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PhD, Radboud University Nijmegen
MS, University of Illinois
MS, Wuhan University
DDS, Wuhan University

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Wei G, Darwish G, Oppenheim FG, Schuppan D, Helmerhorst EJ. Commensal Bacterium Rothia aeria Degrades and Detoxifies Gluten via a Highly Effective Subtilisin Enzyme. Nutrients. 2020 Dec 02; 12(12).View Related Profiles.

Oppenheim, Frank
Wei, Guoxian

PMID: 33276655; PMCID: PMC7761627; DOI: 10.3390/nu12123724;

Wei G, Helmerhorst EJ, Darwish G, Blumenkranz G, Schuppan D. Gluten Degrading Enzymes for Treatment of Celiac Disease. Nutrients. 2020 Jul 15; 12(7). PMID: 32679754; PMCID: PMC7400306; DOI: 10.3390/nu12072095;

Darwish G, Helmerhorst EJ, Schuppan D, Oppenheim FG, Wei G. Pharmaceutically modified subtilisins withstand acidic conditions and effectively degrade gluten in vivo. Sci Rep. 2019 05 16; 9(1):7505.View Related Profiles.

Oppenheim, Frank
Wei, Guoxian

PMID: 31097786; PMCID: PMC6522598; DOI: 10.1038/s41598-019-43837-9;

Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, Li X, Miao X, Li S, Mi X, Zhang J, Li L, Wei G, Xu ZX, Gao X, Huang C, Wei Z, Goding CR, Wang P, Deng X, Cui R. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. 2019 02 21; 176(5):1113-1127.e16.View Related Profiles.

Wei, Guoxian
Cui, Rutao
Chen, Shuyang

PMID: 30712867

Tian N, Faller L, Leffler DA, Kelly CP, Hansen J, Bosch JA, Wei G, Paster BJ, Schuppan D, Helmerhorst EJ. Salivary Gluten Degradation and Oral Microbial Profiles in Healthy Individuals and Celiac Disease Patients. Appl Environ Microbiol. 2017 Mar 15; 83(6).View Related Profiles.

Helmerhorst, Eva
Wei, Guoxian
Tian, Na

PMID: 28087531; PMCID: PMC5335528; DOI: 10.1128/AEM.03330-16;

Wei G, Tian N, Siezen R, Schuppan D, Helmerhorst EJ. Identification of food-grade subtilisins as gluten-degrading enzymes to treat celiac disease. Am J Physiol Gastrointest Liver Physiol. 2016 Sep 01; 311(3):G571-80.View Related Profiles.

Helmerhorst, Eva
Wei, Guoxian
Tian, Na

PMID: 27469368; PMCID: PMC5076000; DOI: 10.1152/ajpgi.00185.2016;

Wei G, Tian N, Valery AC, Zhong Y, Schuppan D, Helmerhorst EJ. Identification of Pseudolysin (lasB) as an Aciduric Gluten-Degrading Enzyme with High Therapeutic Potential for Celiac Disease. Am J Gastroenterol. 2015 Jun; 110(6):899-908.View Related Profiles.

Helmerhorst, Eva
Wei, Guoxian
Tian, Na
Zhong, Yi

PMID: 25895519; PMCID: PMC4461489; DOI: 10.1038/ajg.2015.97;

Tian N, Wei G, Schuppan D, Helmerhorst EJ. Effect of Rothia mucilaginosa enzymes on gliadin (gluten) structure, deamidation, and immunogenic epitopes relevant to celiac disease. Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15; 307(8):G769-76.View Related Profiles.

Helmerhorst, Eva
Wei, Guoxian
Tian, Na

PMID: 25147233; PMCID: PMC4200315; DOI: 10.1152/ajpgi.00144.2014;

Helmerhorst EJ, Wei G. Experimental Strategy to Discover Microbes with Gluten-degrading Enzyme Activities. Proc SPIE Int Soc Opt Eng. 2014 May 05; 9112.View Related Profiles.

Helmerhorst, Eva
Wei, Guoxian

PMID: 26113763; PMCID: PMC4477194; DOI: 10.1117/12.2058730;

Fernandez-Feo M, Wei G, Blumenkranz G, Dewhirst FE, Schuppan D, Oppenheim FG, Helmerhorst EJ. The cultivable human oral gluten-degrading microbiome and its potential implications in coeliac disease and gluten sensitivity. Clin Microbiol Infect. 2013 Sep; 19(9):E386-94.View Related Profiles.

Helmerhorst, Eva
Oppenheim, Frank
Wei, Guoxian
Fernandez-Feo, Martin

PMID: 23714165; PMCID: PMC3749263; DOI: 10.1111/1469-0691.12249;

Showing 10 of 37 results. Show More

Zamakhchari M, Wei G, Dewhirst F, Lee J, Schuppan D, Oppenheim FG, Helmerhorst EJ. Identification of Rothia bacteria as gluten-degrading natural colonizers of the upper gastro-intestinal tract. PLoS One. 2011; 6(9):e24455.View Related Profiles.

Helmerhorst, Eva
Oppenheim, Frank
Wei, Guoxian

PMID: 21957450; PMCID: PMC3177827; DOI: 10.1371/journal.pone.0024455;

Wei GX, Xu X, Wu CD. In vitro synergism between berberine and miconazole against planktonic and biofilm Candida cultures. Arch Oral Biol. 2011 Jun; 56(6):565-72. PMID: 21272859; DOI: 10.1016/j.archoralbio.2010.11.021;

Wei GX, Campagna AN, Bobek LA. Factors affecting antimicrobial activity of MUC7 12-mer, a human salivary mucin-derived peptide. Ann Clin Microbiol Antimicrob. 2007; 6:14. PMID: 17996119; PMCID: PMC2211505; DOI: 10.1186/1476-0711-6-14;

Wei GX, Campagna AN, Bobek LA. Effect of MUC7 peptides on the growth of bacteria and on Streptococcus mutans biofilm. J Antimicrob Chemother. 2006 Jun; 57(6):1100-9. PMID: 16595638

Wei GX, Bobek LA. Human salivary mucin MUC7 12-mer-L and 12-mer-D peptides: antifungal activity in saliva, enhancement of activity with protease inhibitor cocktail or EDTA, and cytotoxicity to human cells. Antimicrob Agents Chemother. 2005 Jun; 49(6):2336-42. PMID: 15917530; PMCID: PMC1140489; DOI: 10.1128/AAC.49.6.2336-2342.2005;

Wei GX, Bobek LA. In vitro synergic antifungal effect of MUC7 12-mer with histatin-5 12-mer or miconazole. J Antimicrob Chemother. 2004 May; 53(5):750-8. PMID: 15073161

Situ H, Wei G, Smith CJ, Mashhoon S, Bobek LA. Human salivary MUC7 mucin peptides: effect of size, charge and cysteine residues on antifungal activity. Biochem J. 2003 Oct 1; 375(Pt 1):175-82. PMID: 12812519; PMCID: PMC1223654

Wu CD, Wei GX. Tea as a functional food for oral health. Nutrition. 2002 May; 18(5):443-4. PMID: 11985958

Roberts SK, Wei GX, Wu CD. Evaluating biofilm growth of two oral pathogens. Lett Appl Microbiol. 2002; 35(6):552-6. PMID: 12460443

Cai L, Wei GX, van der Bijl P, Wu CD. Namibian chewing stick, Diospyros lycioides, contains antibacterial compounds against oral pathogens. J Agric Food Chem. 2000 Mar; 48(3):909-14. PMID: 10725172

Wei GX, van der Hoeven JS, Smalley JW, Mikx FH, Fan MW. Proteolysis and utilization of albumin by enrichment cultures of subgingival microbiota. Oral Microbiol Immunol. 1999 Dec; 14(6):348-51. PMID: 10895689

Bian Z, Fan MW, Wei GX, He H, Du MQ. Construction and characteristics of Streptococcus mutans Strain with high level glucosyltransferase expression. Zhonghua Kou Qiang Yi Xue Za Zhi (Chin J Stomatol). 1998; 1(33):40.

Wei G, Qiao W, Bian Z. [Effects of sodium doecyl sulfate on the artificial dental plaque in chemostat]. Zhonghua Kou Qiang Yi Xue Za Zhi. 1997 Nov; 32(6):347-9. PMID: 11189307

Bian Z, Fan M, Wei G. [Ultrastructure of adherence of Streptococcus mutans MT8148 and its glucosyltransferase deficient mutants]. Zhonghua Kou Qiang Yi Xue Za Zhi. 1997 Mar; 32(2):102-4. PMID: 10677961

Wei GX, Qiao WM, Huang YP . Effect of SDS on protein adsorption to hydroxyapatite in vitro and on pellicle formation in vivo. Xiandai Kou Qiang Yi Xue Za Zhi (J Modern Stomatol). 1996; (10):12-14.
Wei GX, Ling JQ. Effect of glucan synthesized in situ in experimental salivary pellicle on the adherence of Streptococcus mutans and Streptococcus sobrinus. Chin J Conservative. 1995; (5):6-8.

Wei G, Xiao Y, Zhang L. [HPLC monitoring and pharmacokinetic study of crevicular fluid concentrations after a single oral dose metronidale]. Zhonghua Kou Qiang Yi Xue Za Zhi. 1995 Jan; 30(1):43-5. PMID: 7789236

Bian Z, Wei GX, Ling JQ. Construction of a shutter vector carrying glucosyltransferease gene between Escherichia coli and Streptococcus mutans. J Comprehensive Stomatol. 1995; (11):280-312.
Ling JQ, Fan MW, Luo W, Wei GX . An experimental research on chlorhexidine controlled release delivery system for root canal disinfection. Chin J Conservative. 1994; (4):76-78.

Fan MW, Wei GX, Liu NH, Ling JQ. [A study on resorbable local metronidazol delivery devices]. Shanghai Kou Qiang Yi Xue. 1992 Jun; 1(1):22-4. PMID: 15159918

Wei GX, Ling JQ . A study of cell-free glucosyltransferase in saliva. J Comprehensive Stomatol. 1992; (8):133-135.
Ling JQ, Fan MW, Wei GX . Detection of DNA G+C mol% in taxonomy of Streptococcus mutans by means of high performance liquid chromatography. Zhonghua Kou Qiang Yi Xue Za Zhi (Chin J Stomatol). 1992; (27):326-328.
Ling JQ, Fan MW ,Wei GX. Antimicrobial effects in vitro of controlled release chlorhexidine delivery system. Chin J of Conservative. 1992; (2):234-236.

Wei GX. [Effect of sodium fluoride on the extracellular glucan production of Streptococcus mutans]. Zhonghua Kou Qiang Yi Xue Za Zhi. 1991 Jan; 26(1):44-7. PMID: 1827760

Wei GX, Fan MW . Effect of chlorhexidine on the mutan-producing Streptococcus mutans. West Chin J Stomatol. 1991; (9):86-88.
Ling JQ, Fan MW, Wei GX, Liu LH. Cloning and Expression of Streptococcus mutans GTF gene in Escherichia coli. J Compreh Stomatol. 1990; (3):129-131.
Ling JQ, Fan MW, Wei GX, Liu LH. Plant Carthamus, Tinctorius L. inhibit extracellular glucan synthesis and aggregation of Streptococcus mutans. West Chin J Stomatol. 1989; (7):217-219.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 3 publications in 1992

Bar chart showing 11 publications over 8 distinct years, with a maximum of 3 publications in 1992

Year	Publications
1989	1
1990	1
1991	1
1992	3
1994	1
1995	2
1996	1
1998	1

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