Anthony Leyme
Postdoctoral Fellow
Boston University School of Medicine



Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Maziarz M, Leyme A, Marivin A, Luebbers A, Patel PP, Chen Z, Sprang SR, Garcia-Marcos M. Atypical activation of Gaq by the oncogenic mutation Q209P. J Biol Chem. 2018 Oct 23.View Related Profiles. PMID: 30352874.
     
  2. Leyme A, Marivin A, Maziarz M, DiGiacomo V, Papakonstantinou MP, Patel PP, Blanco-Canosa JB, Walawalkar IA, Rodriguez-Davila G, Dominguez I, Garcia-Marcos M. Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein. Proc Natl Acad Sci U S A. 2017 11 28; 114(48):E10319-E10328.View Related Profiles. PMID: 29133411.
     
  3. de Opakua AI, Parag-Sharma K, DiGiacomo V, Merino N, Leyme A, Marivin A, Villate M, Nguyen LT, de la Cruz-Morcillo MA, Blanco-Canosa JB, Ramachandran S, Baillie GS, Cerione RA, Blanco FJ, Garcia-Marcos M. Molecular mechanism of Gai activation by non-GPCR proteins with a Ga-Binding and Activating motif. Nat Commun. 2017 05 18; 8:15163.View Related Profiles. PMID: 28516903.
     
  4. Parag-Sharma K, Leyme A, DiGiacomo V, Marivin A, Broselid S, Garcia-Marcos M. Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Ga-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling. J Biol Chem. 2016 Dec 30; 291(53):27098-27111.View Related Profiles. PMID: 27864364; DOI: 10.1074/jbc.M116.764431;.
     
  5. Gupta V, Bhandari D, Leyme A, Aznar N, Midde KK, Lo IC, Ear J, Niesman I, López-Sánchez I, Blanco-Canosa JB, von Zastrow M, Garcia-Marcos M, Farquhar MG, Ghosh P. GIV/Girdin activates Gai and inhibits Gas via the same motif. Proc Natl Acad Sci U S A. 2016 09 27; 113(39):E5721-30.View Related Profiles. PMID: 27621449; DOI: 10.1073/pnas.1609502113;.
     
  6. Marivin A, Leyme A, Parag-Sharma K, DiGiacomo V, Cheung AY, Nguyen LT, Dominguez I, Garcia-Marcos M. Dominant-negative Ga subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease. Sci Signal. 2016 Apr 12; 9(423):ra37.View Related Profiles. PMID: 27072656; PMCID: PMC4870087; DOI: 10.1126/scisignal.aad2429;.
     
  7. Leyme A, Marivin A, Garcia-Marcos M. GIV/Girdin (Ga-interacting, Vesicle-associated Protein/Girdin) Creates a Positive Feedback Loop That Potentiates Outside-in Integrin Signaling in Cancer Cells. J Biol Chem. 2016 Apr 8; 291(15):8269-82.View Related Profiles. PMID: 26887938; PMCID: PMC4825026; DOI: 10.1074/jbc.M115.691550;.
     
  8. Ruff M, Leyme A, Le Cann F, Bonnier D, Le Seyec J, Chesnel F, Fattet L, Rimokh R, Baffet G, Théret N. The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-ß-Induced Epithelial to Mesenchymal Transition. PLoS One. 2015; 10(9):e0139179. PMID: 26407179; PMCID: PMC4583281; DOI: 10.1371/journal.pone.0139179;.
     
  9. Leyme A, Marivin A, Perez-Gutierrez L, Nguyen LT, Garcia-Marcos M. Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin. J Cell Biol. 2015 Sep 28; 210(7):1165-84.View Related Profiles. PMID: 26391662; PMCID: PMC4586755; DOI: 10.1083/jcb.201506041;.
     
  10. Bhandari D, Lopez-Sanchez I, To A, Lo IC, Aznar N, Leyme A, Gupta V, Niesman I, Maddox AL, Garcia-Marcos M, Farquhar MG, Ghosh P. Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration-proliferation dichotomy. Proc Natl Acad Sci U S A. 2015 Sep 1; 112(35):E4874-83.View Related Profiles. PMID: 26286990; PMCID: PMC4568279; DOI: 10.1073/pnas.1514157112;.
     
Showing 10 of 14 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 14 publications over 7 distinct years, with a maximum of 4 publications in 2016

YearPublications
20111
20122
20141
20153
20164
20172
20181
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72 E. Concord St Silvio Conte (K)
Boston MA 02118
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