Ali Guermazi, MD, PhD
Boston University Chobanian & Avedisian School of Medicine
Musculoskeletal Radiology

MD, University of Sfax
PhD, Jikei University School of Medicine

Dr. Guermazi is a French board-certified radiologist. Prior to joining Boston University, he was Director of the Osteoporosis and Arthritis Research Group (OARG) at University of California at San Francisco (UCSF) and then Director of Clinical Research at Synarc, Inc. in San Francisco. Dr. Guermazi interest is musculoskeletal diseases, in particular note are his scientific contributions in the diagnosis and disease progression assessment of osteoarthritis using MRI. His work has focused on identifying structural risk factors for developing and worsening osteoarthritis. Dr. Guermazi had been involved in developing several original and widely accepted radiological methods to assess osteoarthritis disease risk and progression, including the WORMS, BLOKS and MOAKS for the knee, HOAMS for the hip and fixed-flexion radiography for measuring joint space width. Dr. Guermazi has been involved as an MRI reader for the past 14 years in several large U.S. studies including the Health Aging and Body Composition (Health ABC) study, the Boston Osteoarthritis Knee study (BOKS), the Multi-center Osteoarthritis STudy (MOST), the Framingham study, Osteoarthritis Initiative (OAI), and other large NIH-funded studies, as well as several Pharmaceutical-sponsored clinical trials. He is author of over 275 peer-reviewed publications and Investigator on numerous research grants related to MRI reading for Osteoarthritis.

Section Chief
Boston University Chobanian & Avedisian School of Medicine
Musculoskeletal Radiology

Assistant Dean
Boston University Chobanian & Avedisian School of Medicine
Diversity & Inclusion

Boston University Chobanian & Avedisian School of Medicine

Partial Meniscectomy vs. Nonoperative Mgmt. in Meniscal Tear with OA: an RCT
09/05/2020 - 08/31/2024 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NIAMS

Effect of statin intake on Non-traumatic Generalized Knee Osteoarthritis
01/01/2022 - 08/31/2023 (Subcontract PI)
Johns Hopkins University NIH NIAMS

Gadolinium Distribution in Rat Brain After Systemic Administration of Gadolinium-Based Contrast Agents
10/01/2016 - 10/01/2019 (Co-Investigator)
PI: Lee E. Goldstein, MD, PhD
GE Healthcare, Inc.

Characterizing Electrostatic Interactions Between Glycosaminoglycans and Cationic Small Molecules
03/05/2012 - 01/31/2017 (Multi-PI)
PI: Ali Guermazi, MD, PhD
NIH/National Institutes of Health

Evaluation of Feasibility of Volume Rad X-Ray Versus Conventional X-Ray and 3.0T MRI in Bi-Lateral Knees in With and Without Osteoarthritis
02/01/2009 - 04/30/2010 (PI)
General Electric Company

Tracking Treatable Tissues: Change in qMRI Biomarkers and Future Cartilage Loss
09/15/2017 - 06/30/2022 (PI)
University of Arizona NIH-NIAMS

Risk of Incident Knee OA and Clinical Outcomes Based on Imaging Biomarkers
09/15/2014 - 08/01/2019 (PI)
University of Arizona NIH-NIAMS

Partial Meniscectomy vs Nonoperative Management in Meniscal Tear with OA: a RCT
08/01/2012 - 07/31/2017 (PI)
Brigham & Women's NIH-NIAMS

Mechanisms and Clinical Importance of Hyperkyphosis: The Framingham Study
09/30/2011 - 08/31/2016 (PI)
Hebrew Rehab C Aged NIH-NIA

Partial meniscectomy vs. nonperative management in meniscal tear with OA: an RCT
09/28/2009 - 09/27/2013 (PI)
Brigham & Women's NIH-NIAMS

Central Reading of Knee MRI in Osteroarthritis Patients
11/01/2008 - 10/31/2011 (PI)
Arthritis Centre of Canada

Osteoartritis Initiave WORMS - BLOKS Comparison Study
04/01/2008 - 10/14/2009 (PI)
Univ of California, San Francisco NIH-NIAMS

Development for a model for the MRI progression of knee osteoarthritis
03/01/2007 - 02/28/2009 (PI)
Arthritis Centre of Canada University of Britis


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Guermazi A, Roemer FW, Jarraya M, Hayashi D. A call for screening MRI as a tool for osteoarthritis clinical trials. Skeletal Radiol. 2023 May 01. PMID: 37126081
  2. Nguyen T, Hermann AL, Ventre J, Ducarouge A, Pourchot A, Marty V, Regnard NE, Guermazi A. High performance for bone age estimation with an artificial intelligence solution. Diagn Interv Imaging. 2023 Apr 22. PMID: 37095034
  3. Jarraya M, Guermazi A, Liew JW, Tolstykh I, Lynch JA, Aliabadi P, Felson DT, Clancy M, Nevitt M, Lewis CE, Torner J, Neogi T. Prevalence of intra-articular mineralization on knee computed tomography: the multicenter osteoarthritis study. Osteoarthritis Cartilage. 2023 Apr 22.View Related Profiles. PMID: 37088266
  4. Mohajer B, Moradi K, Guermazi A, Mammen JSR, Hunter DJ, Roemer FW, Demehri S. Levothyroxine use and longitudinal changes in thigh muscles in at-risk participants for knee osteoarthritis: preliminary analysis from Osteoarthritis Initiative cohort. Arthritis Res Ther. 2023 Apr 11; 25(1):58. PMID: 37041609; PMCID: PMC10088133; DOI: 10.1186/s13075-023-03012-y;
  5. Ibad HA, Mammen JS, Simonsick EM, Kwoh CK, Guermazi A, Demehri S. Higher thyroid hormone has a negative association with lower limb lean body mass in euthyroid older adults: Analysis from the Baltimore Longitudinal study of aging. Front Aging. 2023; 4:1150645. PMID: 37114095; PMCID: PMC10126399; DOI: 10.3389/fragi.2023.1150645;
  6. Guermazi A, Roemer FW, Crema MD, Jarraya M, Mobasheri A, Hayashi D. Strategic application of imaging in DMOAD clinical trials: focus on eligibility, drug delivery, and semiquantitative assessment of structural progression. Ther Adv Musculoskelet Dis. 2023; 15:1759720X231165558.View Related Profiles. PMID: 37063459; PMCID: PMC10103249; DOI: 10.1177/1759720X231165558;
  7. Gilles G, Vohra A, Robles D, Taljanovic MS, Ashbeck EL, Caruso C, Duryea J, Bedrick EJ, Guermazi A, Kwoh CK. Reliability and Validity of Single Axial Slice vs. Multiple Slice Quantitative Measurement of the Volume of Effusion-Synovitis on 3T Knee MRI in Knees with Osteoarthritis. J Clin Med. 2023 Apr 04; 12(7). PMID: 37048775; PMCID: PMC10095125; DOI: 10.3390/jcm12072691;
  8. Epelboym Y, Mandell JC, Collins JE, Burch E, Shiang T, Killoran T, Macfarlane L, Guermazi A. Genicular Artery Embolization as a Treatment for Osteoarthritis Related Knee Pain: A Systematic Review and Meta-analysis. Cardiovasc Intervent Radiol. 2023 Mar 29. PMID: 36991094
  9. Demehri S, Kasaeian A, Roemer FW, Guermazi A. Osteoarthritis year in review 2022: imaging. Osteoarthritis Cartilage. 2023 Mar 15. PMID: 36924919
  10. Costello KE, Felson DT, Jafarzadeh SR, Guermazi A, Roemer FW, Segal NA, Lewis CE, Nevitt MC, Lewis CL, Kolachalama VB, Kumar D. Gait, physical activity and tibiofemoral cartilage damage: a longitudinal machine learning analysis in the Multicenter Osteoarthritis Study. Br J Sports Med. 2023 Mar 03.View Related Profiles. PMID: 36868795; DOI: 10.1136/bjsports-2022-106142;
Showing 10 of 713 results. Show More