Xuemei Zhong, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Hematology & Medical Oncology

PhD, Boston University
MSc, University of Massachusetts Boston

Dr. Xuemei Zhong is an Assistant Professor of Medicine at Boston University School of Medicine. She received her bachelor’s in English and Biochemistry from the East China University of Science and Technology. Following that, she received a master’s in molecular biology from the University of Massachusetts. She then pursued her PhD in Immunology/Pathology at Boston University School of Medicine. She discovered a new B-lymphocyte population termed L2pB1 cells as an instructor, and has been studying this population of cells since then. Her areas of expertise include immunology, B-cell immunology, autoimmunity, immunohistochemistry technology, inflammatory diseases and immuno-oncology research.

Boston University
Evans Center for Interdisciplinary Biomedical Research

Associate Member
Boston University Medical Center
Boston Nutrition Obesity Research Center

Boston Medical Center

Methods Improving HIV Protein Expression: Cell Substrate and Protein Purification
08/01/2018 - 07/31/2021 (PI)
Antagen Biosciences, Inc. NIH

Anti-Diphtheria antibody expression in CHO cells
01/01/2016 - 01/31/2020 (PI)
Antagen Institute for Biomed Research CDC

In vivo study of a unique phagocytic L2pB1 B lymphocyte in diet induced obesity
07/01/2016 - 06/30/2018 (PI)

Development of a novel cell-based immune therapy usng Nanoparticles and natural IgM-producing pha…
04/15/2016 - 03/31/2018 (PI)

Role of Musculin (MSC) in the Differentiation and Maintenance of T Helper Cell Subjects
07/01/2012 - 06/30/2015 (PI)
Antagen Institute for Biomed Research

B1 B-Cells in Abdominal Obesity and Diet-Accelerated Atherosclerosis
07/01/2012 - 06/30/2014 (PI)
S1R21 AR063387-02

Role of L2pB1 Cells on Central Immune Tolerance in Systemic Lupus Erythematosus
08/01/2010 - 06/30/2013 (PI)
5R03 AR059908-03

Probing the Role of Inflammatory Cytokines on Negative Immune Regulation in Autoimmune Myocarditis
01/01/2007 - 06/30/2011 (PI)
American Heart Assoc

Role of B cell-activating factor of TNF family (BAFF) in inflammatory heart disease
06/01/2008 - 06/01/2009 (PI)
American Heart Assoc

Molecular Determinants in B1 and B2 cells
01/01/2007 - 04/30/2007 (PI)
Feinstein Institute NIH-NIAID

Showing 10 of 11 results. Show All Results


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Lee RA, Mao C, Vo H, Gao W, Zhong X. Fluorescence tagging and inducible depletion of PD-L2-expressing B-1 B cells in vivo. Ann N Y Acad Sci. 2015 Dec; 1362:77-85. PMID: 26291441; DOI: 10.1111/nyas.12865;
  2. Aprahamian TR, Zhong X, Amir S, Binder CJ, Chiang LK, Al-Riyami L, Gharakhanian R, Harnett MM, Harnett W, Rifkin IR. The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model. Int J Parasitol. 2015 Mar; 45(4):203-7.View Related Profiles. PMID: 25666929; PMCID: PMC4355381; DOI: 10.1016/j.ijpara.2014.12.006;
  3. Vo H, Chiu J, Allaimo D, Mao C, Wang Y, Gong Y, Ow H, Porter T, Zhong X. High fat diet deviates PtC-specific B1 B cell phagocytosis in obese mice. Immun Inflamm Dis. 2014 Dec; 2(4):254-61.View Related Profiles. PMID: 25866632; DOI: 10.1002/iid3.41;
  4. Zeng L, Maruyama S, Nakamura K, Parker-Duffen JL, Adham IM, Zhong X, Lee HK, Querfurth H, Walsh K. The injury-induced myokine insulin-like 6 is protective in experimental autoimmune myositis. Skelet Muscle. 2014; 4:16.View Related Profiles. PMID: 25161767; DOI: 10.1186/2044-5040-4-16;
  5. Chan LL, Zhong X, Pirani A, Lin B. A novel method for kinetic measurements of rare cell proliferation using Cellometer image-based cytometry. J Immunol Methods. 2012 Mar 30; 377(1-2):8-14. PMID: 22265885; DOI: 10.1016/j.jim.2012.01.006;
  6. Chan LL, Zhong X, Qiu J, Li PY, Lin B. Cellometer vision as an alternative to flow cytometry for cell cycle analysis, mitochondrial potential, and immunophenotyping. Cytometry A. 2011 Jul; 79(7):507-17. PMID: 21538841; DOI: 10.1002/cyto.a.21071;
  7. Zhong X, Rothstein TL. L2pB1: a new player in autoimmunity. Mol Immunol. 2011 Jun; 48(11):1292-300. PMID: 21195478; PMCID: PMC3087825; DOI: 10.1016/j.molimm.2010.12.006;
  8. Zhong X, Lau S, Bai C, Degauque N, Holodick NE, Steven SJ, Tumang J, Gao W, Rothstein TL. A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice. Arthritis Rheum. 2009 Dec; 60(12):3734-43. PMID: 19950285; PMCID: PMC2868318; DOI: 10.1002/art.25015;
  9. Holodick NE, Repetny K, Zhong X, Rothstein TL. Adult BM generates CD5+ B1 cells containing abundant N-region additions. Eur J Immunol. 2009 Sep; 39(9):2383-94. PMID: 19714574; PMCID: PMC2792924; DOI: 10.1002/eji.200838920;
  10. Ding H, Wang L, Wu X, Yan J, He Y, Ni B, Gao W, Zhong X. Blockade of B-cell-activating factor suppresses lupus-like syndrome in autoimmune BXSB mice. J Cell Mol Med. 2010 Jun; 14(6B):1717-25. PMID: 19627403; DOI: 10.1111/j.1582-4934.2009.00817.x;
Showing 10 of 17 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 17 publications over 11 distinct years, with a maximum of 4 publications in 2009

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

B cell immunology
Inflammatory Diseases
Immunohistochemistry Technology
immuno-oncology research
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650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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