Karen R. Bottenfield, PhD
Postdoctoral Associate
Boston University Chobanian & Avedisian School of Medicine
Dept of Anatomy & Neurobiology




Dr. Bottenfield is a postdoctoral associate in the Laboratory of Interventions for Cortical Injury and Cognitive Decline and the Laboratory of Cognitive Neurobiology. She received her B.A. in anthropology from Eastern Washington University, followed by her M.S. in Forensic Anthropology and a Ph.D. in Anatomy and Neurobiology from Boston University School of Medicine. Her doctoral research evaluated Glial Growth Factor 2 as a treatment in a monkey model of cortical injury under the mentorship of Dr. Tara Moore.

Currently, Dr. Bottenfield is continuing a portion of her doctoral research focused on the optimization and use of biorthogonal molecules and Click Chemistry to label and quantify newly synthesized myelin in the rhesus monkey brain, which offers a novel new method to assess age-related changes in myelination and remyelination following brain injury. She is also investigating task-related activation patterns in rhesus monkey models of cortical injury and aging by quantifying the expression of the immediate early gene, c-Fos. This will lead to additional analyses of regional cell type expression and an evaluation of relationships with task performance. In addition, Dr. Bottenfield is learning electrophysiology methods and contributing to analyses of injury-related pathology of pyramidal neurons in collaboration with the Laboratory of Neural Circuits and Ultrastructure.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Karen R. Bottenfield. Glial Growth Factor 2 as a Treatment in a Monkey Model of Cortical Injury. Boston. 2022. View Publication
  2. Bottenfield KR, Bowley BGE, Pessina MA, Medalla M, Rosene DL, Moore TL. Sex differences in recovery of motor function in a rhesus monkey model of cortical injury. Biol Sex Differ. 2021 10 09; 12(1):54.View Related Profiles. PMID: 34627376; PMCID: PMC8502310; DOI: 10.1186/s13293-021-00398-9;
     
  3. Karen R. Bottenfield, Tara L. Moore, Farzad Mortazavi, Douglas Rosene . Optimization of Propargylcholine to Label Newly Synthesized Myelin in the Rhesus Monkey Brain. 2020; 34(S1):1-1. View Publication

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 3 publications over 3 distinct years, with a maximum of 1 publications in 2020 and 2021 and 2022

YearPublications
20201
20211
20221

2021 Boston University: Boston University Women Graduates’ Club Scholarship ($3800)
2020 Boston University: Boston University Women Graduates’ Club Scholarship ($3800)
2013 Boston University: Levine Scholar, Ruth and Martin Levine Scholarship Fund in Graduate Medical Education ($5000)
Contact for Mentoring:

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