Lawrence Ziegler | Profiles RNS

Lawrence D. Ziegler, PhD

Emeritus Professor

Boston University College of Arts and Sciences

Chemistry

PhD, Cornell University
MS, Cornell University
BS, Stony Brook University

Websites

	Chemistry
	Public Relations
	BU Photonics Center
	BUnano
	Google Scholar
	Research Gate

ORCID : 0000-0002-3026-8986

Professor Larry Ziegler is Chair of the Chemistry Department at Boston University. He and his research group have received continued support from the NSF ($450K over 3 years) to use cutting edge spectroscopic techniques to advance understanding of supercritical fluids (SCFs) as a medium for chemical activity. Using ultrafast vibrational or rotational spectroscopic techniques, he and his team of researchers study the femtosecond to picosecond solvation dynamics of a range of SCF solutions as a function of density for isotherms close to the critical temperature.

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Chair
Boston University College of Arts and Sciences
Chemistry

BU Research

Ultrafast 2DIR studies of dynamics in dense gas and supercritical fluid solutions
08/01/2021 - 07/31/2024 (PI)
National Science Foundation
CHE-2102427

Body fluid analysis detection and identification by surface enhanced Raman spectroscopy for forensic scientists
01/01/2019 - 12/31/2021 (PI)
Department of Justice

Plasmonically Enhanced Stimulated Coherent Spectroscopy
07/15/2016 - 06/30/2019 (PI)
National Science Foundation
CHE-1609952

Body Fluid Analysis by Surface Enhanced Raman Spectroscopy for Forensic Applications
01/01/2015 - 03/31/2017 (PI)
Department of Justice/NIJ

I/UCRC Collaborative Research
07/01/2011 - 02/28/2017 (Co-Investigator of Sub-Project / SP)
I/UCRC: Industry Memberships

Ultrafast Dynamics of Supercritical Fluids
07/15/2012 - 06/30/2016 (PI)
National Science Foundation
CHE-1152797

Bacterial Drug Susceptibility Identification by Surface Enhanced Raman Microscopy
07/01/2010 - 12/31/2015 (Subcontract PI)
Fraunhofer USA NIH NIAID
5R01AI090815-05

EFFECTS OF IMMEDIATE BIOCHEMICAL ENVIRONMENTS ON THE STRUCTURE AND FUNCTION OF AORTIC ELASTIN
05/01/2011 - 04/30/2015 (Co-Investigator)
National Science Foundation
CMMI-1100791

ASTRAZENECA GRADUATE FELLOWSHIP IN ORGANIC CHEMISTRY
06/03/2013 - 06/02/2014 (PI)
AstraZeneca

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Töpfer K, Koner D, Erramilli S, Ziegler LD, Meuwly M. Molecular-level understanding of the rovibrational spectra of N2O in gaseous, supercritical, and liquid SF6 and Xe. J Chem Phys. 2023 Apr 14; 158(14):144302. PMID: 37061478

Suarez C, Premasiri WR, Ingraham H, Brodeur AN, Ziegler LD. Ultra-sensitive, rapid detection of dried bloodstains by surface enhanced Raman scattering on Ag substrates. Talanta. 2023 Jul 01; 259:124535.View Related Profiles.

Brodeur, Amy
Ziegler, Lawrence

PMID: 37054622

Paulson AE, Premasiri WR, Ziegler LD, Lee YJ. Use of Nanoparticle Decorated Surface-Enhanced Raman Scattering Active Sol-Gel Substrates for SALDI-MS Analysis. J Am Soc Mass Spectrom. 2023 Feb 01; 34(2):273-278. PMID: 36594588

Rotondaro MC, Jain A, Erramilli S, Ziegler LD. Ultrafast 2DIR comparison of rotational energy transfer, isolated binary collision breakdown, and near critical fluctuations in Xe and SF6 solutions. J Chem Phys. 2022 Nov 07; 157(17):174305. PMID: 36347695

Sheinman M, Erramilli S, Ziegler L, Hong MK, Mertz J. Flatfield ultrafast imaging with single-shot non-synchronous array photography. Opt Lett. 2022 Feb 01; 47(3):577-580.View Related Profiles.

Mertz, Jerome
Ziegler, Lawrence

PMID: 35103680

Mandal A, Ziegler LD. Vibrational line shape effects in plasmon-enhanced stimulated Raman spectroscopies. J Chem Phys. 2021 Nov 21; 155(19):194701. PMID: 34800946

Reese T, Suarez C, Premasiri WR, Shaine ML, Ingraham H, Brodeur AN, Ziegler LD. Surface enhanced Raman scattering specificity for detection and identification of dried bloodstains. Forensic Sci Int. 2021 Nov; 328:111000.View Related Profiles.

Brodeur, Amy
Ziegler, Lawrence

PMID: 34564021

Rajagopal R, Hong MK, Ziegler LD, Erramilli S, Narayan O. Conjugate Acid-Base Interaction Driven Phase Transition at a 2D Air-Water Interface. J Phys Chem B. 2021 06 17; 125(23):6330-6337. PMID: 34076448

Shaine ML, Premasiri WR, Ingraham HM, Andino R, Lemler P, Brodeur AN, Ziegler LD. Surface enhanced Raman scattering for robust, sensitive detection and confirmatory identification of dried bloodstains. Analyst. 2020 Sep 14; 145(18):6097-6110.View Related Profiles.

Brodeur, Amy
Ziegler, Lawrence

PMID: 32840504

Andino RS, Liu J, Miller CM, Chen X, Devlin SW, Hong MK, Rajagopal R, Erramilli S, Ziegler LD. Anomalous pH-Dependent Enhancement of p-Methyl Benzoic Acid Sum-Frequency Intensities: Cooperative Surface Adsorption Effects. J Phys Chem A. 2020 Apr 23; 124(16):3064-3076. PMID: 32212703

Showing 10 of 49 results. Show More

Zong C, Premasiri R, Lin H, Huang Y, Zhang C, Yang C, Ren B, Ziegler LD, Cheng JX. Plasmon-enhanced stimulated Raman scattering microscopy with single-molecule detection sensitivity. Nat Commun. 2019 11 21; 10(1):5318.View Related Profiles.

Cheng, Ji-Xin
Ziegler, Lawrence

PMID: 31754221; PMCID: PMC6872561; DOI: 10.1038/s41467-019-13230-1;

Ng Pack G, Rotondaro MC, Shah PP, Mandal A, Erramilli S, Ziegler LD. Two-dimensional infrared spectroscopy from the gas to liquid phase: density dependent J-scrambling, vibrational relaxation, and the onset of liquid character. Phys Chem Chem Phys. 2019 Oct 14; 21(38):21249-21261. PMID: 31538165

Chen Y, Premasiri WR, Ziegler LD. Surface enhanced Raman spectroscopy of Chlamydia trachomatis and Neisseria gonorrhoeae for diagnostics, and extra-cellular metabolomics and biochemical monitoring. Sci Rep. 2018 03 26; 8(1):5163. PMID: 29581560; PMCID: PMC5980109; DOI: 10.1038/s41598-018-23562-5;

Mandal A, Ng Pack G, Shah PP, Erramilli S, Ziegler LD. Ultrafast Two-Dimensional Infrared Spectroscopy of a Quasifree Rotor: J Scrambling and Perfectly Anticorrelated Cross Peaks. Phys Rev Lett. 2018 Mar 09; 120(10):103401. PMID: 29570323

Chen J, Liu J, Tevis ID, Andino RS, Miller CM, Ziegler LD, Chen X, Thuo MM. Spectroscopic evidence for the origin of odd-even effects in self-assembled monolayers and effects of substrate roughness. Phys Chem Chem Phys. 2017 Mar 08; 19(10):6989-6995. PMID: 28244512; DOI: 10.1039/c6cp07580k;

Premasiri WR, Chen Y, Williamson PM, Bandarage DC, Pyles C, Ziegler LD. Rapid urinary tract infection diagnostics by surface-enhanced Raman spectroscopy (SERS): identification and antibiotic susceptibilities. Anal Bioanal Chem. 2017 Apr; 409(11):3043-3054. PMID: 28235996; DOI: 10.1007/s00216-017-0244-7;

Shattuck J, Shah P, Erramilli S, Ziegler LD. Structure Making and Breaking Effects of Cations in Aqueous Solution: Nitrous Oxide Pump-Probe Measurements. J Phys Chem B. 2016; 120(40):10569-10580. PMID: 27668810

Boardman AK, Wong WS, Premasiri WR, Ziegler LD, Lee JC, Miljkovic M, Klapperich CM, Sharon A, Sauer-Budge AF. Rapid Detection of Bacteria from Blood with Surface-Enhanced Raman Spectroscopy. Anal Chem. 2016 08 16; 88(16):8026-35.View Related Profiles.

Boardman, Anna
Klapperich, Catherine
Ziegler, Lawrence

PMID: 27429301; PMCID: PMC4988670; DOI: 10.1021/acs.analchem.6b01273;

Premasiri WR, Lee JC, Sauer-Budge A, Théberge R, Costello CE, Ziegler LD. The biochemical origins of the surface-enhanced Raman spectra of bacteria: a metabolomics profiling by SERS. Anal Bioanal Chem. 2016 Jul; 408(17):4631-47.View Related Profiles.

Costello, Catherine
Ziegler, Lawrence
Theberge, Roger

PMID: 27100230; PMCID: PMC4911336; DOI: 10.1007/s00216-016-9540-x;

Mertiri A, Altug H, Hong MK, Mehta P, Mertz J, Ziegler LD, Erramilli S. Nonlinear Midinfrared Photothermal Spectroscopy Using Zharov Splitting and Quantum Cascade Lasers. ACS Photonics. 2014 Aug 20; 1(8):696-702.View Related Profiles.

Mertz, Jerome
Ziegler, Lawrence

PMID: 25541620; PMCID: PMC4270413; DOI: 10.1021/ph500114h;

Lemler P, Premasiri WR, DelMonaco A, Ziegler LD. NIR Raman spectra of whole human blood: effects of laser-induced and in vitro hemoglobin denaturation. Anal Bioanal Chem. 2014 Jan; 406(1):193-200. PMID: 24162820; PMCID: PMC3882123; DOI: 10.1007/s00216-013-7427-7;

Shattuck JT, Schneck JR, Chieffo LR, Erramilli S, Ziegler LD. Dispersed three-pulse infrared photon echoes of nitrous oxide in water and octanol. J Phys Chem B. 2013 Dec 12; 117(49):15774-85. PMID: 23941277; DOI: 10.1021/jp4065533;

Saute B, Premasiri R, Ziegler L, Narayanan R. Gold nanorods as surface enhanced Raman spectroscopy substrates for sensitive and selective detection of ultra-low levels of dithiocarbamate pesticides. Analyst. 2012 Nov 7; 137(21):5082-7. PMID: 22977883; DOI: 10.1039/c2an36047k;

Premasiri WR, Lee JC, Ziegler LD. Surface-enhanced Raman scattering of whole human blood, blood plasma, and red blood cells: cellular processes and bioanalytical sensing. J Phys Chem B. 2012 Aug 9; 116(31):9376-86.View Related Profiles.

Lee, John Cho
Ziegler, Lawrence

PMID: 22780445; PMCID: PMC3704210; DOI: 10.1021/jp304932g;

Premasiri WR, Sauer-Budge AF, Lee JC, Klapperich CM, Ziegler LD. Rapid bacterial diagnostics via surface enhanced Raman microscopy. Spectroscopy (Springf). 2012 Jun 01; 27(6):s8-31.View Related Profiles.

Klapperich, Catherine
Ziegler, Lawrence

PMID: 24371371; PMCID: PMC3872130

Harrah DM, Schneck JR, Green AA, Hersam MC, Ziegler LD, Swan AK. Intensity-dependent exciton dynamics of (6,5) single-walled carbon nanotubes: momentum selection rules, diffusion, and nonlinear interactions. ACS Nano. 2011 Dec 27; 5(12):9898-906.View Related Profiles.

Green, Alexander
Ziegler, Lawrence

PMID: 22077149; DOI: 10.1021/nn203604v;

Premasiri WR, Gebregziabher Y, Ziegler LD. On the difference between surface-enhanced raman scattering (SERS) spectra of cell growth media and whole bacterial cells. Appl Spectrosc. 2011 May; 65(5):493-9. PMID: 21513591; PMCID: PMC3692357; DOI: 10.1366/10-06173;

Schneck JR, Walsh AG, Green AA, Hersam MC, Ziegler LD, Swan AK. Electron correlation effects on the femtosecond dephasing dynamics of E22 excitons in (6,5) carbon nanotubes. J Phys Chem A. 2011 Apr 28; 115(16):3917-23.View Related Profiles.

Green, Alexander
Ziegler, Lawrence

PMID: 21241060; DOI: 10.1021/jp108345t;

Zhang JY, Do J, Premasiri WR, Ziegler LD, Klapperich CM. Rapid point-of-care concentration of bacteria in a disposable microfluidic device using meniscus dragging effect. Lab Chip. 2010 Dec 7; 10(23):3265-70.View Related Profiles.

Klapperich, Catherine
Ziegler, Lawrence

PMID: 20938505; PMCID: PMC4452279; DOI: 10.1039/c0lc00051e;

Gopinath A, Boriskina SV, Premasiri WR, Ziegler L, Reinhard BM, Dal Negro L. Plasmonic nanogalaxies: multiscale aperiodic arrays for surface-enhanced Raman sensing. Nano Lett. 2009 Nov; 9(11):3922-9.View Related Profiles.

Reinhard, Bjorn
Ziegler, Lawrence

PMID: 19754067; DOI: 10.1021/nl902134r;

Peng J, Castonguay TC, Coker DF, Ziegler LD. Ultrafast H2 and D2 rotational Raman responses in near critical CO2: an experimental and theoretical study of anisotropic solvation dynamics. J Chem Phys. 2009 Aug 7; 131(5):054501.View Related Profiles.

Coker, David
Ziegler, Lawrence

PMID: 19673568; DOI: 10.1063/1.3186732;

Yan B, Thubagere A, Premasiri WR, Ziegler LD, Dal Negro L, Reinhard BM. Engineered SERS substrates with multiscale signal enhancement: nanoparticle cluster arrays. ACS Nano. 2009 May 26; 3(5):1190-202.View Related Profiles.

Reinhard, Bjorn
Ziegler, Lawrence

PMID: 19354266; DOI: 10.1021/nn800836f;

Patel IS, Premasiri WR, Moir DT, Ziegler LD. Barcoding bacterial cells: A SERS based methodology for pathogen identification. J Raman Spectrosc. 2008 Nov; 39(11):1660-1672. PMID: 19714262; PMCID: PMC2732026; DOI: 10.1002/jrs.2064;

Chieffo LR, Shattuck JT, Pinnick E, Amsden JJ, Hong MK, Wang F, Erramilli S, Ziegler LD. Nitrous oxide vibrational energy relaxation is a probe of interfacial water in lipid bilayers. J Phys Chem B. 2008 Oct 9; 112(40):12776-82. PMID: 18793010; DOI: 10.1021/jp8012283;

Peng J, Ziegler LD. Optical heterodyne detected accumulated acoustic grating responses in near supercritical fluids. J Phys Chem A. 2007 Dec 27; 111(51):13457-65. PMID: 18052050

Amsden JJ, Kralj JM, Chieffo LR, Wang X, Erramilli S, Spudich EN, Spudich JL, Ziegler LD, Rothschild KJ. Subpicosecond protein backbone changes detected during the green-absorbing proteorhodopsin primary photoreaction. J Phys Chem B. 2007 Oct 11; 111(40):11824-31. PMID: 17880126

Premasiri WR, Moir DT, Klempner MS, Krieger N, Jones G, Ziegler LD. Characterization of the surface enhanced raman scattering (SERS) of bacteria. J Phys Chem B. 2005 Jan 13; 109(1):312-20. PMID: 16851017

Kaufman LJ, Heo J, Ziegler LD, Fleming GR. Heterodyne-detected fifth-order nonresonant Raman scattering from room temperature CS2. Phys Rev Lett. 2002 May 20; 88(20):207402. PMID: 12005604; DOI: 10.1103/PhysRevLett.88.207402;

Ziegler LD, Hudson B, Strommen DP, Peticolas WL. Resonance Raman spectra of mononucleotides obtained with 266 and 213 nm ultraviolet radiation. Biopolymers. 1984 Oct; 23(10):2067-81. PMID: 6498292; DOI: 10.1002/bip.360231017;

Ziegler LD, Hudson BS. Resonance Raman Scattering of Benzene and Benzene-d6 with 212.8 nm Excitation. J. Chem. Phys. 1981; 74(982).
Ziegler LD, Hudson BS. The Thermal Blooming Spectrum of Liquid Benzene in the Near Ultraviolet. Chem. Phys. Lett. 1980; 71(113).
Ziegler LD, Hudson BS. Tuning Ranges of 266 nm Pumped Dyes in the Near UV. Optics Commun. 1980; 32(119).
Ziegler LD, Albrecht AC. Preresonance Raman Scattering of Overtones: The Scattering of Two Overtones of Benzene in the Ultraviolet. J. Raman Spectrosc. 1979; 8(73).
Ziegler LD, Albrecht AC. Ultraviolet Preresonance Raman Scattering of Benzene Derivatives. Part I: Excitation Profiles for Fundamentals. J. Chem Phys. 1979; 70(2634).
Ziegler LD, Albrecht AC. Ultraviolet Preresonance Raman Scattering of Benzene Derivatives. Part II: Antiresonance Effects for Vibronically Active Modes. J. Chem Phys. 1979; 70(2344).
Korenowski G, Ziegler LD, Albrecht AC. Calculations of Resonance Raman Cross Sections in Forbidden Electronic Transitions: Scattering of the 992 cm-1 Mode in the 1B2u Band of Benzene. J. Chem Phys. 1978; 68(1248).
Ziegler LD, Albrecht AC. Raman Scattering of Benzene in the Ultraviolet. J. Chem Phys. 1977; 67(2753).
Ziegler LD, Albrecht AC. Vibronic Calculations in Benzene by CNDO/S. J. Chem Phys. 1974; 60(3558).
Johnson PM, Ziegler LD. Radiational Deuterium Effect in the Triplet-Singlet Transition of Benzene. J. Chem. Phys. 1972; 56(2169).

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 42 publications over 21 distinct years, with a maximum of 3 publications in 2009 and 2011 and 2012 and 2016 and 2021 and 2023