Tony E. Godfrey, PhD
Boston University School of Medicine
Dept of Surgery
Other Surgery

PhD, Brunel University

Tony E. Godfrey, PhD, Associate Chair, Surgical Research and Associate Professor of Surgery, Boston University School of Medicine, earned a bachelor’s of science degree in biochemistry from Brunel University in England, followed by a doctorate in molecular biology and biochemistry, also from Brunel. He attended the University of California, San Francisco, for postdoctoral fellowships and managed UCSF’s Genome Analysis Core Facility.

Most recently, Dr. Godfrey was a Research Associate Professor in the Department of Surgery at the University of Rochester Medical Center in Rochester, NY. Prior to this he was an Associate Professor of Pathology at Mt. Sinai School of Medicine in New York, NY.

Dr. Godfrey’s research is focused on cancer genetics and molecular pathology. Research projects use state-of-the-art genetic and genomic approaches to address clinical needs in the areas of cancer diagnosis, prognosis and therapy. Currently the major focus of Dr. Godfrey’s research is on Barrett’s esophagus and esophageal adenocarcinoma; a tumor with rapidly increasing incidence in the United States and other western countries. The Godfrey lab works closely with translational research teams comprised of surgeons, pathologists and oncologists in order to develop new molecular approaches to cancer detection, staging and treatment.

Boston University School of Medicine
Computational Biomedicine

Development of diagnostic and prognostic tests for esophageal adenocarcinoma
12/16/2016 - 11/30/2021 (PI)
NIH/National Cancer Institute

Feasibility of Molecular Cytology for the Management of Barrett's Esophagus
04/21/2015 - 03/31/2018 (PI)
NIH/National Cancer Institute

Biomarkers for Esophageal cancer Progression and Prognosis
04/01/2013 - 03/31/2018 (PI)
Ontario Institute for Cancer Research Genome Canada

Evaluating the Feasibility of a Molecular Cytology Approach for Management of Patients with Barrett's Esophagus
01/15/2014 - 06/30/2016 (PI)
DeGregorio Foundation

Innovative Approach to Cancer Detection and Treatment Monitoring
04/01/2013 - 03/31/2016 (PI)
NIH/National Cancer Institute

Biomarkers for Esophageal Cancer progression and prognosis
01/01/2013 - 07/31/2015 (PI)
NIH/National Cancer Institute

Yr Title Project-Sub Proj Pubs
2019 Development of diagnostic and prognostic tests for esophageal adenocarcinoma 5R01CA208599-03
2018 Development of diagnostic and prognostic tests for esophageal adenocarcinoma 5R01CA208599-02
2017 Development of diagnostic and prognostic tests for esophageal adenocarcinoma 1R01CA208599-01A1
2016 Feasibility of Molecular Cytology for the Management of Barrett's Esophagus 5R21CA187753-02
2015 Feasibility of Molecular Cytology for the Management of Barrett's Esophagus 1R21CA187753-01A1
2014 Innovative approach to cancer detection and treatment monitoring 5R21CA172999-02 2
2013 Innovative approach to cancer detection and treatment monitoring 1R21CA172999-01 2
2012 Biomarkers for Esophageal Cancer Progression and Prognosis 5R01CA130853-05 5
2012 Biomarkers for Esophageal Cancer Progression and Prognosis 7R01CA130853-06 5
2011 Biomarkers for Esophageal Cancer Progression and Prognosis 5R01CA130853-04 5
Showing 10 of 27 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Egyud M, Sridhar P, Devaiah A, Yamada E, Saunders S, Ståhlberg A, Filges S, Krzyzanowski PM, Kalatskaya I, Jiao W, Stein LD, Jalisi S, Godfrey TE. Plasma circulating tumor DNA as a potential tool for disease monitoring in head and neck cancer. Head Neck. 2018 Dec 15.View Related Profiles. PMID: 30554450.
  2. Muñoz-Largacha JA, Gower AC, Sridhar P, Deshpande A, O'Hara CJ, Yamada E, Godfrey TE, Fernando HC, Litle VR. miRNA profiling of primary lung and head and neck squamous cell carcinomas: Addressing a diagnostic dilemma. J Thorac Cardiovasc Surg. 2017 Aug; 154(2):714-727.View Related Profiles. PMID: 28495058.
  3. Ståhlberg A, Krzyzanowski PM, Egyud M, Filges S, Stein L, Godfrey TE. Simple multiplexed PCR-based barcoding of DNA for ultrasensitive mutation detection by next-generation sequencing. Nat Protoc. 2017 Apr; 12(4):664-682. PMID: 28253235; DOI: 10.1038/nprot.2017.006;.
  4. Pang C, LaLonde A, Godfrey TE, Que J, Sun J, Wu TT, Zhou Z. Bile salt receptor TGR5 is highly expressed in esophageal adenocarcinoma and precancerous lesions with significantly worse overall survival and gender differences. Clin Exp Gastroenterol. 2017; 10:29-37. PMID: 28223834; DOI: 10.2147/CEG.S117842;.
  5. Ståhlberg A, Krzyzanowski PM, Jackson JB, Egyud M, Stein L, Godfrey TE. Simple, multiplexed, PCR-based barcoding of DNA enables sensitive mutation detection in liquid biopsies using sequencing. Nucleic Acids Res. 2016 Jun 20; 44(11):e105. PMID: 27060140; PMCID: PMC4914102; DOI: 10.1093/nar/gkw224;.
  6. Jackson JB, Choi DS, Luketich JD, Pennathur A, Ståhlberg A, Godfrey TE. Multiplex Preamplification of Serum DNA to Facilitate Reliable Detection of Extremely Rare Cancer Mutations in Circulating DNA by Digital PCR. J Mol Diagn. 2016 Mar; 18(2):235-43. PMID: 26752305; PMCID: PMC4851734; DOI: 10.1016/j.jmoldx.2015.10.004;.
  7. Ghatak S, Reveiller M, Toia L, Ivanov AI, Zhou Z, Redmond EM, Godfrey TE, Peters JH. Bile Salts at Low pH Cause Dilation of Intercellular Spaces in In Vitro Stratified Primary Esophageal Cells, Possibly by Modulating Wnt Signaling. J Gastrointest Surg. 2016 Mar; 20(3):500-9. PMID: 26715559; DOI: 10.1007/s11605-015-3062-2;.
  8. Andersson D, Akrap N, Svec D, Godfrey TE, Kubista M, Landberg G, Ståhlberg A. Properties of targeted preamplification in DNA and cDNA quantification. Expert Rev Mol Diagn. 2015; 15(8):1085-100. PMID: 26132215; DOI: 10.1586/14737159.2015.1057124;.
  9. Bandla S, Peters JH, Ruff D, Chen SM, Li CY, Song K, Thoms K, Litle VR, Watson T, Chapurin N, Lada M, Pennathur A, Luketich JD, Peterson D, Dulak A, Lin L, Bass A, Beer DG, Godfrey TE, Zhou Z. Comparison of cancer-associated genetic abnormalities in columnar-lined esophagus tissues with and without goblet cells. Ann Surg. 2014 Jul; 260(1):72-80.View Related Profiles. PMID: 24509200; PMCID: PMC4047149; DOI: 10.1097/SLA.0000000000000424;.
  10. Zhou Z, Xia Y, Bandla S, Zakharov V, Wu S, Peters J, Godfrey TE, Sun J. Vitamin D receptor is highly expressed in precancerous lesions and esophageal adenocarcinoma with significant sex difference. Hum Pathol. 2014 Aug; 45(8):1744-51. PMID: 24951052; DOI: 10.1016/j.humpath.2014.02.029;.
Showing 10 of 77 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 77 publications over 22 distinct years, with a maximum of 11 publications in 2005

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Barrett’s Esophagus
Cancer Genomics
Esophageal Adenocarcinoma
Lung Cancer
Molecular Diagnostics
Translational cancer research

Available to Mentor as: (Review Mentor Role Definitions):
  • Research / Scholarly Mentor
Contact for Mentoring:

700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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