Elizabeth Bartolak-Suki, MD, DSc
Research Assistant Professor
Boston University College of Engineering
Biomedical Engineering

MD, Albert Szent-Györgyi Medical University
DSc, Semmelweis University of Medicine

Dr. Elizabeth Bartolak-Suki is a Research Assistant Professor in Biomedical Engineering and a Senior Scientist at Boston University. Additionally, she is one of the Principal Investigators in the Cell & Tissue Mechanics Laboratory and interested in how the sensing is achieved via mechanosensitive channels and various transmembrane receptors such as integrins at focal adhesions. She is investigating at the molecular scale, how protein coupling at focal adhesions or cell-cell contacts lead to reorganization of focal adhesions as well as the cytoskeleton followed by molecular signaling cascades, turning genes on or off and eventually expressing various intra- and extracellular proteins. Moreover, these intracellular networks respond to mechanical stimuli not just at the molecular signaling scale but also as a whole at the organelle level, a new concept we introduced and study using live imaging. She developed novel techniques to manipulate and analyze cells and subcellular organelles in dynamic environments that mimic physiological rhythms in the human body. She utilized this stochastic nature of mechanical stimuli to regulate vascular smooth muscle cell contractility toward vascular tissue engineering and to develop new therapeutic strategies for alcohol related vascular malformations.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Bartolák-Suki E, Mondoñedo JR, Suki B. Mechano-inflammatory sensitivity of ACE2: Implications for the regional distribution of SARS-CoV-2 injury in the lung. Respir Physiol Neurobiol. 2022 02; 296:103804.View Related Profiles. PMID: 34678474; PMCID: PMC8524802; DOI: 10.1016/j.resp.2021.103804;
  2. Zeldich D, Bou Jawde S, Herrmann J, Arnaout L, Griffin M, Grunfeld N, Zhang Y, Krishnan R, Bartolák-Suki E, Suki B. Stabilizing breathing pattern using local mechanical vibrations: comparison of deterministic and stochastic stimulations in rodent models of apnea of prematurity. Biomed Eng Lett. 2021 Nov; 11(4):383-392.View Related Profiles. PMID: 34490067; PMCID: PMC8409477; DOI: 10.1007/s13534-021-00203-x;
  3. Mondoñedo JR, Bartolák-Suki E, Bou Jawde S, Nelson K, Cao K, Sonnenberg A, Obrochta WP, Imsirovic J, Ram-Mohan S, Krishnan R, Suki B. A High-Throughput System for Cyclic Stretching of Precision-Cut Lung Slices During Acute Cigarette Smoke Extract Exposure. Front Physiol. 2020; 11:566.View Related Profiles. PMID: 32655401; PMCID: PMC7326018; DOI: 10.3389/fphys.2020.00566;
  4. Li X, Xu J, Bartolák-Suki E, Jiang J, Tien J. Evaluation of 1-mm-diameter endothelialized dense collagen tubes in vascular microsurgery. J Biomed Mater Res B Appl Biomater. 2020 08; 108(6):2441-2449.View Related Profiles. PMID: 32017412; DOI: 10.1002/jbm.b.34576;
  5. Bartolák-Suki E, Suki B. Tuning mitochondrial structure and function to criticality by fluctuation-driven mechanotransduction. Sci Rep. 2020 01 15; 10(1):407.View Related Profiles. PMID: 31941960; PMCID: PMC6962425; DOI: 10.1038/s41598-019-57301-1;
  6. Mellenthin MM, Seong SA, Roy GS, Bartolák-Suki E, Hamlington KL, Bates JHT, Smith BJ. Using injury cost functions from a predictive single-compartment model to assess the severity of mechanical ventilator-induced lung injuries. J Appl Physiol (1985). 2019 07 01; 127(1):58-70. PMID: 31046518; PMCID: PMC6692741; DOI: 10.1152/japplphysiol.00770.2018;
  7. Imsirovic J, Bartolák-Suki E, Jawde SB, Parameswaran H, Suki B. Blood pressure-induced physiological strain variability modulates wall structure and function in aorta rings. Physiol Meas. 2018 10 30; 39(10):105014.View Related Profiles. PMID: 30376453; PMCID: PMC6602053; DOI: 10.1088/1361-6579/aae65f;
  8. Bou Jawde S, Scheuermann A, Bartolák-Suki E, Suki B. The effect of mechanical or electrical stimulation on apnea length in mice. Biomed Eng Lett. 2018 Aug; 8(3):329-335.View Related Profiles. PMID: 30603217; PMCID: PMC6208540; DOI: 10.1007/s13534-018-0076-1;
  9. Bartolák-Suki E, Imsirovic J, Nishibori Y, Krishnan R, Suki B. Regulation of Mitochondrial Structure and Dynamics by the Cytoskeleton and Mechanical Factors. Int J Mol Sci. 2017 Aug 21; 18(8).View Related Profiles. PMID: 28825689; PMCID: PMC5578198; DOI: 10.3390/ijms18081812;
  10. Smith BJ, Bartolak-Suki E, Suki B, Roy GS, Hamlington KL, Charlebois CM, Bates JHT. Linking Ventilator Injury-Induced Leak across the Blood-Gas Barrier to Derangements in Murine Lung Function. Front Physiol. 2017; 8:466.View Related Profiles. PMID: 28736528; PMCID: PMC5500660; DOI: 10.3389/fphys.2017.00466;
Showing 10 of 42 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 42 publications over 18 distinct years, with a maximum of 5 publications in 2015 and 2017


Contact for Mentoring:

44 Cummington St
Boston MA 02215
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