Keywords
Last Name

Sadhak Sengupta, PhD

TitleAssistant Professor
InstitutionBoston University School of Medicine
DepartmentNeurosurgery
Address72 E. Concord St Building A
Boston MA 02118
ORCID ORCID Icon0000-0002-5933-4430
 Awards and Honors

Start-EndDescription
2014The American Association of Immunologists: AAI Early Career Faculty Grant
 Research Expertise & Professional Interests
Brain Tumor Immunology & Immunotherapy.
-Chimeric Antigen Receptor (CAR)-expressing T cells.
-New targets for brain tumor immunotherapy.
-Development of immune-memory in CAR T cells.

 NIH RePORTER Grants
 Self-Described Keywords
  • Glioma
  • GBM
  • Immunotherapy
  • T cells
  • CAR
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Sengupta S, Mao G, Gokaslan ZS, Sampath P. Chimeric antigen receptors for treatment of glioblastoma: a practical review of challenges and ways to overcome them. Cancer Gene Ther. 2016 Oct 21. PMID: 27767090.
    View in: PubMed
  2. Sengupta S, Thaci B, Crawford AC, Sampath P. Interleukin-13 receptor alpha 2-targeted glioblastoma immunotherapy. Biomed Res Int. 2014; 2014:952128. PMID: 25247196.
    View in: PubMed
  3. Thaci B, Brown CE, Binello E, Werbaneth K, Sampath P, Sengupta S. Significance of interleukin-13 receptor alpha 2-targeted glioblastoma therapy. Neuro Oncol. 2014 Oct; 16(10):1304-12. PMID: 24723564.
    View in: PubMed
  4. Sengupta S, Marrinan J, Frishman C, Sampath P. Impact of temozolomide on immune response during malignant glioma chemotherapy. Clin Dev Immunol. 2012; 2012:831090. PMID: 23133490.
    View in: PubMed
  5. Kong S, Sengupta S, Tyler B, Bais AJ, Ma Q, Doucette S, Zhou J, Sahin A, Carter BS, Brem H, Junghans RP, Sampath P. Suppression of human glioma xenografts with second-generation IL13R-specific chimeric antigen receptor-modified T cells. Clin Cancer Res. 2012 Nov 1; 18(21):5949-60. PMID: 22966020.
    View in: PubMed
  6. Rolle CE, Sengupta S, Lesniak MS. Mechanisms of immune evasion by gliomas. Adv Exp Med Biol. 2012; 746:53-76. PMID: 22639159.
    View in: PubMed
  7. Wainwright DA, Sengupta S, Han Y, Lesniak MS. Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors. Neuro Oncol. 2011 Dec; 13(12):1308-23. PMID: 21908444.
    View in: PubMed
  8. Sengupta S, Ulasov IV, Thaci B, Ahmed AU, Lesniak MS. Enhanced transduction and replication of RGD-fiber modified adenovirus in primary T cells. PLoS One. 2011; 6(3):e18091. PMID: 21464908.
    View in: PubMed
  9. Wainwright DA, Sengupta S, Han Y, Ulasov IV, Lesniak MS. The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma. PLoS One. 2010; 5(10):e15390. PMID: 21060663.
    View in: PubMed
  10. Sengupta S, Nandi S, Hindi ES, Wainwright DA, Han Y, Lesniak MS. Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model. Neoplasia. 2010 Oct; 12(10):837-47. PMID: 20927322.
    View in: PubMed
  11. Ahmed AU, Rolle CE, Tyler MA, Han Y, Sengupta S, Wainwright DA, Balyasnikova IV, Ulasov IV, Lesniak MS. Bone marrow mesenchymal stem cells loaded with an oncolytic adenovirus suppress the anti-adenoviral immune response in the cotton rat model. Mol Ther. 2010 Oct; 18(10):1846-56. PMID: 20588259.
    View in: PubMed
  12. Balyasnikova IV, Ferguson SD, Sengupta S, Han Y, Lesniak MS. Mesenchymal stem cells modified with a single-chain antibody against EGFRvIII successfully inhibit the growth of human xenograft malignant glioma. PLoS One. 2010; 5(3):e9750. PMID: 20305783.
    View in: PubMed
  13. Rolle CE, Sengupta S, Lesniak MS. Challenges in clinical design of immunotherapy trials for malignant glioma. Neurosurg Clin N Am. 2010 Jan; 21(1):201-14. PMID: 19944979.
    View in: PubMed
  14. Sengupta S, Vitale RJ, Chilton PM, Mitchell TC. Adjuvant induced glucose uptake by activated T cells is not correlated with increased survival. Adv Exp Med Biol. 2008; 614:65-72. PMID: 18290315.
    View in: PubMed
  15. Sengupta S, Jayaraman P, Chilton PM, Casella CR, Mitchell TC. Unrestrained glycogen synthase kinase-3 beta activity leads to activated T cell death and can be inhibited by natural adjuvant. J Immunol. 2007 May 15; 178(10):6083-91. PMID: 17475833.
    View in: PubMed
  16. Sengupta S, Chilton PM, Mitchell TC. Adjuvant-induced survival signaling in clonally expanded T cells is associated with transient increases in pAkt levels and sustained uptake of glucose. Immunobiology. 2005; 210(9):647-59. PMID: 16325488.
    View in: PubMed
  17. Sengupta S, Akbar A, Mukhopadhyay P, Ganguly S, Sen P, Das P. Role of excretory-secretory products of Entamoeba histolytica in human amebiasis. Arch Med Res. 2000 Jul-Aug; 31(4 Suppl):S226-8. PMID: 11070294.
    View in: PubMed
  18. Mukhopadhyay P, Sengupta S, Akbar A, Sengupta K, Bhattacharya S, Debnath A, Ganguly S, Das P. Characterization of plasma membrane-associated antigens of diagnostic and prophylactic importance in Entamoeba histolytica. Arch Med Res. 2000 Jul-Aug; 31(4 Suppl):S21-2. PMID: 11070208.
    View in: PubMed
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