Michael Hasselmo, DPH/DrPH
Professor
Boston University College of Arts and Sciences
Dept of Psychological and Brain Sciences

DPH/DrPH, University of Oxford
PhD, University of Oxford




Michael E. Hasselmo graduated summa cum laude in 1984 from Harvard College with a Special Concentration in Behavioral Neuroscience. He was awarded the Detur Prize and inducted into Phi Beta Kappa in his junior year. He received a Rhodes scholarship to study at Oxford University, where he completed a D.Phil. from the Department of Experimental Psychology in 1988 based on unit recording of face-responsive neurons in monkey temporal lobe cortex. He completed a post-doctoral fellowship in the Division of Biology at the California Institute of Technology from 1988 to 1991 where he published work on modulatory mechanisms in cortical brain slice preparations. He was an Assistant and Associate Professor at Harvard University from 1991-1998 in the Department of Psychology and in the Mind, Brain and Behavior Interfaculty Initiative. He published work on cholinergic modulation of synaptic transmission and spike frequency accomodation in cortical structures, and demonstrated that acetylcholine sets appropriate cortical dynamics for encoding of new information.
He is the Director of the Center for Systems Neuroscience at Boston University. He is the principal investigator on two NIMH R01 grants an ONR MURI award and an NSF EAGER grant for the Initiative on Physics and Mathematics of Neural Systems. He is the Associate Director of the Center for Memory and Brain which is funded by a Silvio O. Conte P50 center grant. Research in the laboratory includes intracellular whole cell patch recordings to analyze modulatory effects and oscillatory dynamics in brain slice preparations of cortical structures, as well as extracellular recording of multiple single units in the entorhinal cortex (including grid cells and head direction cells) and place cells in the hippocampus. His modeling includes network level models and detailed biophysical models. Recent publications address the function of theta rhythm oscillations in generation of grid cell firing and encoding of information in the hippocampus and related cortical structures, building on his earlier models of the role of acetylcholine in regulating mechanisms of encoding and consolidation.

He has published over 120 articles in peer reviewed journals including Science, Nature, Neuron, Trends in Neurosciences, Trends in Cognitive Sciences, Journal of Neuroscience, Journal of Neurophysiology, Neural Computation and Hippocampus. He is a member of the Board of Reviewing Editors at Science, the Computational Neuroscience editor at Hippocampus, an Associate Editor of the Journal of Neuroscience and Frontiers in Systems Neuroscience, and he is on the editorial board of Neurobiology of Learning and Memory, Neural Networks, Network: Computation in Neural Systems, Neuroinformatics, and Brain Structure and Function. He served as president of the International Neural Network Society in 2003, and as program chair for the International Joint Conference on Neural Networks in Portland, Oregon, in July 2003. He is a current member of the board of governors of INNS. He was a co-chair of the 1996 Computational Neuroscience conference and publications chair for the NIPS conference in 1995. He has served as a reviewer and program committee member for the CNS, NIPS, IJCNN and COSYNE conferences.

Professor
Boston University College of Arts and Sciences
Neuroscience


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




Egocentric and Allocentric Spatial Coding in Cortex
08/20/2019 - 05/31/2024 (PI)
NIH/National Institute of Mental Health
5R01MH120073-03

Retrosplenial Cortex Circuit Interactions Supporting Spatial Cognition and Memory
07/15/2021 - 06/30/2023 (Key Person / Mentor)
NIH/National Institute of Neurological Disorders & Stroke
1K99NS119665-01A1

Effects of Stress on Information Processing in the Hippocampal Formation
01/15/2021 - 01/14/2023 (Key Person / Mentor)
Brain & Behavior Research Foundation


Neural Circuits Underlying Symbolic Processing in Primate Cortex and Basal Ganglia
09/01/2016 - 11/30/2022 (PI)
Department of Defense/ONR


NRT UtB: Neurophotonics
09/01/2016 - 08/31/2022 (Multi-PI)
PI: Michael Hasselmo, DPH/DrPH
National Science Foundation
DGE-1633516

COMPARATIVE COGNITION AND HIPPOCAMPAL FUNCTION
09/23/2016 - 06/30/2022 (PI)
NIH/National Institute of Mental Health
5R01MH052090-25

NEUROMODULATION AND CORTICAL MEMORY FUNCTION
02/01/2015 - 01/31/2022 (PI)
NIH/National Institute of Mental Health
5R01MH060013-20

Retrosplenial Cortex Interactions with Entorhinal Cortex and the Visual Anchoring of Spatial Representations
09/30/2017 - 03/31/2021 (Key Person / Mentor)
NIH/National Institute of Neurological Disorders & Stroke
5F32NS101836-04

HIPPOCAMPAL AND CORTICAL CODING IN MEMORY
07/15/2014 - 03/31/2020 (PI)
NIH/National Institute of Mental Health
5R01MH051570-22

MECHANISMS OF ENTORHINAL CORTEX FUNCTION
04/01/2016 - 03/31/2019 (PI)
NIH/National Institute of Mental Health
5R01MH061492-15

Showing 10 of 20 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2022 Egocentric and Allocentric Spatial Coding in Cortex 5R01MH120073-04
2021 Egocentric and Allocentric Spatial Coding in Cortex 5R01MH120073-03
2020 Egocentric and Allocentric Spatial Coding in Cortex 5R01MH120073-02
2020 Comparative Cognition and Hippocampal Function 5R01MH052090-25 45
2019 Egocentric and Allocentric Spatial Coding in Cortex 1R01MH120073-01
2019 Neuromodulation and Cortical Memory Function 5R01MH060013-20 117
2019 Comparative Cognition and Hippocampal Function 5R01MH052090-24 45
2018 Neuromodulation and Cortical Memory Function 5R01MH060013-19 117
2018 Hippocampal and Cortical Coding in Memory 5R01MH051570-22 49
2018 Comparative Cognition and Hippocampal Function 5R01MH052090-23 45
Showing 10 of 66 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Ning W, Bladon JH, Hasselmo ME. Complementary representations of time in the prefrontal cortex and hippocampus. Hippocampus. 2022 Aug; 32(8):577-596. PMID: 35822589; PMCID: PMC9444055; DOI: 10.1002/hipo.23451;
     
  2. Wilmerding LK, Yazdanbakhsh A, Hasselmo ME. Impact of optogenetic pulse design on CA3 learning and replay: A neural model. Cell Rep Methods. 2022 May 23; 2(5):100208. PMID: 35637904; PMCID: PMC9142690; DOI: 10.1016/j.crmeth.2022.100208;
     
  3. Alexander AS, Tung JC, Chapman GW, Conner AM, Shelley LE, Hasselmo ME, Nitz DA. Adaptive integration of self-motion and goals in posterior parietal cortex. Cell Rep. 2022 03 08; 38(10):110504. PMID: 35263604; PMCID: PMC9026715; DOI: 10.1016/j.celrep.2022.110504;
     
  4. Liu Y, Levy S, Mau W, Geva N, Rubin A, Ziv Y, Hasselmo M, Howard M. Consistent population activity on the scale of minutes in the mouse hippocampus. Hippocampus. 2022 May; 32(5):359-372. PMID: 35225408
     
  5. Do Q, Hasselmo ME. Neural circuits and symbolic processing. Neurobiol Learn Mem. 2021 12; 186:107552. PMID: 34763073
     
  6. Carstensen LC, Alexander AS, Chapman GW, Lee AJ, Hasselmo ME. Neural responses in retrosplenial cortex associated with environmental alterations. iScience. 2021 Nov 19; 24(11):103377. PMID: 34825142; PMCID: PMC8605176; DOI: 10.1016/j.isci.2021.103377;
     
  7. Dannenberg H, Lazaro H, Nambiar P, Hoyland A, Hasselmo ME. Effects of visual inputs on neural dynamics for coding of location and running speed in medial entorhinal cortex. Elife. 2020 12 10; 9. PMID: 33300873; PMCID: PMC7773338; DOI: 10.7554/eLife.62500;
     
  8. Alexander AS, Robinson JC, Dannenberg H, Kinsky NR, Levy SJ, Mau W, Chapman GW, Sullivan DW, Hasselmo ME. Neurophysiological coding of space and time in the hippocampus, entorhinal cortex, and retrosplenial cortex. Brain Neurosci Adv. 2020 Jan-Dec; 4:2398212820972871.View Related Profiles. PMID: 33294626; PMCID: PMC7708714; DOI: 10.1177/2398212820972871;
     
  9. Hasselmo ME. Introduction to part two of the special issue on computational models of hippocampus and related structures. Hippocampus. 2020 12; 30(12):1328-1331. PMID: 33185288
     
  10. Levy SJ, Kinsky NR, Mau W, Sullivan DW, Hasselmo ME. Hippocampal spatial memory representations in mice are heterogeneously stable. Hippocampus. 2021 03; 31(3):244-260.View Related Profiles. PMID: 33098619; PMCID: PMC7983370; DOI: 10.1002/hipo.23272;
     
Showing 10 of 229 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 229 publications over 34 distinct years, with a maximum of 16 publications in 2005

YearPublications
19891
19902
19911
19922
19931
19944
19954
19965
19976
19984
19995
20006
20015
20026
20035
20046
200516
200610
200710
200812
20099
20105
20115
201214
201315
201413
20159
20166
201710
201810
20193
202013
20212
20224
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