Michael Economo | Profiles RNS

Michael Nicholas Economo, PhD

Assistant Professor

Boston University College of Engineering

Biomedical Engineering

PhD, Boston University
BA, Duke University
BSE, Duke University

Websites

	BU College of Engineering
	BU Center for Systems Neuroscience
	LinkedIn
	Google Scholar

ORCID : 0000-0001-9893-1505

Dr. Economo is an Assistant Professor of Biomedical Engineering at Boston University College of Engineering. Dr. Economo received his PhD from Boston University in Biomedical Engineering, and he recently received the Whitehall Foundation Young Investigator Award (2021) and the Klingenstein-Simons Award in Neuroscience (2020). In his lab, he studies the structure and function of the neural circuits distributed across the brain that control movement. His research leverages cutting edge optical, electrophysiological, and genetic tools for recording and manipulating neural activity during behavior and for illuminating the structure of neural circuits.

BU Research

Career: High-Level control of low-level circuits in the mammalian motor system
04/01/2023 - 03/31/2028 (PI)
National Science Foundation
IOS-2239412

Linking motor cortex activity and movement in the mouse orofacial system.
02/01/2022 - 01/31/2027 (PI)
NIH/National Institute of Neurological Disorders & Stroke
3R01NS121409-02S1

The descending control of movement initiation by the motor cortex
07/01/2020 - 07/01/2025 (PI)
The Esther A. & Joseph Klingenstein Fund, Inc.

High-throughput mapping of synaptic connectivity between transcriptomically defined cell types
05/01/2022 - 04/30/2025 (PI)
NIH/National Institute of Mental Health
1RF1MH126882-01A1

Investigating the control of movements by subspaces and cell types in the mouse orofacial system
03/01/2021 - 02/25/2025 (PI)
Whitehall Foundation, Inc.

Reverse engineering the brain stem circuits that govern exploratory behavior
06/01/2020 - 05/31/2023 (Subcontract PI)
University of California, San Diego NIH NINDS
5U19NS107466

Title

Yr	Title	Project-Sub Proj	Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Vincent JP, Economo MN. Assessing cross-contamination in spike-sorted electrophysiology data. bioRxiv. 2023 Dec 23. PMID: 38187738; PMCID: PMC10769346; DOI: 10.1101/2023.12.21.572882;

Kleinfeld D, Deschênes M, Economo MN, Elbaz M, Golomb D, Liao SM, O'Connor DH, Wang F. Low- and high-level coordination of orofacial motor actions. Curr Opin Neurobiol. 2023 Dec; 83:102784. PMID: 37757586

Hasnain MA, Birnbaum JE, Nunez JLU, Hartman EK, Chandrasekaran C, Economo MN. Separating cognitive and motor processes in the behaving mouse. bioRxiv. 2023 Aug 24. PMID: 37662199; PMCID: PMC10473744; DOI: 10.1101/2023.08.23.554474;

Weber TD, Moya MV, Kiliç K, Mertz J, Economo MN. High-speed multiplane confocal microscopy for voltage imaging in densely labeled neuronal populations. Nat Neurosci. 2023 Sep; 26(9):1642-1650.View Related Profiles.

Mertz, Jerome
Economo, Michael

PMID: 37604887

Xiao S, Cunningham WJ, Kondabolu K, Lowet E, Moya MV, Mount R, Ravasio C, Economo MN, Han X, Mertz J. Large-scale deep tissue voltage imaging with targeted illumination confocal microscopy. bioRxiv. 2023 Jul 21.View Related Profiles.

Mertz, Jerome
Economo, Michael

PMID: 37502929; PMCID: PMC10370169; DOI: 10.1101/2023.07.21.548930;

Abdelfattah AS, Zheng J, Singh A, Huang YC, Reep D, Tsegaye G, Tsang A, Arthur BJ, Rehorova M, Olson CVL, Shuai Y, Zhang L, Fu TM, Milkie DE, Moya MV, Weber TD, Lemire AL, Baker CA, Falco N, Zheng Q, Grimm JB, Yip MC, Walpita D, Chase M, Campagnola L, Murphy GJ, Wong AM, Forest CR, Mertz J, Economo MN, Turner GC, Koyama M, Lin BJ, Betzig E, Novak O, Lavis LD, Svoboda K, Korff W, Chen TW, Schreiter ER, Hasseman JP, Kolb I. Sensitivity optimization of a rhodopsin-based fluorescent voltage indicator. Neuron. 2023 May 17; 111(10):1547-1563.e9.View Related Profiles.

Mertz, Jerome
Economo, Michael

PMID: 37015225; PMCID: PMC10280807; DOI: 10.1016/j.neuron.2023.03.009;

Liu LD, Chen S, Hou H, West SJ, Faulkner M, Economo MN, Li N, Svoboda K. Accurate Localization of Linear Probe Electrode Arrays across Multiple Brains. eNeuro. 2021 Nov-Dec; 8(6). PMID: 34697075; PMCID: PMC8597948; DOI: 10.1523/ENEURO.0241-21.2021;

Finkelstein A, Fontolan L, Economo MN, Li N, Romani S, Svoboda K. Publisher Correction: Attractor dynamics gate cortical information flow during decision-making. Nat Neurosci. 2021 Jun; 24(6):897. PMID: 34012095

Finkelstein A, Fontolan L, Economo MN, Li N, Romani S, Svoboda K. Attractor dynamics gate cortical information flow during decision-making. Nat Neurosci. 2021 06; 24(6):843-850. PMID: 33875892

Ueda HR, Dodt HU, Osten P, Economo MN, Chandrashekar J, Keller PJ. Whole-Brain Profiling of Cells and Circuits in Mammals by Tissue Clearing and Light-Sheet Microscopy. Neuron. 2020 05 06; 106(3):369-387. PMID: 32380050; PMCID: PMC7213014; DOI: 10.1016/j.neuron.2020.03.004;

Showing 10 of 32 results. Show More

Gao Z, Thomas AM, Economo MN, Abrego AM, Svoboda K, De Zeeuw CI, Li N. Response to "Fallacies of Mice Experiments". Neuroinformatics. 2019 10; 17(4):475-478. PMID: 31377994; PMCID: PMC6842428; DOI: 10.1007/s12021-019-09433-y;

Winnubst J, Bas E, Ferreira TA, Wu Z, Economo MN, Edson P, Arthur BJ, Bruns C, Rokicki K, Schauder D, Olbris DJ, Murphy SD, Ackerman DG, Arshadi C, Baldwin P, Blake R, Elsayed A, Hasan M, Ramirez D, Dos Santos B, Weldon M, Zafar A, Dudman JT, Gerfen CR, Hantman AW, Korff W, Sternson SM, Spruston N, Svoboda K, Chandrashekar J. Reconstruction of 1,000 Projection Neurons Reveals New Cell Types and Organization of Long-Range Connectivity in the Mouse Brain. Cell. 2019 09 19; 179(1):268-281.e13. PMID: 31495573; PMCID: PMC6754285; DOI: 10.1016/j.cell.2019.07.042;

Economo MN, Winnubst J, Bas E, Ferreira TA, Chandrashekar J. Single-neuron axonal reconstruction: The search for a wiring diagram of the brain. J Comp Neurol. 2019 09 01; 527(13):2190-2199. PMID: 30859571

Tasic B, Yao Z, Graybuck LT, Smith KA, Nguyen TN, Bertagnolli D, Goldy J, Garren E, Economo MN, Viswanathan S, Penn O, Bakken T, Menon V, Miller J, Fong O, Hirokawa KE, Lathia K, Rimorin C, Tieu M, Larsen R, Casper T, Barkan E, Kroll M, Parry S, Shapovalova NV, Hirschstein D, Pendergraft J, Sullivan HA, Kim TK, Szafer A, Dee N, Groblewski P, Wickersham I, Cetin A, Harris JA, Levi BP, Sunkin SM, Madisen L, Daigle TL, Looger L, Bernard A, Phillips J, Lein E, Hawrylycz M, Svoboda K, Jones AR, Koch C, Zeng H. Shared and distinct transcriptomic cell types across neocortical areas. Nature. 2018 11; 563(7729):72-78. PMID: 30382198; PMCID: PMC6456269; DOI: 10.1038/s41586-018-0654-5;

Economo MN, Viswanathan S, Tasic B, Bas E, Winnubst J, Menon V, Graybuck LT, Nguyen TN, Smith KA, Yao Z, Wang L, Gerfen CR, Chandrashekar J, Zeng H, Looger LL, Svoboda K. Distinct descending motor cortex pathways and their roles in movement. Nature. 2018 11; 563(7729):79-84. PMID: 30382200

Gao Z, Davis C, Thomas AM, Economo MN, Abrego AM, Svoboda K, De Zeeuw CI, Li N. A cortico-cerebellar loop for motor planning. Nature. 2018 11; 563(7729):113-116. PMID: 30333626; PMCID: PMC6212318; DOI: 10.1038/s41586-018-0633-x;

Díaz-Quesada M, Youngstrom IA, Tsuno Y, Hansen KR, Economo MN, Wachowiak M. Inhalation Frequency Controls Reformatting of Mitral/Tufted Cell Odor Representations in the Olfactory Bulb. J Neurosci. 2018 02 28; 38(9):2189-2206.View Related Profiles.

Economo, Michael
Tsuno, Yusuke

PMID: 29374137; PMCID: PMC5830510; DOI: 10.1523/JNEUROSCI.0714-17.2018;

Gerfen CR, Economo MN, Chandrashekar J. Long distance projections of cortical pyramidal neurons. J Neurosci Res. 2018 09; 96(9):1467-1475. PMID: 27862192

Economo MN, Hansen KR, Wachowiak M. Control of Mitral/Tufted Cell Output by Selective Inhibition among Olfactory Bulb Glomeruli. Neuron. 2016 07 20; 91(2):397-411. PMID: 27346531

Economo MN, Clack NG, Lavis LD, Gerfen CR, Svoboda K, Myers EW, Chandrashekar J. A platform for brain-wide imaging and reconstruction of individual neurons. Elife. 2016 Jan 20; 5:e10566. PMID: 26796534

Gee JM, Gibbons MB, Taheri M, Palumbos S, Morris SC, Smeal RM, Flynn KF, Economo MN, Cizek CG, Capecchi MR, Tvrdik P, Wilcox KS, White JA. Imaging activity in astrocytes and neurons with genetically encoded calcium indicators following in utero electroporation. Front Mol Neurosci. 2015; 8:10.View Related Profiles.

White, John
Economo, Michael

PMID: 25926768; PMCID: PMC4397926; DOI: 10.3389/fnmol.2015.00010;

Gee JM, Smith NA, Fernandez FR, Economo MN, Brunert D, Rothermel M, Morris SC, Talbot A, Palumbos S, Ichida JM, Shepherd JD, West PJ, Wachowiak M, Capecchi MR, Wilcox KS, White JA, Tvrdik P. Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse. Neuron. 2014 Sep 03; 83(5):1058-72.View Related Profiles.

Fernandez, Fernando
White, John
Economo, Michael

PMID: 25155958; PMCID: PMC4156920; DOI: 10.1016/j.neuron.2014.07.024;

Magnani C, Economo MN, White JA, Moore LE. Nonlinear properties of medial entorhinal cortex neurons reveal frequency selectivity during multi-sinusoidal stimulation. Front Cell Neurosci. 2014; 8:239.View Related Profiles.

White, John
Economo, Michael

PMID: 25191226; PMCID: PMC4137241; DOI: 10.3389/fncel.2014.00239;

Economo MN, Martínez JJ, White JA. Membrane potential-dependent integration of synaptic inputs in entorhinal stellate neurons. Hippocampus. 2014 Dec; 24(12):1493-505.View Related Profiles.

White, John
Economo, Michael

PMID: 25044927; PMCID: PMC4236276; DOI: 10.1002/hipo.22329;

Wachowiak M, Economo MN, Díaz-Quesada M, Brunert D, Wesson DW, White JA, Rothermel M. Optical dissection of odor information processing in vivo using GCaMPs expressed in specified cell types of the olfactory bulb. J Neurosci. 2013 Mar 20; 33(12):5285-300.View Related Profiles.

White, John
Economo, Michael

PMID: 23516293; PMCID: PMC3690468; DOI: 10.1523/JNEUROSCI.4824-12.2013;

Economo MN, Martinez JJ, White JA. Neural Engineering, B. He (Ed.). Neural Modeling. Springer. 2013.

Kispersky TJ, Fernandez FR, Economo MN, White JA. Spike resonance properties in hippocampal O-LM cells are dependent on refractory dynamics. J Neurosci. 2012 Mar 14; 32(11):3637-51.View Related Profiles.

Fernandez, Fernando
White, John
Economo, Michael

PMID: 22423087; PMCID: PMC3316126; DOI: 10.1523/JNEUROSCI.1361-11.2012;

Economo MN, White JA. Membrane properties and the balance between excitation and inhibition control gamma-frequency oscillations arising from feedback inhibition. PLoS Comput Biol. 2012 Jan; 8(1):e1002354.View Related Profiles.

White, John
Economo, Michael

PMID: 22275859; PMCID: PMC3261914; DOI: 10.1371/journal.pcbi.1002354;

Kispersky TJ, Economo MN, Randeria P, White JA. GenNet: A Platform for Hybrid Network Experiments. Front Neuroinform. 2011; 5:11.View Related Profiles.

White, John
Economo, Michael

PMID: 21845179; PMCID: PMC3146038; DOI: 10.3389/fninf.2011.00011;

Economo MN, Fernandez FR, White JA. Dynamic clamp: alteration of response properties and creation of virtual realities in neurophysiology. J Neurosci. 2010 Feb 17; 30(7):2407-13.View Related Profiles.

Fernandez, Fernando
White, John
Economo, Michael

PMID: 20164323; PMCID: PMC2837935; DOI: 10.1523/JNEUROSCI.5954-09.2010;

White JA, Fernandez FR, Economo MN, and Kispersky TJ. Dynamic Clamp: From principles to applications, A. Destexhe and T. Bal (Eds.). Using “hard” real-time dynamic clamp to study cellular and network mechanisms of synchronization in the hippocampal formation. Springer. 2009.

Burton BG, Economo MN, Lee GJ, White JA. Development of theta rhythmicity in entorhinal stellate cells of the juvenile rat. J Neurophysiol. 2008 Dec; 100(6):3144-57.View Related Profiles.

White, John
Economo, Michael

PMID: 18829850; PMCID: PMC2604849; DOI: 10.1152/jn.90424.2008;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 32 publications over 14 distinct years, with a maximum of 6 publications in 2023

Bar chart showing 32 publications over 14 distinct years, with a maximum of 6 publications in 2023

Year	Publications
2008	1
2009	1
2010	1
2011	1
2012	2
2013	2
2014	3
2015	1
2016	3
2018	4
2019	3
2020	1
2021	3
2023	6

Media Mentions

Kilachand Fund Awards Go to Crystal Rib Cage and Brain Connection Projects

BU Today 10/3/2023

2021 Whitehall foundation: Whitehall Foundation Award in Neuroscience

2020 Klingenstein Fund/Simons Foundation: Klingenstein-Simons Award in Neuroscience

2014 Association for Chemoreception Sciences: Polak Young Investigator Award

2012 NIH/NIDCD: Ruth L. Kirschstein Postdoctoral Fellowship Award

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Boston MA 02215
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