Rutao Cui, MD, PhD
Professor
Boston University School of Medicine
Dept of Pharmacology & Experimental Therapeutics

MD, Shandong Medical University
PhD, Shanghai Medical University



Dr. Cui’s primary research interests include: understanding molecular mechanisms of melanoma development, defining the molecular effects of UVB radiation on melanocyte growth and differentiation, and developing murine genetic models for human melanoma.

Professor
Boston University School of Medicine
Dermatology



2009 American Cancer Society, Chicago IL: IL division Outstanding Mentor
2009 American Cancer Society (ACS): American Cancer Society Research Scholar
2007 Charles A. King Trust Postdoctoral Fellowship Award
2002 Shanghai Scientific Technical Development Prize
2002 World Health Organization (WHO): IARC Fellowship Award
2000 Japan: Takeda Science Award


Molecular Connections Among UV Exposure, Red Hair, Nevi, and Melanoma
12/01/2015 - 11/30/2020 (PI)
NIH/National Cancer Institute
5R01CA193913-03

Why red-haired individuals are so prone to developing melanoma
07/15/2015 - 06/30/2020 (PI)
NIH/National Cancer Institute
5R01CA196896-03

A novel Stat3 targeted acral melanoma therapy via induction of senescence
10/01/2014 - 09/30/2018 (PI)
Melanoma Research Foundation, The


Dot1L is a a Lineage-Specific Tumor Suppressor in Melanocyte
09/15/2015 - 09/14/2018 (PI)
Department of Defense/Army Medical Research Acquisition Activity


The Role of Pheomelanin in Cutaneous Melanoma
06/01/2012 - 05/31/2016 (PI)
NIH/National Cancer Institute
5R01CA137098-07

SIGNALING PATHWAYS FOR UV INDUCED MELANOGENIC RESPONSE AND ITS MIMIC KING
09/01/2010 - 12/31/2013 (PI)
American Cancer Society, Inc.


The role of pheomelanin in cutaneous melanoma
06/01/2009 - 05/31/2012 (PI)
NIH/National Cancer Institute
4R01CA137098-05




Yr Title Project-Sub Proj Pubs
2018 Molecular connections among UV exposure, red hair, nevi and melanoma 5R01CA193913-03
2017 Molecular connections among UV exposure, red hair, nevi and melanoma 5R01CA193913-02
2016 Molecular connections among UV exposure, red hair, nevi and melanoma 1R01CA193913-01A1
2016 Why red-haired individuals are so prone to developing melanoma 5R01CA196896-02
2015 Why red-haired individuals are so prone to developing melanoma 1R01CA196896-01
2014 The role of pheomelanin in cutaneous melanoma 5R01CA137098-07 5
2013 The role of pheomelanin in cutaneous melanoma 5R01CA137098-06 5
2012 The role of pheomelanin in cutaneous melanoma 4R01CA137098-05 5
2010 The role of pheomelanin in cutaneous melanoma 7R01CA137098-04 5
2009 The role of pheomelanin in cutaneous melanoma 1R01CA137098-01A2 5
Showing 10 of 11 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, Liu T, Liu W, Han C, Stawski L, Xu ZX, Zhou G, Chen X, Gao X, Goding CR, Xu N, Cui R, Cao P. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018 May 22.View Related Profiles. PMID: 29786078.
     
  2. Zhu B, Chen S, Wang H, Yin C, Han C, Peng C, Liu Z, Wan L, Zhang X, Zhang J, Lian CG, Ma P, Xu ZX, Prince S, Wang T, Gao X, Shi Y, Liu D, Liu M, Wei W, Wei Z, Pan J, Wang Y, Xuan Z, Hess J, Hayward NK, Goding CR, Chen X, Zhou J, Cui R. The protective role of DOT1L in UV-induced melanomagenesis. Nat Commun. 2018 01 17; 9(1):259. PMID: 29343685.
     
  3. Miao X, Chen S, Zhu B, Yin C, Li X, Han C, Cui R, Li B. Are redheads at an increased risk of melanoma? Future Oncol. 2018 Feb; 14(5):413-416. PMID: 29318914.
     
  4. Chen S, Zhu B, Yin C, Liu W, Han C, Chen B, Liu T, Li X, Chen X, Li C, Hu L, Zhou J, Xu ZX, Gao X, Wu X, Goding CR, Cui R. Palmitoylation-dependent activation of MC1R prevents melanomagenesis. Nature. 2017 09 21; 549(7672):399-403. PMID: 28869973.
     
  5. Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, Song SJ, Lu Y, Liu J, Inuzuka H, Katon JM, Berry K, Fung J, Ng C, Liu P, Song MS, Xue L, Bronson RT, Kirschner MW, Cui R, Pandolfi PP, Wei W. The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function. Cancer Discov. 2017 Apr; 7(4):424-441. PMID: 28174173; DOI: 10.1158/2159-8290.CD-16-0647;.
     
  6. Wang YS, Chen J, Cui F, Wang H, Wang S, Hang W, Zeng Q, Quan CS, Zhai YX, Wang JW, Shen XF, Jian YP, Zhao RX, Werle KD, Cui R, Liang J, Li YL, Xu ZX. LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors. Oncotarget. 2016 Nov 08; 7(45):73389-73401. PMID: 27705915.
     
  7. Zeng Q, Zhao RX, Chen J, Li Y, Li XD, Liu XL, Zhang WM, Quan CS, Wang YS, Zhai YX, Wang JW, Youssef M, Cui R, Liang J, Genovese N, Chow LT, Li YL, Xu ZX. O-linked GlcNAcylation elevated by HPV E6 mediates viral oncogenesis. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):9333-8. PMID: 27482104; PMCID: PMC4995993; DOI: 10.1073/pnas.1606801113;.
     
  8. Robles-Espinoza CD, Roberts ND, Chen S, Leacy FP, Alexandrov LB, Pornputtapong N, Halaban R, Krauthammer M, Cui R, Timothy Bishop D, Adams DJ. Germline MC1R status influences somatic mutation burden in melanoma. Nat Commun. 2016 Jul 12; 7:12064. PMID: 27403562; PMCID: PMC4945874.
     
  9. Li X, Miao X, Wang H, Wang Y, Li F, Yang Q, Cui R, Li B. Association of Serum Uric Acid Levels in Psoriasis: A Systematic Review and Meta-Analysis. Medicine (Baltimore). 2016 May; 95(19):e3676.View Related Profiles. PMID: 27175702; PMCID: PMC4902544; DOI: 10.1097/MD.0000000000003676;.
     
  10. Cao J, Dai X, Wan L, Wang H, Zhang J, Goff PS, Sviderskaya EV, Xuan Z, Xu Z, Xu X, Hinds P, Flaherty KT, Faller DV, Goding CR, Wang Y, Wei W, Cui R. The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth. Sci Signal. 2015 Sep 1; 8(392):ra87.View Related Profiles. PMID: 26329581; DOI: 10.1126/scisignal.aab1995;.
     
Showing 10 of 69 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 69 publications over 21 distinct years, with a maximum of 8 publications in 2001 and 2002

YearPublications
19971
19981
19995
20004
20018
20028
20035
20051
20063
20071
20081
20091
20101
20112
20124
20136
20146
20152
20164
20172
20183

Available to Mentor as: (Review Mentor Role Definitions):
  • Education Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:


72 E. Concord St Housman (R)
Boston MA 02118
Google Map


Cui's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Co-Authors
_
Similar People
_
Same Department