Rutao Cui, MD, PhD
Boston University School of Medicine
Dept of Pharmacology & Experimental Therapeutics

MD, Shandong Medical University
PhD, Shanghai Medical University

Dr. Cui’s primary research interests include: understanding molecular mechanisms of melanoma development, defining the molecular effects of UVB radiation on melanocyte growth and differentiation, and developing murine genetic models for human melanoma.

Boston University School of Medicine

2009 American Cancer Society, Chicago IL: IL division Outstanding Mentor
2009 American Cancer Society (ACS): American Cancer Society Research Scholar
2007 Charles A. King Trust Postdoctoral Fellowship Award
2002 Shanghai Scientific Technical Development Prize
2002 World Health Organization (WHO): IARC Fellowship Award
2000 Japan: Takeda Science Award

The MC1R protein palmitoylation in melanoma development
09/19/2018 - 08/31/2023 (PI)
NIH/National Cancer Institute

Molecular Connections Among UV Exposure, Red Hair, Nevi, and Melanoma
12/01/2015 - 11/30/2020 (PI)
NIH/National Cancer Institute

A novel Stat3 targeted acral melanoma therapy via induction of senescence
10/01/2014 - 09/30/2018 (PI)
Melanoma Research Foundation, The

Dot1L is a a Lineage-Specific Tumor Suppressor in Melanocyte
09/15/2015 - 09/14/2018 (PI)
Department of Defense/Army Medical Research Acquisition Activity

Why red-haired individuals are so prone to developing melanoma
07/15/2015 - 06/30/2018 (PI)
NIH/National Cancer Institute

The Role of Pheomelanin in Cutaneous Melanoma
06/01/2012 - 05/31/2016 (PI)
NIH/National Cancer Institute

09/01/2010 - 12/31/2013 (PI)
American Cancer Society, Inc.

The role of pheomelanin in cutaneous melanoma
06/01/2009 - 05/31/2012 (PI)
NIH/National Cancer Institute

Yr Title Project-Sub Proj Pubs
2019 Molecular connections among UV exposure, red hair, nevi and melanoma 5R01CA193913-04 1
2018 The MC1R protein palmitoylation in melanoma development 1R01CA224432-01A1
2018 Molecular connections among UV exposure, red hair, nevi and melanoma 5R01CA193913-03 1
2017 Molecular connections among UV exposure, red hair, nevi and melanoma 5R01CA193913-02 1
2017 Why red-haired individuals are so prone to developing melanoma 5R01CA196896-03 1
2016 Molecular connections among UV exposure, red hair, nevi and melanoma 1R01CA193913-01A1 1
2016 Why red-haired individuals are so prone to developing melanoma 5R01CA196896-02 1
2015 Why red-haired individuals are so prone to developing melanoma 1R01CA196896-01 1
2014 The role of pheomelanin in cutaneous melanoma 5R01CA137098-07 7
2013 The role of pheomelanin in cutaneous melanoma 5R01CA137098-06 7
Showing 10 of 14 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Chen S, Han C, Miao X, Li X, Yin C, Zou J, Liu M, Li S, Stawski L, Zhu B, Shi Q, Xu ZX, Li C, Goding CR, Zhou J, Cui R. Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads. Nat Commun. 2019 02 20; 10(1):877.View Related Profiles. PMID: 30787281.
  2. Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, Li X, Miao X, Li S, Mi X, Zhang J, Li L, Wei G, Xu ZX, Gao X, Huang C, Wei Z, Goding CR, Wang P, Deng X, Cui R. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. 2019 Feb 21; 176(5):1113-1127.e16.View Related Profiles. PMID: 30712867.
  3. Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, Liu T, Liu W, Han C, Stawski L, Xu ZX, Zhou G, Chen X, Gao X, Goding CR, Xu N, Cui R, Cao P. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018 09; 37(36):4941-4954.View Related Profiles. PMID: 29786078.
  4. Zhu B, Chen S, Wang H, Yin C, Han C, Peng C, Liu Z, Wan L, Zhang X, Zhang J, Lian CG, Ma P, Xu ZX, Prince S, Wang T, Gao X, Shi Y, Liu D, Liu M, Wei W, Wei Z, Pan J, Wang Y, Xuan Z, Hess J, Hayward NK, Goding CR, Chen X, Zhou J, Cui R. The protective role of DOT1L in UV-induced melanomagenesis. Nat Commun. 2018 01 17; 9(1):259. PMID: 29343685.
  5. Miao X, Chen S, Zhu B, Yin C, Li X, Han C, Cui R, Li B. Are redheads at an increased risk of melanoma? Future Oncol. 2018 Feb; 14(5):413-416. PMID: 29318914.
  6. Chen S, Zhu B, Yin C, Liu W, Han C, Chen B, Liu T, Li X, Chen X, Li C, Hu L, Zhou J, Xu ZX, Gao X, Wu X, Goding CR, Cui R. Palmitoylation-dependent activation of MC1R prevents melanomagenesis. Nature. 2017 09 21; 549(7672):399-403. PMID: 28869973.
  7. Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, Song SJ, Lu Y, Liu J, Inuzuka H, Katon JM, Berry K, Fung J, Ng C, Liu P, Song MS, Xue L, Bronson RT, Kirschner MW, Cui R, Pandolfi PP, Wei W. The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function. Cancer Discov. 2017 Apr; 7(4):424-441. PMID: 28174173; DOI: 10.1158/2159-8290.CD-16-0647;.
  8. Wang YS, Chen J, Cui F, Wang H, Wang S, Hang W, Zeng Q, Quan CS, Zhai YX, Wang JW, Shen XF, Jian YP, Zhao RX, Werle KD, Cui R, Liang J, Li YL, Xu ZX. LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors. Oncotarget. 2016 Nov 08; 7(45):73389-73401. PMID: 27705915.
  9. Zeng Q, Zhao RX, Chen J, Li Y, Li XD, Liu XL, Zhang WM, Quan CS, Wang YS, Zhai YX, Wang JW, Youssef M, Cui R, Liang J, Genovese N, Chow LT, Li YL, Xu ZX. O-linked GlcNAcylation elevated by HPV E6 mediates viral oncogenesis. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):9333-8. PMID: 27482104; PMCID: PMC4995993; DOI: 10.1073/pnas.1606801113;.
  10. Robles-Espinoza CD, Roberts ND, Chen S, Leacy FP, Alexandrov LB, Pornputtapong N, Halaban R, Krauthammer M, Cui R, Timothy Bishop D, Adams DJ. Germline MC1R status influences somatic mutation burden in melanoma. Nat Commun. 2016 07 12; 7:12064. PMID: 27403562.
Showing 10 of 71 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 71 publications over 22 distinct years, with a maximum of 8 publications in 2001 and 2002


Available to Mentor as: (Review Mentor Role Definitions):
  • Education Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

72 E. Concord St Housman (R)
Boston MA 02118
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