Gillian Schiralli Lester, PhD
Postdoctoral Associate (previously held)
Boston University Medical Campus
Infectious Diseases

Gillian M. Schiralli Lester, PhD is a former Postdoctoral Associate at the Chobanian and Avedisian School of Medicine. Currently, she is the Research Assistant Professor in the department of neonatology at University of Rochester. She is interested in the regulation of gene expression and how that relates to disease progression. Her previous studies have centered on investigating cell signaling mechanisms which regulate Human Immunodeficiency Virus (HIV) replication with the goal of identifying novel factors which could then be targeted for therapeutic development. Her current focus is on developing gene delivery strategies to treat acute lung injury.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Steiner LA, Getman M, Schiralli Lester GM, Iqbal MA, Katzman P, Szafranski P, Stankiewicz P, Bhattacharya S, Mariani T, Pryhuber G, Lin X, Young JL, Dean DA, Scheible K. Disruption of normal patterns of FOXF1 expression in a lethal disorder of lung development. J Med Genet. 2020 05; 57(5):296-300. PMID: 31662342
  2. Gagne M, Michaels D, Schiralli Lester GM, Gummuluru S, Wong WW, Henderson AJ. Strength of T cell signaling regulates HIV-1 replication and establishment of latency. PLoS Pathog. 2019 05; 15(5):e1007802.View Related Profiles. PMID: 31116788; PMCID: PMC6548398; DOI: 10.1371/journal.ppat.1007802;
  3. Bai H, Lester GMS, Petishnok LC, Dean DA. Cytoplasmic transport and nuclear import of plasmid DNA. Biosci Rep. 2017 Dec 22; 37(6).View Related Profiles. PMID: 29054961; PMCID: PMC5705778; DOI: 10.1042/BSR20160616;
  4. Graci JD, Michaels D, Chen G, Schiralli Lester GM, Nodder S, Weetall M, Karp GM, Gu Z, Colacino JM, Henderson AJ. Identification of benzazole compounds that induce HIV-1 transcription. PLoS One. 2017; 12(6):e0179100.View Related Profiles. PMID: 28658263; PMCID: PMC5489165; DOI: 10.1371/journal.pone.0179100;
  5. Kaczmarek Michaels K, Wolschendorf F, Schiralli Lester GM, Natarajan M, Kutsch O, Henderson AJ. RNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promoters. Virology. 2015 Dec; 486:7-14.View Related Profiles. PMID: 26379089; PMCID: PMC4679410; DOI: 10.1016/j.virol.2015.08.027;
  6. Natarajan M, Schiralli Lester GM, Lee C, Missra A, Wasserman GA, Steffen M, Gilmour DS, Henderson AJ. Negative elongation factor (NELF) coordinates RNA polymerase II pausing, premature termination, and chromatin remodeling to regulate HIV transcription. J Biol Chem. 2013 Sep 6; 288(36):25995-6003.View Related Profiles. PMID: 23884411; PMCID: PMC3764804; DOI: 10.1074/jbc.M113.496489;
  7. Schiralli Lester GM, Akiyama H, Evans E, Singh J, Gummuluru S, Henderson AJ. Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization. Virology. 2013 Feb 5; 436(1):235-43.View Related Profiles. PMID: 23260110; PMCID: PMC3598624; DOI: 10.1016/j.virol.2012.11.015;
  8. Schiralli Lester GM, Henderson AJ. Mechanisms of HIV Transcriptional Regulation and Their Contribution to Latency. Mol Biol Int. 2012; 2012:614120.View Related Profiles. PMID: 22701796; PMCID: PMC3371693; DOI: 10.1155/2012/614120;
  9. Readinger JA, Schiralli GM, Jiang JK, Thomas CJ, August A, Henderson AJ, Schwartzberg PL. Selective targeting of ITK blocks multiple steps of HIV replication. Proc Natl Acad Sci U S A. 2008 May 6; 105(18):6684-9.View Related Profiles. PMID: 18443296; PMCID: PMC2365562; DOI: 10.1073/pnas.0709659105;
  10. Gekonge BN, Schiralli G, Schlegel RA, Henderson AJ. Signal transduction induced by apoptotic cells inhibits HIV transcription in monocytes/macrophages. J Leukoc Biol. 2006 Oct; 80(4):953-60.View Related Profiles. PMID: 16885500

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 10 publications over 7 distinct years, with a maximum of 2 publications in 2012 and 2017 and 2019


Contact for Mentoring:

72 E. Concord St Building A
Boston MA 02118
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