Chandramouli Chandrasekaran

Chandramouli Chandrasekaran, PhD

Assistant Professor

Boston University College of Arts and Sciences

Psychological and Brain Sciences

PhD, Princeton University
MA, Princeton University
MS, Eberhard Karls Universität Tübingen
BSc, University of Madras

Websites

	Psychological & Brain Sciences Faculty
	Google Scholar
	LinkedIn
	ResearchGate
	Chand Lab

ORCID : 0000-0002-1711-590X

I am an Assistant Professor of Anatomy and Neurobiology and Psychological and Brain Sciences at Boston University and Chobanian and Avedisian School of Medicine.

My research interests are in identifiying the neural dynamical systems mediating decision-making and goal-directed behavior on the basis of uni- and multisensory inputs. My research interests are best illustrated by an example. For instance, what are the neural mechanisms which allow one to press the brakes when the stop light turns red and the gas pedal when the light turns green.

As a PhD student with Asif Ghazanfar at Princeton, I examined how information from visual and auditory cues are combined, a process termed multisensory integration. Before that I was a masters student at the international Max Planck Research School at the University of Tübingen in Germany. I worked with Ian Thornton, Tony Gummer , Martin Giese and Zoe Kourtzi. I also had fun being a programmer with Nikos Logothetis before I moved to Princeton to work with Asif.

Being an academic means a peripatetic lifestyle. I have had the pleasure of living in beautiful academic settings such as Tübingen, Princeton and Stanford for a few years. Much of my time is spent in my lab.

Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Anatomy & Neurobiology

BU Research

Multimodal characterization of prefrontal and premotor circuits underlying perceptual decision making in therhesus monkey
09/01/2021 - 06/30/2026 (Multi-PI)
PI: Chandramouli Chandrasekaran, PhD
NIH/National Institute of Neurological Disorders & Stroke
5R01NS122969-05

Neural Circuit Dynamics Underlying Perceptual Decision Making in the Macaque Dorsolateral Prefrontal Cortex
01/01/2024 - 11/30/2025 (Key Person / Mentor)
NIH/National Institute of Neurological Disorders & Stroke
5F31NS131018-02

Causal Roles of Dorsolateral Prefrontal and Dorsal Premotor Cortex in Perceptual Decision-Making
09/01/2023 - 08/31/2025 (Multi-PI)
PI: Chandramouli Chandrasekaran, PhD
NIH/National Institute of Neurological Disorders & Stroke
1R21NS135361-01

Neural circuit dynamics underlying perceptual decision-making
02/01/2020 - 01/31/2024 (PI)
Whitehall Foundation, Inc.

Organization and Dynamics of Premotor and Prefrontal Cortical Circuits Mediating Goal-Directed Behavior
09/30/2018 - 08/31/2023 (PI)
NIH/National Institute of Neurological Disorders & Stroke
5R00NS092972-05

Neural dynamics underlying integration of sensory, reward and motor effort information in the macaque brain
01/15/2020 - 01/14/2023 (PI)
Brain & Behavior Research Foundation

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Qiang Y, Gu W, Jang D, Shin Y, Shi D, Seo KJ, Li G, Vinnikova S, Wu S, Iyer A, Artoni P, Ryu J, Bai T, Dhawan V, Medalla M, Rosene DL, Moore TL, Koppes AN, Koppes R, Liou JY, Chandrasekaran C, Cui XT, Wang S, Fang H. Monolithic three-dimensional neural probes from deterministic rolling of soft electronics. Nat Electron. 2025 Aug; 8(8):721-737.View Related Profiles.

Chandrasekaran, Chandramouli
Rosene, Douglas
Medalla, Maria
Moore, Tara

PMID: 40951322; PMCID: PMC12425490; DOI: 10.1038/s41928-025-01431-0;

Lee EK, Gül AE, Heller G, Lakunina A, Yu H, Shelton A, Olsen S, Steinmetz NA, Hurwitz C, Jaramillo S, Przytycki PF, Chandrasekaran C. A multimodal approach for visualization and identification of electrophysiological cell types in vivo. bioRxiv. 2025 Jul 31. PMID: 40766549; PMCID: PMC12324179; DOI: 10.1101/2025.07.24.666654;

Genkin M, Shenoy KV, Chandrasekaran C, Engel TA. The dynamics and geometry of choice in the premotor cortex. Nature. 2025 Sep; 645(8079):168-176. PMID: 40562938; PMCID: PMC12408350; DOI: 10.1038/s41586-025-09199-1;

Carr N, Zhu S, Chen X, Lee K, Perliss A, Moore T, Chandrasekaran C. Neuropixels reveal structure-function relationships in monkey V1 in vivo. bioRxiv. 2025 Jun 25. PMID: 40463048; PMCID: PMC12132580; DOI: 10.1101/2025.05.14.653875;

Major AJ, Abdaltawab A, Phillips JM, Wang T, Lee EK, Lichtenfeld MJ, Chandrasekaran C, Saalmann YB, Maier A, Desimone R, Miller EK, Bastos AM, Mendoza-Halliday D. A ubiquitous spectrolaminar motif across independent studies, including Mackey et al.'s own data. bioRxiv. 2025 May 08. PMID: 40654711; PMCID: PMC12247776; DOI: 10.1101/2025.05.07.652644;

Yu H, Lyu H, Xu EY, Windolf C, Lee EK, Yang F, Shelton AM, Olsen S, Minavi S, Winter O, Dyer EL, Chandrasekaran C, Steinmetz NA, Paninski L, Hurwitz C. In vivo cell-type and brain region classification via multimodal contrastive learning. bioRxiv. 2025 Apr 06. PMID: 39574717; PMCID: PMC11580900; DOI: 10.1101/2024.11.05.622159;

Hasnain MA, Birnbaum JE, Ugarte Nunez JL, Hartman EK, Chandrasekaran C, Economo MN. Separating cognitive and motor processes in the behaving mouse. Nat Neurosci. 2025 Mar; 28(3):640-653.View Related Profiles.

Chandrasekaran, Chandramouli
Economo, Michael

PMID: 39905210

Huang Y, Li G, Bai T, Shin Y, Wang X, More AI, Boucher P, Chandrasekaran C, Liu J, Fang H. Flexible electronic-photonic 3D integration from ultrathin polymer chiplets. Npj Flex Electron. 2024; 8. PMID: 39780990; PMCID: PMC11709425; DOI: 10.1038/s41528-024-00344-w;

Boucher PO, Wang T, Carceroni L, Kane G, Shenoy KV, Chandrasekaran C. Initial conditions combine with sensory evidence to induce decision-related dynamics in premotor cortex. Nat Commun. 2023 Oct 16; 14(1):6510. PMID: 37845221; PMCID: PMC10579235; DOI: 10.1038/s41467-023-41752-2;

Hasnain MA, Birnbaum JE, Nunez JLU, Hartman EK, Chandrasekaran C, Economo MN. Separating cognitive and motor processes in the behaving mouse. bioRxiv. 2023 Aug 24.View Related Profiles.

Chandrasekaran, Chandramouli
Economo, Michael

PMID: 37662199; PMCID: PMC10473744; DOI: 10.1101/2023.08.23.554474;

Showing 10 of 41 results. Show More

Genkin M, Shenoy KV, Chandrasekaran C, Engel TA. The dynamics and geometry of choice in premotor cortex. bioRxiv. 2023 Jul 25. PMID: 37546748; PMCID: PMC10401920; DOI: 10.1101/2023.07.22.550183;

Kleinman M, Wang T, Xiao D, Feghhi E, Lee K, Carr N, Li Y, Hadidi N, Chandrasekaran C, Kao JC. A cortical information bottleneck during decision-making. bioRxiv. 2023 Jul 14. PMID: 37502862; PMCID: PMC10369960; DOI: 10.1101/2023.07.12.548742;

Lee K, Carr N, Perliss A, Chandrasekaran C. WaveMAP for identifying putative cell types from in vivo electrophysiology. STAR Protoc. 2023 May 22; 4(2):102320. PMID: 37220000; PMCID: PMC10220268; DOI: 10.1016/j.xpro.2023.102320;

Lee EK, Balasubramanian H, Tsolias A, Anakwe SU, Medalla M, Shenoy KV, Chandrasekaran C. Non-linear dimensionality reduction on extracellular waveforms reveals cell type diversity in premotor cortex. Elife. 2021 08 06; 10.View Related Profiles.

Chandrasekaran, Chandramouli
Medalla, Maria

PMID: 34355695; PMCID: PMC8452311; DOI: 10.7554/eLife.67490;

Peixoto D, Verhein JR, Kiani R, Kao JC, Nuyujukian P, Chandrasekaran C, Brown J, Fong S, Ryu SI, Shenoy KV, Newsome WT. Decoding and perturbing decision states in real time. Nature. 2021 03; 591(7851):604-609. PMID: 33473215

O'Shea DJ, Kalanithi P, Ferenczi EA, Hsueh B, Chandrasekaran C, Goo W, Diester I, Ramakrishnan C, Kaufman MT, Ryu SI, Yeom KW, Deisseroth K, Shenoy KV. Publisher Correction: Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys. Sci Rep. 2019 Dec 05; 9(1):18775. PMID: 31801956; PMCID: PMC6892861; DOI: 10.1038/s41598-019-55025-w;

Casas JP, Chandrasekaran C. openEyeTrack - A high speed multi-threaded eye tracker for head-fixed applications. J Open Source Softw. 2019; 4(42). PMID: 34222770; PMCID: PMC8247665; DOI: 10.21105/joss.01631;

Chandrasekaran C, Hawkins GE. ChaRTr: An R toolbox for modeling choices and response times in decision-making tasks. J Neurosci Methods. 2019 12 01; 328:108432. PMID: 31586868; PMCID: PMC6980795; DOI: 10.1016/j.jneumeth.2019.108432;

Casas JP, Chandrasekaran C. openEyeTrack: A high speed multi-threaded eye tracker for head-fixed applications. Journal of Open Source Software. 2019; 4(42). View Publication

Chandrasekaran C, Blurton SP, Gondan M. Audiovisual detection at different intensities and delays. J Math Psychol. 2019 Aug; 91:159-175. PMID: 31404455; PMCID: PMC6688765; DOI: 10.1016/j.jmp.2019.05.001;

Wang M, Montanède C, Chandrasekaran C, Peixoto D, Shenoy KV, Kalaska JF. Macaque dorsal premotor cortex exhibits decision-related activity only when specific stimulus-response associations are known. Nat Commun. 2019 04 17; 10(1):1793. PMID: 30996222; PMCID: PMC6470163; DOI: 10.1038/s41467-019-09460-y;

Chandrasekaran C, Bray IE, Shenoy KV. Frequency Shifts and Depth Dependence of Premotor Beta Band Activity during Perceptual Decision-Making. J Neurosci. 2019 02 20; 39(8):1420-1435. PMID: 30606756; PMCID: PMC6381246; DOI: 10.1523/JNEUROSCI.1066-18.2018;

O'Shea DJ, Kalanithi P, Ferenczi EA, Hsueh B, Chandrasekaran C, Goo W, Diester I, Ramakrishnan C, Kaufman MT, Ryu SI, Yeom KW, Deisseroth K, Shenoy KV. Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys. Sci Rep. 2018 04 30; 8(1):6775. PMID: 29712920; PMCID: PMC5928036; DOI: 10.1038/s41598-018-24362-7;

Chandrasekaran C, Peixoto D, Newsome WT, Shenoy KV. Laminar differences in decision-related neural activity in dorsal premotor cortex. Nat Commun. 2017 09 20; 8(1):614. PMID: 28931803; PMCID: PMC5607001; DOI: 10.1038/s41467-017-00715-0;

Chandrasekaran C. Computational principles and models of multisensory integration. Curr Opin Neurobiol. 2017 04; 43:25-34. PMID: 27918886; PMCID: PMC5447489; DOI: 10.1016/j.conb.2016.11.002;

O'Shea DJ, Trautmann E, Chandrasekaran C, Stavisky S, Kao JC, Sahani M, Ryu S, Deisseroth K, Shenoy KV. The need for calcium imaging in nonhuman primates: New motor neuroscience and brain-machine interfaces. Exp Neurol. 2017 01; 287(Pt 4):437-451. PMID: 27511294; PMCID: PMC5154795; DOI: 10.1016/j.expneurol.2016.08.003;

Chandrasekaran C, Lemus L, Ghazanfar AA. Dynamic faces speed up the onset of auditory cortical spiking responses during vocal detection. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):E4668-77. PMID: 24218574; PMCID: PMC3845123; DOI: 10.1073/pnas.1312518110;

Chandrasekaran C, Ghazanfar AA. Principles of neural coding (Quian Quiroga R, Panzeri S, eds.). Coding Across Sensory Modalities: Integrating the Dynamic Face With The Voice. Taylor & Francis Press. 2012.
Ghazanfar AA, Chandrasekaran C. New Handbook of Multisensory Processes (Stein BE, ed.). Non-human Primate Models of Audiovisual Communication. MIT Press. 2012; 407-420.
Ghazanfar AA, Chandrasekaran C. Neural Correlates of Auditory Cognition, Springer Handbook for Auditory Research (SHAR) (Cohen YE, Popper AN, Fay RR, Eds.). The Influence of Vision on Auditory Communication in Primates. Springer Press. 2012.

Chandrasekaran C, Lemus L, Trubanova A, Gondan M, Ghazanfar AA. Monkeys and humans share a common computation for face/voice integration. PLoS Comput Biol. 2011 Sep; 7(9):e1002165. PMID: 21998576; PMCID: PMC3182859; DOI: 10.1371/journal.pcbi.1002165;

Chandrasekaran C, Ghazanfar AA. When what you see is not what you hear. Nat Neurosci. 2011 Jun; 14(6):675-6. PMID: 21613995; DOI: 10.1038/nn.2843;

Chandrasekaran C, Turesson HK, Brown CH, Ghazanfar AA. The influence of natural scene dynamics on auditory cortical activity. J Neurosci. 2010 Oct 20; 30(42):13919-31. PMID: 20962214; PMCID: PMC3005258; DOI: 10.1523/JNEUROSCI.3174-10.2010;

Ghazanfar AA, Chandrasekaran C, Morrill RJ. Dynamic, rhythmic facial expressions and the superior temporal sulcus of macaque monkeys: implications for the evolution of audiovisual speech. Eur J Neurosci. 2010 May; 31(10):1807-17. PMID: 20584185; PMCID: PMC2898901; DOI: 10.1111/j.1460-9568.2010.07209.x;

Chandrasekaran, C, Turner L, Bülthoff HH & Thornton, IM. Attentional networks and biological motion. Psychologia. 2010; 43(1):5-20.

Chandrasekaran C, Trubanova A, Stillittano S, Caplier A, Ghazanfar AA. The natural statistics of audiovisual speech. PLoS Comput Biol. 2009 Jul; 5(7):e1000436. PMID: 19609344; PMCID: PMC2700967; DOI: 10.1371/journal.pcbi.1000436;

Chandrasekaran C, Ghazanfar AA. Different neural frequency bands integrate faces and voices differently in the superior temporal sulcus. J Neurophysiol. 2009 Feb; 101(2):773-88. PMID: 19036867; PMCID: PMC2657063; DOI: 10.1152/jn.90843.2008;

Maier JX, Chandrasekaran C, Ghazanfar AA. Integration of bimodal looming signals through neuronal coherence in the temporal lobe. Curr Biol. 2008 Jul 08; 18(13):963-8. PMID: 18585039; DOI: 10.1016/j.cub.2008.05.043;

Ghazanfar AA, Chandrasekaran C, Logothetis NK. Interactions between the superior temporal sulcus and auditory cortex mediate dynamic face/voice integration in rhesus monkeys. J Neurosci. 2008 Apr 23; 28(17):4457-69. PMID: 18434524; PMCID: PMC2663804; DOI: 10.1523/JNEUROSCI.0541-08.2008;

Ghazanfar AA, Chandrasekaran CF. Paving the way forward: integrating the senses through phase-resetting of cortical oscillations. Neuron. 2007 Jan 18; 53(2):162-4. PMID: 17224399; DOI: 10.1016/j.neuron.2007.01.003;

Chandrasekaran C, Canon V, Dahmen JC, Kourtzi Z, Welchman AE. Neural correlates of disparity-defined shape discrimination in the human brain. J Neurophysiol. 2007 Feb; 97(2):1553-65. PMID: 17151220; DOI: 10.1152/jn.01074.2006;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 41 publications over 16 distinct years, with a maximum of 7 publications in 2019 and 2025