Aaron Colby, PhD
Research Assistant Professor
Boston University College of Engineering
Dept of Biomedical Engineering

PhD, Boston University
MS, Boston University
BS, Boston University

Dr. Aaron Colby is a Research Assistant Professor in the Department of Biomedical Engineering at Boston University. His research interests include the design of new biomaterials and novel drug delivery systems with a particular emphasis on navigating the preclinical path required to translate technologies into the clinic. Aaron completed his postdoctoral degree at Brigham and Women's Hospital and Harvard Medical School under the guidance of Doctor Yolonda L. Colson, M.D./Ph.D. He completed his Ph.D. under the mentorship of Professor Mark Grinstaff at Boston University in 2014, during which time he was a Fellow of both the National Cancer Institute (NCI) funded Cross-Disciplinary Training in Nanotechnology for Cancer (XTNC) program as well as the National Institutes of Health (NIH) Quantitative Biology and Physiology Training program. He is an author or co-author on thirteen peer-reviewed publications, has two patents, and has given nineteen invited lectures, oral presentations or posters. He is a co-founder of several companies that are commercializing his ideas and maintains active partnerships in both industry and academia.

Nanoparticle Synthesis and Shelf-Life
10/01/2020 - 09/30/2022 (PI)
Enspire Bio, Inc


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Lu C, Yang D, Klement JD, Colson YL, Oberlies NH, Pearce CJ, Colby AH, Grinstaff MW, Liu Z, Shi H, Ding HF, Liu K. H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth. Oncogene. 2022 Apr; 41(18):2651-2662.View Related Profiles. PMID: 35351997; PMCID: PMC9058223; DOI: 10.1038/s41388-022-02283-0;
  2. Lu C, Yang D, Klement JD, Colson YL, Oberlies NH, Pearce CJ, Colby AH, Grinstaff MW, Ding HF, Shi H, Liu K. G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes. J Immunother Cancer. 2022 01; 10(1).View Related Profiles. PMID: 35017152; PMCID: PMC8753452; DOI: 10.1136/jitc-2021-003543;
  3. Petersen A, Chu NQ, Fitzgerald DM, McCaslin EZ, Blessing WA, Colby AH, Colson YL, Grinstaff MW. Sustainable glycerol terpolycarbonates as temporary bioadhesives. Biomater Sci. 2021 Dec 07; 9(24):8366-8372.View Related Profiles. PMID: 34787119
  4. Cook KA, Naguib N, Kirsch J, Hohl K, Colby AH, Sheridan R, Rodriguez EK, Nazarian A, Grinstaff MW. In situ gelling and dissolvable hydrogels for use as on-demand wound dressings for burns. Biomater Sci. 2021 Oct 12; 9(20):6842-6850.View Related Profiles. PMID: 34486599; PMCID: PMC8511343; DOI: 10.1039/d1bm00711d;
  5. Colby AH, Liu R, Doyle RP, Merting A, Zhang H, Savage N, Chu NQ, Hollister BA, McCulloch W, Burdette JE, Pearce CJ, Liu K, Oberlies NH, Colson YL, Grinstaff MW. Pilot-scale production of expansile nanoparticles: Practical methods for clinical scale-up. J Control Release. 2021 09 10; 337:144-154.View Related Profiles. PMID: 34280414; PMCID: PMC8489532; DOI: 10.1016/j.jconrel.2021.07.012;
  6. Zhu H, Klement JD, Lu C, Redd PS, Yang D, Smith AD, Poschel DB, Zou J, Liu D, Wang PG, Ostrov D, Coant N, Hannun YA, Colby AH, Grinstaff MW, Liu K. Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis. J Immunol. 2021 03 15; 206(6):1395-1404.View Related Profiles. PMID: 33547170; PMCID: PMC7946776; DOI: 10.4049/jimmunol.2000500;
  7. Al Subeh ZY, Chu NQ, Korunes-Miller JT, Tsai LL, Graf TN, Hung YP, Pearce CJ, Grinstaff MW, Colby AH, Colson YL, Oberlies NH. Delivery of eupenifeldin via polymer-coated surgical buttresses prevents local lung cancer recurrence. J Control Release. 2021 03 10; 331:260-269.View Related Profiles. PMID: 33484778; PMCID: PMC7946725; DOI: 10.1016/j.jconrel.2021.01.026;
  8. Chu NQ, Liu R, Colby A, de Forcrand C, Padera RF, Grinstaff MW, Colson YL. Paclitaxel-loaded expansile nanoparticles improve survival following cytoreductive surgery in pleural mesothelioma xenografts. J Thorac Cardiovasc Surg. 2020 Sep; 160(3):e159-e168.View Related Profiles. PMID: 32044093; PMCID: PMC7354899; DOI: 10.1016/j.jtcvs.2019.12.076;
  9. Salvi A, Amrine CSM, Austin JR, Kilpatrick K, Russo A, Lantvit D, Calderon-Gierszal E, Mattes Z, Pearce CJ, Grinstaff MW, Colby AH, Oberlies NH, Burdette JE. Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage. Mol Cancer Ther. 2020 01; 19(1):89-100.View Related Profiles. PMID: 31909733; PMCID: PMC6951445; DOI: 10.1158/1535-7163.MCT-19-0205;
  10. El-Elimat T, Raja HA, Ayers S, Kurina SJ, Burdette JE, Mattes Z, Sabatelle R, Bacon JW, Colby AH, Grinstaff MW, Pearce CJ, Oberlies NH. Meroterpenoids from Neosetophoma sp.: A Dioxa[4.3.3]propellane Ring System, Potent Cytotoxicity, and Prolific Expression. Org Lett. 2019 01 18; 21(2):529-534.View Related Profiles. PMID: 30620608; PMCID: PMC6343109; DOI: 10.1021/acs.orglett.8b03769;
Showing 10 of 25 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 25 publications over 10 distinct years, with a maximum of 5 publications in 2021


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590 Commonwealth Ave
Boston MA 02215
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