Emanuela Binello | Profiles RNS

Emanuela Binello, MD, PhD, ScD

Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Neurosurgery

MD, Harvard Medical School
ScD, Harvard-MIT Health Sciences and Technology
PhD, Massachusetts Institute of Technology
SM/ScM, Massachusetts Institute of Technology
SB/ScB, Massachusetts Institute of Technology

Websites

Boston Medical Center Provider Profile

ORCID : 0000-0001-7273-1791

Dr. Binello specializes in conditions of brain tumors, pituitary tumors, spine tumors, stereotactic radiosurgery, spinal cord stimulation, peripheral nerve and spine degenerative disease. A prolific researcher, Dr. Binello has authored numerous papers in publications such as Surgical Neurology International, Journal of Neuro-Oncology, and Cancer. Her work has been presented nationally and internationally.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Sconzo D, Penumaka A, Berube M, Wadhwa A, Arunachalam Sakthiyendran N, Balagurunath K, Wetsel Z, Enriquez-Marulanda A, Binello E. Management of civilian ballistic injuries to the spine: practice patterns and recovery outcomes at a level 1 trauma center. J Spine Surg. 2025 Sep 30; 11(3):463-476.View Related Profiles.

Wadhwa , Aryan
Binello, Emanuela

PMID: 41089918; PMCID: PMC12516402; DOI: 10.21037/jss-25-66;

Sconzo D, Wadhwa A, Balagurunath K, Berube M, Wetsel Z, Sakthiyendran NA, Penumaka A, Enriquez-Marulanda A, Ravina K, Binello E. Predictors of seizures in postoperative traumatic brain injury patients: A single center retrospective study. Clin Neurol Neurosurg. 2025 Oct; 257:109116.View Related Profiles.

Wadhwa , Aryan
Sconzo, Daniel
Binello, Emanuela
Berube, Megan

PMID: 40848611

Berube M, Binello E. Chronic type 2 odontoid fracture with atlantoaxial spondyloptosis in an adult: a case report and literature review. J Spine Surg. 2025 Sep 30; 11(3):709-721. PMID: 41089902; PMCID: PMC12516404; DOI: 10.21037/jss-25-5;

Arunachalam Sakthiyendran N, Sconzo D, Wadhwa A, Binello E. Clinical and therapeutic insights into intraventricular metastases from extracranial solid tumors: Patterns, prognosis and management. Mol Clin Oncol. 2025 Sep; 23(3):80.View Related Profiles.

Wadhwa , Aryan
Sconzo, Daniel
Binello, Emanuela
Arunachalam Sakthiyendran, Naveen

PMID: 40692746; PMCID: PMC12278710; DOI: 10.3892/mco.2025.2875;

Hamade YJ, Zhu C, Ogando-Rivas E, Khan M, Arle JE, Binello E, Kasper EM. Technical nuance of ventriculoperitoneal shunt placement in a patient with cutis verticis gyrata: illustrative case. J Neurosurg Case Lessons. 2025 Jun 30; 9(26).View Related Profiles.

Kasper, Ekkehard
Binello, Emanuela

PMID: 40587902; PMCID: PMC12210066; DOI: 10.3171/CASE25174;

Mendieta-Barrera CD, De Nigris Vasconcellos F, Mamani-Julian K, Freeman PI, Garcia-Torrico F, Salolin Vargas VP, Binello E. Comparison of chemonucleolysis and discectomy in the management of lumbar disc herniation: a comprehensive systematic review and meta-analysis. Neurosurg Rev. 2025 Apr 03; 48(1):347. PMID: 40175852

Wetsel ZP, Wadhwa A, Sconzo D, Binello E. Utility of standing radiographs in the evaluation of refractory low back pain and lumbar radiculopathy following a lumbosacral fusion: illustrative case. J Neurosurg Case Lessons. 2025 Mar 03; 9(9).View Related Profiles.

Wadhwa , Aryan
Sconzo, Daniel
Binello, Emanuela

PMID: 40030165; PMCID: PMC11877363; DOI: 10.3171/CASE24555;

Garcia-Torrico F, Mendieta CD, De Nigris Vasconcellos F, Salolin Vargas VP, Scalise M, Mamani-Julian K, Dias Vilela MA, Binello E, Benjamin C. Evaluating the effectiveness and complications of the Retrosigmoid, Translabyrinthine and Middle Fossa approaches in vestibular Schwannoma surgical management: a comprehensive systematic review and meta-analysis of 6,889 patients. Neurosurg Rev. 2025 Feb 10; 48(1):229. PMID: 39930308

Ravina K, Ladner L, Safransky M, Sconzo D, Wetsel ZP, Wadhwa A, Balagurunath K, Ahrens ML, Binello E. Effects of optimal versus suboptimal median household income on the surgically treated traumatic brain injury population at a level I trauma center in the Boston metropolitan area: a propensity score-matched analysis. J Neurosurg. 2025 Apr 01; 142(4):1025-1034.View Related Profiles.

Wadhwa , Aryan
Sconzo, Daniel
Binello, Emanuela
Safransky, Michelle

PMID: 39671591

Windermere SA, Sconzo D, Askari A, Filippidis A, Binello E. Surgeon-led improvement in compliance with use of sequential compression devices in a neurosurgery patient population. BMJ Open Qual. 2024 Aug 05; 13(3).View Related Profiles.

Sconzo, Daniel
Binello, Emanuela

PMID: 39107035; PMCID: PMC11308877; DOI: 10.1136/bmjoq-2024-002807;

Showing 10 of 32 results. Show More

Powers AY, Garcia A, Nwajei F, Binello E. Intraoperative Closed Reduction of Traumatic Lateraloptosis: Operative Nuances. Oper Neurosurg (Hagerstown). 2024 Jan 01; 26(1):86-91. PMID: 37707418

Omofoye OA, Binello E. Intraventricular metastases from rectal carcinoma: case report and literature review. J Biomed Res. 2019 Aug 28; 34(4):318-322. PMID: 32701070; PMCID: PMC7386411; DOI: 10.7555/JBR.33.20180133;

Shoja MM, Rai R, Lachkar S, Iboroma Akobo S, Yilmaz E, Loukas M, Binello E, Gorjaian M, Griessenauer CJ, Iwanaga J, Tubbs RS. The Carotid Sinus Nerve and the First English Translation of Hering's Original Research on this Nerve. Cureus. 2019 Jan 16; 11(1):e3898. PMID: 30911454; PMCID: PMC6424551; DOI: 10.7759/cureus.3898;

Hobert L, Binello E. Trepanation in Ancient China. World Neurosurg. 2017 May; 101:451-456. PMID: 27769950; DOI: 10.1016/j.wneu.2016.10.051;

Bosmia AN, Binello E, Griessenauer CJ, Tubbs RS, Shoja MM. Karl Ewald Konstantin Hering (1834-1918), Heinrich Ewald Hering (1866-1948), and the namesake for the Hering-Breuer reflex. Childs Nerv Syst. 2016 Sep; 32(9):1561-5. PMID: 26243162; DOI: 10.1007/s00381-015-2854-8;

Germano IM, Binello E. Stem cells and gliomas: past, present, and future. J Neurooncol. 2014 Sep; 119(3):547-55. PMID: 25081973; DOI: 10.1007/s11060-014-1498-y;

Tschoe C, Holsapple JW, Binello E. Resection of Primary Brachial Plexus Tumor via a Modified Supraclavicular Approach. J Neurol Surg Rep. 2014 Aug; 75(1):e133-5.View Related Profiles.

Binello, Emanuela
Holsapple, James

PMID: 25083372; PMCID: PMC4110154; DOI: 10.1055/s-0034-1376423;

Thaci B, Brown CE, Binello E, Werbaneth K, Sampath P, Sengupta S. Significance of interleukin-13 receptor alpha 2-targeted glioblastoma therapy. Neuro Oncol. 2014 Oct; 16(10):1304-12.View Related Profiles.

Binello, Emanuela
Sengupta, Sadhak

PMID: 24723564; PMCID: PMC4165413; DOI: 10.1093/neuonc/nou045;

Binello E, Mormone E, Emdad L, Kothari H, Germano IM. Characterization of fenofibrate-mediated anti-proliferative pro-apoptotic effects on high-grade gliomas and anti-invasive effects on glioma stem cells. J Neurooncol. 2014 Apr; 117(2):225-34. PMID: 24493576; DOI: 10.1007/s11060-014-1385-6;

Binello E, Green S, Germano IM. Radiosurgery for high-grade glioma. Surg Neurol Int. 2012; 3(Suppl 2):S118-26. PMID: 22826815; PMCID: PMC3400492; DOI: 10.4103/2152-7806.95423;

Binello E, Qadeer ZA, Kothari HP, Emdad L, Germano IM. Stemness of the CT-2A Immunocompetent Mouse Brain Tumor Model: Characterization In Vitro. J Cancer. 2012; 3:166-74. PMID: 22514559; PMCID: PMC3328782; DOI: 10.7150/jca.4149;

Binello E, Germano IM. Stem cells as therapeutic vehicles for the treatment of high-grade gliomas. Neuro Oncol. 2012 Mar; 14(3):256-65. PMID: 22166262; PMCID: PMC3280798; DOI: 10.1093/neuonc/nor204;

Binello E, Germano IM. Targeting glioma stem cells: a novel framework for brain tumors. Cancer Sci. 2011 Nov; 102(11):1958-66. PMID: 21848914; PMCID: PMC4021040; DOI: 10.1111/j.1349-7006.2011.02064.x;

Binello E, Cunliffe C, Post KD, Kleinman GM. Prolactin-cell adenoma with signet-ring cells: a case report. Clin Neuropathol. 2011 Jul-Aug; 30(4):192-6. PMID: 21726505

Germano IM, Emdad L, Qadeer ZA, Binello E, Uzzaman M. Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis and radiosensitization, and overcomes temozolomide resistance in malignant gliomas. Cancer Gene Ther. 2010 Sep; 17(9):664-74. PMID: 20523363; PMCID: PMC2923667; DOI: 10.1038/cgt.2010.31;

Binello E, Bederson JB, Kleinman GM. Hemangiopericytoma: collision with meningioma and recurrence. Neurol Sci. 2010 Oct; 31(5):625-30. PMID: 20198500; DOI: 10.1007/s10072-010-0227-3;

Germano IM, Binello E. Gene therapy as an adjuvant treatment for malignant gliomas: from bench to bedside. J Neurooncol. 2009 May; 93(1):79-87. PMID: 19430884; DOI: 10.1007/s11060-009-9869-5;

Binello E, Germano IM. Tonsillary carcinoma after temozolomide treatment for glioblastoma multiforme: treatment-related or dual-pathology? J Neurooncol. 2009 Aug; 94(1):145-8. PMID: 19199004; DOI: 10.1007/s11060-009-9806-7;

Gordon CM, Binello E, LeBoff MS, Wohl ME, Rosen CJ, Colin AA. Relationship between insulin-like growth factor I, dehydroepiandrosterone sulfate and proresorptive cytokines and bone density in cystic fibrosis. Osteoporos Int. 2006; 17(5):783-90. PMID: 16541207; PMCID: PMC3206625; DOI: 10.1007/s00198-005-0058-x;

Binello E, Mitchell RN, Harling OK. T cell uptake for the use of boron neutron capture as an immunologic research tool. Appl Radiat Isot. 2004 Nov; 61(5):959-62. PMID: 15308175

Shortkroff S, Binello E, Zhu X, Gierga D, Thornhill TS, Shefer RE, Jones AG, Yanch JC. Dose response of the AIA rabbit stifle joint to boron neutron capture synovectomy. Nucl Med Biol. 2004 Jul; 31(5):663-70. PMID: 15219286

Binello E, Gordon CM. Clinical uses and misuses of dehydroepiandrosterone. Curr Opin Pharmacol. 2003 Dec; 3(6):635-41. PMID: 14644016

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 32 publications over 14 distinct years, with a maximum of 8 publications in 2025

Bar chart showing 32 publications over 14 distinct years, with a maximum of 8 publications in 2025

Year	Publications
2003	1
2004	2
2006	1
2009	2
2010	2
2011	3
2012	2
2014	4
2015	1
2016	1
2019	2
2023	1
2024	2
2025	8

Media Mentions

This Man Underwent Brain Surgery 3,500 Years Ago

Smithsonian Magazine 2/22/2023

Inca Skull Surgeons Had Better Success Rates Than American Civil War Doctors

Smithsonian Magazine 6/13/2018

The Incas were better at skull surgery than Civil War doctors

ZME Science 6/8/2018

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72 E. Concord St Robinson (B)
Boston MA 02118
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617.638.8995

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