Paola Divieti Pajevic, MD, PhD
Associate Professor
Boston University Henry M. Goldman School of Dental Medicine
Dept of Molecular & Cell Biology

MD, University of Milan
PhD, University of Florence

Paola Divieti Pajevic, MD, PhD, is an Associate Professor of Molecular and Cell Biology at the Boston University Goldman School of Dental Medicine. She has held this position since 2015. Dr. Divieti Pajevic's current research interest is to understand the role of the Parathyroid Hormone (PTH) receptor, G-saplha and mechanical forces in osteocytes both in vivo and in vitro. For her past research she has received the prestigious John Haddad Young Investigator award.

XLas Relative to Gsa in Bone and Mineral Ion Metabolism
01/28/2017 - 11/30/2020 (PI)
Massachusetts General Hospital NIH NIDDK

Center for Skeletal Research - Core C
06/01/2015 - 05/31/2019 (PI)
Massachusetts General Hospital NIH NIAMS

Effects of Abaloparatide on osteocytes responses to mechanical forces
05/21/2018 - 05/20/2019 (PI)
Radius Health, Inc.

Effects of Osteocyte Specific GsAlpha Signaling on Bone Mass and Hematopoiesis
08/01/2015 - 07/31/2017 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases

03/01/2015 - 02/28/2017 (PI)
Center for the Advancement of Science in Space NASA

Osteocites and Mechano-Transduction
03/02/2015 - 08/31/2016 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases

Yr Title Project-Sub Proj Pubs
2019 Bone Cells Analysis 1P30AR075042-01-5506
2018 Bone Cells and Signaling Core 5P30AR066261-05-6745 53
2017 Bone Cells and Signaling Core 5P30AR066261-04-6745 53
2016 Bone Cells and Signaling Core 5P30AR066261-03-6745 53
2015 Effects of osteocyte specific Gs alpha signaling on bone mass and hematopoiesis 7R01AR060221-05 12
2015 Bone Cells and Signaling Core 5P30AR066261-02-6745 53
2014 Osteocytes and Mechano-Transduction 7UH3AR059655-06 7
2014 Effects of osteocyte specific Gs alpha signaling on bone mass and hematopoiesis 5R01AR060221-04 12
2014 Osteocytes and Mechano-Transduction 5UH3AR059655-05 7
2014 Bone Cells and Signaling Core 1P30AR066261-01-6745 53
Showing 10 of 32 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Sun N, Uda Y, Azab E, Kochen A, Santos RNCE, Shi C, Kobayashi T, Wein MN, Divieti Pajevic P. Effects of histone deacetylase inhibitor Scriptaid and parathyroid hormone on osteocyte functions and metabolism. J Biol Chem. 2019 Jun 21; 294(25):9722-9733.View Related Profiles. PMID: 31068415.
  2. Fulzele K, Dedic C, Lai F, Bouxsein M, Lotinun S, Baron R, Divieti Pajevic P. Loss of Gsa in osteocytes leads to osteopenia due to sclerostin induced suppression of osteoblast activity. Bone. 2018 12; 117:138-148. PMID: 30266511.
  3. Dedic C, Hung TS, Shipley AM, Maeda A, Gardella T, Miller AL, Divieti Pajevic P, Kunkel JG, Rubinacci A. Calcium fluxes at the bone/plasma interface: Acute effects of parathyroid hormone (PTH) and targeted deletion of PTH/PTH-related peptide (PTHrP) receptor in the osteocytes. Bone. 2018 11; 116:135-143. PMID: 30053608.
  4. Divieti Pajevic P, Krause DS. Osteocyte regulation of bone and blood. Bone. 2019 Feb; 119:13-18. PMID: 29458123.
  5. He Q, Bouley R, Liu Z, Wein MN, Zhu Y, Spatz JM, Wang CY, Divieti Pajevic P, Plagge A, Babitt JL, Bastepe M. Large G protein a-subunit XLas limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo. Proc Natl Acad Sci U S A. 2017 11 07; 114(45):E9559-E9568. PMID: 29078380.
  6. Ansari N, Ho PW, Crimeen-Irwin B, Poulton IJ, Brunt AR, Forwood MR, Divieti Pajevic P, Gooi JH, Martin TJ, Sims NA. Autocrine and Paracrine Regulation of the Murine Skeleton by Osteocyte-Derived Parathyroid Hormone-Related Protein. J Bone Miner Res. 2018 01; 33(1):137-153. PMID: 28914969.
  7. Qin Y, Peng Y, Zhao W, Pan J, Ksiezak-Reding H, Cardozo C, Wu Y, Divieti Pajevic P, Bonewald LF, Bauman WA, Qin W. Myostatin inhibits osteoblastic differentiation by suppressing osteocyte-derived exosomal microRNA-218: A novel mechanism in muscle-bone communication. J Biol Chem. 2017 Jun 30; 292(26):11021-11033. PMID: 28465350.
  8. Fulzele K, Lai F, Dedic C, Saini V, Uda Y, Shi C, Tuck P, Aronson JL, Liu X, Spatz JM, Wein MN, Divieti Pajevic P. Osteocyte-Secreted Wnt Signaling Inhibitor Sclerostin Contributes to Beige Adipogenesis in Peripheral Fat Depots. J Bone Miner Res. 2017 Feb; 32(2):373-384.View Related Profiles. PMID: 27653320; DOI: 10.1002/jbmr.3001;.
  9. Spatz JM, Wein MN, Gooi JH, Qu Y, Garr JL, Liu S, Barry KJ, Uda Y, Lai F, Dedic C, Balcells-Camps M, Kronenberg HM, Babij P, Pajevic PD. The Wnt Inhibitor Sclerostin Is Up-regulated by Mechanical Unloading in Osteocytes in Vitro. J Biol Chem. 2015 Jul 3; 290(27):16744-58. PMID: 25953900; PMCID: PMC4505423; DOI: 10.1074/jbc.M114.628313;.
  10. Wein MN, Spatz J, Nishimori S, Doench J, Root D, Babij P, Nagano K, Baron R, Brooks D, Bouxsein M, Pajevic PD, Kronenberg HM. HDAC5 controls MEF2C-driven sclerostin expression in osteocytes. J Bone Miner Res. 2015 Mar; 30(3):400-11. PMID: 25271055; PMCID: PMC4342334; DOI: 10.1002/jbmr.2381;.
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Bar chart showing 50 publications over 20 distinct years, with a maximum of 7 publications in 2012

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700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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