Valérie Gouon-Evans, PhD, PharmD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Gastroenterology

PhD, University of Paris Vii
MS, University of Paris Vii
BS, Pierre and Marie Curie University (Paris VI)
PharmD, Université Paris 5 René Descartes

Pronouns: she/her/hers



Valerie Gouon-Evans, PharmD, PhD is an Associate Professor of Medicine in the department of Gastroenterology at the Chobanian and Avedisian School of Medicine. After completing her graduate studies in Paris, Dr. Gouon-Evans joined Dr. Pollard's Lab as a postdoctoral fellow where she studied mammary gland development and breast cancer. She then began her career as an Instructor of Gene and Cell Medicine at the Icahn School of Medicine at Mount Sinai School of Medicine in New York in the laboratory of Dr. Gordon Keller, where she pioneered protocols to efficiently generate hepatocyte-like cells from pluripotent stem cells. She quickly rose up the ranks and was promoted to Assistant Professor before arriving at Boston University. Dr. Gouon-Evans's current research interests range from liver development, regeneration, and cancer using the pluripotent stem cell platform, in vivo mouse models, and primary human tissues.

Member
Boston University
Center for Regenerative Medicine


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research


Member
Boston University
Genome Science Institute


Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




Primary hepatocyte and engineered iPSC-derived hepatocyte-like cell transplantation to treat alpha-1 antitrypsin deficiencyassociated liver disease
02/01/2023 - 01/31/2026 (Key Person / Mentor)
NIH/National Diabetes & Digestive & Kidney Diseases
1F31DK135378-01

Sexual dimorphism of acetaminophen-induced liver injury and regeneration
07/01/2021 - 10/31/2022 (Key Person / Mentor)
NIH/National Diabetes & Digestive & Kidney Diseases
5F31DK127606-02


A multi-modular approach for human pluripotent stem cell-based liver regeneration
09/15/2020 - 07/31/2024 (PI)
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
1R01DK124361-01A1

Edited stem cell-based therapy with transcript therapy for AATD-associated liver disease
07/01/2019 - 06/30/2022 (PI)
Alpha-1 Foundation

Use of Human Pluripotent Stem Cell-derived Hepatic Cells in Pediatric Liver Transplantation
07/01/2017 - 05/31/2018 (PI)
March of Dimes


Title


Yr Title Project-Sub Proj Pubs
2023 Investigation of the role of VEGFA in harnessing cholangiocyte-driven liver regeneration 5R01DK133404-02
2022 Investigation of the role of VEGFA in harnessing cholangiocyte-driven liver regeneration 1R01DK133404-01
2022 A multi-modular approach for human pluripotent stem cell-based liver regeneration 5R01DK124361-03
2021 A multi-modular approach for human pluripotent stem cell-based liver regeneration 5R01DK124361-02
2020 A multi-modular approach for human pluripotent stem cell-based liver regeneration 1R01DK124361-01A1
2014 Endothelial cells in liver development and regeneration 5R01DK087867-05 11
2013 Endothelial cells in liver development and regeneration 5R01DK087867-04 11
2012 Endothelial cells in liver development and regeneration 5R01DK087867-03 11
2011 Endothelial cells in liver development and regeneration 5R01DK087867-02 11
2010 Endothelial cells in liver development and regeneration 1R01DK087867-01 11
Showing 10 of 15 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Gouon-Evans V, Fiorotto R. Fibroblasts to hepatocytes: A nonstop flight into cell therapy for liver diseases? Hepatology. 2023 May 01; 77(5):1469-1471. PMID: 35957526
     
  2. Kim M, Rizvi F, Shin D, Gouon-Evans V. Update on Hepatobiliary Plasticity. Semin Liver Dis. 2023 Feb; 43(1):13-23.View Related Profiles. PMID: 36764306; PMCID: PMC10005859; DOI: 10.1055/s-0042-1760306;
     
  3. Smith AR, Gouon-Evans V. c-Maf: The magic wand that turns on LSEC fate. Cell Stem Cell. 2022 Apr 07; 29(4):491-493. PMID: 35395181
     
  4. Everton E, Rizvi F, Smith AR, Beattie M, Tam Y, Pardi N, Weissman D, Gouon-Evans V. Transient yet Robust Expression of Proteins in the Mouse Liver via Intravenous Injection of Lipid Nanoparticle-encapsulated Nucleoside-modified mRNA. Bio Protoc. 2021 Oct 05; 11(19):e4184.View Related Profiles. PMID: 34722830; PMCID: PMC8517647; DOI: 10.21769/BioProtoc.4184;
     
  5. Rizvi F, Everton E, Smith AR, Liu H, Osota E, Beattie M, Tam Y, Pardi N, Weissman D, Gouon-Evans V. Author Correction: Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA. Nat Commun. 2021 May 10; 12(1):2825.View Related Profiles. PMID: 33972545; PMCID: PMC8110992; DOI: 10.1038/s41467-021-23322-6;
     
  6. Rizvi F, Everton E, Smith AR, Liu H, Osota E, Beattie M, Tam Y, Pardi N, Weissman D, Gouon-Evans V. Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA. Nat Commun. 2021 01 27; 12(1):613.View Related Profiles. PMID: 33504774; PMCID: PMC7840919; DOI: 10.1038/s41467-021-20903-3;
     
  7. Han S, Tan C, Ding J, Wang J, Ma'ayan A, Gouon-Evans V. Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications. Stem Cell Res. 2018 07; 30:163-170. PMID: 29936335; DOI: 10.1016/j.scr.2018.06.004;
     
  8. Bardot E, Calderon D, Santoriello F, Han S, Cheung K, Jadhav B, Burtscher I, Artap S, Jain R, Epstein J, Lickert H, Gouon-Evans V, Sharp AJ, Dubois NC. Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential. Nat Commun. 2017 02 14; 8:14428. PMID: 28195173; PMCID: PMC5316866; DOI: 10.1038/ncomms14428;
     
  9. Goldman O, Cohen I, Gouon-Evans V. Functional Blood Progenitor Markers in Developing Human Liver Progenitors. Stem Cell Reports. 2016 08 09; 7(2):158-66. PMID: 27509132; PMCID: PMC4983080; DOI: 10.1016/j.stemcr.2016.07.008;
     
  10. Goldman O, Gouon-Evans V. Human Pluripotent Stem Cells: Myths and Future Realities for Liver Cell Therapy. Cell Stem Cell. 2016 06 02; 18(6):703-6. PMID: 27257759; DOI: 10.1016/j.stem.2016.05.019;
     
Showing 10 of 35 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 35 publications over 19 distinct years, with a maximum of 4 publications in 2011

YearPublications
20001
20011
20023
20031
20041
20063
20091
20101
20114
20121
20133
20143
20151
20163
20171
20181
20213
20221
20232

2010 Federation of American Societies for Experimental Biology (FASEB): Travel Award
2008 Federation of American Societies for Experimental Biology (FASEB): Travel Award
2007-2008 International Society for Stem Cell Research: Travel Award
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Boston MA 02118
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