Rosa Breton-Romero, PharmD, PhD
Boston University School of Medicine
Dept of Medicine
Vascular Biology

Dr. Rosa Breton-Romero obtained her Doctor of Pharmacy degree from the Complutense University of Madrid, Spain, in 2007. She undertook her pre-doctoral training focus on the pathological and physiological role of reactive oxygen species in the endothelium and their role in vascular protection under the guidance of Dr. Santiago Lamas, earning a PhD in Biochemistry, Biology, Biomedicine and Biotechnology in 2013 from the Autonomous University of Madrid, Spain. Dr. Rosa Breton-Romero is currently a postdoctoral researcher at the Medicine Department in Boston University School of Medicine under the mentorship of Dr. Naomi Hamburg (2014-Present). Dr. Rosa Breton-Romero current studies concern the mechanism and clinical consequences of insulin resistance and endothelial dysfunction in patients with Type 2 Diabetes mellitus.

2016-2018 American Heart Association: Postdoc Fellowship
2016 Evans Department of Medicine Research Days: First Place Laboratory Clinical Research Award
2014 Evans Department of Medicine Research Days: First Place Laboratory Clinical Research Award
2010 Society for the Free Radicals Research: SFRR- Europe Young Scientist Award
2009 North America Vasculata Biology Organization: Travel Award
2008 Fundacion Renal Inigo Alvarez de Toledo: Predoctoral Fellowship
2008-2012 Spanish Research Council: Predoctoral Fellowship

Contribution of JNK signaling to Endothelial Dysfunction in Human Diabetes Mellitus
01/01/2016 - 12/31/2017 (PI)
American Heart Association

Yr Title Project-Sub Proj Pubs
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Bretón-Romero R, Weisbrod RM, Feng B, Holbrook M, Ko D, Stathos MM, Zhang JY, Fetterman JL, Hamburg NM. Liraglutide Treatment Reduces Endothelial Endoplasmic Reticulum Stress and Insulin Resistance in Patients With Diabetes Mellitus. J Am Heart Assoc. 2018 Sep 18; 7(18):e009379.View Related Profiles. PMID: 30371206; DOI: 10.1161/JAHA.118.009379;.
  2. Bretón-Romero R, Hamburg NM. Every PACE Counts: Learning About Blood Cells and Blood Flow in Peripheral Artery Disease. Circulation. 2017 04 11; 135(15):1429-1431.View Related Profiles. PMID: 28396378; DOI: 10.1161/CIRCULATIONAHA.117.025894;.
  3. Soriano-Carot M, Bretón-Romero R, López-Herraiz J, López-Diego R, Suárez-Fueyo A, Prades GP, Fernandez-Godino R, Navarro-Gomez D, Saguar A, Nieto D, Sánchez-García L, Peropadre B, Castano Z. International mentoring as a new educational approach to alleviate brain drain, empower young talent, and internationalize higher education. Nat Biotechnol. 2017 03 07; 35(3):285-288. PMID: 28267734; DOI: 10.1038/nbt.3822;.
  4. Bretón-Romero R, Wang N, Palmisano J, Larson MG, Vasan RS, Mitchell GF, Benjamin EJ, Vita JA, Hamburg NM. Cross-Sectional Associations of Flow Reversal, Vascular Function, and Arterial Stiffness in the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2016 Dec; 36(12):2452-2459.View Related Profiles. PMID: 27789476.
  5. Farb MG, Karki S, Park SY, Saggese SM, Carmine B, Hess DT, Apovian C, Fetterman JL, Bretón-Romero R, Hamburg NM, Fuster JJ, Zuriaga MA, Walsh K, Gokce N. WNT5A-JNK regulation of vascular insulin resistance in human obesity. Vasc Med. 2016 Dec; 21(6):489-496.View Related Profiles. PMID: 27688298.
  6. Fetterman JL, Holbrook M, Westbrook DG, Brown JA, Feeley KP, Bretón-Romero R, Linder EA, Berk BD, Weisbrod RM, Widlansky ME, Gokce N, Ballinger SW, Hamburg NM. Mitochondrial DNA damage and vascular function in patients with diabetes mellitus and atherosclerotic cardiovascular disease. Cardiovasc Diabetol. 2016 Mar 31; 15:53.View Related Profiles. PMID: 27036979; PMCID: PMC4818501; DOI: 10.1186/s12933-016-0372-y;.
  7. Fetterman JL, Holbrook M, Flint N, Feng B, Bret?n-Romero R, Linder EA, Berk BD, Duess MA, Farb MG, Gokce N, Shirihai OS, Hamburg NM, Vita JA. Restoration of autophagy in endothelial cells from patients with diabetes mellitus improves nitric oxide signaling. Atherosclerosis. 2016 Apr; 247:207-17.View Related Profiles. PMID: 26926601; PMCID: PMC4913892; DOI: 10.1016/j.atherosclerosis.2016.01.043;.
  8. Bretón-Romero R, Feng B, Holbrook M, Farb MG, Fetterman JL, Linder EA, Berk BD, Masaki N, Weisbrod RM, Inagaki E, Gokce N, Fuster JJ, Walsh K, Hamburg NM. Endothelial Dysfunction in Human Diabetes Is Mediated by Wnt5a-JNK Signaling. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):561-9.View Related Profiles. PMID: 26800561; PMCID: PMC4913891; DOI: 10.1161/ATVBAHA.115.306578;.
  9. Tampakakis E, Tabit CE, Holbrook M, Linder EA, Berk BD, Frame AA, Bretón-Romero R, Fetterman JL, Gokce N, Vita JA, Hamburg NM. Intravenous Lipid Infusion Induces Endoplasmic Reticulum Stress in Endothelial Cells and Blood Mononuclear Cells of Healthy Adults. J Am Heart Assoc. 2016 Jan 11; 5(1).View Related Profiles. PMID: 26755554; PMCID: PMC4859375; DOI: 10.1161/JAHA.115.002574;.
  10. Sánchez-Gómez FJ, Calvo E, Bretón-Romero R, Fierro-Fernández M, Anilkumar N, Shah AM, Schröder K, Brandes RP, Vázquez J, Lamas S. NOX4-dependent Hydrogen peroxide promotes shear stress-induced SHP2 sulfenylation and eNOS activation. Free Radic Biol Med. 2015 Dec; 89:419-30. PMID: 26427883; DOI: 10.1016/j.freeradbiomed.2015.08.014;.
Showing 10 of 16 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 16 publications over 8 distinct years, with a maximum of 6 publications in 2016

Contact for Mentoring:

72 East Concord St. Evans 755
Boston MA 02118
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