Ali Guermazi, MD, PhD, MSc
Professor
Boston University Chobanian & Avedisian School of Medicine
Radiology
Musculoskeletal Radiology

MD, University of Sfax
PhD, Jikei University School of Medicine
MSc, Pierre and Marie Curie University (Paris VI)



Ali Guermazi, MD, PhD, MSc is a Professor of Radiology and Medicine, Director of the Quantitative Imaging Center, and Assistant Dean of Diversity and Inclusion at Boston University School of Medicine. He is the Chief of Radiology at the VA Boston Healthcare System. Prior to joining Boston University, he was Director of the Osteoporosis and Arthritis Research Group (OARG) at University of California at San Francisco (UCSF) and then Director of Clinical Research at Synarc, Inc. in San Francisco. Before that, Prof. Guermazi spent 12 years in Paris and worked mainly at the prestigious Saint-Louis University Hospital. Prof. Guermazi obtained his MD from Sfax University (Tunisia), then his specialty from Rene Descartes University in Paris (France) and his PhD from Jikei University in Tokyo (Japan). He is Visiting Professor at Jikei University in Tokyo and the Prefectorial University in Kyoto, Japan.

Prof. Guermazi was Deputy Editor of Radiology for almost 7 years (2013-2019). He is currently Editor-in-Chief of Skeletal Radiology, the official journal of the International Skeletal Radiology and also the President of the International Society of Osteoarthritis Imaging since 2019.

Prof. Guermazi’s interest is in musculoskeletal diseases. Of particular note are his scientific contributions in the diagnosis, incidence and disease progression assessment of osteoarthritis using MRI. His work has focused on identifying structural risk factors for developing and worsening osteoarthritis. Prof. Guermazi has been involved as an MRI reader for the past 25 years in several large U.S. studies including the Health Aging and Body Composition (Health ABC) study, the Boston Osteoarthritis Knee study (BOKS), the Multi-center Osteoarthritis STudy (MOST), the Framingham study, Osteoarthritis Initiative (OAI), and other large NIH-funded studies, as well as several Pharmaceutical-sponsored clinical trials.

Prof. Guermazi is also interested in Interventional nonvascular radiology and imaging in Sports Medicine where he is The Expert Radiologist to the International Olympics Committee and Paris Saint-Germain Football team. Prof. Guermazi is the author of over 670 peer-reviewed PubMed publications, 12 books, over 50 chapters and Investigator on numerous research grants related to MRI reading for Osteoarthritis. His h-index is 111. He is the recipient of many awards among these the OARSI Excellence in Clinical Research in 2018 and the RSNA Margulis Award for the Best Paper in 2022. He has been invited to lecture in more than 70 countries world-wide.

Chief
VA Boston Healthcare System
Radiology


Assistant Dean
Boston University Chobanian & Avedisian School of Medicine
Diversity & Inclusion


Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Rheumatology



Effect of statin intake on Non-traumatic Generalized Knee Osteoarthritis
01/01/2022 - 08/31/2024 (Subcontract PI)
The Johns Hopkins University NIH NIAMS
5R01AR079620-03

Partial Meniscectomy vs. Nonoperative Mgmt. in Meniscal Tear with OA: an RCT
09/05/2020 - 08/31/2024 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS
5R01AR055557-14

Gadolinium Distribution in Rat Brain After Systemic Administration of Gadolinium-Based Contrast Agents
10/01/2016 - 10/01/2019 (Co-Investigator)
PI: Lee E. Goldstein, MD, PhD
GE Healthcare, Inc.


Characterizing Electrostatic Interactions Between Glycosaminoglycans and Cationic Small Molecules
03/05/2012 - 01/31/2017 (Multi-PI)
PI: Ali Guermazi, MD, PhD, MSc
NIH/National Institutes of Health
5R01GM098361-04

Evaluation of Feasibility of Volume Rad X-Ray Versus Conventional X-Ray and 3.0T MRI in Bi-Lateral Knees in With and Without Osteoarthritis
02/01/2009 - 04/30/2010 (PI)
General Electric Company



Tracking Treatable Tissues: Change in qMRI Biomarkers and Future Cartilage Loss
09/15/2017 - 06/30/2022 (Multi-PI)
PI: Ali Guermazi, MD, PhD, MSc
University of Arizona NIH
1R01AR071409-01

Risk of Incident Knee OA and Clinical Outcomes Based on Imaging Biomarkers
09/15/2014 - 08/01/2019 (Subcontract PI)
PI: Ali Guermazi, MD, PhD, MSc
University of Arizona NIH NIA

Partial Meniscectomy vs Nonoperative Management in Meniscal Tear with OA: a RCT
08/01/2012 - 07/31/2017 (PI)
Brigham & Women's NIH-NIAMS

Mechanisms and Clinical Importance of Hyperkyphosis: The Framingham Study
09/30/2011 - 08/31/2016 (PI)
Hebrew Rehab C Aged NIH-NIA

Partial meniscectomy vs. nonperative management in meniscal tear with OA: an RCT
09/28/2009 - 09/27/2013 (PI)
Brigham & Women's NIH-NIAMS

Central Reading of Knee MRI in Osteroarthritis Patients
11/01/2008 - 10/31/2011 (PI)
Arthritis Centre of Canada

Osteoartritis Initiave WORMS - BLOKS Comparison Study
04/01/2008 - 10/14/2009 (PI)
Univ of California, San Francisco NIH-NIAMS

Development for a model for the MRI progression of knee osteoarthritis
03/01/2007 - 02/28/2009 (PI)
Arthritis Centre of Canada University of Britis


Title


Yr Title Project-Sub Proj Pubs
2020 Tracking Treatable Tissues: Change in qMRI Biomarkers and Future Cartilage Loss 5R01AR071409-04
2019 Tracking Treatable Tissues: Change in qMRI Biomarkers and Future Cartilage Loss 5R01AR071409-03
2018 Tracking Treatable Tissues: Change in qMRI Biomarkers and Future Cartilage Loss 5R01AR071409-02
2018 Risk of Incident Knee OA & Clinical Outcomes Based on Imaging Biomarkers 5R01AR066601-05 29
2017 Tracking Treatable Tissues: Change in qMRI Biomarkers and Future Cartilage Loss 1R01AR071409-01
2017 Risk of Incident Knee OA & Clinical Outcomes Based on Imaging Biomarkers 5R01AR066601-04 29
2016 Risk of Incident Knee OA & Clinical Outcomes Based on Imaging Biomarkers 5R01AR066601-03 29
2015 Risk of Incident Knee OA & Clinical Outcomes Based on Imaging Biomarkers 5R01AR066601-02 29
2015 Characterizing electrostatic interactions between glycosaminoglycans and cationic 5R01GM098361-04 16
2014 Risk of Incident Knee OA & Clinical Outcomes Based on Imaging Biomarkers 1R01AR066601-01 29
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Roemer FW, Jansen MP, Maschek S, Mastbergen SC, Marijnissen AK, Wisser A, Heiss R, Weinans HH, Blanco FJ, Berenbaum F, Kloppenburg M, Haugen IK, Eckstein F, Hunter DJ, Guermazi A, Wirth W. Fluctuation of Bone Marrow Lesions and Inflammatory MRI Markers over 2 Years and Concurrent Associations with Quantitative Cartilage Loss. Cartilage. 2024 Oct 26; 19476035241287694. PMID: 39460605; PMCID: PMC11556660; DOI: 10.1177/19476035241287694;
     
  2. Ye C, Leslie WD, Bouxsein ML, Dufour AB, Guermazi A, Habtemariam D, Jarraya M, Kiel DP, Suri P, Samelson EJ. Association of vertebral fractures with worsening degenerative changes of the spine: a longitudinal study. J Bone Miner Res. 2024 Oct 17. PMID: 39418326
     
  3. Chang AH, Roemer FW, Guermazi A, Almagor O, Lee JJ, Chmiel JS, Muhammad LN, Song J, Sharma L. Reply. Arthritis Rheumatol. 2024 Oct 14. PMID: 39400989
     
  4. Liew JW, Petrow E, Tilley S, LaValley MP, Roemer FW, Guermazi A, Lewis CE, Torner J, Nevitt MC, Lynch JA, Felson D. Comparison of definitions of early knee osteoarthritis for likelihood of progression at 2-year and 5-year follow-up: the Multicenter Osteoarthritis Study. Ann Rheum Dis. 2024 Oct 03.View Related Profiles. PMID: 39362696
     
  5. Wáng YXJ, Xiao BH, Leung JCS, Griffith JF, Aparisi Gómez MP, Bazzocchi A, Diacinti D, Chan WP, Guermazi A, Kwok TCY. The observation that older men suffer from hip fracture at DXA T-scores higher than older women and a proposal of a new low BMD category, osteofrailia, for predicting fracture risk in older men. Skeletal Radiol. 2024 Sep 16. PMID: 39284928
     
  6. Chang AH, Roemer FW, Guermazi A, Almagor O, Lee JJ, Chmiel JS, Muhammad LN, Song J, Sharma L. Do Existing MRI Definitions of Knee Osteoarthritis Identify Knees That Will Develop Clinically Significant Disease Over Up To 11 Years of Follow-Up? Arthritis Rheumatol. 2024 Sep 04. PMID: 39229747
     
  7. Guermazi A. Two studies of nerve growth factor (NGF) inhibitors implemented a rigorous mitigation plan to exclude osteoarthritis patients with a risk of joint collapse, but it was still not enough! Osteoarthritis Cartilage. 2024 Dec; 32(12):1518-1521. PMID: 39237025
     
  8. Moradi K, Mohammadi S, Roemer FW, Momtazmanesh S, Hathaway Q, Ibad HA, Hunter DJ, Guermazi A, Demehri S. Progression of Bone Marrow Lesions and the Development of Knee Osteoarthritis: Osteoarthritis Initiative Data. Radiology. 2024 Sep; 312(3):e240470. PMID: 39287521; PMCID: PMC11449232; DOI: 10.1148/radiol.240470;
     
  9. Link TM, Palmer WE, Guermazi A. Introduction to the International Skeletal Society 50-Year Anniversary Special Issue-50 years of labor, adaptation, and success. Skeletal Radiol. 2024 Sep; 53(9):1665-1666. PMID: 38949679
     
  10. Guermazi A. Navigating the future of artificial intelligence and fracture detection of the spine and extremities-"friend not foe". Eur Radiol. 2024 Jul 29. PMID: 39075302
     
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