Guoxian Wei, DDS, PhD
Research Assistant Professor
Boston University Henry M. Goldman School of Dental Medicine
Dept of Molecular & Cell Biology

PhD, Radboud University Nijmegen
MS, University of Illinois
MS, Wuhan University
DDS, Wuhan University

Guoxian Wei, DDS, PhD, is a Research Assistant Professor at the Boston University Goldman School of Dental Medicine. He has published over thirty papers and has over 20 years in microbiological techniques and protein isolation and purification techniques. Additionally, he supervises both staff and students at the university. For 9 years he has been an instructor of the course on Oral Biology Journal Club (SDM OB 850/852) for graduate students and had been a judge for BU Science Day from 2010-2017. Dr. Wei has peer reviewed papers in publications such as the Journal of Antimicrobial Chemotherapy, The European Journal of Oral Sciences, and Pharmaceutical Sciences. He has multiple patents, chapters, and conference presentations published. He has received multiple grants for his articles.

Boston University School of Medicine
Physical Therapy & Athletic Training

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Wei G, Darwish G, Oppenheim FG, Schuppan D, Helmerhorst EJ. Commensal Bacterium Rothia aeria Degrades and Detoxifies Gluten via a Highly Effective Subtilisin Enzyme. Nutrients. 2020 Dec 02; 12(12).View Related Profiles. PMID: 33276655; PMCID: PMC7761627; DOI: 10.3390/nu12123724;
  2. Wei G, Helmerhorst EJ, Darwish G, Blumenkranz G, Schuppan D. Gluten Degrading Enzymes for Treatment of Celiac Disease. Nutrients. 2020 Jul 15; 12(7). PMID: 32679754; PMCID: PMC7400306; DOI: 10.3390/nu12072095;
  3. Darwish G, Helmerhorst EJ, Schuppan D, Oppenheim FG, Wei G. Pharmaceutically modified subtilisins withstand acidic conditions and effectively degrade gluten in vivo. Sci Rep. 2019 05 16; 9(1):7505.View Related Profiles. PMID: 31097786; PMCID: PMC6522598; DOI: 10.1038/s41598-019-43837-9;
  4. Yin C, Zhu B, Zhang T, Liu T, Chen S, Liu Y, Li X, Miao X, Li S, Mi X, Zhang J, Li L, Wei G, Xu ZX, Gao X, Huang C, Wei Z, Goding CR, Wang P, Deng X, Cui R. Pharmacological Targeting of STK19 Inhibits Oncogenic NRAS-Driven Melanomagenesis. Cell. 2019 02 21; 176(5):1113-1127.e16.View Related Profiles. PMID: 30712867
  5. Tian N, Faller L, Leffler DA, Kelly CP, Hansen J, Bosch JA, Wei G, Paster BJ, Schuppan D, Helmerhorst EJ. Salivary Gluten Degradation and Oral Microbial Profiles in Healthy Individuals and Celiac Disease Patients. Appl Environ Microbiol. 2017 Mar 15; 83(6).View Related Profiles. PMID: 28087531; PMCID: PMC5335528; DOI: 10.1128/AEM.03330-16;
  6. Wei G, Tian N, Siezen R, Schuppan D, Helmerhorst EJ. Identification of food-grade subtilisins as gluten-degrading enzymes to treat celiac disease. Am J Physiol Gastrointest Liver Physiol. 2016 Sep 01; 311(3):G571-80.View Related Profiles. PMID: 27469368; PMCID: PMC5076000; DOI: 10.1152/ajpgi.00185.2016;
  7. Wei G, Tian N, Valery AC, Zhong Y, Schuppan D, Helmerhorst EJ. Identification of Pseudolysin (lasB) as an Aciduric Gluten-Degrading Enzyme with High Therapeutic Potential for Celiac Disease. Am J Gastroenterol. 2015 Jun; 110(6):899-908.View Related Profiles. PMID: 25895519; PMCID: PMC4461489; DOI: 10.1038/ajg.2015.97;
  8. Tian N, Wei G, Schuppan D, Helmerhorst EJ. Effect of Rothia mucilaginosa enzymes on gliadin (gluten) structure, deamidation, and immunogenic epitopes relevant to celiac disease. Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15; 307(8):G769-76.View Related Profiles. PMID: 25147233; PMCID: PMC4200315; DOI: 10.1152/ajpgi.00144.2014;
  9. Helmerhorst EJ, Wei G. Experimental Strategy to Discover Microbes with Gluten-degrading Enzyme Activities. Proc SPIE Int Soc Opt Eng. 2014 May 05; 9112.View Related Profiles. PMID: 26113763; PMCID: PMC4477194; DOI: 10.1117/12.2058730;
  10. Fernandez-Feo M, Wei G, Blumenkranz G, Dewhirst FE, Schuppan D, Oppenheim FG, Helmerhorst EJ. The cultivable human oral gluten-degrading microbiome and its potential implications in coeliac disease and gluten sensitivity. Clin Microbiol Infect. 2013 Sep; 19(9):E386-94.View Related Profiles. PMID: 23714165; PMCID: PMC3749263; DOI: 10.1111/1469-0691.12249;
Showing 10 of 37 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 37 publications over 25 distinct years, with a maximum of 4 publications in 1992


Contact for Mentoring:

700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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