Ali Guermazi, MD, PhD
Professor
Boston University School of Medicine
Dept of Radiology
Musculoskeletal Radiology

MD, University of Sfax
PhD, Jikei University School of Medicine




Dr. Guermazi is a French board-certified radiologist. Prior to joining Boston University, he was Director of the Osteoporosis and Arthritis Research Group (OARG) at University of California at San Francisco (UCSF) and then Director of Clinical Research at Synarc, Inc. in San Francisco. Dr. Guermazi interest is musculoskeletal diseases, in particular note are his scientific contributions in the diagnosis and disease progression assessment of osteoarthritis using MRI. His work has focused on identifying structural risk factors for developing and worsening osteoarthritis. Dr. Guermazi had been involved in developing several original and widely accepted radiological methods to assess osteoarthritis disease risk and progression, including the WORMS, BLOKS and MOAKS for the knee, HOAMS for the hip and fixed-flexion radiography for measuring joint space width. Dr. Guermazi has been involved as an MRI reader for the past 14 years in several large U.S. studies including the Health Aging and Body Composition (Health ABC) study, the Boston Osteoarthritis Knee study (BOKS), the Multi-center Osteoarthritis STudy (MOST), the Framingham study, Osteoarthritis Initiative (OAI), and other large NIH-funded studies, as well as several Pharmaceutical-sponsored clinical trials. He is author of over 275 peer-reviewed publications and Investigator on numerous research grants related to MRI reading for Osteoarthritis.

Section Chief
Boston University School of Medicine
Radiology
Musculoskeletal Radiology

Assistant Dean
Boston University School of Medicine
Diversity & Inclusion


Professor
Boston University School of Medicine
Medicine
Rheumatology


2014 100th Scientific Assembly & Annual meeting of the RSNA: Scientific Exhibit Award
2013 14th Annual EULAR Meeting: Abstract Awards in Clinical Science
2012 Radiological Society of North America: Honored Educator Award
2012 98th Scientific Assembly & Annual meeting of the RSNA: Scientific Exhibit Award
2011 97th Scientific Assembly & Annual meeting of the RSNA: Scientific Exhibit Award
2010 96th Scientific Assembly & Annual meeting of the RSNA: Scientific Exhibit Award
2009 95th Scientific Assembly & Annual meeting of the RSNA: Scientific Exhibit Award
2008 94th Scientific Assembly & Annual meeting of the RSNA: Scientific Exhibit Award
2005 17th European Congress of Radiology: Scientific Exhibit Award
2000 The Republic of Congo: Legion of Honor
2000 14th European Congress of Radiology: Scientific Exhibit Award
1998 46th French Congress of Radiology: Special Mention of the Scientific Exhibit
1997 Prizewinner of the European Association of Radiology Exchange Program
1997 10th European Congress of Radiology: Scientific Exhibit Award
1997 Prizewinner of the Visiting Scholar Program of the French Society of Radiology
1996 82nd Scientific Assembly & Annual meeting of the RSNA: Scientific Exhibit Award
1995 Robert Coliez Award of the Scientific Exhibit


Partial Meniscectomy vs. Nonoperative Mgmt. in Meniscal Tear with OA: an RCT
09/05/2020 - 08/31/2024 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
2R01AR055557-11A1

Gadolinium Distribution in Rat Brain After Systemic Administration of Gadolinium-Based Contrast Agents
10/01/2016 - 10/01/2019 (Co-Investigator)
PI: Lee E. Goldstein, MD, PhD
GE Healthcare, Inc.


Characterizing Electrostatic Interactions Between Glycosaminoglycans and Cationic Small Molecules
03/05/2012 - 01/31/2017 (Multi-PI)
PI: Ali Guermazi, MD, PhD
NIH/National Institutes of Health
5R01GM098361-04

Evaluation of Feasibility of Volume Rad X-Ray Versus Conventional X-Ray and 3.0T MRI in Bi-Lateral Knees in With and Without Osteoarthritis
02/01/2009 - 04/30/2010 (PI)
General Electric Company



Tracking Treatable Tissues: Change in qMRI Biomarkers and Future Cartilage Loss
09/15/2017 - 07/31/2021 (PI)
University of Arizona NIH-NIAMS
5R01AR071409-04

Risk of Incident Knee OA and Clinical Outcomes Based on Imaging Biomarkers
09/15/2014 - 07/31/2019 (PI)
University of Arizona NIH-NIAMS

Partial Meniscectomy vs Nonoperative Management in Meniscal Tear with OA: a RCT
08/01/2012 - 07/31/2017 (PI)
Brigham & Women's NIH-NIAMS

Mechanisms and Clinical Importance of Hyperkyphosis: The Framingham Study
09/30/2011 - 08/31/2016 (PI)
Hebrew Rehab C Aged NIH-NIA

Partial meniscectomy vs. nonperative management in meniscal tear with OA: an RCT
09/28/2009 - 09/27/2013 (PI)
Brigham & Women's NIH-NIAMS

Central Reading of Knee MRI in Osteroarthritis Patients
11/01/2008 - 10/31/2011 (PI)
Arthritis Centre of Canada

Osteoartritis Initiave WORMS - BLOKS Comparison Study
04/01/2008 - 10/14/2009 (PI)
Univ of California, San Francisco NIH-NIAMS

Development for a model for the MRI progression of knee osteoarthritis
03/01/2007 - 02/28/2009 (PI)
Arthritis Centre of Canada University of Britis


Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Sayre EC, Guermazi A, Nicolaou S, Esdaile JM, Kopec JA, Singer J, Wong H, Thorne A, Cibere J. A whole-joint, unidimensional, irreversible, and fine-grained MRI knee osteoarthritis severity score, based on cartilage, osteophytes and meniscus (OA-COM). PLoS One. 2021; 16(10):e0258451. PMID: 34648543; PMCID: PMC8516189; DOI: 10.1371/journal.pone.0258451;
     
  2. Katz JN, Collins JE, Jones M, Spindler KP, Marx RG, Mandl LA, Levy BA, Wright R, Jarraya M, Guermazi A, MacFarlane LA, Losina E, Chang Y. Association between structural change over 18 months and subsequent symptom change in middle-aged persons treated for meniscal tear. Arthritis Care Res (Hoboken). 2021 Oct 04.View Related Profiles. PMID: 34606692
     
  3. Go DJ, Kim DH, Kim JY, Guermazi A, Crema MD, Hunter DJ, Kim HA. Serum uric acid and knee osteoarthritis in community residents without gout: a longitudinal study. Rheumatology (Oxford). 2021 Oct 02; 60(10):4581-4590.View Related Profiles. PMID: 33493331
     
  4. Roemer FW, Guermazi A, Demehri S, Wirth W, Kijowski R. Imaging in Osteoarthritis. Osteoarthritis Cartilage. 2021 Sep 22. PMID: 34560261
     
  5. Chalian M, Li X, Guermazi A, Obuchowski NA, Carrino JA, Oei EH, Link TM. The QIBA Profile for MRI-based Compositional Imaging of Knee Cartilage. Radiology. 2021 Sep 07; 204587. PMID: 34491127
     
  6. Messier SP, Newman JJ, Scarlett MJ, Mihalko SL, Miller GD, Nicklas BJ, DeVita P, Hunter DJ, Lyles MF, Eckstein F, Guermazi A, Loeser RF, Beavers DP. Changes in body weight and knee pain in adults with knee osteoarthritis 3.5 years after completing diet and exercise interventions. Arthritis Care Res (Hoboken). 2021 Aug 09. PMID: 34369105
     
  7. Alizai H, Engebretsen L, Jarraya M, Roemer FW, Guermazi A. Wrist injuries detected on magnetic resonance imaging in athletes participating in the Rio de Janeiro 2016 Summer Olympic Games. Quant Imaging Med Surg. 2021 Jul; 11(7):3244-3251. PMID: 34249650; PMCID: PMC8250018; DOI: 10.21037/qims-20-1121;
     
  8. Mohajer B, Kwee RM, Guermazi A, Berenbaum F, Wan M, Zhen G, Cao X, Haugen IK, Demehri S. Metabolic Syndrome and Osteoarthritis Distribution in the Hand Joints: A Propensity Score Matching Analysis From the Osteoarthritis Initiative. J Rheumatol. 2021 Oct; 48(10):1608-1615. PMID: 34329188
     
  9. Hochberg MC, Carrino JA, Schnitzer TJ, Guermazi A, Walsh DA, White A, Nakajo S, Fountaine RJ, Hickman A, Pixton G, Viktrup L, Brown MT, West CR, Verburg KM. Long-Term Safety and Efficacy of Subcutaneous Tanezumab Versus Nonsteroidal Antiinflammatory Drugs for Hip or Knee Osteoarthritis: A Randomized Trial. Arthritis Rheumatol. 2021 07; 73(7):1167-1177. PMID: 33538113
     
  10. Hayashi D, Roemer FW, Guermazi A. How to effectively utilize imaging in disease-modifying treatments for osteoarthritis clinical trials: the radiologist's perspective. Expert Rev Mol Diagn. 2021 Jul; 21(7):673-684. PMID: 34015975
     
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