Darren Roblyer, PhD
Associate Professor
Boston University College of Engineering
Biomedical Engineering

PhD, Rice University
BS, Johns Hopkins University

Darren Roblyer is an associate professor of Biomedical Engineering and Electrical and Computer Engineering at Boston University. His research focuses on translational diffuse optical imaging and spectroscopy. His group develops both wearables and frequency-domain near-infrared spectroscopy techniques to address unmet clinical needs in cancer, cardiovascular disease, and kidney disease.

Prof. Roblyer received a B.S. in Biomedical Engineering from Johns Hopkins University in 2004, and received his Ph.D. in Bioengineering at Rice University in 2009. He was a Department of Defense Postdoctoral Fellow at the Beckman Laser Institute at the University of California, Irvine studying under Professor Bruce Tromberg prior to joining the faculty at Boston University in 2012.

Frequency domain shortwave infrared spectroscopy (FD-SWIRS) for volume status monitoring during hemodialysis in end stage kidney disease
03/01/2022 - 01/31/2025 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases

Early breast cancer treatment response monitoring with real-time diffuse optical imaging
09/01/2021 - 08/31/2024 (PI)
Department of Defense/Army Medical Research Acquisition Activity

Multiplexed Imaging in the Near Infrared with Indium Phosphide Quantum Shells
08/01/2022 - 07/31/2024 (Subcontract PI)
Northeastern University NIH NIGMS

Frequency domain diffuse optical spectroscopy and diffuse correlation spectroscopy for assessing inspiratory muscle metabolism in mechanically ventilated patients
09/15/2021 - 06/30/2024 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering

Label-free measurement of blood lipids with hyperspectral short-wave infrared spatial frequency domain imaging to improve cardiovascular disease risk prediction and treatment monitoring
07/01/2020 - 03/31/2024 (PI)
NIH/National Institute of Biomedical Imaging & Bioengineering

A wearable probe for deep tissue imaging of hemodynamics in breast tumors
01/01/2022 - 12/31/2023 (PI)
American Cancer Society, Inc.

Estimating blood pressure changes using laser speckle contrast measurements on the wrist and hand
12/07/2021 - 10/31/2023 (PI)
Facebook Technologies, LLC

EFRI CEE: Optically Controlled Localized Epigenetic Chromatin Remodeling with Photoactivatable CRISPR-dCas9
09/01/2018 - 08/31/2023 (Subcontract PI)
Beth Israel Deaconess Medical Center, Inc. National Science Fdn

Development of less toxic treatment strategies for metastatic and drug resistant breast cancer using noninvasive optical monitoring
09/01/2015 - 08/31/2021 (PI)
Department of Defense/Army Medical Research Acquisition Activity

A wearable probe for deep tissue imaging of hemodynamics in breast tumors
07/01/2018 - 12/31/2020 (PI)
American Cancer Society, Inc.

Showing 10 of 16 results. Show All Results


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Gómez CA, Brochard L, Goligher EC, Rozenberg D, Reid WD, Roblyer D. Combined frequency domain near-infrared spectroscopy and diffuse correlation spectroscopy system for comprehensive metabolic monitoring of inspiratory muscles during loading. J Biomed Opt. 2024 Mar; 29(3):035002. PMID: 38532926; PMCID: PMC10965138; DOI: 10.1117/1.JBO.29.3.035002;
  2. Gómez CA, Brochard L, Goligher EC, Rozenberg D, Reid WD, Roblyer D. A combined frequency domain near infrared spectroscopy and diffuse correlation spectroscopy system for comprehensive metabolic monitoring of inspiratory muscles during loading. bioRxiv. 2023 Dec 01. PMID: 38076980; PMCID: PMC10705398; DOI: 10.1101/2023.11.30.569133;
  3. Fried D, Pierce M, Roblyer D. Special Section Guest Editorial: Short Wave Infrared Techniques and Applications in Biomedical Optics. J Biomed Opt. 2023 Sep; 28(9):094800. PMID: 37692561; PMCID: PMC10492591; DOI: 10.1117/1.JBO.28.9.094800;
  4. Zhang S, Grifno G, Passaro R, Regan K, Zheng S, Hadzipasic M, Banerji R, O'Connor L, Chu V, Kim SY, Yang J, Shi L, Karrobi K, Roblyer D, Grinstaff MW, Nia HT. Intravital measurements of solid stresses in tumours reveal length-scale and microenvironmentally dependent force transmission. Nat Biomed Eng. 2023 Nov; 7(11):1473-1492.View Related Profiles. PMID: 37640900; PMCID: PMC10836235; DOI: 10.1038/s41551-023-01080-8;
  5. Spink SS, Pilvar A, Wei LL, Frias J, Anders K, Franco ST, Rose OC, Freeman M, Bag G, Huang H, Roblyer D. Shortwave infrared diffuse optical wearable probe for quantification of water and lipid content in emulsion phantoms using deep learning. J Biomed Opt. 2023 Sep; 28(9):094808. PMID: 37313427; PMCID: PMC10258729; DOI: 10.1117/1.JBO.28.9.094808;
  6. Pilvar A, Smith DW, Plutzky J, Roblyer D. Feasibility of postprandial optical scattering of lipoproteins in blood as an optical marker of cardiovascular disease risk: modeling and experimental validation. J Biomed Opt. 2023 Jun; 28(6):065002. PMID: 37305780; PMCID: PMC10249051; DOI: 10.1117/1.JBO.28.6.065002;
  7. Pilvar A, Mehendale AM, Karrobi K, El-Adili F, Bujor A, Roblyer D. Spatial frequency domain imaging for the assessment of scleroderma skin involvement. Biomed Opt Express. 2023 Jun 01; 14(6):2955-2968.View Related Profiles. PMID: 37342706; PMCID: PMC10278615; DOI: 10.1364/BOE.489609;
  8. Garrett A, Kim B, Sie EJ, Gurel NZ, Marsili F, Boas DA, Roblyer D. Simultaneous photoplethysmography and blood flow measurements towards the estimation of blood pressure using speckle contrast optical spectroscopy. Biomed Opt Express. 2023 Apr 01; 14(4):1594-1607.View Related Profiles. PMID: 37078049; PMCID: PMC10110303; DOI: 10.1364/BOE.482740;
  9. Karrobi K, Tank A, Fuzail MA, Kalidoss M, Tilbury K, Zaman M, Ferruzzi J, Roblyer D. Fluorescence Lifetime Imaging Microscopy (FLIM) reveals spatial-metabolic changes in 3D breast cancer spheroids. Sci Rep. 2023 Mar 03; 13(1):3624.View Related Profiles. PMID: 36869092; PMCID: PMC9984376; DOI: 10.1038/s41598-023-30403-7;
  10. Pilvar A, Plutzky J, Pierce M, Roblyer D. Shortwave infrared spatial frequency domain imaging for non-invasive measurement of tissue and blood optical properties. J Biomed Opt. 2022 Jun; 27(6). PMID: 35715883; PMCID: PMC9204261; DOI: 10.1117/1.JBO.27.6.066003;
Showing 10 of 74 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 73 publications over 18 distinct years, with a maximum of 8 publications in 2018 and 2020 and 2023

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Boston MA 02215
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