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Last Name

Stefania Lenna, PhD

TitleResearch Fellow
InstitutionBoston University School of Medicine
DepartmentArthritis Center
Address75 E. Newton St Evans Building
Boston MA 02118
Phone(617) 638-4464
ORCID ORCID Icon0000-0003-1326-0461
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Farina A, Peruzzi G, Lacconi V, Lenna S, Quarta S, Rosato E, Vestri AR, York M, Dreyfus DH, Faggioni A, Morrone S, Trojanowska M, Farina GA. Epstein-Barr virus lytic infection promotes activation of Toll-like receptor 8 innate immune response in systemic sclerosis monocytes. Arthritis Res Ther. 2017 Feb 28; 19(1):39. PMID: 28245863.
    View in: PubMed
  2. Lenna S, Assassi S, Farina GA, Mantero JC, Scorza R, Lafyatis R, Farber HW, Trojanowska M. The HLA-B*35 allele modulates ER stress, inflammation and proliferation in PBMCs from Limited Cutaneous Systemic Sclerosis patients. Arthritis Res Ther. 2015; 17:363. PMID: 26669670.
    View in: PubMed
  3. Lenna S, Han R, Trojanowska M. Endoplasmic reticulum stress and endothelial dysfunction. IUBMB Life. 2014 Aug; 66(8):530-7. PMID: 25130181.
    View in: PubMed
  4. Farina A, Cirone M, York M, Lenna S, Padilla C, McLaughlin S, Faggioni A, Lafyatis R, Trojanowska M, Farina GA. Epstein-Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma. J Invest Dermatol. 2014 Apr; 134(4):954-64. PMID: 24129067.
    View in: PubMed
  5. Cao J, Wan L, Hacker E, Dai X, Lenna S, Jimenez-Cervantes C, Wang Y, Leslie NR, Xu GX, Widlund HR, Ryu B, Alani RM, Dutton-Regester K, Goding CR, Hayward NK, Wei W, Cui R. MC1R is a potent regulator of PTEN after UV exposure in melanocytes. Mol Cell. 2013 Aug 22; 51(4):409-22. PMID: 23973372.
    View in: PubMed
  6. Chrobak I, Lenna S, Stawski L, Trojanowska M. Interferon-? promotes vascular remodeling in human microvascular endothelial cells by upregulating endothelin (ET)-1 and transforming growth factor (TGF) ß2. J Cell Physiol. 2013 Aug; 228(8):1774-83. PMID: 23359533.
    View in: PubMed
  7. Lenna S, Farina AG, Martyanov V, Christmann RB, Wood TA, Farber HW, Scorza R, Whitfield ML, Lafyatis R, Trojanowska M. Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension. Arthritis Rheum. 2013 May; 65(5):1357-66. PMID: 23400395.
    View in: PubMed
  8. Lenna S, Chrobak I, Farina GA, Rodriguez-Pascual F, Lamas S, Lafyatis R, Scorza R, Trojanowska M. HLA-B35 and dsRNA induce endothelin-1 via activation of ATF4 in human microvascular endothelial cells. PLoS One. 2013; 8(2):e56123. PMID: 23441162.
    View in: PubMed
  9. Lenna S, Trojanowska M. The role of endoplasmic reticulum stress and the unfolded protein response in fibrosis. Curr Opin Rheumatol. 2012 Nov; 24(6):663-8. PMID: 22918530.
    View in: PubMed
  10. Samuel GH, Lenna S, Bujor AM, Lafyatis R, Trojanowska M. Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis. J Dermatol Sci. 2012 Sep; 67(3):166-72. PMID: 22771321.
    View in: PubMed
  11. Lenna S, Townsend DM, Tan FK, Kapanadze B, Markiewicz M, Trojanowska M, Scorza R. HLA-B35 upregulates endothelin-1 and downregulates endothelial nitric oxide synthase via endoplasmic reticulum stress response in endothelial cells. J Immunol. 2010 May 1; 184(9):4654-61. PMID: 20335527.
    View in: PubMed
  12. Scorza R, Santaniello A, Salazar G, Lenna S, Della Bella S, Antonioli R, Toussoun K, Beretta L. Effects of aminaftone 75 mg TID on soluble adhesion molecules: a 12-week, randomized, open-label pilot study in patients with systemic sclerosis. Clin Ther. 2008 May; 30(5):924-9. PMID: 18555939.
    View in: PubMed
  13. Scorza R, Santaniello A, Salazar G, Lenna S, Colombo G, Turcatti F, Beretta L. Aminaftone, a derivative of 4-aminobenzoic acid, downregulates endothelin-1 production in ECV304 Cells: an in vitro Study. Drugs R D. 2008; 9(4):251-7. PMID: 18588356.
    View in: PubMed
  14. Santaniello A, Salazar G, Lenna S, Antonioli R, Colombo G, Beretta L, Scorza R. HLA-B35 upregulates the production of endothelin-1 in HLA-transfected cells: a possible pathogenetic role in pulmonary hypertension. Tissue Antigens. 2006 Sep; 68(3):239-44. PMID: 16948645.
    View in: PubMed
  15. Salazar G, Colombo G, Lenna S, Antonioli R, Beretta L, Santaniello A, Scorza R. HLA-B35 influences the apoptosis rate in human peripheral blood mononucleated cells and HLA-transfected cells. Hum Immunol. 2007 Mar; 68(3):181-91. PMID: 17349873.
    View in: PubMed
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