Kamal Sen | Profiles RNS

Kamal Sen, PhD

Associate Professor

Boston University College of Engineering

Biomedical Engineering

PhD, Brandeis University

Websites

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	ResearchGate
	BU Center for Systems Neuroscience

Kamal Sen is an associate professor at the Hearing Research Center in the department of biomedical engineering at Boston University. His laboratory uses an integrative approach to investigate the neural coding of natural sounds in the auditory system, with a focus on auditory cortex. Electrophysiological techniques are used to record neural responses from hierarchical stages of auditory processing. Theoretical methods from areas such as statistical signal processing, systems theory, probability theory, information theory and pattern recognition are applied to characterize how neurons in the brain encode natural sounds. Computational models are constructed to understand the processing of natural sounds both at the single neuron and the network level, to model neural selectivity and discrimination, and to explore the role of learning in shaping the neural code. A major focus of the laboratory over the last decade has been to investigate cortical substrates for solving the Cocktail Party Problem.

BU Research
NIH RePORTER Research

NCS-FR: Engineering Brain Circuits for Complex Scene Analysis
09/01/2023 - 08/31/2028 (Multi-PI)
PI: Kamal Sen, PhD
National Science Foundation
SMA-2319321

Investigating Auditory Scene Analysis in Humans with Wearable fNIRS and EEG
01/01/2023 - 12/31/2023 (PI)
American Hearing Research Foundation

NCS-FO: Unraveling Cortical Circuits for Auditory Scene Analysis
10/01/2018 - 09/30/2022 (Multi-PI)
PI: Kamal Sen, PhD
National Science Foundation
IIS-1835270

Cortical Spatial Processing for Solving the Cocktail Party Problem
05/15/2019 - 03/31/2021 (Multi-PI)
PI: Kamal Sen, PhD
NIH/National Institute of Neurological Disorders & Stroke
1R34NS111742-01

Billing Agreement for Yaqing Su (Continuation)
09/02/2018 - 06/30/2019 (Subcontract PI)
Massachusetts Eye and Ear Infirmary & Physician Staff, Inc. NIH NIDCD
5R01DC002258-25

Billing Agreement for Yaqing Su
09/02/2018 - 04/28/2019 (Subcontract PI)
Massachusetts Eye and Ear Infirmary & Physician Staff, Inc. NIH NIDCD
2R01DC002258-21

Billing Agreement for Yaqing Su
10/02/2017 - 09/02/2018 (Subcontract PI)
Massachusetts Eye and Ear Infirmary & Physician Staff, Inc. NIH NIDCD
5R01DC002258-22

Billing Agreement for Yaqing Su
09/01/2015 - 08/31/2016 (Subcontract PI)
Massachusetts Eye and Ear Infirmary & Physician Staff, Inc. NIH NIDCD
2R01DC002258-21

Billing Agreement for Yaqing Su
09/01/2014 - 08/31/2015 (PI)
Massachusetts Eye and Ear Infirmary & Physician Staff, Inc.

Title

Yr	Title	Project-Sub Proj	Pubs
2019	Cortical Spatial Processing for Solving the Cocktail Party Problem	1R34NS111742-01
2010	Auditory Cortical Processing of Communication Sounds	5R01DC007610-05	15
2009	Auditory Cortical Processing of Communication Sounds	5R01DC007610-04	15
2008	Auditory Cortical Processing of Communication Sounds	5R01DC007610-03	15
2007	Auditory Cortical Processing of Communication Sounds	5R01DC007610-02	15
2006	Auditory Cortical Processing of Communication Sounds	1R01DC007610-01A1	15
2002	AUDITORY PROCESSING OF NATURAL SOUNDS	5F32DC000468-02
2001	AUDITORY PROCESSING OF NATURAL SOUNDS	1F32DC000468-01

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Chou KF, Sen K. AIM: A network model of attention in auditory cortex. PLoS Comput Biol. 2021 08; 17(8):e1009356. PMID: 34449761; PMCID: PMC8462696; DOI: 10.1371/journal.pcbi.1009356;

Sethi HS, Sen KK, Agrawal A, Sharawat A, Kumar BA. Ultrasonography: An Unchartered Modality in the Current Pandemic - A Study among Patients Admitted in the COVID-19 Intensive Care Unit. J Med Ultrasound. 2021 Jan-Mar; 29(1):15-21. PMID: 34084711; PMCID: PMC8081098; DOI: 10.4103/JMU.JMU_147_20;

Agrawal A, Mohanty SS, Sen KK. Emphysematous epididymo-orchitis: An unusual case report. Ultrasound. 2021 Aug; 29(3):199-202. PMID: 34567233; PMCID: PMC8366214; DOI: 10.1177/1742271X20977040;

Raman S, Mukherjee N, Dash K, Sen KK. Multiple intracranial cryptococcomas in an immunocompetent patient with pulmonary involvement. Indian J Pathol Microbiol. 2020 Jul-Sep; 63(3):453-455. PMID: 32769338; DOI: 10.4103/IJPM.IJPM_331_19;

Mehta R, Dhruv S, Kaushik V, Sen KK, Khan NS, Abhishek A, Dixit AK, Tripathi VN. A comparative study of antibacterial and antifungal activities of extracts from four indigenous plants. Bioinformation. 2020; 16(3):267-273. PMID: 32308269; PMCID: PMC7147494; DOI: 10.6026/97320630016267;

Tandey R, Chouhan KBS, Sen KK, Mehta R, Dubey A, Das R, Saha P, Mandal V. Physiological and biochemical responses of Amaranthus cruentus to polycyclic aromatic hydrocarbon pollution caused by thermal power units. Environ Sci Pollut Res Int. 2020 May; 27(13):14790-14806. PMID: 32056096; DOI: 10.1007/s11356-020-07971-6;

Chou KF, Dong J, Colburn HS, Sen K. A Physiologically Inspired Model for Solving the Cocktail Party Problem. J Assoc Res Otolaryngol. 2019 12; 20(6):579-593. PMID: 31392449; PMCID: PMC6889086; DOI: 10.1007/s10162-019-00732-4;

Swain B, Sahoo RK, Sen KK, G MK, Parihar SS, Dubey R. Evaluation of intrahepatic and extrahepatic biliary tree anatomy and its variation by magnetic resonance cholangiopancreatography in Odisha population: a retrospective study. Anat Cell Biol. 2020 Mar; 53(1):8-14. PMID: 32274243; PMCID: PMC7118263; DOI: 10.5115/acb.19.177;

James NM, Gritton HJ, Kopell N, Sen K, Han X. Muscarinic receptors regulate auditory and prefrontal cortical communication during auditory processing. Neuropharmacology. 2019 01; 144:155-171.View Related Profiles.

Sen, Kamal
Kopell, Nancy
Han, Xue

PMID: 30352212; PMCID: PMC6400225; DOI: 10.1016/j.neuropharm.2018.10.027;

Mandal V, Chouhan KBS, Tandey R, Sen KK, Kala HK, Mehta R. Critical analysis and mapping of research trends and impact assessment of polyaromatic hydrocarbon accumulation in leaves: let history tell the future. Environ Sci Pollut Res Int. 2018 Aug; 25(23):22464-22474. PMID: 29938381; DOI: 10.1007/s11356-018-2578-x;

Showing 10 of 38 results. Show More

Das SK, Shetty SP, Sen KK. A Novel Triage Tool: Optic Nerve Sheath Diameter in Traumatic Brain Injury and its Correlation to Rotterdam Computed Tomography (CT) Scoring. Pol J Radiol. 2017; 82:240-243. PMID: 28533826; PMCID: PMC5419089; DOI: 10.12659/PJR.900196;

von Trapp G, Buran BN, Sen K, Semple MN, Sanes DH. A Decline in Response Variability Improves Neural Signal Detection during Auditory Task Performance. J Neurosci. 2016 10 26; 36(43):11097-11106. PMID: 27798189; PMCID: PMC5098844; DOI: 10.1523/JNEUROSCI.1302-16.2016;

Sloas DC, Zhuo R, Xue H, Chambers AR, Kolaczyk E, Polley DB, Sen K. Interactions across Multiple Stimulus Dimensions in Primary Auditory Cortex. eNeuro. 2016 Jul-Aug; 3(4). PMID: 27622211; PMCID: PMC5008244; DOI: 10.1523/ENEURO.0124-16.2016;

Dong J, Colburn HS, Sen K. Cortical Transformation of Spatial Processing for Solving the Cocktail Party Problem: A Computational Model(1,2,3). eNeuro. 2016 Jan-Feb; 3(1). PMID: 26866056; PMCID: PMC4745179; DOI: 10.1523/ENEURO.0086-15.2015;

Caras ML, Sen K, Rubel EW, Brenowitz EA. Seasonal plasticity of precise spike timing in the avian auditory system. J Neurosci. 2015 Feb 25; 35(8):3431-45. PMID: 25716843; PMCID: PMC4339354; DOI: 10.1523/JNEUROSCI.3407-14.2015;

Pandey S, Shetty SA, Janarthanan K, Balalakshmoji D, Sen KK, Leelakrishnan V. Pancreatico-pleural and bronchial fistulae and associated pseudocysts: case series. JOP. 2014 Sep 28; 15(5):478-84. PMID: 25262716; DOI: 10.6092/1590-8577/2804;

Chambers AR, Hancock KE, Sen K, Polley DB. Online stimulus optimization rapidly reveals multidimensional selectivity in auditory cortical neurons. J Neurosci. 2014 Jul 02; 34(27):8963-75. PMID: 24990917; PMCID: PMC4078078; DOI: 10.1523/JNEUROSCI.0260-14.2014;

Maddox RK, Sen K, Billimoria CP. Auditory forebrain neurons track temporal features of time-warped natural stimuli. J Assoc Res Otolaryngol. 2014 Feb; 15(1):131-8. PMID: 24129604; PMCID: PMC3901856; DOI: 10.1007/s10162-013-0418-8;

Sen KK, Gunasekaran K, Kanagaraj V. Imaging in Lhermitte: Duclos disease. South Asian J Cancer. 2013 Jul; 2(3):131. PMID: 24455585; PMCID: PMC3892528; DOI: 10.4103/2278-330X.114114;

Sen KK, Balasubramaniam D, Kanagaraj V. Magnetic resonance imaging in obstructive Müllerian anomalies. J Hum Reprod Sci. 2013 Apr; 6(2):162-4. PMID: 24082660; PMCID: PMC3778608; DOI: 10.4103/0974-1208.117167;

Maddox RK, Billimoria CP, Perrone BP, Shinn-Cunningham BG, Sen K. Competing sound sources reveal spatial effects in cortical processing. PLoS Biol. 2012; 10(5):e1001319. PMID: 22563301; PMCID: PMC3341327; DOI: 10.1371/journal.pbio.1001319;

Larson E, Maddox RK, Perrone BP, Sen K, Billimoria CP. Neuron-specific stimulus masking reveals interference in spike timing at the cortical level. J Assoc Res Otolaryngol. 2012 Feb; 13(1):81-9. PMID: 21964794; PMCID: PMC3254720; DOI: 10.1007/s10162-011-0292-1;

Larson E, Perrone BP, Sen K, Billimoria CP. A robust and biologically plausible spike pattern recognition network. J Neurosci. 2010 Nov 17; 30(46):15566-72. PMID: 21084611; PMCID: PMC2997616; DOI: 10.1523/JNEUROSCI.3672-10.2010;

Lee S, Sen K, Kopell N. Cortical gamma rhythms modulate NMDAR-mediated spike timing dependent plasticity in a biophysical model. PLoS Comput Biol. 2009 Dec; 5(12):e1000602.View Related Profiles.

Sen, Kamal
Kopell, Nancy

PMID: 20011119; PMCID: PMC2782132; DOI: 10.1371/journal.pcbi.1000602;

Dent ML, McClaine EM, Best V, Ozmeral E, Narayan R, Gallun FJ, Sen K, Shinn-Cunningham BG. Spatial unmasking of birdsong in zebra finches (Taeniopygia guttata) and budgerigars (Melopsittacus undulatus). J Comp Psychol. 2009 Nov; 123(4):357-67. PMID: 19929104; PMCID: PMC2784650; DOI: 10.1037/a0016898;

Graña GD, Billimoria CP, Sen K. Analyzing variability in neural responses to complex natural sounds in the awake songbird. J Neurophysiol. 2009 Jun; 101(6):3147-57. PMID: 19357333; PMCID: PMC2694111; DOI: 10.1152/jn.90917.2008;

Greene G, Barrett DG, Sen K, Houghton C. Sparse coding of birdsong and receptive field structure in songbirds. Network. 2009; 20(3):162-77. PMID: 19731147; PMCID: PMC2794046; DOI: 10.1080/09548980903108267;

Larson E, Billimoria CP, Sen K. A biologically plausible computational model for auditory object recognition. J Neurophysiol. 2009 Jan; 101(1):323-31. PMID: 18987124; PMCID: PMC2637019; DOI: 10.1152/jn.90664.2008;

Billimoria CP, Kraus BJ, Narayan R, Maddox RK, Sen K. Invariance and sensitivity to intensity in neural discrimination of natural sounds. J Neurosci. 2008 Jun 18; 28(25):6304-8. PMID: 18562600; PMCID: PMC2730838; DOI: 10.1523/JNEUROSCI.0961-08.2008;

Houghton C, Sen K. A new multineuron spike train metric. Neural Comput. 2008 Jun; 20(6):1495-511. PMID: 18194108; PMCID: PMC2782407; DOI: 10.1162/neco.2007.10-06-350;

Shamir M, Sen K, Colburn HS. Temporal coding of time-varying stimuli. Neural Comput. 2007 Dec; 19(12):3239-61. PMID: 17970652; DOI: 10.1162/neco.2007.19.12.3239;

Narayan R, Best V, Ozmeral E, McClaine E, Dent M, Shinn-Cunningham B, Sen K. Cortical interference effects in the cocktail party problem. Nat Neurosci. 2007 Dec; 10(12):1601-7. PMID: 17994016; DOI: 10.1038/nn2009;

Wang L, Narayan R, Graña G, Shamir M, Sen K. Cortical discrimination of complex natural stimuli: can single neurons match behavior? J Neurosci. 2007 Jan 17; 27(3):582-9. PMID: 17234590; PMCID: PMC6672806; DOI: 10.1523/JNEUROSCI.3699-06.2007;

Soto G, Kopell N, Sen K. Network architecture, receptive fields, and neuromodulation: computational and functional implications of cholinergic modulation in primary auditory cortex. J Neurophysiol. 2006 Dec; 96(6):2972-83.View Related Profiles.

Sen, Kamal
Kopell, Nancy

PMID: 16899641

Narayan R, Graña G, Sen K. Distinct time scales in cortical discrimination of natural sounds in songbirds. J Neurophysiol. 2006 Jul; 96(1):252-8. PMID: 16571738; DOI: 10.1152/jn.01257.2005;

Zhou YD, Acker CD, Netoff TI, Sen K, White JA. Increasing Ca2+ transients by broadening postsynaptic action potentials enhances timing-dependent synaptic depression. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):19121-5.View Related Profiles.

White, John
Sen, Kamal

PMID: 16365307; PMCID: PMC1323223; DOI: 10.1073/pnas.0509856103;

Best V, Ozmeral E, Gallun FJ, Sen K, Shinn-Cunningham BG. Spatial unmasking of birdsong in human listeners: energetic and informational factors. J Acoust Soc Am. 2005 Dec; 118(6):3766-73. PMID: 16419821; DOI: 10.1121/1.2130949;

Narayan R, Ergün A, Sen K. Delayed inhibition in cortical receptive fields and the discrimination of complex stimuli. J Neurophysiol. 2005 Oct; 94(4):2970-5. PMID: 15917327; DOI: 10.1152/jn.00144.2005;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 38 publications over 17 distinct years, with a maximum of 4 publications in 2009 and 2020