.3389/fphys.2020.612678;

Yücel MA, Lühmann AV, Scholkmann F, Gervain J, Dan I, Ayaz H, Boas D, Cooper RJ, Culver J, Elwell CE, Eggebrecht A, Franceschini MA, Grova C, Homae F, Lesage F, Obrig H, Tachtsidis I, Tak S, Tong Y, Torricelli A, Wabnitz H, Wolf M. Best practices for fNIRS publications. Neurophotonics. 2021 Jan; 8(1):012101. PMID: 33442557; PMCID: PMC7793571; DOI: 10.1117/1.NPh.8.1.012101;

Sunil S, Evren Erdener S, Cheng X, Kura S, Tang J, Jiang J, Karrobi K, Kiliç K, Roblyer D, Boas DA. Stroke core revealed by tissue scattering using spatial frequency domain imaging. Neuroimage Clin. 2021; 29:102539. PMID: 33385882; PMCID: PMC7779322; DOI: 10.1016/j.nicl.2020.102539;

Postnov DD, Tang J, Erdener SE, Kiliç K, Boas DA. Dynamic light scattering imaging. Sci Adv. 2020 Nov; 6(45). PMID: 33158865; PMCID: PMC7673709; DOI: 10.1126/sciadv.abc4628;

Bordoni L, Li B, Kura S, Boas DA, Sakadžic S, Østergaard L, Frische S, Gutiérrez-Jiménez E. Quantification of Capillary Perfusion in an Animal Model of Acute Intracranial Hypertension. J Neurotrauma. 2021 02 15; 38(4):446-454. PMID: 32998634; PMCID: PMC8020532; DOI: 10.1089/neu.2019.6901;

Xue Y, Davison IG, Boas DA, Tian L. Single-shot 3D wide-field fluorescence imaging with a Computational Miniature Mesoscope. Sci Adv. 2020 Oct; 6(43). PMID: 33087364; PMCID: PMC7577725; DOI: 10.1126/sciadv.abb7508;

Yang J, Chen IA, Chang S, Tang J, Lee B, Kiliç K, Sunil S, Wang H, Varadarajan D, Magnain C, Chen SC, Costantini I, Pavone F, Fischl B, Boas DA. Improving the characterization of ex vivo human brain optical properties using high numerical aperture optical coherence tomography by spatially constraining the confocal parameters. Neurophotonics. 2020 Oct; 7(4):045005. PMID: 33094126; PMCID: PMC7575831; DOI: 10.1117/1.NPh.7.4.045005;

von Lühmann A, Li X, Gilmore N, Boas DA, Yücel MA. Open Access Multimodal fNIRS Resting State Dataset With and Without Synthetic Hemodynamic Responses. Front Neurosci. 2020; 14:579353. PMID: 33132833; PMCID: PMC7550457; DOI: 10.3389/fnins.2020.579353;

Chung DY, Oka F, Jin G, Harriott A, Kura S, Aykan SA, Qin T, Edmiston WJ, Lee H, Yaseen MA, Sakadžic S, Boas DA, Whalen MJ, Ayata C. Subarachnoid hemorrhage leads to early and persistent functional connectivity and behavioral changes in mice. J Cereb Blood Flow Metab. 2021 05; 41(5):975-985. PMID: 32936728; PMCID: PMC8054726; DOI: 10.1177/0271678X20940152;

Robinson M, Boas D, Sakadžic S, Franceschini MA, Carp S. Interferometric diffuse correlation spectroscopy improves measurements at long source-detector separation and low photon count rate. J Biomed Opt. 2020 09; 25(9). PMID: 33000571; PMCID: PMC7525153; DOI: 10.1117/1.JBO.25.9.097004;

Kiliç K, Tang J, Erdener SE, Sunil S, Giblin JT, Lee BS, Postnov DD, Chen A, Boas DA. Chronic Imaging of Mouse Brain: From Optical Systems to Functional Ultrasound. Curr Protoc Neurosci. 2020 09; 93(1):e98. PMID: 32584495; PMCID: PMC7441818; DOI: 10.1002/cpns.98;

Tang J, Postnov DD, Kilic K, Erdener SE, Lee B, Giblin JT, Szabo TL, Boas DA. Functional Ultrasound Speckle Decorrelation-Based Velocimetry of the Brain. Adv Sci (Weinh). 2020 Sep; 7(18):2001044. PMID: 32999839; PMCID: PMC7509671; DOI: 10.1002/advs.202001044;

Li X, Krol MA, Jahani S, Boas DA, Tager-Flusberg H, Yücel MA. Brain correlates of motor complexity during observed and executed actions. Sci Rep. 2020 07 03; 10(1):10965.View Related Profiles.

Boas, David
Tager-Flusberg, Helen

PMID: 32620887; PMCID: PMC7335074; DOI: 10.1038/s41598-020-67327-5;

Sencan I, Esipova T, Kiliç K, Li B, Desjardins M, Yaseen MA, Wang H, Porter JE, Kura S, Fu B, Secomb TW, Boas DA, Vinogradov SA, Devor A, Sakadžic S. Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation. J Cereb Blood Flow Metab. 2020 Jun 09; 271678X20928011. PMID: 32515672

Celaya-Alcala JT, Lee GV, Smith AF, Li B, Sakadžic S, Boas DA, Secomb TW. Simulation of oxygen transport and estimation of tissue perfusion in extensive microvascular networks: Application to cerebral cortex. J Cereb Blood Flow Metab. 2021 03; 41(3):656-669. PMID: 32501155; PMCID: PMC7922761; DOI: 10.1177/0271678X20927100;

Cheng X, Sadegh S, Zilpelwar S, Devor A, Tian L, Boas DA. Comparing the fundamental imaging depth limit of two-photon, three-photon, and non-degenerate two-photon microscopy. Opt Lett. 2020 May 15; 45(10):2934-2937. PMID: 32412504; PMCID: PMC8059139; DOI: 10.1364/OL.392724;

Robinson MB, Carp SA, Peruch A, Boas DA, Franceschini MA, Sakadžic S. Characterization of continuous wave ultrasound for acousto-optic modulated diffuse correlation spectroscopy (AOM-DCS). Biomed Opt Express. 2020 Jun 01; 11(6):3071-3090. PMID: 32637242; PMCID: PMC7316011; DOI: 10.1364/BOE.390322;

Tamborini D, Franceschini MA, Stephens KA, Wu MM, Farzam P, Siegel AM, Shatrovoy O, Blackwell M, Boas DA, Carp SA. Corrections to "Portable System for Time-Domain Diffuse Correlation Spectroscopy". IEEE Trans Biomed Eng. 2020 04; 67(4):1229. PMID: 32203016

Erdener SE, Tang J, Kiliç K, Postnov D, Giblin JT, Kura S, Chen IA, Vayisoglu T, Sakadžic S, Schaffer CB, Boas DA. Dynamic capillary stalls in reperfused ischemic penumbra contribute to injury: A hyperacute role for neutrophils in persistent traffic jams. J Cereb Blood Flow Metab. 2021 02; 41(2):236-252. PMID: 32237951

Jones R, Grisot G, Augustinack J, Magnain C, Boas DA, Fischl B, Wang H, Yendiki A. Insight into the fundamental trade-offs of diffusion MRI from polarization-sensitive optical coherence tomography in ex vivo human brain. Neuroimage. 2020 07 01; 214:116704. PMID: 32151760

Selb J, Wu KC, Sutin J, Lin PI, Farzam P, Bechek S, Shenoy A, Patel AB, Boas DA, Franceschini MA, Rosenthal ES. Erratum: Prolonged monitoring of cerebral blood flow and autoregulation with diffuse correlation spectroscopy in neurocritical care patients. Neurophotonics. 2020 01; 7(1):019801. PMID: 32118087; PMCID: PMC7032410; DOI: 10.1117/1.NPh.7.1.019801;

von Lühmann A, Ortega-Martinez A, Boas DA, Yücel MA. Using the General Linear Model to Improve Performance in fNIRS Single Trial Analysis and Classification: A Perspective. Front Hum Neurosci. 2020; 14:30. PMID: 32132909; PMCID: PMC7040364; DOI: 10.3389/fnhum.2020.00030;

Sunil S, Erdener SE, Lee BS, Postnov D, Tang J, Kura S, Cheng X, Chen IA, Boas DA, Kiliç K. Awake chronic mouse model of targeted pial vessel occlusion via photothrombosis. Neurophotonics. 2020 Jan; 7(1):015005. PMID: 32042854; PMCID: PMC6992450; DOI: 10.1117/1.NPh.7.1.015005;

von Lühmann A, Li X, Müller KR, Boas DA, Yücel MA. Improved physiological noise regression in fNIRS: A multimodal extension of the General Linear Model using temporally embedded Canonical Correlation Analysis. Neuroimage. 2020 03; 208:116472. PMID: 31870944; PMCID: PMC7703677; DOI: 10.1016/j.neuroimage.2019.116472;

Cheng X, Li Y, Mertz J, Sakadžic S, Devor A, Boas DA, Tian L. Development of a beam propagation method to simulate the point spread function degradation in scattering media. Opt Lett. 2019 Oct 15; 44(20):4989-4992. PMID: 31613246; PMCID: PMC6889808; DOI: 10.1364/OL.44.004989;

Ortega-Martinez A, Zimmermann B, Cheng X, Li X, Yucel MA, Boas DA. Contribution of speckle noise in near-infrared spectroscopy measurements. J Biomed Opt. 2019 10; 24(10):1-6. PMID: 31668028; PMCID: PMC6820049; DOI: 10.1117/1.JBO.24.10.105003;

Sadegh S, Yang MH, Ferri CGL, Thunemann M, Saisan PA, Wei Z, Rodriguez EA, Adams SR, Kiliç K, Boas DA, Sakadžic S, Devor A, Fainman Y. Efficient non-degenerate two-photon excitation for fluorescence microscopy. Opt Express. 2019 Sep 30; 27(20):28022-28035. PMID: 31684560; PMCID: PMC6825618; DOI: 10.1364/OE.27.028022;

Secomb TW, Bullock KV, Boas DA, Sakadžic S. The mass transfer coefficient for oxygen transport from blood to tissue in cerebral cortex. J Cereb Blood Flow Metab. 2020 08; 40(8):1634-1646. PMID: 31423930; PMCID: PMC7370375; DOI: 10.1177/0271678X19870068;

Li B, Esipova TV, Sencan I, Kiliç K, Fu B, Desjardins M, Moeini M, Kura S, Yaseen MA, Lesage F, Østergaard L, Devor A, Boas DA, Vinogradov SA, Sakadžic S. More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction. Elife. 2019 07 15; 8. PMID: 31305237; PMCID: PMC6636997; DOI: 10.7554/eLife.42299;

Xie H, Chung DY, Kura S, Sugimoto K, Aykan SA, Wu Y, Sakadžic S, Yaseen MA, Boas DA, Ayata C. Differential effects of anesthetics on resting state functional connectivity in the mouse. J Cereb Blood Flow Metab. 2020 04; 40(4):875-884. PMID: 31092086; PMCID: PMC7168791; DOI: 10.1177/0271678X19847123;

Li B, Ohtomo R, Thunemann M, Adams SR, Yang J, Fu B, Yaseen MA, Ran C, Polimeni JR, Boas DA, Devor A, Lo EH, Arai K, Sakadžic S. Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion. J Cereb Blood Flow Metab. 2020 03; 40(3):501-512. PMID: 30829101; PMCID: PMC7026840; DOI: 10.1177/0271678X19831016;

Tang J, Erdener SE, Sunil S, Boas DA. Normalized field autocorrelation function-based optical coherence tomography three-dimensional angiography. J Biomed Opt. 2019 03; 24(3):1-8. PMID: 30868803; PMCID: PMC6414735; DOI: 10.1117/1.JBO.24.3.036005;

Postnov DD, Cheng X, Erdener SE, Boas DA. Choosing a laser for laser speckle contrast imaging. Sci Rep. 2019 02 22; 9(1):2542. PMID: 30796288; PMCID: PMC6385248; DOI: 10.1038/s41598-019-39137-x;

Tamborini D, Stephens KA, Wu MM, Farzam P, Siegel AM, Shatrovoy O, Blackwell M, Boas DA, Carp SA, Franceschini MA. Portable System for Time-Domain Diffuse Correlation Spectroscopy. IEEE Trans Biomed Eng. 2019 11; 66(11):3014-3025. PMID: 30794161; PMCID: PMC7216142; DOI: 10.1109/TBME.2019.2899762;

Moeini M, Lu X, Bélanger S, Picard F, Boas D, Kakkar A, Lesage F. Cerebral tissue pO2 response to stimulation is preserved with age in awake mice. Neurosci Lett. 2019 04 23; 699:160-166. PMID: 30738870; PMCID: PMC6487491; DOI: 10.1016/j.neulet.2019.02.007;

Cheng X, Berman AJL, Polimeni JR, Buxton RB, Gagnon L, Devor A, Sakadžic S, Boas DA. Dependence of the MR signal on the magnetic susceptibility of blood studied with models based on real microvascular networks. Magn Reson Med. 2019 06; 81(6):3865-3874. PMID: 30659643; PMCID: PMC6435380; DOI: 10.1002/mrm.27660;

Perkins LN, Devor A, Gardner TJ, Boas DA. Extracting individual neural activity recorded through splayed optical microfibers. Neurophotonics. 2018 Oct; 5(4):045009. PMID: 30627593; PMCID: PMC6311456; DOI: 10.1117/1.NPh.5.4.045009;

Desjardins M, Kiliç K, Thunemann M, Mateo C, Holland D, Ferri CGL, Cremonesi JA, Li B, Cheng Q, Weldy KL, Saisan PA, Kleinfeld D, Komiyama T, Liu TT, Bussell R, Wong EC, Scadeng M, Dunn AK, Boas DA, Sakadžic S, Mandeville JB, Buxton RB, Dale AM, Devor A. Awake Mouse Imaging: From Two-Photon Microscopy to Blood Oxygen Level-Dependent Functional Magnetic Resonance Imaging. Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 06; 4(6):533-542. PMID: 30691968; PMCID: PMC6556427; DOI: 10.1016/j.bpsc.2018.12.002;

Damseh R, Pouliot P, Gagnon L, Sakadzic S, Boas D, Cheriet F, Lesage F. Automatic Graph-Based Modeling of Brain Microvessels Captured With Two-Photon Microscopy. IEEE J Biomed Health Inform. 2019 11; 23(6):2551-2562. PMID: 30507542; PMCID: PMC6546554; DOI: 10.1109/JBHI.2018.2884678;

Sencan I, Esipova TV, Yaseen MA, Fu B, Boas DA, Vinogradov SA, Shahidi M, Sakadžic S. Two-photon phosphorescence lifetime microscopy of retinal capillary plexus oxygenation in mice. J Biomed Opt. 2018 12; 23(12):1-9. PMID: 30516039; PMCID: PMC6278707; DOI: 10.1117/1.JBO.23.12.126501;

Postnov DD, Erdener SE, Kilic K, Boas DA. Cardiac pulsatility mapping and vessel type identification using laser speckle contrast imaging. Biomed Opt Express. 2018 Dec 01; 9(12):6388-6397. PMID: 31065436; PMCID: PMC6491022; DOI: 10.1364/BOE.9.006388;

Selb J, Wu KC, Sutin J, Lin PI, Farzam P, Bechek S, Shenoy A, Patel AB, Boas DA, Franceschini MA, Rosenthal ES. Prolonged monitoring of cerebral blood flow and autoregulation with diffuse correlation spectroscopy in neurocritical care patients. Neurophotonics. 2018 Oct; 5(4):045005. PMID: 30450363; PMCID: PMC6233866; DOI: 10.1117/1.NPh.5.4.045005;

Magnain C, Augustinack JC, Tirrell L, Fogarty M, Frosch MP, Boas D, Fischl B, Rockland KS. Colocalization of neurons in optical coherence microscopy and Nissl-stained histology in Brodmann's area 32 and area 21. Brain Struct Funct. 2019 Jan; 224(1):351-362.View Related Profiles.

Boas, David
Rockland, Kathleen

PMID: 30328512; PMCID: PMC6369026; DOI: 10.1007/s00429-018-1777-z;

Peng K, Yücel MA, Steele SC, Bittner EA, Aasted CM, Hoeft MA, Lee A, George EE, Boas DA, Becerra L, Borsook D. Morphine Attenuates fNIRS Signal Associated With Painful Stimuli in the Medial Frontopolar Cortex (medial BA 10). Front Hum Neurosci. 2018; 12:394. PMID: 30349466; PMCID: PMC6186992; DOI: 10.3389/fnhum.2018.00394;

Perkins LN, Semu D, Shen J, Boas DA, Gardner TJ. High-density microfibers as a potential optical interface to reach deep brain regions. J Neural Eng. 2018 12; 15(6):066002. PMID: 30127101; PMCID: PMC6239906; DOI: 10.1088/1741-2552/aadbb2;

Cheng X, Tamborini D, Carp SA, Shatrovoy O, Zimmerman B, Tyulmankov D, Siegel A, Blackwell M, Franceschini MA, Boas DA. Time domain diffuse correlation spectroscopy: modeling the effects of laser coherence length and instrument response function. Opt Lett. 2018 Jun 15; 43(12):2756-2759. PMID: 29905681; PMCID: PMC6197052; DOI: 10.1364/OL.43.002756;

Moeini M, Lu X, Avti PK, Damseh R, Bélanger S, Picard F, Boas D, Kakkar A, Lesage F. Compromised microvascular oxygen delivery increases brain tissue vulnerability with age. Sci Rep. 2018 05 29; 8(1):8219. PMID: 29844478; PMCID: PMC5974237; DOI: 10.1038/s41598-018-26543-w;

Kisler K, Lazic D, Sweeney MD, Plunkett S, El Khatib M, Vinogradov SA, Boas DA, Sakadži S, Zlokovic BV. In vivo imaging and analysis of cerebrovascular hemodynamic responses and tissue oxygenation in the mouse brain. Nat Protoc. 2018 06; 13(6):1377-1402. PMID: 29844521; PMCID: PMC6402338; DOI: 10.1038/nprot.2018.034;

Gómez CA, Sutin J, Wu W, Fu B, Uhlirova H, Devor A, Boas DA, Sakadžic S, Yaseen MA. Phasor analysis of NADH FLIM identifies pharmacological disruptions to mitochondrial metabolic processes in the rodent cerebral cortex. PLoS One. 2018; 13(3):e0194578. PMID: 29561904; PMCID: PMC5862490; DOI: 10.1371/journal.pone.0194578;

Kura S, Xie H, Fu B, Ayata C, Boas DA, Sakadžic S. Intrinsic optical signal imaging of the blood volume changes is sufficient for mapping the resting state functional connectivity in the rodent cortex. J Neural Eng. 2018 06; 15(3):035003. PMID: 29451130; PMCID: PMC5927826; DOI: 10.1088/1741-2552/aaafe4;

Jahani S, Setarehdan SK, Boas DA, Yücel MA. Motion artifact detection and correction in functional near-infrared spectroscopy: a new hybrid method based on spline interpolation method and Savitzky-Golay filtering. Neurophotonics. 2018 Jan; 5(1):015003. PMID: 29430471; PMCID: PMC5803523; DOI: 10.1117/1.NPh.5.1.015003;

Boas DA. Special Section Guest Editorial: Special Issue from SPIE Brain 2017. Neurophotonics. 2017 Oct; 4(4):041500. PMID: 29296628; PMCID: PMC5746058; DOI: 10.1117/1.NPh.4.4.041500;

Erdener SE, Tang J, Sajjadi A, Kiliç K, Kura S, Schaffer CB, Boas DA. Spatio-temporal dynamics of cerebral capillary segments with stalling red blood cells. J Cereb Blood Flow Metab. 2019 05; 39(5):886-900. PMID: 29168661; PMCID: PMC6501506; DOI: 10.1177/0271678X17743877;

Wang H, Magnain C, Sakadžic S, Fischl B, Boas DA. Characterizing the optical properties of human brain tissue with high numerical aperture optical coherence tomography. Biomed Opt Express. 2017 Dec 01; 8(12):5617-5636. PMID: 29296492; PMCID: PMC5745107; DOI: 10.1364/BOE.8.005617;

Peng K, Yücel MA, Aasted CM, Steele SC, Boas DA, Borsook D, Becerra L. Using prerecorded hemodynamic response functions in detecting prefrontal pain response: a functional near-infrared spectroscopy study. Neurophotonics. 2018 Jan; 5(1):011018. PMID: 29057285; PMCID: PMC5641587; DOI: 10.1117/1.NPh.5.1.011018;

Wang H, Magnain C, Wang R, Dubb J, Varjabedian A, Tirrell LS, Stevens A, Augustinack JC, Konukoglu E, Aganj I, Frosch MP, Schmahmann JD, Fischl B, Boas DA. as-PSOCT: Volumetric microscopic imaging of human brain architecture and connectivity. Neuroimage. 2018 Jan 15; 165:56-68. PMID: 29017866; PMCID: PMC5732037; DOI: 10.1016/j.neuroimage.2017.10.012;

Yücel MA, Selb JJ, Huppert TJ, Franceschini MA, Boas DA. Functional Near Infrared Spectroscopy: Enabling Routine Functional Brain Imaging. Curr Opin Biomed Eng. 2017 Dec; 4:78-86. PMID: 29457144; PMCID: PMC5810962; DOI: 10.1016/j.cobme.2017.09.011;

Tang J, Erdener SE, Fu B, Boas DA. Capillary red blood cell velocimetry by phase-resolved optical coherence tomography. Opt Lett. 2017 Oct 01; 42(19):3976-3979. PMID: 28957175; PMCID: PMC5972360; DOI: 10.1364/OL.42.003976;

Tamborini D, Farzam P, Zimmermann B, Wu KC, Boas DA, Franceschini MA. Development and characterization of a multidistance and multiwavelength diffuse correlation spectroscopy system. Neurophotonics. 2018 Jan; 5(1):011015. PMID: 28948194; PMCID: PMC5607257; DOI: 10.1117/1.NPh.5.1.011015;

Jahani S, Fantana AL, Harper D, Ellison JM, Boas DA, Forester BP, Yücel MA. fNIRS can robustly measure brain activity during memory encoding and retrieval in healthy subjects. Sci Rep. 2017 08 25; 7(1):9533. PMID: 28842618; PMCID: PMC5572719; DOI: 10.1038/s41598-017-09868-w;

Leproux, O'Sullivan TD, Cerussi A, Durkin A, Hill B, Hylton N, Yodh AG, Carp SA, Boas D, Jiang S, Paulsen KD, Pogue B, Roblyer D, Yang W, Tromberg BJ. Performance assessment of diffuse optical spectroscopic imaging instruments in a 2-year multicenter breast cancer trial J Biomed Opt. 2017 12 01; 22(12):121604. PMID: 29389104; PMCID: PMC5995138; DOI: 10.1117/1.JBO.22.12.121604;

Tang J, Erdener SE, Li B, Fu B, Sakadzic S, Carp SA, Lee J, Boas DA. Shear-induced diffusion of red blood cells measured with dynamic light scattering-optical coherence tomography. J Biophotonics. 2018 02; 11(2). PMID: 28700129; PMCID: PMC5766442; DOI: 10.1002/jbio.201700070;

Schytz HW, Amin FM, Selb J, Boas DA. Non-invasive methods for measuring vascular changes in neurovascular headaches. J Cereb Blood Flow Metab. 2019 04; 39(4):633-649. PMID: 28782410; PMCID: PMC6446419; DOI: 10.1177/0271678X17724138;

Rasmussen PM, Smith AF, Sakadžic S, Boas DA, Pries AR, Secomb TW, Østergaard L. Model-based inference from microvascular measurements: Combining experimental measurements and model predictions using a Bayesian probabilistic approach. Microcirculation. 2017 May; 24(4). PMID: 27987383; PMCID: PMC5432377; DOI: 10.1111/micc.12343;

Yaseen MA, Sutin J, Wu W, Fu B, Uhlirova H, Devor A, Boas DA, Sakadžic S. Fluorescence lifetime microscopy of NADH distinguishes alterations in cerebral metabolism in vivo. Biomed Opt Express. 2017 May 01; 8(5):2368-2385.View Related Profiles.

Boas, David
Sutin, Jason

PMID: 28663879; PMCID: PMC5480486; DOI: 10.1364/BOE.8.002368;

Zimmermann BB, Deng B, Singh B, Martino M, Selb J, Fang Q, Sajjadi AY, Cormier J, Moore RH, Kopans DB, Boas DA, Saksena MA, Carp SA. Multimodal breast cancer imaging using coregistered dynamic diffuse optical tomography and digital breast tomosynthesis. J Biomed Opt. 2017 04 01; 22(4):46008. PMID: 28447102; PMCID: PMC5406652; DOI: 10.1117/1.JBO.22.4.046008;

Sakadžic S, Boas DA, Carp S. Theoretical model of blood flow measurement by diffuse correlation spectroscopy. J Biomed Opt. 2017 02 01; 22(2):27006. PMID: 28241276; PMCID: PMC5325034; DOI: 10.1117/1.JBO.22.2.027006;

Kisler K, Nelson AR, Rege SV, Ramanathan A, Wang Y, Ahuja A, Lazic D, Tsai PS, Zhao Z, Zhou Y, Boas DA, Sakadžic S, Zlokovic BV. Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain. Nat Neurosci. 2017 Mar; 20(3):406-416. PMID: 28135240; PMCID: PMC5323291; DOI: 10.1038/nn.4489;

Sajjadi AY, Isakoff SJ, Deng B, Singh B, Wanyo CM, Fang Q, Specht MC, Schapira L, Moy B, Bardia A, Boas DA, Carp SA. Normalization of compression-induced hemodynamics in patients responding to neoadjuvant chemotherapy monitored by dynamic tomographic optical breast imaging (DTOBI). Biomed Opt Express. 2017 Feb 01; 8(2):555-569. PMID: 28270967; PMCID: PMC5330555; DOI: 10.1364/BOE.8.000555;

Li B, Wang H, Fu B, Wang R, Sakadžic S, Boas DA. Impact of temporal resolution on estimating capillary RBC-flux with optical coherence tomography. J Biomed Opt. 2017 01 01; 22(1):16014. PMID: 28125157; PMCID: PMC5266917; DOI: 10.1117/1.JBO.22.1.016014;

Moult EM, Choi W, Boas DA, Baumann B, Clermont AC, Feener EP, Fujimoto JG. Evaluating anesthetic protocols for functional blood flow imaging in the rat eye. J Biomed Opt. 2017 01 01; 22(1):16005. PMID: 28056146; PMCID: PMC5217081; DOI: 10.1117/1.JBO.22.1.016005;

Xu K, Boas DA, Sakadžic S, LaManna JC. Brain Tissue PO2 Measurement During Normoxia and Hypoxia Using Two-Photon Phosphorescence Lifetime Microscopy. Adv Exp Med Biol. 2017; 977:149-153. PMID: 28685439; PMCID: PMC6437765; DOI: 10.1007/978-3-319-55231-6_20;

Pouliot P, Gagnon L, Lam T, Avti PK, Bowen C, Desjardins M, Kakkar AK, Thorin E, Sakadzic S, Boas DA, Lesage F. Magnetic resonance fingerprinting based on realistic vasculature in mice. Neuroimage. 2017 Apr 01; 149:436-445. PMID: 28043909; PMCID: PMC5368007; DOI: 10.1016/j.neuroimage.2016.12.060;

Lee J, Gursoy-Ozdemir Y, Fu B, Boas DA, Dalkara T. Optical coherence tomography imaging of capillary reperfusion after ischemic stroke. Appl Opt. 2016 Nov 20; 55(33):9526-9531. PMID: 27869849; PMCID: PMC6420785; DOI: 10.1364/AO.55.009526;

Aasted CM, Yücel MA, Steele SC, Peng K, Boas DA, Becerra L, Borsook D. Frontal Lobe Hemodynamic Responses to Painful Stimulation: A Potential Brain Marker of Nociception. PLoS One. 2016; 11(11):e0165226. PMID: 27806119; PMCID: PMC5091745; DOI: 10.1371/journal.pone.0165226;

Sakadžic S, Yaseen MA, Jaswal R, Roussakis E, Dale AM, Buxton RB, Vinogradov SA, Boas DA, Devor A. Two-photon microscopy measurement of cerebral metabolic rate of oxygen using periarteriolar oxygen concentration gradients. Neurophotonics. 2016 Oct; 3(4):045005. PMID: 27774493; PMCID: PMC5066455; DOI: 10.1117/1.NPh.3.4.045005;

Boujelben A, Watson M, McDougall S, Yen YF, Gerstner ER, Catana C, Deisboeck T, Batchelor TT, Boas D, Rosen B, Kalpathy-Cramer J, Chaplain MA. Multimodality imaging and mathematical modelling of drug delivery to glioblastomas. Interface Focus. 2016 Oct 06; 6(5):20160039. PMID: 27708763; PMCID: PMC4992742; DOI: 10.1098/rsfs.2016.0039;

Gagnon L, Sakadžic S, Lesage F, Pouliot P, Dale AM, Devor A, Buxton RB, Boas DA. Validation and optimization of hypercapnic-calibrated fMRI from oxygen-sensitive two-photon microscopy. Philos Trans R Soc Lond B Biol Sci. 2016 10 05; 371(1705). PMID: 27574311; PMCID: PMC5003859; DOI: 10.1098/rstb.2015.0359;

Uhlirova H, Kiliç K, Tian P, Sakadžic S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yaseen MA, Hagler DJ, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, Masliah E, Kleinfeld D, Vinogradov S, Buxton RB, Einevoll GT, Boas DA, Dale AM, Devor A. The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements. Philos Trans R Soc Lond B Biol Sci. 2016 10 05; 371(1705). PMID: 27574309; PMCID: PMC5003857; DOI: 10.1098/rstb.2015.0356;

Sutin J, Zimmerman B, Tyulmankov D, Tamborini D, Wu KC, Selb J, Gulinatti A, Rech I, Tosi A, Boas DA, Franceschini MA. Time-domain diffuse correlation spectroscopy. Optica. 2016 Sep; 3(9):1006-1013. PMID: 28008417; PMCID: PMC5166986; DOI: 10.1364/OPTICA.3.001006;

Gagnon L, Smith AF, Boas DA, Devor A, Secomb TW, Sakadžic S. Modeling of Cerebral Oxygen Transport Based on In vivo Microscopic Imaging of Microvascular Network Structure, Blood Flow, and Oxygenation. Front Comput Neurosci. 2016; 10:82. PMID: 27630556; PMCID: PMC5006088; DOI: 10.3389/fncom.2016.00082;

Tromberg BJ, Zhang Z, Leproux A, O'Sullivan TD, Cerussi AE, Carpenter PM, Mehta RS, Roblyer D, Yang W, Paulsen KD, Pogue BW, Jiang S, Kaufman PA, Yodh AG, Chung SH, Schnall M, Snyder BS, Hylton N, Boas DA, Carp SA, Isakoff SJ, Mankoff D. Predicting Responses to Neoadjuvant Chemotherapy in Breast Cancer: ACRIN 6691 Trial of Diffuse Optical Spectroscopic Imaging. Cancer Res. 2016 10 15; 76(20):5933-5944. PMID: 27527559; PMCID: PMC5148152; DOI: 10.1158/0008-5472.CAN-16-0346;

Yücel MA, Selb J, Aasted CM, Lin PY, Borsook D, Becerra L, Boas DA. Mayer waves reduce the accuracy of estimated hemodynamic response functions in functional near-infrared spectroscopy. Biomed Opt Express. 2016 Aug 01; 7(8):3078-88. PMID: 27570699; PMCID: PMC4986815; DOI: 10.1364/BOE.7.003078;

Kussman BD, Aasted CM, Yücel MA, Steele SC, Alexander ME, Boas DA, Borsook D, Becerra L. Capturing Pain in the Cortex during General Anesthesia: Near Infrared Spectroscopy Measures in Patients Undergoing Catheter Ablation of Arrhythmias. PLoS One. 2016; 11(7):e0158975. PMID: 27415436; PMCID: PMC4944937; DOI: 10.1371/journal.pone.0158975;

Biondi M, Boas DA, Wilcox T. On the other hand: Increased cortical activation to human versus mechanical hands in infants. Neuroimage. 2016 Nov 01; 141:143-153. PMID: 27417344; PMCID: PMC5026947; DOI: 10.1016/j.neuroimage.2016.07.021;

Boas DA, Sakadžic S, Selb J, Farzam P, Franceschini MA, Carp SA. Establishing the diffuse correlation spectroscopy signal relationship with blood flow. Neurophotonics. 2016 Jul; 3(3):031412. PMID: 27335889; PMCID: PMC4904065; DOI: 10.1117/1.NPh.3.3.031412;

Uhlirova H, Kiliç K, Tian P, Thunemann M, Desjardins M, Saisan PA, Sakadžic S, Ness TV, Mateo C, Cheng Q, Weldy KL, Razoux F, Vandenberghe M, Cremonesi JA, Ferri CG, Nizar K, Sridhar VB, Steed TC, Abashin M, Fainman Y, Masliah E, Djurovic S, Andreassen OA, Silva GA, Boas DA, Kleinfeld D, Buxton RB, Einevoll GT, Dale AM, Devor A. Cell type specificity of neurovascular coupling in cerebral cortex. Elife. 2016 05 31; 5. PMID: 27244241; PMCID: PMC4933561; DOI: 10.7554/eLife.14315;

Wang H, Akkin T, Magnain C, Wang R, Dubb J, Kostis WJ, Yaseen MA, Cramer A, Sakadžic S, Boas D. Polarization sensitive optical coherence microscopy for brain imaging. Opt Lett. 2016 May 15; 41(10):2213-6. PMID: 27176965; PMCID: PMC5357322

Bianciardi M, Toschi N, Polimeni JR, Evans KC, Bhat H, Keil B, Rosen BR, Boas DA, Wald LL. The pulsatility volume index: an indicator of cerebrovascular compliance based on fast magnetic resonance imaging of cardiac and respiratory pulsatility. Philos Trans A Math Phys Eng Sci. 2016 May 13; 374(2067). PMID: 27044992; PMCID: PMC4822444; DOI: 10.1098/rsta.2015.0184;

Li B, Lee J, Boas DA, Lesage F. Contribution of low- and high-flux capillaries to slow hemodynamic fluctuations in the cerebral cortex of mice. J Cereb Blood Flow Metab. 2016 Aug; 36(8):1351-6. PMID: 27165011; PMCID: PMC4976754; DOI: 10.1177/0271678X16649195;

Magnain C, Wang H, Sakadžic S, Fischl B, Boas DA. En face speckle reduction in optical coherence microscopy by frequency compounding. Opt Lett. 2016 May 01; 41(9):1925-8. PMID: 27128040; PMCID: PMC5350630

Becerra L, Aasted CM, Boas DA, George E, Yücel MA, Kussman BD, Kelsey P, Borsook D. Brain measures of nociception using near-infrared spectroscopy in patients undergoing routine screening colonoscopy. Pain. 2016 Apr; 157(4):840-848. PMID: 26645550; PMCID: PMC4794375; DOI: 10.1097/j.pain.0000000000000446;

Davis MA, Gagnon L, Boas DA, Dunn AK. Sensitivity of laser speckle contrast imaging to flow perturbations in the cortex. Biomed Opt Express. 2016 Mar 01; 7(3):759-75. PMID: 27231587; PMCID: PMC4866454; DOI: 10.1364/BOE.7.000759;

Zimmermann BB, Fang Q, Boas DA, Carp SA. Frequency domain near-infrared multiwavelength imager design using high-speed, direct analog-to-digital conversion. J Biomed Opt. 2016 Jan; 21(1):16010. PMID: 26813081; PMCID: PMC4726736; DOI: 10.1117/1.JBO.21.1.016010;

Yaseen MA, Srinivasan VJ, Gorczynska I, Fujimoto JG, Boas DA, Sakadžic S. Multimodal optical imaging system for in vivo investigation of cerebral oxygen delivery and energy metabolism. Biomed Opt Express. 2015 Dec 01; 6(12):4994-5007. PMID: 26713212; PMCID: PMC4679272; DOI: 10.1364/BOE.6.004994;

Lee J, Wu W, Boas DA. Early capillary flux homogenization in response to neural activation. J Cereb Blood Flow Metab. 2016 Feb; 36(2):375-80. PMID: 26661145; PMCID: PMC4759663; DOI: 10.1177/0271678X15605851;

Hayakawa K, Pham LD, Seo JH, Miyamoto N, Maki T, Terasaki Y, Sakadžic S, Boas D, van Leyen K, Waeber C, Kim KW, Arai K, Lo EH. CD200 restrains macrophage attack on oligodendrocyte precursors via toll-like receptor 4 downregulation. J Cereb Blood Flow Metab. 2016 Apr; 36(4):781-93. PMID: 26661156; PMCID: PMC4821018; DOI: 10.1177/0271678X15606148;

Yücel MA, Selb J, Aasted CM, Petkov MP, Becerra L, Borsook D, Boas DA. Short separation regression improves statistical significance and better localizes the hemodynamic response obtained by near-infrared spectroscopy for tasks with differing autonomic responses. Neurophotonics. 2015 Jul; 2(3):035005. PMID: 26835480; PMCID: PMC4717232; DOI: 10.1117/1.NPh.2.3.035005;

Deng B, Fradkin M, Rouet JM, Moore RH, Kopans DB, Boas DA, Lundqvist M, Fang Q. Characterizing breast lesions through robust multimodal data fusion using independent diffuse optical and x-ray breast imaging. J Biomed Opt. 2015 Aug; 20(8):80502. PMID: 26263413; PMCID: PMC4689098; DOI: 10.1117/1.JBO.20.8.080502;

Baek K, Shim WH, Jeong J, Radhakrishnan H, Rosen BR, Boas D, Franceschini M, Biswal BB, Kim YR. Layer-specific interhemispheric functional connectivity in the somatosensory cortex of rats: resting state electrophysiology and fMRI studies. Brain Struct Funct. 2016 06; 221(5):2801-15. PMID: 26077581; PMCID: PMC4681693; DOI: 10.1007/s00429-015-1073-0;

Deng B, Brooks DH, Boas DA, Lundqvist M, Fang Q. Characterization of structural-prior guided optical tomography using realistic breast models derived from dual-energy x-ray mammography. Biomed Opt Express. 2015 Jul 01; 6(7):2366-79. PMID: 26203367; PMCID: PMC4505695; DOI: 10.1364/BOE.6.002366;

Sakadžic S, Lee J, Boas DA, Ayata C. High-resolution in vivo optical imaging of stroke injury and repair. Brain Res. 2015 Oct 14; 1623:174-92. PMID: 25960347; PMCID: PMC4569527; DOI: 10.1016/j.brainres.2015.04.044;

Aasted CM, Yücel MA, Cooper RJ, Dubb J, Tsuzuki D, Becerra L, Petkov MP, Borsook D, Dan I, Boas DA. Anatomical guidance for functional near-infrared spectroscopy: AtlasViewer tutorial. Neurophotonics. 2015 Apr; 2(2):020801. PMID: 26157991; PMCID: PMC4478785; DOI: 10.1117/1.NPh.2.2.020801;

Selb J, Yücel MA, Phillip D, Schytz HW, Iversen HK, Vangel M, Ashina M, Boas DA. Effect of motion artifacts and their correction on near-infrared spectroscopy oscillation data: a study in healthy subjects and stroke patients. J Biomed Opt. 2015 May; 20(5):56011. PMID: 26018790; PMCID: PMC4445402; DOI: 10.1117/1.JBO.20.5.056011;

Boas D. Neurophotonics Pioneers and News. Neurophotonics. 2015 Apr; 2(2):020101. PMID: 26157988; PMCID: PMC4487644; DOI: 10.1117/1.NPh.2.2.020101;

Yücel MA, Aasted CM, Petkov MP, Borsook D, Boas DA, Becerra L. Specificity of hemodynamic brain responses to painful stimuli: a functional near-infrared spectroscopy study. Sci Rep. 2015 Mar 30; 5:9469. PMID: 25820289; PMCID: PMC4377554; DOI: 10.1038/srep09469;

Gagnon L, Sakadžic S, Lesage F, Mandeville ET, Fang Q, Yaseen MA, Boas DA. Multimodal reconstruction of microvascular-flow distributions using combined two-photon microscopy and Doppler optical coherence tomography. Neurophotonics. 2015 Jan; 2(1):015008. PMID: 26157987; PMCID: PMC4478873; DOI: 10.1117/1.NPh.2.1.015008;

von Bornstädt D, Houben T, Seidel JL, Zheng Y, Dilekoz E, Qin T, Sandow N, Kura S, Eikermann-Haerter K, Endres M, Boas DA, Moskowitz MA, Lo EH, Dreier JP, Woitzik J, Sakadžic S, Ayata C. Supply-demand mismatch transients in susceptible peri-infarct hot zones explain the origins of spreading injury depolarizations. Neuron. 2015 Mar 04; 85(5):1117-31. PMID: 25741731; PMCID: PMC4351476; DOI: 10.1016/j.neuron.2015.02.007;

Gagnon L, Sakadžic S, Lesage F, Musacchia JJ, Lefebvre J, Fang Q, Yücel MA, Evans KC, Mandeville ET, Cohen-Adad J, Polimeni JR, Yaseen MA, Lo EH, Greve DN, Buxton RB, Dale AM, Devor A, Boas DA. Quantifying the microvascular origin of BOLD-fMRI from first principles with two-photon microscopy and an oxygen-sensitive nanoprobe. J Neurosci. 2015 Feb 25; 35(8):3663-75. PMID: 25716864; PMCID: PMC4339366; DOI: 10.1523/JNEUROSCI.3555-14.2015;

Magnain C, Augustinack JC, Konukoglu E, Frosch MP, Sakadžic S, Varjabedian A, Garcia N, Wedeen VJ, Boas DA, Fischl B. Optical coherence tomography visualizes neurons in human entorhinal cortex. Neurophotonics. 2015 Feb 09; 2(1):015004. PMID: 25741528; PMCID: PMC4346095; DOI: 10.1117/1.NPh.2.1.015004;

Wijeakumar S, Spencer JP, Bohache K, Boas DA, Magnotta VA. Validating a new methodology for optical probe design and image registration in fNIRS studies. Neuroimage. 2015 Feb 01; 106:86-100. PMID: 25705757; PMCID: PMC4431570

Sakadžic S, Mandeville ET, Gagnon L, Musacchia JJ, Yaseen MA, Yucel MA, Lefebvre J, Lesage F, Dale AM, Eikermann-Haerter K, Ayata C, Srinivasan VJ, Lo EH, Devor A, Boas DA. Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue. Nat Commun. 2014 Dec 08; 5:5734. PMID: 25483924; PMCID: PMC4260810; DOI: 10.1038/ncomms6734;

Boas D. Neurophotonics Visibility, Indexing, and Impact. Neurophotonics. 2014 Oct; 1(2):020101. PMID: 26157975; PMCID: PMC4489345; DOI: 10.1117/1.NPh.1.2.020101;

Yücel MA, Evans KC, Selb J, Huppert TJ, Boas DA, Gagnon L. Validation of the hypercapnic calibrated fMRI method using DOT-fMRI fusion imaging. Neuroimage. 2014 Nov 15; 102 Pt 2:729-35. PMID: 25196509; PMCID: PMC4252607; DOI: 10.1016/j.neuroimage.2014.08.052;

Selb J, Boas DA, Chan ST, Evans KC, Buckley EM, Carp SA. Sensitivity of near-infrared spectroscopy and diffuse correlation spectroscopy to brain hemodynamics: simulations and experimental findings during hypercapnia. Neurophotonics. 2014 Jul; 1(1). PMID: 25453036; PMCID: PMC4247161; DOI: 10.1117/1.NPh.1.1.015005;

Devor A, Roe AW, Mahadevan-Jansen A, Boas DA. The BRAIN Initiative. Neurophotonics. 2014 Jul; 1(1):011001. PMID: 26157962; PMCID: PMC4489344; DOI: 10.1117/1.NPh.1.1.011001;

Boas D. Welcome to Neurophotonics. Neurophotonics. 2014 Jul; 1(1):010101. PMID: 26157961; PMCID: PMC4489348; DOI: 10.1117/1.NPh.1.1.010101;

Wang H, Zhu J, Reuter M, Vinke LN, Yendiki A, Boas DA, Fischl B, Akkin T. Cross-validation of serial optical coherence scanning and diffusion tensor imaging: a study on neural fiber maps in human medulla oblongata. Neuroimage. 2014 Oct 15; 100:395-404. PMID: 24954840; PMCID: PMC4142686; DOI: 10.1016/j.neuroimage.2014.06.032;

Wilcox T, Hawkins LB, Hirshkowitz A, Boas DA. Cortical activation to object shape and speed of motion during the first year. Neuroimage. 2014 Oct 01; 99:129-41. PMID: 24821531; PMCID: PMC4228933; DOI: 10.1016/j.neuroimage.2014.04.082;

Lee J, Jiang JY, Wu W, Lesage F, Boas DA. Statistical intensity variation analysis for rapid volumetric imaging of capillary network flux. Biomed Opt Express. 2014 Apr 01; 5(4):1160-72. PMID: 24761298; PMCID: PMC3986000; DOI: 10.1364/BOE.5.001160;

Yücel MA, Selb J, Cooper RJ, Boas DA. TARGETED PRINCIPLE COMPONENT ANALYSIS: A NEW MOTION ARTIFACT CORRECTION APPROACH FOR NEAR-INFRARED SPECTROSCOPY. J Innov Opt Health Sci. 2014 Mar 01; 7(2). PMID: 25360181; PMCID: PMC4211632; DOI: 10.1142/S1793545813500661;

Boas DA, Elwell CE, Ferrari M, Taga G. Twenty years of functional near-infrared spectroscopy: introduction for the special issue. Neuroimage. 2014 Jan 15; 85 Pt 1:1-5. PMID: 24321364; DOI: 10.1016/j.neuroimage.2013.11.033;

Selb J, Ogden TM, Dubb J, Fang Q, Boas DA. Comparison of a layered slab and an atlas head model for Monte Carlo fitting of time-domain near-infrared spectroscopy data of the adult head. J Biomed Opt. 2014 Jan; 19(1):16010. PMID: 24407503; PMCID: PMC3886581; DOI: 10.1117/1.JBO.19.1.016010;

Phillip D, Iversen HK, Schytz HW, Selb J, Boas DA, Ashina M. Altered Low Frequency Oscillations of Cortical Vessels in Patients with Cerebrovascular Occlusive Disease - A NIRS Study. Front Neurol. 2013; 4:204. PMID: 24379801; PMCID: PMC3864103; DOI: 10.3389/fneur.2013.00204;

Carp SA, Sajjadi AY, Wanyo CM, Fang Q, Specht MC, Schapira L, Moy B, Bardia A, Boas DA, Isakoff SJ. Hemodynamic signature of breast cancer under fractional mammographic compression using a dynamic diffuse optical tomography system. Biomed Opt Express. 2013; 4(12):2911-24. PMID: 24409390; PMCID: PMC3862147; DOI: 10.1364/BOE.4.002911;

Devor A, Bandettini PA, Boas DA, Bower JM, Buxton RB, Cohen LB, Dale AM, Einevoll GT, Fox PT, Franceschini MA, Friston KJ, Fujimoto JG, Geyer MA, Greenberg JH, Halgren E, Hämäläinen MS, Helmchen F, Hyman BT, Jasanoff A, Jernigan TL, Judd LL, Kim SG, Kleinfeld D, Kopell NJ, Kutas M, Kwong KK, Larkum ME, Lo EH, Magistretti PJ, Mandeville JB, Masliah E, Mitra PP, Mobley WC, Moskowitz MA, Nimmerjahn A, Reynolds JH, Rosen BR, Salzberg BM, Schaffer CB, Silva GA, So PT, Spitzer NC, Tootell RB, Van Essen DC, Vanduffel W, Vinogradov SA, Wald LL, Wang LV, Weber B, Yodh AG. The challenge of connecting the dots in the B.R.A.I.N. Neuron. 2013 Oct 16; 80(2):270-4.View Related Profiles.

Boas, David
Kopell, Nancy

PMID: 24139032; PMCID: PMC3864648; DOI: 10.1016/j.neuron.2013.09.008;

Magnain C, Augustinack JC, Reuter M, Wachinger C, Frosch MP, Ragan T, Akkin T, Wedeen VJ, Boas DA, Fischl B. Blockface histology with optical coherence tomography: a comparison with Nissl staining. Neuroimage. 2014 Jan 01; 84:524-33. PMID: 24041872; PMCID: PMC4315235; DOI: 10.1016/j.neuroimage.2013.08.072;

Lee J, Wu W, Lesage F, Boas DA. Multiple-capillary measurement of RBC speed, flux, and density with optical coherence tomography. J Cereb Blood Flow Metab. 2013 Nov; 33(11):1707-10. PMID: 24022621; PMCID: PMC3824190; DOI: 10.1038/jcbfm.2013.158;

Wilcox T, Hirshkowitz A, Hawkins L, Boas DA. The effect of color priming on infant brain and behavior. Neuroimage. 2014 Jan 15; 85 Pt 1:302-13. PMID: 24007805; PMCID: PMC3871198; DOI: 10.1016/j.neuroimage.2013.08.045;

Miyamoto N, Pham LD, Hayakawa K, Matsuzaki T, Seo JH, Magnain C, Ayata C, Kim KW, Boas D, Lo EH, Arai K. Age-related decline in oligodendrogenesis retards white matter repair in mice. Stroke. 2013 Sep; 44(9):2573-8. PMID: 23881957; PMCID: PMC3818687; DOI: 10.1161/STROKEAHA.113.001530;

Yücel MA, Selb J, Boas DA, Cash SS, Cooper RJ. Reducing motion artifacts for long-term clinical NIRS monitoring using collodion-fixed prism-based optical fibers. Neuroimage. 2014 Jan 15; 85 Pt 1:192-201. PMID: 23796546; PMCID: PMC3849205; DOI: 10.1016/j.neuroimage.2013.06.054;

Buss AT, Fox N, Boas DA, Spencer JP. Probing the early development of visual working memory capacity with functional near-infrared spectroscopy. Neuroimage. 2014 Jan 15; 85 Pt 1:314-25. PMID: 23707803; PMCID: PMC3859697; DOI: 10.1016/j.neuroimage.2013.05.034;

Augustinack JC, Magnain C, Reuter M, van der Kouwe AJ, Boas D, Fischl B. MRI parcellation of ex vivo medial temporal lobe. Neuroimage. 2014 Jun; 93 Pt 2:252-9. PMID: 23702414; PMCID: PMC3883990; DOI: 10.1016/j.neuroimage.2013.05.053;

Nizar K, Uhlirova H, Tian P, Saisan PA, Cheng Q, Reznichenko L, Weldy KL, Steed TC, Sridhar VB, MacDonald CL, Cui J, Gratiy SL, Sakadzic S, Boas DA, Beka TI, Einevoll GT, Chen J, Masliah E, Dale AM, Silva GA, Devor A. In vivo stimulus-induced vasodilation occurs without IP3 receptor activation and may precede astrocytic calcium increase. J Neurosci. 2013 May 08; 33(19):8411-22. PMID: 23658179; PMCID: PMC3712855; DOI: 10.1523/JNEUROSCI.3285-12.2013;

Brigadoi S, Ceccherini L, Cutini S, Scarpa F, Scatturin P, Selb J, Gagnon L, Boas DA, Cooper RJ. Motion artifacts in functional near-infrared spectroscopy: a comparison of motion correction techniques applied to real cognitive data. Neuroimage. 2014 Jan 15; 85 Pt 1:181-91. PMID: 23639260; PMCID: PMC3762942; DOI: 10.1016/j.neuroimage.2013.04.082;

Schytz HW, Jensen BE, Jennum P, Selb J, Boas DA, Ashina M. Low-frequency oscillations and vasoreactivity of cortical vessels in obstructive sleep apnea during wakefulness: a near infrared spectroscopy study. Sleep Med. 2013 May; 14(5):416-21. PMID: 23517585; PMCID: PMC6420812; DOI: 10.1016/j.sleep.2012.12.009;

Lee J, Radhakrishnan H, Wu W, Daneshmand A, Climov M, Ayata C, Boas DA. Quantitative imaging of cerebral blood flow velocity and intracellular motility using dynamic light scattering-optical coherence tomography. J Cereb Blood Flow Metab. 2013 Jun; 33(6):819-25.View Related Profiles.

Daneshmand, Ali
Boas, David

PMID: 23403378; PMCID: PMC3677104; DOI: 10.1038/jcbfm.2013.20;

Gagnon L, Yücel MA, Boas DA, Cooper RJ. Further improvement in reducing superficial contamination in NIRS using double short separation measurements. Neuroimage. 2014 Jan 15; 85 Pt 1:127-35. PMID: 23403181; PMCID: PMC3665655; DOI: 10.1016/j.neuroimage.2013.01.073;

Roche-Labarbe N, Fenoglio A, Radhakrishnan H, Kocienski-Filip M, Carp SA, Dubb J, Boas DA, Grant PE, Franceschini MA. Somatosensory evoked changes in cerebral oxygen consumption measured non-invasively in premature neonates. Neuroimage. 2014 Jan 15; 85 Pt 1:279-86. PMID: 23370052; PMCID: PMC3686986; DOI: 10.1016/j.neuroimage.2013.01.035;

Yaseen MA, Sakadžic S, Wu W, Becker W, Kasischke KA, Boas DA. In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH. Biomed Opt Express. 2013 Feb 01; 4(2):307-21. PMID: 23412419; PMCID: PMC3567717; DOI: 10.1364/BOE.4.000307;

Cooper RJ, Selb J, Gagnon L, Phillip D, Schytz HW, Iversen HK, Ashina M, Boas DA. A systematic comparison of motion artifact correction techniques for functional near-infrared spectroscopy. Front Neurosci. 2012; 6:147. PMID: 23087603; PMCID: PMC3468891; DOI: 10.3389/fnins.2012.00147;

Lee J, Wu W, Jiang JY, Zhu B, Boas DA. Dynamic light scattering optical coherence tomography. Opt Express. 2012 Sep 24; 20(20):22262-77. PMID: 23037374; PMCID: PMC3601731

Phillip D, Schytz HW, Selb J, Payne S, Iversen HK, Skovgaard LT, Boas DA, Ashina M. Low frequency oscillations in cephalic vessels assessed by near infrared spectroscopy. Eur J Clin Invest. 2012 Nov; 42(11):1180-8. PMID: 22897146; PMCID: PMC3730271; DOI: 10.1111/j.1365-2362.2012.02704.x;

Wilcox T, Stubbs J, Hirshkowitz A, Boas DA. Functional activation of the infant cortex during object processing. Neuroimage. 2012 Sep; 62(3):1833-40. PMID: 22634218; PMCID: PMC3457789; DOI: 10.1016/j.neuroimage.2012.05.039;

Cooper RJ, Caffini M, Dubb J, Fang Q, Custo A, Tsuzuki D, Fischl B, Wells W, Dan I, Boas DA. Validating atlas-guided DOT: a comparison of diffuse optical tomography informed by atlas and subject-specific anatomies. Neuroimage. 2012 Sep; 62(3):1999-2006. PMID: 22634215; PMCID: PMC3408558; DOI: 10.1016/j.neuroimage.2012.05.031;

Yücel MA, Huppert TJ, Boas DA, Gagnon L. Calibrating the BOLD signal during a motor task using an extended fusion model incorporating DOT, BOLD and ASL data. Neuroimage. 2012 Jul 16; 61(4):1268-76. PMID: 22546318; PMCID: PMC3376222; DOI: 10.1016/j.neuroimage.2012.04.036;

Schytz HW, Hansen JM, Phillip D, Selb J, Boas DA, Ashina M. Nitric oxide modulation of low-frequency oscillations in cortical vessels in FHM--a NIRS study. Headache. 2012 Jul-Aug; 52(7):1146-54. PMID: 22352839; PMCID: PMC3730264; DOI: 10.1111/j.1526-4610.2012.02098.x;

Devor A, Sakadžic S, Srinivasan VJ, Yaseen MA, Nizar K, Saisan PA, Tian P, Dale AM, Vinogradov SA, Franceschini MA, Boas DA. Frontiers in optical imaging of cerebral blood flow and metabolism. J Cereb Blood Flow Metab. 2012 Jul; 32(7):1259-76. PMID: 22252238; PMCID: PMC3390808; DOI: 10.1038/jcbfm.2011.195;

Devor A, Boas D. Neurovascular imaging. Front Neuroenergetics. 2012; 4:1. PMID: 22279435; PMCID: PMC3260454; DOI: 10.3389/fnene.2012.00001;

Zimmermann BB, Roche-Labarbe N, Surova A, Boas DA, Wolf M, Grant PE, Franceschini MA. The confounding effect of systemic physiology on the hemodynamic response in newborns. Adv Exp Med Biol. 2012; 737:103-9. PMID: 22259089; PMCID: PMC3386795; DOI: 10.1007/978-1-4614-1566-4_16;

Lee J, Boas DA. Frequency-domain measurement of neuronal activity using dynamic optical coherence tomography. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:2643-6. PMID: 23366468; PMCID: PMC3733238; DOI: 10.1109/EMBC.2012.6346507;

Boas DA, Franceschini MA. Haemoglobin oxygen saturation as a biomarker: the problem and a solution. Philos Trans A Math Phys Eng Sci. 2011 Nov 28; 369(1955):4407-24. PMID: 22006898; PMCID: PMC3263786; DOI: 10.1098/rsta.2011.0250;

Cooper RJ, Gagnon L, Goldenholz DM, Boas DA, Greve DN. The utility of near-infrared spectroscopy in the regression of low-frequency physiological noise from functional magnetic resonance imaging data. Neuroimage. 2012 Feb 15; 59(4):3128-38. PMID: 22119653; PMCID: PMC3288700; DOI: 10.1016/j.neuroimage.2011.11.028;

Lee J, Srinivasan V, Radhakrishnan H, Boas DA. Motion correction for phase-resolved dynamic optical coherence tomography imaging of rodent cerebral cortex. Opt Express. 2011 Oct 24; 19(22):21258-70. PMID: 22108978; PMCID: PMC3386793

Gagnon L, Yücel MA, Dehaes M, Cooper RJ, Perdue KL, Selb J, Huppert TJ, Hoge RD, Boas DA. Quantification of the cortical contribution to the NIRS signal over the motor cortex using concurrent NIRS-fMRI measurements. Neuroimage. 2012 Feb 15; 59(4):3933-40. PMID: 22036999; PMCID: PMC3279595; DOI: 10.1016/j.neuroimage.2011.10.054;

Yuzawa I, Sakadžic S, Srinivasan VJ, Shin HK, Eikermann-Haerter K, Boas DA, Ayata C. Cortical spreading depression impairs oxygen delivery and metabolism in mice. J Cereb Blood Flow Metab. 2012 Feb; 32(2):376-86. PMID: 22008729; PMCID: PMC3272607; DOI: 10.1038/jcbfm.2011.148;

Baraghis E, Devor A, Fang Q, Srinivasan VJ, Wu W, Lesage F, Ayata C, Kasischke KA, Boas DA, Sakadzic S. Two-photon microscopy of cortical NADH fluorescence intensity changes: correcting contamination from the hemodynamic response. J Biomed Opt. 2011 Oct; 16(10):106003. PMID: 22029350; PMCID: PMC3206923; DOI: 10.1117/1.3633339;

Devor A, Sakadzic S, Saisan PA, Yaseen MA, Roussakis E, Srinivasan VJ, Vinogradov SA, Rosen BR, Buxton RB, Dale AM, Boas DA. "Overshoot" of O2 is required to maintain baseline tissue oxygenation at locations distal to blood vessels. J Neurosci. 2011 Sep 21; 31(38):13676-81. PMID: 21940458; PMCID: PMC3188944; DOI: 10.1523/JNEUROSCI.1968-11.2011;

Gagnon L, Cooper RJ, Yücel MA, Perdue KL, Greve DN, Boas DA. Short separation channel location impacts the performance of short channel regression in NIRS. Neuroimage. 2012 Feb 01; 59(3):2518-28. PMID: 21945793; PMCID: PMC3254723; DOI: 10.1016/j.neuroimage.2011.08.095;

Carp SA, Roche-Labarbe N, Franceschini MA, Srinivasan VJ, Sakadžic S, Boas DA. Due to intravascular multiple sequential scattering, Diffuse Correlation Spectroscopy of tissue primarily measures relative red blood cell motion within vessels. Biomed Opt Express. 2011 Jul 01; 2(7):2047-54. PMID: 21750779; PMCID: PMC3130588; DOI: 10.1364/BOE.2.002047;

Lee J, Boas DA, Kim SJ. Multiphysics neuron model for cellular volume dynamics. IEEE Trans Biomed Eng. 2011 Oct; 58(10):3000-3. PMID: 21659016; PMCID: PMC3752667; DOI: 10.1109/TBME.2011.2159217;

Mazhar A, Cuccia DJ, Rice TB, Carp SA, Durkin AJ, Boas DA, Choi B, Tromberg BJ. Laser speckle imaging in the spatial frequency domain. Biomed Opt Express. 2011 Jun 01; 2(6):1553-63. PMID: 21698018; PMCID: PMC3114223; DOI: 10.1364/BOE.2.001553;

Sakadžic S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Wu W, Devor A, Lo EH, Vinogradov SA, Boas DA. Cerebral blood oxygenation measurement based on oxygen-dependent quenching of phosphorescence. J Vis Exp. 2011 May 04; (51). PMID: 21587157; PMCID: PMC3197095; DOI: 10.3791/1694;

Gagnon L, Perdue K, Greve DN, Goldenholz D, Kaskhedikar G, Boas DA. Improved recovery of the hemodynamic response in diffuse optical imaging using short optode separations and state-space modeling. Neuroimage. 2011 Jun 01; 56(3):1362-71. PMID: 21385616; PMCID: PMC3085546; DOI: 10.1016/j.neuroimage.2011.03.001;

Srinivasan VJ, Atochin DN, Radhakrishnan H, Jiang JY, Ruvinskaya S, Wu W, Barry S, Cable AE, Ayata C, Huang PL, Boas DA. Optical coherence tomography for the quantitative study of cerebrovascular physiology. J Cereb Blood Flow Metab. 2011 Jun; 31(6):1339-45. PMID: 21364599; PMCID: PMC3130321; DOI: 10.1038/jcbfm.2011.19;

Dehaes M, Grant PE, Sliva DD, Roche-Labarbe N, Pienaar R, Boas DA, Franceschini MA, Selb J. Assessment of the frequency-domain multi-distance method to evaluate the brain optical properties: Monte Carlo simulations from neonate to adult. Biomed Opt Express. 2011 Feb 11; 2(3):552-67. PMID: 21412461; PMCID: PMC3047361; DOI: 10.1364/BOE.2.000552;

Tian P, Devor A, Sakadzic S, Dale AM, Boas DA. Monte Carlo simulation of the spatial resolution and depth sensitivity of two-dimensional optical imaging of the brain. J Biomed Opt. 2011 Jan-Feb; 16(1):016006. PMID: 21280912; PMCID: PMC3041814; DOI: 10.1117/1.3533263;

Yaseen MA, Srinivasan VJ, Sakadžic S, Radhakrishnan H, Gorczynska I, Wu W, Fujimoto JG, Boas DA. Microvascular oxygen tension and flow measurements in rodent cerebral cortex during baseline conditions and functional activation. J Cereb Blood Flow Metab. 2011 Apr; 31(4):1051-63. PMID: 21179069; PMCID: PMC3070982; DOI: 10.1038/jcbfm.2010.227;

Radhakrishnan H, Wu W, Boas D, Franceschini MA. Study of neurovascular coupling by modulating neuronal activity with GABA. Brain Res. 2011 Feb 04; 1372:1-12. PMID: 21145313; PMCID: PMC3037022; DOI: 10.1016/j.brainres.2010.11.082;

Fang Q, Selb J, Carp SA, Boverman G, Miller EL, Brooks DH, Moore RH, Kopans DB, Boas DA. Combined optical and X-ray tomosynthesis breast imaging. Radiology. 2011 Jan; 258(1):89-97. PMID: 21062924; PMCID: PMC3009384; DOI: 10.1148/radiol.10082176;

Schytz HW, Hansson A, Phillip D, Selb J, Boas DA, Iversen HK, Ashina M. Spontaneous low-frequency oscillations in cerebral vessels: applications in carotid artery disease and ischemic stroke. J Stroke Cerebrovasc Dis. 2010 Nov-Dec; 19(6):465-74. PMID: 20864356; PMCID: PMC3752675; DOI: 10.1016/j.jstrokecerebrovasdis.2010.06.001;

Carp SA, Dai GP, Boas DA, Franceschini MA, Kim YR. Validation of diffuse correlation spectroscopy measurements of rodent cerebral blood flow with simultaneous arterial spin labeling MRI; towards MRI-optical continuous cerebral metabolic monitoring. Biomed Opt Express. 2010 Aug 10; 1(2):553-565. PMID: 21258489; PMCID: PMC3017992; DOI: 10.1364/BOE.1.000553;

Tian P, Teng IC, May LD, Kurz R, Lu K, Scadeng M, Hillman EM, De Crespigny AJ, D'Arceuil HE, Mandeville JB, Marota JJ, Rosen BR, Liu TT, Boas DA, Buxton RB, Dale AM, Devor A. Cortical depth-specific microvascular dilation underlies laminar differences in blood oxygenation level-dependent functional MRI signal. Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34):15246-51. PMID: 20696904; PMCID: PMC2930564; DOI: 10.1073/pnas.1006735107;

Sakadzic S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Devor A, Lo EH, Vinogradov SA, Boas DA. Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue. Nat Methods. 2010 Sep; 7(9):755-9. PMID: 20693997; PMCID: PMC2932799; DOI: 10.1038/nmeth.1490;

Chen HC, Vaid J, Boas DA, Bortfeld H. Examining the phonological neighborhood density effect using near infrared spectroscopy. Hum Brain Mapp. 2011 Sep; 32(9):1363-70. PMID: 20690126; PMCID: PMC3039710; DOI: 10.1002/hbm.21115;

Mesquita RC, Franceschini MA, Boas DA. Resting state functional connectivity of the whole head with near-infrared spectroscopy. Biomed Opt Express. 2010 Jul 28; 1(1):324-336. PMID: 21258470; PMCID: PMC3005169; DOI: 10.1364/BOE.1.000324;

Fang Q, Moore RH, Kopans DB, Boas DA. Compositional-prior-guided image reconstruction algorithm for multi-modality imaging. Biomed Opt Express. 2010 Jul 16; 1(1):223-235. PMID: 21258460; PMCID: PMC3005170; DOI: 10.1364/boe.1.000223;

Wilcox T, Haslup JA, Boas DA. Dissociation of processing of featural and spatiotemporal information in the infant cortex. Neuroimage. 2010 Dec; 53(4):1256-63. PMID: 20603218; PMCID: PMC2950116; DOI: 10.1016/j.neuroimage.2010.06.064;

Raymond SB, Boas DA, Bacskai BJ, Kumar AT. Lifetime-based tomographic multiplexing. J Biomed Opt. 2010 Jul-Aug; 15(4):046011. PMID: 20799813; PMCID: PMC2929260; DOI: 10.1117/1.3469797;

Hyde DC, Boas DA, Blair C, Carey S. Near-infrared spectroscopy shows right parietal specialization for number in pre-verbal infants. Neuroimage. 2010 Nov 01; 53(2):647-52. PMID: 20561591; PMCID: PMC2930081; DOI: 10.1016/j.neuroimage.2010.06.030;

Franceschini MA, Radhakrishnan H, Thakur K, Wu W, Ruvinskaya S, Carp S, Boas DA. The effect of different anesthetics on neurovascular coupling. Neuroimage. 2010 Jul 15; 51(4):1367-77. PMID: 20350606; PMCID: PMC2879067; DOI: 10.1016/j.neuroimage.2010.03.060;

Roche-Labarbe N, Carp SA, Surova A, Patel M, Boas DA, Grant PE, Franceschini MA. Noninvasive optical measures of CBV, StO(2), CBF index, and rCMRO(2) in human premature neonates' brains in the first six weeks of life. Hum Brain Mapp. 2010 Mar; 31(3):341-52. PMID: 19650140; PMCID: PMC2826558; DOI: 10.1002/hbm.20868;

Srinivasan VJ, Sakadzic S, Gorczynska I, Ruvinskaya S, Wu W, Fujimoto JG, Boas DA. Quantitative cerebral blood flow with optical coherence tomography. Opt Express. 2010 Feb 01; 18(3):2477-94. PMID: 20174075; PMCID: PMC2837842; DOI: 10.1364/OE.18.002477;

Sukhotinsky I, Yaseen MA, Sakadzic S, Ruvinskaya S, Sims JR, Boas DA, Moskowitz MA, Ayata C. Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range. J Cereb Blood Flow Metab. 2010 Jun; 30(6):1168-77. PMID: 20087371; PMCID: PMC2921789; DOI: 10.1038/jcbfm.2009.285;

Srinivasan VJ, Jiang JY, Yaseen MA, Radhakrishnan H, Wu W, Barry S, Cable AE, Boas DA. Rapid volumetric angiography of cortical microvasculature with optical coherence tomography. Opt Lett. 2010 Jan 01; 35(1):43-5. PMID: 20664667; PMCID: PMC2912612; DOI: 10.1364/OL.35.000043;

Boas DA, Dunn AK. Laser speckle contrast imaging in biomedical optics. J Biomed Opt. 2010 Jan-Feb; 15(1):011109. PMID: 20210435; PMCID: PMC2816990; DOI: 10.1117/1.3285504;

Yaseen MA, Srinivasan VJ, Sakadzic S, Wu W, Ruvinskaya S, Vinogradov SA, Boas DA. Optical monitoring of oxygen tension in cortical microvessels with confocal microscopy. Opt Express. 2009 Dec 07; 17(25):22341-50. PMID: 20052157; PMCID: PMC2857779; DOI: 10.1364/OE.17.022341;

Becerra L, Harris W, Grant M, George E, Boas D, Borsook D. Diffuse optical tomography activation in the somatosensory cortex: specific activation by painful vs. non-painful thermal stimuli. PLoS One. 2009 Nov 24; 4(11):e8016. PMID: 19956637; PMCID: PMC2778627; DOI: 10.1371/journal.pone.0008016;

Yücel MA, Devor A, Akin A, Boas DA. The Possible Role of CO(2) in Producing A Post-Stimulus CBF and BOLD Undershoot. Front Neuroenergetics. 2009; 1:7. PMID: 20027233; PMCID: PMC2795469; DOI: 10.3389/neuro.14.007.2009;

Fang Q, Boas DA. Monte Carlo simulation of photon migration in 3D turbid media accelerated by graphics processing units. Opt Express. 2009 Oct 26; 17(22):20178-90. PMID: 19997242; PMCID: PMC2863034; DOI: 10.1364/OE.17.020178;

Srinivasan VJ, Sakadzic S, Gorczynska I, Ruvinskaya S, Wu W, Fujimoto JG, Boas DA. Depth-resolved microscopy of cortical hemodynamics with optical coherence tomography. Opt Lett. 2009 Oct 15; 34(20):3086-8. PMID: 19838234; PMCID: PMC2778254; DOI: 10.1364/OL.34.003086;

Raymond SB, Kumar AT, Boas DA, Bacskai BJ. Optimal parameters for near infrared fluorescence imaging of amyloid plaques in Alzheimer's disease mouse models. Phys Med Biol. 2009 Oct 21; 54(20):6201-16. PMID: 19794239; PMCID: PMC3290001; DOI: 10.1088/0031-9155/54/20/011;

Boas DA, Payne SJ. Comment on 'Estimating a modified Grubb's exponent in healthy human brains with near infrared spectroscopy and transcranial Doppler'. Physiol Meas. 2009 Oct; 30(10):L9-L11; author reply L13-L14. PMID: 19767672; PMCID: PMC6487489; DOI: 10.1088/0967-3334/30/10/L01;

Muehlschlegel S, Selb J, Patel M, Diamond SG, Franceschini MA, Sorensen AG, Boas DA, Schwamm LH. Feasibility of NIRS in the neurointensive care unit: a pilot study in stroke using physiological oscillations. Neurocrit Care. 2009; 11(2):288-95. PMID: 19649749; PMCID: PMC2782535; DOI: 10.1007/s12028-009-9254-4;

Custo A, Boas DA, Tsuzuki D, Dan I, Mesquita R, Fischl B, Grimson WE, Wells W. Anatomical atlas-guided diffuse optical tomography of brain activation. Neuroimage. 2010 Jan 01; 49(1):561-7. PMID: 19643185; PMCID: PMC2858333; DOI: 10.1016/j.neuroimage.2009.07.033;

Payne SJ, Selb J, Boas DA. Effects of autoregulation and CO2 reactivity on cerebral oxygen transport. Ann Biomed Eng. 2009 Nov; 37(11):2288-98. PMID: 19629692; PMCID: PMC2800826; DOI: 10.1007/s10439-009-9763-5;

Grant PE, Roche-Labarbe N, Surova A, Themelis G, Selb J, Warren EK, Krishnamoorthy KS, Boas DA, Franceschini MA. Increased cerebral blood volume and oxygen consumption in neonatal brain injury. J Cereb Blood Flow Metab. 2009 Oct; 29(10):1704-13. PMID: 19675563; PMCID: PMC2762197; DOI: 10.1038/jcbfm.2009.90;

Kumar AT, Chung E, Raymond SB, van de Water JA, Shah K, Fukumura D, Jain RK, Bacskai BJ, Boas DA. Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. Opt Lett. 2009 Jul 01; 34(13):2066-8. PMID: 19572001; PMCID: PMC2872111

Huppert TJ, Jones PB, Devor A, Dunn AK, Teng IC, Dale AM, Boas DA. Sensitivity of neural-hemodynamic coupling to alterations in cerebral blood flow during hypercapnia. J Biomed Opt. 2009 Jul-Aug; 14(4):044038. PMID: 19725749; PMCID: PMC2774124; DOI: 10.1117/1.3210779;

Lebedev AY, Cheprakov AV, Sakadzic S, Boas DA, Wilson DF, Vinogradov SA. Dendritic phosphorescent probes for oxygen imaging in biological systems. ACS Appl Mater Interfaces. 2009 Jun; 1(6):1292-304. PMID: 20072726; PMCID: PMC2805241; DOI: 10.1021/am9001698;

Diamond SG, Perdue KL, Boas DA. A cerebrovascular response model for functional neuroimaging including dynamic cerebral autoregulation. Math Biosci. 2009 Aug; 220(2):102-17. PMID: 19442671; PMCID: PMC2720139; DOI: 10.1016/j.mbs.2009.05.002;

Huppert TJ, Allen MS, Diamond SG, Boas DA. Estimating cerebral oxygen metabolism from fMRI with a dynamic multicompartment Windkessel model. Hum Brain Mapp. 2009 May; 30(5):1548-67. PMID: 18649348; PMCID: PMC2670946; DOI: 10.1002/hbm.20628;

Schytz HW, Wienecke T, Jensen LT, Selb J, Boas DA, Ashina M. Changes in cerebral blood flow after acetazolamide: an experimental study comparing near-infrared spectroscopy and SPECT. Eur J Neurol. 2009 Apr; 16(4):461-7. PMID: 19236469; PMCID: PMC2782727; DOI: 10.1111/j.1468-1331.2008.02398.x;

Sakadzic S, Yuan S, Dilekoz E, Ruvinskaya S, Vinogradov SA, Ayata C, Boas DA. Simultaneous imaging of cerebral partial pressure of oxygen and blood flow during functional activation and cortical spreading depression. Appl Opt. 2009 Apr 01; 48(10):D169-77. PMID: 19340106; PMCID: PMC2692697

Huppert TJ, Diamond SG, Franceschini MA, Boas DA. HomER: a review of time-series analysis methods for near-infrared spectroscopy of the brain. Appl Opt. 2009 Apr 01; 48(10):D280-98. PMID: 19340120; PMCID: PMC2761652

Ou W, Nissilä I, Radhakrishnan H, Boas DA, Hämäläinen MS, Franceschini MA. Study of neurovascular coupling in humans via simultaneous magnetoencephalography and diffuse optical imaging acquisition. Neuroimage. 2009 Jul 01; 46(3):624-32. PMID: 19286463; PMCID: PMC2848457; DOI: 10.1016/j.neuroimage.2009.03.008;

Keller CJ, Cash SS, Narayanan S, Wang C, Kuzniecky R, Carlson C, Devinsky O, Thesen T, Doyle W, Sassaroli A, Boas DA, Ulbert I, Halgren E. Intracranial microprobe for evaluating neuro-hemodynamic coupling in unanesthetized human neocortex. J Neurosci Methods. 2009 May 15; 179(2):208-18. PMID: 19428529; PMCID: PMC2680793; DOI: 10.1016/j.jneumeth.2009.01.036;

Fang Q, Carp SA, Selb J, Boverman G, Zhang Q, Kopans DB, Moore RH, Miller EL, Brooks DH, Boas DA. Combined optical imaging and mammography of the healthy breast: optical contrast derived from breast structure and compression. IEEE Trans Med Imaging. 2009 Jan; 28(1):30-42. PMID: 19116186; PMCID: PMC2642986; DOI: 10.1109/TMI.2008.925082;

Bortfeld H, Fava E, Boas DA. Identifying cortical lateralization of speech processing in infants using near-infrared spectroscopy. Dev Neuropsychol. 2009; 34(1):52-65. PMID: 19142766; PMCID: PMC2981820; DOI: 10.1080/87565640802564481;

Devor A, Hillman EM, Tian P, Waeber C, Teng IC, Ruvinskaya L, Shalinsky MH, Zhu H, Haslinger RH, Narayanan SN, Ulbert I, Dunn AK, Lo EH, Rosen BR, Dale AM, Kleinfeld D, Boas DA. Stimulus-induced changes in blood flow and 2-deoxyglucose uptake dissociate in ipsilateral somatosensory cortex. J Neurosci. 2008 Dec 31; 28(53):14347-57. PMID: 19118167; PMCID: PMC2655308; DOI: 10.1523/JNEUROSCI.4307-08.2008;

Radhakrishnan H, Vanduffel W, Deng HP, Ekstrom L, Boas DA, Franceschini MA. Fast optical signal not detected in awake behaving monkeys. Neuroimage. 2009 Apr 01; 45(2):410-9. PMID: 19150500; PMCID: PMC2648855; DOI: 10.1016/j.neuroimage.2008.12.014;

Mesquita RC, Huppert TJ, Boas DA. Exploring neuro-vascular and neuro-metabolic coupling in rat somatosensory cortex. Phys Med Biol. 2009 Jan 21; 54(2):175-85. PMID: 19088392; PMCID: PMC2637347; DOI: 10.1088/0031-9155/54/2/001;

Chen Y, Aguirre AD, Ruvinskaya L, Devor A, Boas DA, Fujimoto JG. Optical coherence tomography (OCT) reveals depth-resolved dynamics during functional brain activation. J Neurosci Methods. 2009 Mar 30; 178(1):162-73. PMID: 19121336; PMCID: PMC3004397; DOI: 10.1016/j.jneumeth.2008.11.026;

Sakadzic S, Demirbas U, Mempel TR, Moore A, Ruvinskaya S, Boas DA, Sennaroglu A, Kaertner FX, Fujimoto JG. Multi-photon microscopy with a low-cost and highly efficient Cr:LiCAF laser. Opt Express. 2008 Dec 08; 16(25):20848-63. PMID: 19065223; PMCID: PMC2689708; DOI: 10.1364/oe.16.020848;

Wilcox T, Bortfeld H, Woods R, Wruck E, Armstrong J, Boas D. Hemodynamic changes in the infant cortex during the processing of featural and spatiotemporal information. Neuropsychologia. 2009 Feb; 47(3):657-62. PMID: 19071143; PMCID: PMC2705971; DOI: 10.1016/j.neuropsychologia.2008.11.014;

Fang Q, Sakadzic S, Ruvinskaya L, Devor A, Dale AM, Boas DA. Oxygen advection and diffusion in a three- dimensional vascular anatomical network. Opt Express. 2008 Oct 27; 16(22):17530-41. PMID: 18958033; PMCID: PMC2584207; DOI: 10.1364/oe.16.17530;

Carp SA, Selb J, Fang Q, Moore R, Kopans DB, Rafferty E, Boas DA. Dynamic functional and mechanical response of breast tissue to compression. Opt Express. 2008 Sep 29; 16(20):16064-78. PMID: 18825246; PMCID: PMC2650732; DOI: 10.1364/oe.16.016064;

Gagnon L, Gauthier C, Hoge RD, Lesage F, Selb J, Boas DA. Double-layer estimation of intra- and extracerebral hemoglobin concentration with a time-resolved system. J Biomed Opt. 2008 Sep-Oct; 13(5):054019. PMID: 19021399; PMCID: PMC2718835; DOI: 10.1117/1.2982524;

Huppert TJ, Diamond SG, Boas DA. Direct estimation of evoked hemoglobin changes by multimodality fusion imaging. J Biomed Opt. 2008 Sep-Oct; 13(5):054031. PMID: 19021411; PMCID: PMC2718838; DOI: 10.1117/1.2976432;

Kumar AT, Raymond SB, Dunn AK, Bacskai BJ, Boas DA. A time domain fluorescence tomography system for small animal imaging. IEEE Trans Med Imaging. 2008 Aug; 27(8):1152-63. PMID: 18672432; PMCID: PMC2920137; DOI: 10.1109/TMI.2008.918341;

Jones PB, Shin HK, Boas DA, Hyman BT, Moskowitz MA, Ayata C, Dunn AK. Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia. J Biomed Opt. 2008 Jul-Aug; 13(4):044007. PMID: 19021335; PMCID: PMC2790046; DOI: 10.1117/1.2950312;

Tromberg BJ, Pogue BW, Paulsen KD, Yodh AG, Boas DA, Cerussi AE. Assessing the future of diffuse optical imaging technologies for breast cancer management. Med Phys. 2008 Jun; 35(6):2443-51. PMID: 18649477; PMCID: PMC2809725; DOI: 10.1118/1.2919078;

Boverman G, Miller EL, Brooks DH, Isaacson D, Fang Q, Boas DA. Estimation and statistical bounds for three-dimensional polar shapes in diffuse optical tomography. IEEE Trans Med Imaging. 2008 Jun; 27(6):752-65. PMID: 18541483; PMCID: PMC2591024; DOI: 10.1109/TMI.2007.911492;

Wilcox T, Bortfeld H, Woods R, Wruck E, Boas DA. Hemodynamic response to featural changes in the occipital and inferior temporal cortex in infants: a preliminary methodological exploration. Dev Sci. 2008 May; 11(3):361-70. PMID: 18466370; PMCID: PMC2584206; DOI: 10.1111/j.1467-7687.2008.00681.x;

Franceschini MA, Nissilä I, Wu W, Diamond SG, Bonmassar G, Boas DA. Coupling between somatosensory evoked potentials and hemodynamic response in the rat. Neuroimage. 2008 Jun; 41(2):189-203. PMID: 18420425; PMCID: PMC2486435; DOI: 10.1016/j.neuroimage.2008.02.061;

Shin HK, Nishimura M, Jones PB, Ay H, Boas DA, Moskowitz MA, Ayata C. Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia. Stroke. 2008 May; 39(5):1548-55. PMID: 18340095; PMCID: PMC3023416; DOI: 10.1161/STROKEAHA.107.499483;

Kumar AT, Raymond SB, Bacskai BJ, Boas DA. Comparison of frequency-domain and time-domain fluorescence lifetime tomography. Opt Lett. 2008 Mar 01; 33(5):470-2. PMID: 18311295; PMCID: PMC2913597

Becerra L, Harris W, Joseph D, Huppert T, Boas DA, Borsook D. Diffuse optical tomography of pain and tactile stimulation: activation in cortical sensory and emotional systems. Neuroimage. 2008 Jun; 41(2):252-9. PMID: 18394924; PMCID: PMC2728450; DOI: 10.1016/j.neuroimage.2008.01.047;

Boas DA, Jones SR, Devor A, Huppert TJ, Dale AM. A vascular anatomical network model of the spatio-temporal response to brain activation. Neuroimage. 2008 Apr 15; 40(3):1116-29. PMID: 18289880; PMCID: PMC2577617; DOI: 10.1016/j.neuroimage.2007.12.061;

Selb J, Dale AM, Boas DA. Linear 3D reconstruction of time-domain diffuse optical imaging differential data: improved depth localization and lateral resolution. Opt Express. 2007 Dec 10; 15(25):16400-12. PMID: 19550930; PMCID: PMC3023417; DOI: 10.1364/oe.15.016400;

Chen HC, Vaid J, Bortfeld H, Boas DA. Optical imaging of phonological processing in two distinct orthographies. Exp Brain Res. 2008 Jan; 184(3):427-33. PMID: 17999056; PMCID: PMC2981147; DOI: 10.1007/s00221-007-1200-0;

Boverman G, Fang Q, Carp SA, Miller EL, Brooks DH, Selb J, Moore RH, Kopans DB, Boas DA. Spatio-temporal imaging of the hemoglobin in the compressed breast with diffuse optical tomography. Phys Med Biol. 2007 Jun 21; 52(12):3619-41. PMID: 17664563

Schweiger M, Nissilä I, Boas DA, Arridge SR. Image reconstruction in optical tomography in the presence of coupling errors. Appl Opt. 2007 May 10; 46(14):2743-56. PMID: 17446924

Franceschini MA, Thaker S, Themelis G, Krishnamoorthy KK, Bortfeld H, Diamond SG, Boas DA, Arvin K, Grant PE. Assessment of infant brain development with frequency-domain near-infrared spectroscopy. Pediatr Res. 2007 May; 61(5 Pt 1):546-51. PMID: 17413855; PMCID: PMC2637818; DOI: 10.1203/pdr.0b013e318045be99;

Shin HK, Dunn AK, Jones PB, Boas DA, Lo EH, Moskowitz MA, Ayata C. Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia. Brain. 2007 Jun; 130(Pt 6):1631-42. PMID: 17468117; PMCID: PMC3023418; DOI: 10.1093/brain/awm071;

Devor A, Tian P, Nishimura N, Teng IC, Hillman EM, Narayanan SN, Ulbert I, Boas DA, Kleinfeld D, Dale AM. Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative blood oxygenation level-dependent signal. J Neurosci. 2007 Apr 18; 27(16):4452-9. PMID: 17442830; PMCID: PMC2680207; DOI: 10.1523/JNEUROSCI.0134-07.2007;

Ma G, Delorme JF, Gallant P, Boas DA. Comparison of simplified Monte Carlo simulation and diffusion approximation for the fluorescence signal from phantoms with typical mouse tissue optical properties. Appl Opt. 2007 Apr 01; 46(10):1686-92. PMID: 17356611

Hillman EM, Devor A, Bouchard MB, Dunn AK, Krauss GW, Skoch J, Bacskai BJ, Dale AM, Boas DA. Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation. Neuroimage. 2007 Mar; 35(1):89-104. PMID: 17222567; PMCID: PMC1994243; DOI: 10.1016/j.neuroimage.2006.11.032;

Huppert TJ, Allen MS, Benav H, Jones PB, Boas DA. A multicompartment vascular model for inferring baseline and functional changes in cerebral oxygen metabolism and arterial dilation. J Cereb Blood Flow Metab. 2007 Jun; 27(6):1262-79. PMID: 17200678; PMCID: PMC2586902; DOI: 10.1038/sj.jcbfm.9600435;

Themelis G, D'Arceuil H, Diamond SG, Thaker S, Huppert TJ, Boas DA, Franceschini MA. Near-infrared spectroscopy measurement of the pulsatile component of cerebral blood flow and volume from arterial oscillations. J Biomed Opt. 2007 Jan-Feb; 12(1):014033. PMID: 17343508; PMCID: PMC2637815; DOI: 10.1117/1.2710250;

Kumar AT, Raymond SB, Boverman G, Boas DA, Bacskai BJ. Time resolved fluorescence tomography of turbid media based on lifetime contrast. Opt Express. 2006 Dec 11; 14(25):12255-70. PMID: 19529654; PMCID: PMC2700299; DOI: 10.1364/oe.14.012255;

Aguirre AD, Chen Y, Fujimoto JG, Ruvinskaya L, Devor A, Boas DA. Depth-resolved imaging of functional activation in the rat cerebral cortex using optical coherence tomography. Opt Lett. 2006 Dec 01; 31(23):3459-61. PMID: 17099749; PMCID: PMC2293976

Joseph DK, Huppert TJ, Franceschini MA, Boas DA. Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging. Appl Opt. 2006 Nov 01; 45(31):8142-51. PMID: 17068557

Carp SA, Kauffman T, Fang Q, Rafferty E, Moore R, Kopans D, Boas D. Compression-induced changes in the physiological state of the breast as observed through frequency domain photon migration measurements. J Biomed Opt. 2006 Nov-Dec; 11(6):064016. PMID: 17212539

Huppert TJ, Hoge RD, Dale AM, Franceschini MA, Boas DA. Quantitative spatial comparison of diffuse optical imaging with blood oxygen level-dependent and arterial spin labeling-based functional magnetic resonance imaging. J Biomed Opt. 2006 Nov-Dec; 11(6):064018. PMID: 17212541; PMCID: PMC2670188; DOI: 10.1117/1.2400910;

Bortfeld H, Wruck E, Boas DA. Assessing infants' cortical response to speech using near-infrared spectroscopy. Neuroimage. 2007 Jan 01; 34(1):407-15. PMID: 17045812; PMCID: PMC1783837; DOI: 10.1016/j.neuroimage.2006.08.010;

Shin HK, Salomone S, Potts EM, Lee SW, Millican E, Noma K, Huang PL, Boas DA, Liao JK, Moskowitz MA, Ayata C. Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms. J Cereb Blood Flow Metab. 2007 May; 27(5):998-1009. PMID: 17033691; PMCID: PMC2614438; DOI: 10.1038/sj.jcbfm.9600406;

Franceschini MA, Joseph DK, Huppert TJ, Diamond SG, Boas DA. Diffuse optical imaging of the whole head. J Biomed Opt. 2006 Sep-Oct; 11(5):054007. PMID: 17092156; PMCID: PMC2637816; DOI: 10.1117/1.2363365;

Custo A, Wells WM, Barnett AH, Hillman EM, Boas DA. Effective scattering coefficient of the cerebral spinal fluid in adult head models for diffuse optical imaging. Appl Opt. 2006 Jul 01; 45(19):4747-55. PMID: 16799690

Selb J, Joseph DK, Boas DA. Time-gated optical system for depth-resolved functional brain imaging. J Biomed Opt. 2006 Jul-Aug; 11(4):044008. PMID: 16965165

Kumar AT, Skoch J, Bacskai BJ, Boas DA, Dunn AK. Fluorescence-lifetime-based tomography for turbid media. Opt Lett. 2005 Dec 15; 30(24):3347-9. PMID: 16389827

Shin HK, Dunn AK, Jones PB, Boas DA, Moskowitz MA, Ayata C. Vasoconstrictive neurovascular coupling during focal ischemic depolarizations. J Cereb Blood Flow Metab. 2006 Aug; 26(8):1018-30. PMID: 16340958

Huppert TJ, Hoge RD, Diamond SG, Franceschini MA, Boas DA. A temporal comparison of BOLD, ASL, and NIRS hemodynamic responses to motor stimuli in adult humans. Neuroimage. 2006 Jan 15; 29(2):368-82. PMID: 16303317; PMCID: PMC2692693; DOI: 10.1016/j.neuroimage.2005.08.065;

Diamond SG, Huppert TJ, Kolehmainen V, Franceschini MA, Kaipio JP, Arridge SR, Boas DA. Dynamic physiological modeling for functional diffuse optical tomography. Neuroimage. 2006 Mar; 30(1):88-101. PMID: 16242967; PMCID: PMC2670202; DOI: 10.1016/j.neuroimage.2005.09.016;

Culver JP, Siegel AM, Franceschini MA, Mandeville JB, Boas DA. Evidence that cerebral blood volume can provide brain activation maps with better spatial resolution than deoxygenated hemoglobin. Neuroimage. 2005 Oct 01; 27(4):947-59. PMID: 16084112

Zhang Y, Brooks DH, Boas DA. A haemodynamic response function model in spatio-temporal diffuse optical tomography. Phys Med Biol. 2005 Oct 07; 50(19):4625-44. PMID: 16177494

Dunn AK, Devor A, Dale AM, Boas DA. Spatial extent of oxygen metabolism and hemodynamic changes during functional activation of the rat somatosensory cortex. Neuroimage. 2005 Aug 15; 27(2):279-90. PMID: 15925522

Boverman G, Miller EL, Li A, Zhang Q, Chaves T, Brooks DH, Boas DA. Quantitative spectroscopic diffuse optical tomography of the breast guided by imperfect a priori structural information. Phys Med Biol. 2005 Sep 07; 50(17):3941-56. PMID: 16177522

Nioka S, Izzetoglu M, Mawn T, Nijland MJ, Boas D, Chance B. Fetal transabdominal pulse oximeter studies using a hypoxic sheep model. J Matern Fetal Neonatal Med. 2005 Jun; 17(6):393-9. PMID: 16009642

Hoge RD, Franceschini MA, Covolan RJ, Huppert T, Mandeville JB, Boas DA. Simultaneous recording of task-induced changes in blood oxygenation, volume, and flow using diffuse optical imaging and arterial spin-labeling MRI. Neuroimage. 2005 Apr 15; 25(3):701-7. PMID: 15808971

Yuan S, Devor A, Boas DA, Dunn AK. Determination of optimal exposure time for imaging of blood flow changes with laser speckle contrast imaging. Appl Opt. 2005 Apr 01; 44(10):1823-30. PMID: 15813518

Li A, Boverman G, Zhang Y, Brooks D, Miller EL, Kilmer ME, Zhang Q, Hillman EM, Boas DA. Optimal linear inverse solution with multiple priors in diffuse optical tomography. Appl Opt. 2005 Apr 01; 44(10):1948-56. PMID: 15813531

Boas DA, Dale AM. Simulation study of magnetic resonance imaging-guided cortically constrained diffuse optical tomography of human brain function. Appl Opt. 2005 Apr 01; 44(10):1957-68. PMID: 15813532

Zhang Q, Brukilacchio TJ, Li A, Stott JJ, Chaves T, Hillman E, Wu T, Chorlton M, Rafferty E, Moore RH, Kopans DB, Boas DA. Coregistered tomographic x-ray and optical breast imaging: initial results. J Biomed Opt. 2005 Mar-Apr; 10(2):024033. PMID: 15910106

Devor A, Ulbert I, Dunn AK, Narayanan SN, Jones SR, Andermann ML, Boas DA, Dale AM. Coupling of the cortical hemodynamic response to cortical and thalamic neuronal activity. Proc Natl Acad Sci U S A. 2005 Mar 08; 102(10):3822-7. PMID: 15734797; PMCID: PMC550644; DOI: 10.1073/pnas.0407789102;

Wilcox T, Bortfeld H, Woods R, Wruck E, Boas DA. Using near-infrared spectroscopy to assess neural activation during object processing in infants. J Biomed Opt. 2005 Jan-Feb; 10(1):11010. PMID: 15847576; PMCID: PMC1769348; DOI: 10.1117/1.1852551;

Selb J, Stott JJ, Franceschini MA, Sorensen AG, Boas DA. Improved sensitivity to cerebral hemodynamics during brain activation with a time-gated optical system: analytical model and experimental validation. J Biomed Opt. 2005 Jan-Feb; 10(1):11013. PMID: 15847579

Zhang Y, Brooks DH, Franceschini MA, Boas DA. Eigenvector-based spatial filtering for reduction of physiological interference in diffuse optical imaging. J Biomed Opt. 2005 Jan-Feb; 10(1):11014. PMID: 15847580

Diamond SG, Huppert TJ, Kolehmainen V, Franceschini MA, Kaipio JP, Arridge SR, Boas DA. Physiological system identification with the Kalman filter in diffuse optical tomography. Med Image Comput Comput Assist Interv. 2005; 8(Pt 2):649-56. PMID: 16686015

Ayata C, Shin HK, Salomone S, Ozdemir-Gursoy Y, Boas DA, Dunn AK, Moskowitz MA. Pronounced hypoperfusion during spreading depression in mouse cortex. J Cereb Blood Flow Metab. 2004 Oct; 24(10):1172-82. PMID: 15529018

Hillman EM, Boas DA, Dale AM, Dunn AK. Laminar optical tomography: demonstration of millimeter-scale depth-resolved imaging in turbid media. Opt Lett. 2004 Jul 15; 29(14):1650-2. PMID: 15309848

Ayata C, Dunn AK, Gursoy-OZdemir Y, Huang Z, Boas DA, Moskowitz MA. Laser speckle flowmetry for the study of cerebrovascular physiology in normal and ischemic mouse cortex. J Cereb Blood Flow Metab. 2004 Jul; 24(7):744-55. PMID: 15241182

Boas DA, Chen K, Grebert D, Franceschini MA. Improving the diffuse optical imaging spatial resolution of the cerebral hemodynamic response to brain activation in humans. Opt Lett. 2004 Jul 01; 29(13):1506-8. PMID: 15259728

Milstein AB, Stott JJ, Oh S, Boas DA, Millane RP, Bouman CA, Webb KJ. Fluorescence optical diffusion tomography using multiple-frequency data. J Opt Soc Am A Opt Image Sci Vis. 2004 Jun; 21(6):1035-49. PMID: 15191186

Li A, Zhang Q, Culver JP, Miller EL, Boas DA. Reconstructing chromosphere concentration images directly by continuous-wave diffuse optical tomography. Opt Lett. 2004 Feb 01; 29(3):256-8. PMID: 14759043

Franceschini MA, Boas DA. Noninvasive measurement of neuronal activity with near-infrared optical imaging. Neuroimage. 2004 Jan; 21(1):372-86. PMID: 14741675; PMCID: PMC3786741

Boas DA, Dale AM, Franceschini MA. Diffuse optical imaging of brain activation: approaches to optimizing image sensitivity, resolution, and accuracy. Neuroimage. 2004; 23 Suppl 1:S275-88. PMID: 15501097

Culver JP, Siegel AM, Stott JJ, Boas DA. Volumetric diffuse optical tomography of brain activity. Opt Lett. 2003 Nov 01; 28(21):2061-3. PMID: 14587815

Li A, Miller EL, Kilmer ME, Brukilacchio TJ, Chaves T, Stott J, Zhang Q, Wu T, Chorlton M, Moore RH, Kopans DB, Boas DA. Tomographic optical breast imaging guided by three-dimensional mammography. Appl Opt. 2003 Sep 01; 42(25):5181-90. PMID: 12962399

Jasdzewski G, Strangman G, Wagner J, Kwong KK, Poldrack RA, Boas DA. Differences in the hemodynamic response to event-related motor and visual paradigms as measured by near-infrared spectroscopy. Neuroimage. 2003 Sep; 20(1):479-88. PMID: 14527608

Boas DA, Strangman G, Culver JP, Hoge RD, Jasdzewski G, Poldrack RA, Rosen BR, Mandeville JB. Can the cerebral metabolic rate of oxygen be estimated with near-infrared spectroscopy? Phys Med Biol. 2003 Aug 07; 48(15):2405-18. PMID: 12953906

Devor A, Dunn AK, Andermann ML, Ulbert I, Boas DA, Dale AM. Coupling of total hemoglobin concentration, oxygenation, and neural activity in rat somatosensory cortex. Neuron. 2003 Jul 17; 39(2):353-9. PMID: 12873390

Franceschini MA, Fantini S, Thompson JH, Culver JP, Boas DA. Hemodynamic evoked response of the sensorimotor cortex measured noninvasively with near-infrared optical imaging. Psychophysiology. 2003 Jul; 40(4):548-60. PMID: 14570163; PMCID: PMC3786740

Prince S, Kolehmainen V, Kaipio JP, Franceschini MA, Boas D, Arridge SR. Time-series estimation of biological factors in optical diffusion tomography. Phys Med Biol. 2003 Jun 07; 48(11):1491-504. PMID: 12817933

Milstein AB, Oh S, Webb KJ, Bouman CA, Zhang Q, Boas DA, Millane RP. Fluorescence optical diffusion tomography. Appl Opt. 2003 Jun 01; 42(16):3081-94. PMID: 12790460

Bamett AH, Culver JP, Sorensen AG, Dale A, Boas DA. Robust inference of baseline optical properties of the human head with three-dimensional segmentation from magnetic resonance imaging. Appl Opt. 2003 Jun 01; 42(16):3095-108. PMID: 12790461

Kilmer ME, Miller EL, Barbaro A, Boas D. Three-dimensional shape-based imaging of absorption perturbation for diffuse optical tomography. Appl Opt. 2003 Jun 01; 42(16):3129-44. PMID: 12790464

Stott JJ, Culver JP, Arridge SR, Boas DA. Optode positional calibration in diffuse optical tomography. Appl Opt. 2003 Jun 01; 42(16):3154-62. PMID: 12790466

Siegel AM, Culver JP, Mandeville JB, Boas DA. Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation. Phys Med Biol. 2003 May 21; 48(10):1391-403. PMID: 12812454

Strangman G, Franceschini MA, Boas DA. Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters. Neuroimage. 2003 Apr; 18(4):865-79. PMID: 12725763

Dunn AK, Devor A, Bolay H, Andermann ML, Moskowitz MA, Dale AM, Boas DA. Simultaneous imaging of total cerebral hemoglobin concentration, oxygenation, and blood flow during functional activation. Opt Lett. 2003 Jan 01; 28(1):28-30. PMID: 12656525

Strangman G, Boas DA, Sutton JP. Non-invasive neuroimaging using near-infrared light. Biol Psychiatry. 2002 Oct 01; 52(7):679-93. PMID: 12372658

Strangman G, Culver JP, Thompson JH, Boas DA. A quantitative comparison of simultaneous BOLD fMRI and NIRS recordings during functional brain activation. Neuroimage. 2002 Oct; 17(2):719-31. PMID: 12377147

Baird AA, Kagan J, Gaudette T, Walz KA, Hershlag N, Boas DA. Frontal lobe activation during object permanence: data from near-infrared spectroscopy. Neuroimage. 2002 Aug; 16(4):1120-5. PMID: 12202098

Boas D, Culver J, Stott J, Dunn A. Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head. Opt Express. 2002 Feb 11; 10(3):159-70. PMID: 19424345

Bolay H, Reuter U, Dunn AK, Huang Z, Boas DA, Moskowitz MA. Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model. Nat Med. 2002 Feb; 8(2):136-42. PMID: 11821897

Franceschini MA, Boas DA, Zourabian A, Diamond SG, Nadgir S, Lin DW, Moore JB, Fantini S. Near-infrared spiroximetry: noninvasive measurements of venous saturation in piglets and human subjects. J Appl Physiol (1985). 2002 Jan; 92(1):372-84. PMID: 11744680; PMCID: PMC3786737

Dunn AK, Bolay H, Moskowitz MA, Boas DA. Dynamic imaging of cerebral blood flow using laser speckle. J Cereb Blood Flow Metab. 2001 Mar; 21(3):195-201. PMID: 11295873

Boas D, Gaudette T, Arridge S. Simultaneous imaging and optode calibration with diffuse optical tomography. Opt Express. 2001 Feb 26; 8(5):263-70. PMID: 19417813

Boas DA, Gaudette T, Strangman G, Cheng X, Marota JJ, Mandeville JB. The accuracy of near infrared spectroscopy and imaging during focal changes in cerebral hemodynamics. Neuroimage. 2001 Jan; 13(1):76-90. PMID: 11133311

Hintz SR, Benaron DA, Siegel AM, Zourabian A, Stevenson DK, Boas DA. Bedside functional imaging of the premature infant brain during passive motor activation. J Perinat Med. 2001; 29(4):335-43. PMID: 11565203

Kilmer M, Miller E, Boas D, Brooks D. A shape-based reconstruction technique for DPDW data. Opt Express. 2000 Dec 18; 7(13):481-91. PMID: 19407900

Dunn A, Boas D. Transport-based image reconstruction in turbid media with small source-detector separations. Opt Lett. 2000 Dec 15; 25(24):1777-9. PMID: 18066341

Zourabian A, Siegel A, Chance B, Ramanujan N, Rode M, Boas DA. Trans-abdominal monitoring of fetal arterial blood oxygenation using pulse oximetry. J Biomed Opt. 2000 Oct; 5(4):391-405. PMID: 11092427

Gaudette RJ, Brooks DH, DiMarzio CA, Kilmer ME, Miller EL, Gaudette T, Boas DA. A comparison study of linear reconstruction techniques for diffuse optical tomographic imaging of absorption coefficient. Phys Med Biol. 2000 Apr; 45(4):1051-70. PMID: 10795991

Benaron DA, Hintz SR, Villringer A, Boas D, Kleinschmidt A, Frahm J, Hirth C, Obrig H, van Houten JC, Kermit EL, Cheong WF, Stevenson DK. Noninvasive functional imaging of human brain using light. J Cereb Blood Flow Metab. 2000 Mar; 20(3):469-77. PMID: 10724111

Siegel A, Marota JJ, Boas D. Design and evaluation of a continuous-wave diffuse optical tomography system. Opt Express. 1999 Apr 12; 4(8):287-98. PMID: 19396285

Cheng X, Boas D. Systematic diffuse optical image errors resulting from uncertainty in the background optical properties. Opt Express. 1999 Apr 12; 4(8):299-307. PMID: 19396286

Cheng X, Boas D. Diffuse optical reflection tomography using continuous wave illumination. Opt Express. 1998 Aug 03; 3(3):118-23. PMID: 19381247

Walker SA, Boas DA, Gratton E. Photon density waves scattered from cylindrical inhomogeneities: theory and experiments. Appl Opt. 1998 Apr 01; 37(10):1935-44. PMID: 18273113

Boas DA, Bizheva KK, Siegel AM. Using dynamic low-coherence interferometry to image Brownian motion within highly scattering media. Opt Lett. 1998 Mar 01; 23(5):319-21. PMID: 18084498

Kelley P, Boas D. Introduction. Opt Express. 1997 Dec 22; 1(13):390. PMID: 19377562

Boas D. A fundamental limitation of linearized algorithms for diffuse optical tomography. Opt Express. 1997 Dec 22; 1(13):404-13. PMID: 19377564

Durduran T, Yodh AG, Chance B, Boas DA. Does the photon-diffusion coefficient depend on absorption? J Opt Soc Am A Opt Image Sci Vis. 1997 Dec; 14(12):3358-65. PMID: 9392901

Boas DA, O'Leary MA, Chance B, Yodh AG. Detection and characterization of optical inhomogeneities with diffuse photon density waves: a signal-to-noise analysis. Appl Opt. 1997 Jan 01; 36(1):75-92. PMID: 18250649

Li XD, O'Leary MA, Boas DA, Chance B, Yodh AG. Fluorescent diffuse photon density waves in homogeneous and heterogeneous turbid media: analytic solutions and applications. Appl Opt. 1996 Jul 01; 35(19):3746-58. PMID: 21102772

O'Leary MA, Boas DA, Li XD, Chance B, Yodh AG. Fluorescence lifetime imaging in turbid media. Opt Lett. 1996 Jan 15; 21(2):158-60. PMID: 19865337

Liu H, Boas DA, Zhang Y, Yodh AG, Chance B. Determination of optical properties and blood oxygenation in tissue using continuous NIR light. Phys Med Biol. 1995 Nov; 40(11):1983-93. PMID: 8587945

O'Leary MA, Boas DA, Chance B, Yodh AG. Experimental images of heterogeneous turbid media by frequency-domain diffusing-photon tomography. Opt Lett. 1995 Mar 01; 20(5):426-8. PMID: 19859209

Boas DA, O'Leary MA, Chance B, Yodh AG. Scattering of diffuse photon density waves by spherical inhomogeneities within turbid media: analytic solution and applications. Proc Natl Acad Sci U S A. 1994 May 24; 91(11):4887-91. PMID: 8197151; PMCID: PMC43894

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 332 publications over 28 distinct years, with a maximum of 23 publications in 2009

Bar chart showing 332 publications over 28 distinct years, with a maximum of 23 publications in 2009

Year	Publications
1994	1
1995	2
1996	2
1997	4
1998	3
1999	2
2000	5
2001	4
2002	6
2003	14
2004	8
2005	19
2006	10
2007	11
2008	20
2009	23
2010	19
2011	16
2012	11
2013	17
2014	12
2015	17
2016	22
2017	21
2018	15
2019	13
2020	21
2021	14