Nancy Kopell, PhD
Boston University College of Arts and Sciences
Dept of Mathematics and Statistics

PhD, University of California, Berkeley
MA, University of California, Berkeley

Nancy Kopell received her B.A. from Cornell University in 1963 and her Ph.D. from Berkeley in 1967. She is currently the William Fairfield Warren Distinguished Professor at Boston University, and co-director of the Center for Computational Neuroscience and Neural Technology (CompNet). She organized and directs the Cognitive Rhythms Collaborative (CRC), a group of over two dozen labs, mostly in the Boston Area, working on brain dyanmics and their cognitive implications.

Kopell's Ph.D. training was in pure mathematics, but she transitioned to applied mathematics shortly after receiving her degree. In the first part of her career, she worked on pattern formation in chemical systems, oscillating systems and problems involving the geometry of systems with multiple time scales. For the last two decades, she has worked on mathematical problems in neuroscience. Her current interests parallel the themes of the CRC: how does the brain produce its dynamics (physiological mechanisms), how do brain rhythms take part in cognition (sensory processing, attention, memory, motor control), and how can pathologies of brain dynamics help to understand symptoms of neurological diseases (Parkinson's disease, schizophrenia, epilepsy) as well as alternate states of consciousness (anesthesia). She collaborates widely with experimentalists and clinicians.

Kopell is a member of the National Academy of Sciences and the American Academy of Arts and Sciences. She was recently selected to be an honorary member of the London Mathematical Society, a distinction given to one or two mathematicians per year worldwide. She has been awarded Sloan Guggenheim, and McArthur Fellowships, and has an honory Ph.D. from the New Jersey Institute of Technology. She has given the Weldon Memorial Prize Lecture (Oxford), the von Neumann Lecture (SIAM) and the Josiah Willard Gibbs Lecture (AMS, as well as multiple other named lectureships.

Boston University
Center for Computational Neuroscience & Neural Technology

Boston University School of Medicine
Pharmacology & Experimental Therapeutics

2011 London Mathematical Society: Honorary Member
2009 SIAM: Fellow
2008 Massachusetts Academy of Sciences: Fellow
2006 Oxford University: Weldon Memorial Prize
2006 New Jersey Institute of Technology: Honorary Doctorate
1996 American Academy of Arts and Sciences: Member
1996 National Academy of Sciences: Member
1990-1995 John D. and Catherine T. MacArthur Fellow
1984-1985 J. S. Guggenheim Fellowship
1975-1977 Alfred P. Sloan Fellow
1963-1964 Woodrow Wilson Fellow (honorary)
1963-1967 N.S.F. Graduate Fellow

Interaction of Time Scales in Forced Rhythmic Networks of Neurons
09/01/2015 - 08/31/2018 (PI)
National Science Foundation

Prefrontal brain rhymes and rule-based action
08/01/2014 - 07/31/2018 (PI)
Department of Defense/ARO

Neurobiology and dynamics of Active Sensing
04/15/2017 - 03/31/2018 (PI)
Trustees Of Columbia University In The C NIH NIMH

Mathematical Modeling Studies of Anesthetic Action
02/10/2017 - 01/31/2018 (PI)
Massachusetts General Hospital NIH NIGMS

Control of Thalamocortical Entrainment: Harnessing Brain Rhythms in Behavior & Cognition
02/18/2016 - 01/31/2018 (PI)
Research Foundation for Mental Hygiene NIH NIMH

Role of REM Sleep in Emotional Memory Consolidation with Implications for Post-Traumatic Stress Disorder
06/16/2017 - 11/15/2017 (PI)
Department of Defense/ARO

07/01/2010 - 09/30/2017 (PI)
National Science Foundation

The Role of Decaying Inhibition in Forced Networks of Neurons
09/15/2012 - 08/31/2016 (PI)
National Science Foundation

CRCNS: Gamma Rhythms and Cell Assemblies
08/01/2009 - 08/31/2015 (PI)
NIH/National Institute of Neurological D

Yr Title Project-Sub Proj Pubs
2017 Project 5: Computational 1P50MH109429-01A1-8843
2017 Project 4: Mathematical Modeling Studies of Anesthetic Action 1P01GM118269-01A1-6047
2017 Control of thalamocortical entrainment: Harnessing brain rhythms in behavior & cognition 5R21MH108981-02
2016 Control of thalamocortical entrainment: Harnessing brain rhythms in behavior & cognition 1R21MH108981-01
2013 CRCNS: Gamma Rhythms and Cell Assemblies 5R01NS067199-05 25
2012 CRCNS: Gamma Rhythms and Cell Assemblies 5R01NS067199-04 25
2011 CRCNS: Gamma Rhythms and Cell Assemblies 5R01NS067199-03 25
2010 CRCNS: Gamma Rhythms and Cell Assemblies 3R01NS067199-02S1 25
2010 High-Frequency Rhythms of the Neocortex: Mechanisms and Interactions 5R01NS062955-02 7
2010 CRCNS: Gamma Rhythms and Cell Assemblies 5R01NS067199-02 25
Showing 10 of 27 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Singer AC, Talei Franzesi G, Kodandaramaiah SB, Flores FJ, Cohen JD, Lee AK, Borgers C, Forest CR, Kopell NJ, Boyden ES. Mesoscale-duration activated states gate spiking in response to fast rises in membrane voltage in the awake brain. J Neurophysiol. 2017 Aug 01; 118(2):1270-1291. PMID: 28566460.
  2. Adams NE, Sherfey JS, Kopell NJ, Whittington MA, LeBeau FE. Hetereogeneity in Neuronal Intrinsic Properties: A Possible Mechanism for Hub-Like Properties of the Rat Anterior Cingulate Cortex during Network Activity. eNeuro. 2017 Jan-Feb; 4(1).View Related Profiles. PMID: 28275720; DOI: 10.1523/ENEURO.0313-16.2017;.
  3. Vijayan S, Lepage KQ, Kopell NJ, Cash SS. Frontal beta-theta network during REM sleep. Elife. 2017 Jan 25; 6. PMID: 28121613; DOI: 10.7554/eLife.18894;.
  4. Kondabolu K, Roberts EA, Bucklin M, McCarthy MM, Kopell N, Han X. Striatal cholinergic interneurons generate beta and gamma oscillations in the corticostriatal circuit and produce motor deficits. Proc Natl Acad Sci U S A. 2016 May 31; 113(22):E3159-68.View Related Profiles. PMID: 27185924; PMCID: PMC4896681; DOI: 10.1073/pnas.1605658113;.
  5. Ainsworth M, Lee S, Kaiser M, Simonotto J, Kopell NJ, Whittington MA. GABAB receptor-mediated, layer-specific synaptic plasticity reorganizes gamma-frequency neocortical response to stimulation. Proc Natl Acad Sci U S A. 2016 May 10; 113(19):E2721-9. PMID: 27118845; PMCID: PMC4868473; DOI: 10.1073/pnas.1605243113;.
  6. Scholvin J, Kinney JP, Bernstein JG, Moore-Kochlacs C, Kopell N, Fonstad CG, Boyden ES. Close-Packed Silicon Microelectrodes for Scalable Spatially Oversampled Neural Recording. IEEE Trans Biomed Eng. 2016 Jan; 63(1):120-30. PMID: 26699649; PMCID: PMC4692190; DOI: 10.1109/TBME.2015.2406113;.
  7. Lee JH, Whittington MA, Kopell NJ. Potential Mechanisms Underlying Intercortical Signal Regulation via Cholinergic Neuromodulators. J Neurosci. 2015 Nov 11; 35(45):15000-14. PMID: 26558772; PMCID: PMC4642235; DOI: 10.1523/JNEUROSCI.0629-15.2015;.
  8. Cannon J, Kopell N, Gardner T, Markowitz J. Neural Sequence Generation Using Spatiotemporal Patterns of Inhibition. PLoS Comput Biol. 2015 Nov; 11(11):e1004581. PMID: 26536029; PMCID: PMC4633124; DOI: 10.1371/journal.pcbi.1004581;.
  9. Kinney JP, Bernstein JG, Meyer AJ, Barber JB, Bolivar M, Newbold B, Scholvin J, Moore-Kochlacs C, Wentz CT, Kopell NJ, Boyden ES. A direct-to-drive neural data acquisition system. Front Neural Circuits. 2015; 9:46. PMID: 26388740; PMCID: PMC4555017; DOI: 10.3389/fncir.2015.00046;.
  10. Vijayan S, Klerman EB, Adler GK, Kopell NJ. Thalamic mechanisms underlying alpha-delta sleep with implications for fibromyalgia. J Neurophysiol. 2015 Sep; 114(3):1923-30. PMID: 26245315; PMCID: PMC4575971; DOI: 10.1152/jn.00280.2015;.
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This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 170 publications over 37 distinct years, with a maximum of 13 publications in 2008

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