Vincent Falanga, MD, FACP
Emeritus Professor
Boston University Chobanian & Avedisian School of Medicine
Dermatology

MD, Harvard Medical School
BA, College of the Holy Cross



Dr. Vincent Falanga is Emeritus Professor of Dermatology at Chobanian and Avedisian School of Medicine. A dedicated researcher, clinician, and educator, Dr. Vincent Falanga has had a longstanding relationship with the Boston University community. For the past 26 years, Dr. Falanga has been a Professor Biochemistry at the Chobanian and Avedisian School of Medicine (BUSM). In addition, he served as the Assistant Dean of Clinical and Faculty Affairs, as well as the Director of the Boston University Medical Students Ambulatory Medical Clerkship at Roger Williams Medical Center (RWMC), a research and clinical affiliate of the BUSM. From 1998 to 2013, he was the Chairman and Program Director of the Department of Dermatology at RWMC, a major affiliate of Boston University. At that Institution he was also president of the multispecialty practice group. Prior to that, Dr. Falanga held several academic appointments, including an initial one at the University of Pittsburgh School Of Medicine, and then as Professor of Dermatology and Medicine at the Miller School of Medicine at the University of Miami. A graduate of Harvard Medical School, Dr. Falanga received training in Internal Medicine and Dermatology at the University of Miami and the University of Pennsylvania, respectively. He is Board certified in both Medicine and Dermatology. In 2004, he was the President of the Wound Healing Society, the premier research organization in the world dedicated to wound healing.

Vincent Falanga’s remarkable research career began in the fields of molecular and cell biology, evolving over the years to groundbreaking human-based translational research. He made seminal contributions to the expansion and growth of single cells in low oxygen tension and to the effects and transcriptional regulation of transforming growth factor-ß 1 (TGF-ß1). Dr. Falanga later focused his efforts on human recombinant growth factors and was the first to use a recombinant growth factor (EGF) in human non-healing wounds. He showed that systemic anabolic steroids can heal the painful skin ulcers due to cryo-fibrinogenemia and that doubling the dose of systemically administered pentoxifylline will heal venous ulcers. In 1998, he was the lead author in the use of living bioengineered skin in non-healing wounds, which led to the first ever FDA approval of bioengineered skin for accelerating wound closure. In 2007, he was the first to successfully use autologous cultured bone marrow-derived mesenchymal stem cells in human chronic wounds. In 2013 Dr. Falanga moved his clinical research and basic science laboratory at the main campus of the medical school, becoming the first recipient of the "Barbara A. Gilchrest Professorship". At the same time, he became the Vice-Chair for research in the Department of Dermatology and the residency program director. In those roles Dr. Falanga spearheaded and coordinated many of the research projects related to tissue injury, repair processes, and regeneration. He also recruited junior research faculty members to the Department of Dermatology. Between 2013 and 2016 Dr. Falanga established a newly constructed Good Manufacturing Practice (GMP) facility in which he oversaw the research and development of novel treatments utilizing the therapeutic potential of stem cells in the care of chronic wounds caused by disorders ranging from diabetes to autoimmune disease. The GMP facility remains a potential research laboratory to enrich the translational capabilities of the Medical Center in Dermatology and other specialties. Up to 2016 his project with stem cells in human wounds was funded by the National Institutes of Health. Overall and throughout his scientific career, Dr. Falanga has received more than $45 million in research funding, mostly from the National Institutes of Health (NIH).

Research Professor
Boston University Chobanian & Avedisian School of Medicine
Biochemistry & Cell Biology




Treatment of Venous Ulcers with Autologous Cultured Bone Marrow Stem Cells
07/01/2013 - 09/16/2016 (PI)
NIH/National Institute of Arthritis & Musculoskeletal & Skin Diseases
5R01AR060342-06

Development of Adult Pluripotent Very Small Embryonic Like (VSEL) Stem Cells to T
09/11/2013 - 02/28/2015 (Subcontract PI)
Neostem, Inc NIH NIAMS
1R43AR062432-01A1

The use of topically applied bone-marrow derived adult mesenchymal stem cells (MCSs) for rapid wound healing
07/01/2013 - 06/30/2014 (Subcontract PI)
Neostem, Inc Dept of Defense




Title


Yr Title Project-Sub Proj Pubs
2015 Treatment of venous ulcers with autologous cultured bone marrow stem cells 5R01AR060342-06 15
2014 Treatment of venous ulcers with autologous cultured bone marrow stem cells 5R01AR060342-05 15
2013 Treatment of venous ulcers with autologous cultured bone marrow stem cells 7R01AR060342-04 15
2013 Treatment of venous ulcers with autologous cultured bone marrow stem cells 5R01AR060342-03 15
2012 Treatment of venous ulcers with autologous cultured bone marrow stem cells 5R01AR060342-02 15
2012 New Approaches to Tissue Repair 8P20GM103414-10 15
2011 NEW APPROACHES TO TISSUE REPAIR: ADMINISTRATIVE CORE 5P20RR018757-09-8350 93
2011 Treatment of venous ulcers with autologous cultured bone marrow stem cells 1R01AR060342-01A1 15
2011 New Approaches to Tissue Repair 5P20RR018757-09 93
2010 NEW APPROACHES TO TISSUE REPAIR: ADMINISTRATIVE CORE 5P20RR018757-08-7476 93
Showing 10 of 47 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Nahm WJ, de Imus G, Mathe CA, Saap L, Joseph S, Chen S, Falanga V. A case of markedly impaired wound repair with angiostatic pazopanib in a patient who had Mohs surgery for a basal cell carcinoma. SAGE Open Med Case Rep. 2023; 11:2050313X231200967. PMID: 37736143; PMCID: PMC10510339; DOI: 10.1177/2050313X231200967;
     
  2. Kida M, Fatima I, Rozhkova E, Otero-Viñas M, Wu M, Kalin JH, Cole PA, Falanga V, Alani RM, Sharov AA. Inhibition of the CoREST Repressor Complex Promotes Wound Re-Epithelialization through the Regulation of Keratinocyte Migration. J Invest Dermatol. 2024 Feb; 144(2):378-386.e2.View Related Profiles. PMID: 37633457; PMCID: PMC10790709; DOI: 10.1016/j.jid.2023.07.022;
     
  3. Falanga V. The dilemma of hard-to-heal wounds: stimulation versus energy consideration. J Wound Care. 2022 Dec 02; 31(12):1015. PMID: 36475856
     
  4. Falanga V, Isseroff RR, Soulika AM, Romanelli M, Margolis D, Kapp S, Granick M, Harding K. Chronic wounds. Nat Rev Dis Primers. 2022 Jul 21; 8(1):50. PMID: 35864102; PMCID: PMC10352385; DOI: 10.1038/s41572-022-00377-3;
     
  5. Falanga V, Grada A, Otero-Vinas M, Lin X, Yufit T, Fiore D, Carson P. Autologous Cultured Bone Marrow-Derived Mesenchymal Stem Cells in a Fibrin Spray to Treat Venous Ulcers: A Randomized Controlled Double-Blind Pilot Study. Surg Technol Int. 2022 May 19; 40:47-54. PMID: 35168289
     
  6. Otero M, Lin X, MacLauchlan S, Carson P, Falanga V. Dermal Fibroblasts from Chronic Wounds Exhibit Paradoxically Enhanced Proliferative and Migratory Activities that May be Related to the Non-Canonical Wnt Signaling Pathway. Surg Technol Int. 2021 06 28; 39:59-66.View Related Profiles. PMID: 34181242
     
  7. Obagi Z, Damiani G, Grada A, Falanga V. Principles of Wound Dressings: A Review. Surg Technol Int. 2019 11 10; 35:50-57.View Related Profiles. PMID: 31480092
     
  8. Grada A, Mervis J, Falanga V. Research Techniques Made Simple: Animal Models of Wound Healing. J Invest Dermatol. 2018 10; 138(10):2095-2105.e1.View Related Profiles. PMID: 30244718
     
  9. Ferrer-Sola M, Sureda-Vidal H, Altimiras-Roset J, Fontsere-Candell E, Gonzalez-Martinez V, Espaulella-Panicot J, Falanga V, Otero-Viñas M. Hydrosurgery as a safe and efficient debridement method in a clinical wound unit. J Wound Care. 2017 10 02; 26(10):593-599. PMID: 28976826
     
  10. Grada A, Falanga V. Cryofibrinogenemia-Induced Cutaneous Ulcers: A Review and Diagnostic Criteria. Am J Clin Dermatol. 2017 Feb; 18(1):97-104.View Related Profiles. PMID: 27734332; DOI: 10.1007/s40257-016-0228-y;
     
Showing 10 of 328 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 328 publications over 40 distinct years, with a maximum of 26 publications in 1993

YearPublications
19811
19842
19855
19865
19877
198810
198914
199011
199122
199211
199326
19948
199513
199612
19979
199817
199910
200015
200111
200216
200317
20049
20056
20068
20078
20088
20096
20104
20112
20126
20136
20143
20153
20166
20173
20181
20191
20211
20223
20232


2013 Boston University School of Medicine: Barbara A. Gilchrest Professor of Dermatology
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Stem Cells
Wound Healing
Bioengineered Skin
Fibrosis
Chronic Wounds

Available to Mentor as: (Review Mentor Role Definitions):
  • Education Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

25 Buick St
Boston MA 02215
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